I found this very interesting. Some studies have found an association between diagonal earlobe creases, also known as Frank's sign, and coronary artery disease (CAD).
Two new hydroxylated ethacrylic acid derivatives and 11 new hydroxylated tiglic acid derivatives, along with one known compound, were isolated from Enkianthus chinensis, with their structures and absolute configurations determined through various spectroscopic and chemical methods, marking the first investigation of secondary metabolites from this species, and compounds 3 and 12 showed potent anti-inflammatory activities.
The study revealed an alarmingly high prevalence of HIV infection among commercial plasma donors. This poses a significant risk of transmission to their spouses and future children. It is crucial to alert plasma donors about the dangers of HIV infection and its potential spread to their families and others. Other countries can learn from China's experience in mitigating the risk of HIV transmission through plasma donation.
This study analyzed changes in 15-lipoxygenase and cyclooxygenase isoforms and related cytokines in SARS-CoV-2 infections, finding significant elevations in 15-LOX-1 and 15-LOX-2 expression in male patients with severe infection and increases in COX isoforms correlated with disease severity. These findings highlight the regulatory network involving COX and 15-LOX enzymes, contributing to understanding SARS-CoV-2 pathogenicity and informing potential pharmaceutical approaches.
Good paper! This study reveals that copolymers containing sulfobetaine methacrylate (SBMA) units fail to provide poly(vinylidene fluoride) (PVDF) membranes with antifouling properties after steam sterilization, whereas those containing sulfobetaine methacrylamide (SBAA) units maintain their antifouling properties. This is due to the stability of SBAA units during sterilization, making SBAA-derivatives preferable for improving membrane fouling resistance in applications requiring steam sterilization.
Electrospun nanofibers with completely interconnected pore structures are ideal for thin-film nanofibrous composite (TFNC) nanofiltration membranes, but poor adhesion between the substrate and selective layer limits their application. This study demonstrates that a polyethyleneimine (PEI)/polyacrylonitrile (PAN) transition layer enhances membrane hydrophilicity, provides additional reaction sites for interfacial polymerization, and prevents polymerization in nanofiber pores, resulting in a defect-free selective layer with excellent separation performance and long-term stability.
How does the gel-less synthesis method for SSZ-13 membranes improve material efficiency and control over membrane thickness compared to conventional hydrothermal synthesis, and what factors are critical for achieving high CO2 permeance and selectivity?
How does the improved methodology for evaluating the nominal molecular weight cutoff (MWCO) of large pore size ultrafiltration membranes based on dextran retention measurements enhance the selection process for targeted separations in downstream processing?
What are the benefits of using the melt-spinning and stretching (MS-S) technique based on the interface pore theory for preparing poly(vinylidene fluoride) (PVDF) hollow fiber membranes compared to traditional solvent-based methods?
Great paper! Chronopotentiometry with constant current density is effective for characterizing ion-exchange membranes (IEMs). Our study shows that in the presence of Ca2+ or Mg2+ ions, the chronopotentiograms (ChPs) of CMX and MK-40 cation-exchange membranes display a peak after the transition time, attributed to increased coion transfer and concentration polarization, leading to reduced resistance in the diffusion layer.
Phosphonated aromatic polymers offer high thermal and chemical stability as proton exchange membranes (PEMs) but generally require enhanced conductivity for electrochemical applications. This study presents poly(p-terphenyl perfluoroalkylene)s functionalized with highly acidic perfluorophenylphosphonic acid, demonstrating high proton conductivity and excellent stability, making them suitable for use in fuel cells and water electrolyzers.
Eric Topol has published over 1300 peer-reviewed articles, with more than 300,000 citations, elected to the National Academy of Medicine, and is one of the top 10 most cited researchers in medicine. His principal scientific focus has been on the use of genomic and digital data, along with artificial intelligence, to individualize medicine.
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