Progress in artificial metallonucleases

Synergy between quantum dots and 1,10-phenanthroline–copper(ii) complex towards cleaving DNA

(2011) Javier Hernández-Gil et al.   CHEMICAL COMMUNICATIONS

Artificial DNA cutters for DNA manipulation and genome engineering

(2011) Yuichiro Aiba et al.   CHEMICAL SOCIETY REVIEWS

Artificial Restriction DNA Cutters to Promote Homologous Recombination in Human Cells

(2011) Hitoshi Katada et al.   CURRENT GENE THERAPY

Efficient double-strand cleavage of DNA mediated by Zn(ii)-based artificial nucleases

(2011) Jing Qian et al.   DALTON TRANSACTIONS

Phosphatase-like activity, DNA binding, DNA hydrolysis, anticancer and lactate dehydrogenase inhibition activity promoting by a new bis–phenanthroline dicopper(ii) complex

(2011) Sellamuthu Anbu et al.   DALTON TRANSACTIONS

Biological evaluation of a novel water soluble sulphur bridged binuclear copper(II) thiosemicarbazone complex

(2011) Duraisamy Senthil Raja et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

DNA Cleavage by the Photocontrolled Cooperation of ZnIICenters in an Azobenzene-Linked Dizinc Complex

(2011) Anangamohan Panja et al.   INORGANIC CHEMISTRY

Synthesis, Characterization, Interaction with DNA, and Cytotoxic Effect in Vitro of New Mono- and Dinuclear Pd(II) and Pt(II) Complexes with Benzo[d]thiazol-2-amine As the Primary Ligand

(2011) EnJun Gao et al.   INORGANIC CHEMISTRY

Synthesis, crystal structure and nuclease activity of a new Mn(II) complex involving 2-(2-1H-imidazolyl)-1H-imdazolium ligand

(2011) Yan-Ping Li et al.   INORGANIC CHEMISTRY COMMUNICATIONS

Dicopper(II) complexes showing DNA hydrolase activity and monomeric adduct formation with bis(4-nitrophenyl)phosphate

(2011) Mithun Roy et al.   INORGANICA CHIMICA ACTA

Vesicles and Micelles from Amphiphilic Zinc(II)–Cyclen Complexes as Highly Potent Promoters of Hydrolytic DNA Cleavage

(2011) Benjamin Gruber et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Factors Influencing the DNA Nuclease Activity of Iron, Cobalt, Nickel, and Copper Chelates

(2011) Jeff C. Joyner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cleavage of RNA phosphodiester bonds by small molecular entities: a mechanistic insight

(2011) Harri Lönnberg   ORGANIC & BIOMOLECULAR CHEMISTRY

Cytotoxic copper(II) complex of tripyridoquinoxaline with DNA hydrolase activity

(2011) V.M. Manikandamathavan et al.   POLYHEDRON

DNA Cleavage System of Nanosized Graphene Oxide Sheets and Copper Ions

(2010) Hongliu Ren et al.   ACS Nano

Artificial Transcription Factors which Mediate Double-Strand DNA Cleavage

(2010) Chao Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

DNA cleavage by the Cu(ii) complex of the DNA-intercalating 9-bis(pyridin-2-ylmethyl)aminobenzo[b]quinolizinium

(2010) Maoqun Tian et al.   DALTON TRANSACTIONS

An effective approach to artificial nucleases using copper(ii) complexes bearing nucleobases

(2010) Jin-Tao Wang et al.   DALTON TRANSACTIONS

Structural, electrochemical, phosphate-hydrolysis, DNA binding and cleavage studies of new macrocyclic binuclear nickel(ii) complexes

(2010) Sellamuthu Anbu et al.   DALTON TRANSACTIONS

Synthesis, Crystal Structure, DNA Binding, and Hydrolytic Cleavage Activity of a Manganese(II) Complex

(2010) Jing Qian et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Synthesis, Structure, and Phosphatase-Like Activity of a New Trinuclear Gd Complex with the Unsymmetrical Ligand H3L As a Model for Nucleases

(2010) Maryene A. Camargo et al.   INORGANIC CHEMISTRY

Synthesis, Structure, and DNA Cleavage Properties of Copper(II) Complexes of 1,4,7-Triazacyclononane Ligands Featuring Pairs of Guanidine Pendants

(2010) Linda Tjioe et al.   INORGANIC CHEMISTRY

Metal complexes of modified cyclen as catalysts for hydrolytic restriction of plasmid DNA

(2010) Joel A. Krauser et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Hydrolytic cleavage of double-strand DNA by the water-soluble dicobalt(III) complexes of 1,4,7-Triazacyclononane-N-acetate

(2010) Jing Qian et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Cleavage of an RNA Model Catalyzed by Dinuclear Zn(II) Complexes Containing Rate-Accelerating Pendants. Comparison of the Catalytic Benefits of H-Bonding and Hydrophobic Substituents

(2010) Mark F. Mohamed et al.   JOURNAL OF ORGANIC CHEMISTRY

Demonstration of Prominent Cu(II)-Promoted Leaving Group Stabilization of the Cleavage of a Homologous Set of Phosphate Mono-, Di-, and Triesters in Methanol

(2010) C. Tony Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

One is enough: insights into the two-metal ion nuclease mechanism from global analysis and computational studies

(2010) Cynthia M. Dupureur   Metallomics

Oxidative and hydrolytic DNA cleavage by Cu(II) complexes of salicylidene tyrosine schiff base and 1,10 phenanthroline/bipyridine

(2010) Pulimamidi Rabindra Reddy et al.   POLYHEDRON

Phosphate diesters and DNA hydrolysis by dinuclear Zn(II) complexes featuring a disulfide bridge and H-bond donors

(2010) Valentina Lombardo et al.   TETRAHEDRON

Novel zinc finger nuclease created by combining the Cys2His2- and His4-type zinc finger domains

(2009) Shigeru Negi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Bisintercalator-containing dinuclear iron(III) complex: An efficient artificial nuclease

(2009) Xiaoqiang Chen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Artificial Restriction DNA Cutters as New Tools for Gene Manipulation

(2009) Hitoshi Katada et al.   CHEMBIOCHEM

Homologous recombination in human cells using artificial restriction DNA cutter

(2009) Hitoshi Katada et al.   CHEMICAL COMMUNICATIONS

Oxidation of an Oligonucleotide-Bound CeIII/Multiphosphonate Complex for Site-Selective DNA Scission

(2009) Tuomas Lönnberg et al.   CHEMISTRY-A EUROPEAN JOURNAL

DNA binding and cleavage activity of quercetin nickel(ii) complex

(2009) Jun Tan et al.   DALTON TRANSACTIONS

Investigation of the Effect of Oxy Bridging Groups in Dinuclear Zn(II) Complexes that Catalyze the Cleavage of a Simple Phosphate Diester RNA Analogue

(2009) Mark F. Mohamed et al.   INORGANIC CHEMISTRY

Induction of Cell Death by Ternary Copper(II) Complexes ofl-Tyrosine and Diimines: Role of Coligands on DNA Binding and Cleavage and Anticancer Activity

(2009) Sethu Ramakrishnan et al.   INORGANIC CHEMISTRY

Mixed-Ligand Copper(II) Maltolate Complexes: Synthesis, Characterization, DNA Binding and Cleavage, and Cytotoxicity

(2009) Archika Barve et al.   INORGANIC CHEMISTRY

Phosphodiester hydrolysis and specific DNA binding and cleavage promoted by guanidinium-functionalized zinc complexes

(2009) Juan He et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

A synthetic dinuclear copper(II) hydrolase and its potential as antitumoral: Cytotoxicity, cellular uptake, and DNA cleavage

(2009) Nicolás A. Rey et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Four new copper(II) complexes with 1,3-tpbd ligand: Synthesis, crystal structures, magnetism, oxidative and hydrolytic cleavage of pBR322 DNA

(2009) Dong-Dong Li et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Dinuclear Zn(II) Complex Promotes Cleavage and Isomerization of 2-Hydroxypropyl Alkyl Phosphates by a Common Cyclic Phosphate Intermediate

(2009) Wing Yin Tsang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Insights on Nuclease Mechanism: The Role of Proximal Ammonium Group on Phosphate Esters Cleavage

(2009) Renato Bonomi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Origin of High Fidelity in Target-Sequence Recognition by PNA−Ce(IV)/EDTA Combinations as Site-Selective DNA Cutters

(2009) Yoshitaka Miyajima et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydrolytic cleavage of DNA promoted by cobalt(III)–tetraamine complexes: Synthesis and characterization of carbonatobis[2-(2-pyridylethyl)]-(2-pyridylmethyl)aminecobalt(III) perchlorate

(2009) Wu Xu et al.   POLYHEDRON

DNA cleavage activities of tetraazamacrocyclic oxamido nickel(II) complexes

(2009) Li-Na Zhu et al.   POLYHEDRON

Phosphate Binding Energy and Catalysis by Small and Large Molecules

(2008) Janet R. Morrow et al.   ACCOUNTS OF CHEMICAL RESEARCH

DNA Binding, Cleavage, and Cytotoxic Activity of the Preorganized Dinuclear Zinc(II) Complex of Triazacyclononane Derivatives

(2008) Xin Sheng et al.   BIOCONJUGATE CHEMISTRY

DNA binding, cytotoxicity, apoptotic inducing activity, and molecular modeling study of quercetin zinc(II) complex

(2008) Jun Tan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and biological evaluation of the Zn (II)–IDB complexes appended with oligopolyamide as potent artificial nuclease

(2008) Chao Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and DNA cleavage activity of a bifunctional intercalator-linked copper(ii) macrocycle

(2008) Ta-Sheng Andrew Tseng et al.   CHEMICAL COMMUNICATIONS

Roles of metal ions in nucleases

(2008) Cynthia M Dupureur   CURRENT OPINION IN CHEMICAL BIOLOGY

Double-strand DNA cleavage by copper complexes of 2,2′-dipyridyl with guanidinium/ammonium pendants

(2008) Juan He et al.   DALTON TRANSACTIONS

DNA hydrolytic cleavage catalyzed by synthetic multinuclear metallonucleases

(2008) Changlin Liu et al.   DALTON TRANSACTIONS

Binuclear Copper(II) Chelates with Heptadentate Ligands: Synthesis, Structure, Magnetic Properties, DFT Studies, and Catecholase and Hydrolytic DNA Cleavage Activity

(2008) Atanu Banerjee et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Photocontrol of Spatial Orientation and DNA Cleavage Activity of Copper(II)-Bound Dipeptides Linked by an Azobenzene Derivative

(2008) Halan Prakash et al.   INORGANIC CHEMISTRY

Tuning the Activity of Zn(II) Complexes in DNA Cleavage: Clues for Design of New Efficient Metallo-Hydrolases

(2008) Carla Bazzicalupi et al.   INORGANIC CHEMISTRY

Two novel zinc complexes of disubstituted 2,2′-bipyridine with ammonium groups as artificial nucleases

(2008) Ji-Hui Li et al.   INORGANIC CHEMISTRY COMMUNICATIONS

A new μ-oxo di-iron complex with suitable features to mimic metallohydrolase activity: X-ray molecular structure, aqua solution behavior and nuclease activity of the complex [Fe(HPClNOL)(SO4)]2-μ-oxo

(2008) Gabrieli L. Parrilha et al.   INORGANIC CHEMISTRY COMMUNICATIONS

Structure, speciation, DNA binding and nuclease activity of two bipyridyl-zinc complexes bearing trimethylaminomethyl groups

(2008) Ji-Hui Li et al.   INORGANICA CHIMICA ACTA

Dineopentyl Phosphate Hydrolysis: Evidence for Stepwise Water Attack

(2008) Shina C. L. Kamerlin et al.   JOURNAL OF ORGANIC CHEMISTRY

Enzyme-like Acceleration for the Hydrolysis of a DNA Model Promoted by a Dinuclear Zn(II) Catalyst in Dilute Aqueous Ethanol

(2008) C. Tony Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biomimetic Cleavage of RNA Models Promoted by a Dinuclear Zn(II) Complex in Ethanol. Greater than 30 kcal/mol Stabilization of the Transition State for Cleavage of a Phosphate Diester

(2008) C. Tony Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cleavage and Isomerization of UpU Promoted by Dinuclear Metal Ion Complexes

(2008) Heidi Linjalahti et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphate Diester and DNA Hydrolysis by a Multivalent, Nanoparticle-Based Catalyst

(2008) Renato Bonomi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Artificial restriction DNA cutter for site-selective scission of double-stranded DNA with tunable scission site and specificity

(2008) Makoto Komiyama et al.   Nature Protocols

Synthesis, structure and nuclease activity of copper complexes of disubstituted 2,2′-bipyridine ligands bearing ammonium groups

(2008) Ji-Hui Li et al.   POLYHEDRON