标题
Regulation of energy metabolism in the growth plate and osteoarthritic chondrocytes
作者
关键词
Osteoarthritis, Epiphyseal growth plate, Articular cartilage, Glycolysis, Oxidative phosphorylation, Regulation of energy metabolism
出版物
RHEUMATOLOGY INTERNATIONAL
Volume -, Issue -, Pages -
出版商
Springer Nature
发表日期
2018-07-17
DOI
10.1007/s00296-018-4103-4
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Pyruvate Kinase M2 Modulates the Glycolysis of Chondrocyte and Extracellular Matrix in Osteoarthritis
- (2018) Xiaobo Yang et al. DNA AND CELL BIOLOGY
- Blocking PI3K/AKT signaling inhibits bone sclerosis in subchondral bone and attenuates post-traumatic osteoarthritis
- (2018) Chuangxin Lin et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Osteoarthritis, cerebrovascular dysfunction and the common denominator of inflammation: a narrative review
- (2018) B.K. Al-Khazraji et al. OSTEOARTHRITIS AND CARTILAGE
- Glucose adsorption to chitosan membranes increases proliferation of human chondrocyte via mammalian target of rapamycin complex 1 and sterol regulatory element-binding protein-1 signaling
- (2017) Shun-Fu Chang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Signaling pathways effecting crosstalk between cartilage and adjacent tissues
- (2017) Christa Maes SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Regulated in Development and DNA Damage Response 1 Deficiency Impairs Autophagy and Mitochondrial Biogenesis in Articular Cartilage and Increases the Severity of Experimental Osteoarthritis
- (2017) Oscar Alvarez-Garcia et al. Arthritis & Rheumatology
- AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice
- (2017) Sheng Zhou et al. Scientific Reports
- PFKFB3 modulates glycolytic metabolism and alleviates endoplasmic reticulum stress in human osteoarthritis cartilage
- (2016) Jining Qu et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Berberine promotes proliferation of sodium nitroprusside-stimulated rat chondrocytes and osteoarthritic rat cartilage via Wnt/β-catenin pathway
- (2016) Yan Zhou et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Hypoxia-inducible factor-2α induces expression of type X collagen and matrix metalloproteinases 13 in osteoarthritic meniscal cells
- (2016) Shinya Ishizuka et al. INFLAMMATION RESEARCH
- Effect of glucosamine on expression of type II collagen, matrix metalloproteinase and sirtuin genes in a human chondrocyte cell line
- (2016) Mamoru Igarashi et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Inhibition of vascular endothelial growth factor with shRNA in chondrocytes ameliorates osteoarthritis
- (2016) Xufang Zhang et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Emerging role of metabolic signaling in synovial joint remodeling and osteoarthritis
- (2016) Ronald K. June et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Expression of hypoxia-inducible factor-1α in synovial fluid and articular cartilage is associated with disease severity in knee osteoarthritis
- (2016) Liming Qing et al. Experimental and Therapeutic Medicine
- mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation
- (2016) Bo Yan et al. Nature Communications
- Review: Metabolic Regulation of Inflammation in Osteoarthritis
- (2016) Francis Berenbaum et al. Arthritis & Rheumatology
- A novel fibroblast growth factor receptor 1 inhibitor protects against cartilage degradation in a murine model of osteoarthritis
- (2016) Wei Xu et al. Scientific Reports
- Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Regulates Chondrocyte Differentiation and Secondary Ossification in Mice
- (2016) Shaohong Cheng et al. Scientific Reports
- PPARγ deficiency results in severe, accelerated osteoarthritis associated with aberrant mTOR signalling in the articular cartilage
- (2015) Faezeh Vasheghani et al. ANNALS OF THE RHEUMATIC DISEASES
- Inhibition of hedgehog signal pathway by cyclopamine attenuates inflammation and articular cartilage damage in rats with adjuvant-induced arthritis
- (2015) Rong Li et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Changes in peripheral blood immune cell composition in osteoarthritis
- (2015) F. Ponchel et al. OSTEOARTHRITIS AND CARTILAGE
- Targeting the Hedgehog signaling pathway in cancer: beyond Smoothened
- (2015) Annelies Gonnissen et al. Oncotarget
- Overexpression of Sirtuin 6 suppresses cellular senescence and NF-κB mediated inflammatory responses in osteoarthritis development
- (2015) Yaosen Wu et al. Scientific Reports
- Low-Grade Inflammation in Symptomatic Knee Osteoarthritis: Prognostic Value of Inflammatory Plasma Lipids and Peripheral Blood Leukocyte Biomarkers
- (2015) Mukundan Attur et al. Arthritis & Rheumatology
- Mitochondrial Biogenesis Is Impaired in Osteoarthritis Chondrocytes but Reversible via Peroxisome Proliferator-Activated Receptor γ Coactivator 1α
- (2015) Yun Wang et al. Arthritis & Rheumatology
- Cartilage-specific deletion of mTOR upregulates autophagy and protects mice from osteoarthritis
- (2014) Yue Zhang et al. ANNALS OF THE RHEUMATIC DISEASES
- Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth
- (2014) Laura Di Magno et al. CELL CYCLE
- Indian Hedgehog, a critical modulator in osteoarthritis, could be a potential therapeutic target for attenuating cartilage degeneration disease
- (2014) Jingming Zhou et al. CONNECTIVE TISSUE RESEARCH
- mTORC1 signaling controls mammalian skeletal growth through stimulation of protein synthesis
- (2014) Jianquan Chen et al. DEVELOPMENT
- Association between hypoxia-inducible factor-1a levels in serum and synovial fluid with the radiographic severity of knee osteoarthritis
- (2014) H. Chu et al. GENETICS AND MOLECULAR RESEARCH
- Ral and Rheb GTPase Activating Proteins Integrate mTOR and GTPase Signaling in Aging, Autophagy, and Tumor Cell Invasion
- (2014) Timothy D. Martin et al. MOLECULAR CELL
- Emerging regulators of the inflammatory process in osteoarthritis
- (2014) Ru Liu-Bryan et al. Nature Reviews Rheumatology
- HIF-1α and HIF-2α are critically involved in hypoxia-induced lipid accumulation in hepatocytes through reducing PGC-1α-mediated fatty acid β-oxidation
- (2014) Yanlong Liu et al. TOXICOLOGY LETTERS
- Expression and function of visfatin (Nampt), an adipokine-enzyme involved in inflammatory pathways of osteoarthritis
- (2014) Marie-Charlotte Laiguillon et al. ARTHRITIS RESEARCH & THERAPY
- An Overview of MYC and Its Interactome
- (2014) M. Conacci-Sorrell et al. Cold Spring Harbor Perspectives in Medicine
- Disruption of Sirt1 in chondrocytes causes accelerated progression of osteoarthritis under mechanical stress and during ageing in mice
- (2013) Tokio Matsuzaki et al. ANNALS OF THE RHEUMATIC DISEASES
- NAMPT (visfatin), a direct target of hypoxia-inducible factor-2α, is an essential catabolic regulator of osteoarthritis
- (2013) Siyoung Yang et al. ANNALS OF THE RHEUMATIC DISEASES
- Turn up the power - pharmacological activation of mitochondrial biogenesis in mouse models
- (2013) J C Komen et al. BRITISH JOURNAL OF PHARMACOLOGY
- Towards elucidating the role of SirT1 in osteoarthritis
- (2013) Mona Dvir-Ginzberg Frontiers in Bioscience-Landmark
- Regulation of cellular metabolism: programming and maintaining metabolic homeostasis
- (2013) David F. Wilson JOURNAL OF APPLIED PHYSIOLOGY
- Do sirtuins promote mammalian longevity?: A Critical review on its relevance to the longevity effect induced by calorie restriction
- (2013) Seongjoon Park et al. MOLECULES AND CELLS
- Multiple phases of chondrocyte enlargement underlie differences in skeletal proportions
- (2013) Kimberly L. Cooper et al. NATURE
- Metabolism in physiological cell proliferation and differentiation
- (2013) Michalis Agathocleous et al. TRENDS IN CELL BIOLOGY
- Hypoxia promotes redifferentiation and suppresses markers of hypertrophy and degeneration in both healthy and osteoarthritic chondrocytes
- (2013) Brandon D Markway et al. ARTHRITIS RESEARCH & THERAPY
- Sirt6 regulates postnatal growth plate differentiation and proliferation via Ihh signaling
- (2013) Jinying Piao et al. Scientific Reports
- Increased apoptotic chondrocytes in articular cartilage from adult heterozygous SirT1 mice
- (2012) Odile Gabay et al. ANNALS OF THE RHEUMATIC DISEASES
- Sirtuin 1 enzymatic activity is required for cartilage homeostasis in vivo in a mouse model
- (2012) Odile Gabay et al. ARTHRITIS AND RHEUMATISM
- Hypoxia-Inducible Factors in Physiology and Medicine
- (2012) Gregg L. Semenza CELL
- Vertical inhibition of the PI3K/Akt/mTOR pathway for the treatment of osteoarthritis
- (2012) Jiezhong Chen et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Metabolic differentiation in the embryonic retina
- (2012) Michalis Agathocleous et al. NATURE CELL BIOLOGY
- Sirtuins as regulators of metabolism and healthspan
- (2012) Riekelt H. Houtkooper et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- SIRT1, a class III histone deacetylase, regulates TNF-α-induced inflammation in human chondrocytes
- (2012) M.-H. Moon et al. OSTEOARTHRITIS AND CARTILAGE
- Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)
- (2012) F. Berenbaum OSTEOARTHRITIS AND CARTILAGE
- AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network
- (2011) Antero Salminen et al. AGEING RESEARCH REVIEWS
- Increased interleukin-1β gene expression in peripheral blood leukocytes is associated with increased pain and predicts risk for progression of symptomatic knee osteoarthritis
- (2011) Mukundan Attur et al. ARTHRITIS AND RHEUMATISM
- Chondrocyte AMP-activated protein kinase activity suppresses matrix degradation responses to proinflammatory cytokines interleukin-1β and tumor necrosis factor α
- (2011) Robert Terkeltaub et al. ARTHRITIS AND RHEUMATISM
- Induction of the Mitochondrial NDUFA4L2 Protein by HIF-1α Decreases Oxygen Consumption by Inhibiting Complex I Activity
- (2011) Daniel Tello et al. Cell Metabolism
- The Effects of Adipokines on Cartilage and Meniscus Catabolism
- (2011) Amy L. McNulty et al. CONNECTIVE TISSUE RESEARCH
- Are we moving in the right direction with osteoarthritis drug discovery?
- (2011) Jan Bondeson EXPERT OPINION ON THERAPEUTIC TARGETS
- Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance
- (2011) Rui-Hong Wang et al. JOURNAL OF CLINICAL INVESTIGATION
- HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells
- (2011) Lewis Z. Shi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Aquaporin-1: a potential membrane channel for facilitating the adaptability of rabbit nucleus pulposus cells to an extracellular matrix environment
- (2011) Feng Wang et al. JOURNAL OF ORTHOPAEDIC SCIENCE
- The role of mitochondria in osteoarthritis
- (2011) Francisco J. Blanco et al. Nature Reviews Rheumatology
- Expression and function of the insulin receptor in normal and osteoarthritic human chondrocytes: modulation of anabolic gene expression, glucose transport and GLUT-1 content by insulin
- (2011) S.C. Rosa et al. OSTEOARTHRITIS AND CARTILAGE
- Sequential and Coordinated Actions of c-Myc and N-Myc Control Appendicular Skeletal Development
- (2011) Zi-Qiang Zhou et al. PLoS One
- TNFα-mediated apoptosis in human osteoarthritic chondrocytes sensitized by PI3K-NF-κB inhibitor, not mTOR inhibitor
- (2011) Deling Li et al. RHEUMATOLOGY INTERNATIONAL
- Increased synovial fluid visfatin is positively linked to cartilage degradation biomarkers in osteoarthritis
- (2011) Yuanhui Duan et al. RHEUMATOLOGY INTERNATIONAL
- A Central Role for Hypoxic Signaling in Cartilage, Bone, and Hematopoiesis
- (2011) Erinn B. Rankin et al. Current Osteoporosis Reports
- Superoxide dismutase downregulation in osteoarthritis progression and end-stage disease
- (2010) J. L. Scott et al. ANNALS OF THE RHEUMATIC DISEASES
- Hypoxia, HIFs and bone development
- (2010) Elisa Araldi et al. BONE
- Is Cartilage Matrix Breakdown an Appropriate Therapeutic Target in Osteoarthritis – Insights from Studies of Aggrecan and Collagen Proteolysis?
- (2010) Christopher B. Little et al. CURRENT DRUG TARGETS
- The evolving role of obesity in knee osteoarthritis
- (2010) MaryFran R Sowers et al. CURRENT OPINION IN RHEUMATOLOGY
- Review: Energy regulation and neuroendocrine-immune control in chronic inflammatory diseases
- (2010) R. H. Straub et al. JOURNAL OF INTERNAL MEDICINE
- mTOR: from growth signal integration to cancer, diabetes and ageing
- (2010) Roberto Zoncu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- AMP-Activated Protein Kinase-Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol
- (2009) J.-H. Um et al. DIABETES
- Chondrocyte autophagy is stimulated by HIF-1 dependent AMPK activation and mTOR suppression
- (2009) Jolene Bohensky et al. PEDIATRIC NEPHROLOGY
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- PTEN deficiency causes dyschondroplasia in mice by enhanced hypoxia-inducible factor 1 signaling and endoplasmic reticulum stress
- (2008) G. Yang et al. DEVELOPMENT
- mTOR signaling contributes to chondrocyte differentiation
- (2008) Chanika Phornphutkul et al. DEVELOPMENTAL DYNAMICS
- Adipokines in osteoarthritis: friends or foes of cartilage homeostasis?
- (2008) Pascale Pottie Gegout et al. JOINT BONE SPINE
- Osteoarthritis and obesity: Experimental models
- (2008) Odile Gabay et al. JOINT BONE SPINE
- Regulation of Cartilage-specific Gene Expression in Human Chondrocytes by SirT1 and Nicotinamide Phosphoribosyltransferase
- (2008) Mona Dvir-Ginzberg et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia
- (2008) Huafeng Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
- (2008) Dana M. Gwinn et al. MOLECULAR CELL
- TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
- (2008) Liang Zhou et al. NATURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now