Low-Grade Inflammation in Symptomatic Knee Osteoarthritis: Prognostic Value of Inflammatory Plasma Lipids and Peripheral Blood Leukocyte Biomarkers

OA phenotypes, rather than disease stage, drive structural progression – identification of structural progressors from 2 phase III randomized clinical studies with symptomatic knee OA

(2015) M.A. Karsdal et al.   OSTEOARTHRITIS AND CARTILAGE

Soluble Macrophage Biomarkers Indicate Inflammatory Phenotypes in Patients With Knee Osteoarthritis

(2015) Hikmat N. Daghestani et al.   Arthritis & Rheumatology

Prostaglandin E2 Exerts Catabolic Effects in Osteoarthritis Cartilage: Evidence for Signaling via the EP4 Receptor

(2014) M. Attur et al.   JOURNAL OF IMMUNOLOGY

Synovitis in Knee Osteoarthritis Assessed by Contrast-enhanced Magnetic Resonance Imaging (MRI) is Associated with Radiographic Tibiofemoral Osteoarthritis and MRI-detected Widespread Cartilage Damage: The MOST Study

(2014) A. Guermazi et al.   JOURNAL OF RHEUMATOLOGY

Body mass index and knee osteoarthritis risk: A dose-response meta-analysis

(2014) Zhen-Yu Zhou et al.   Obesity

Genes expressed in blood link osteoarthritis with apoptotic pathways

(2013) Yolande F M Ramos et al.   ANNALS OF THE RHEUMATIC DISEASES

Value of biomarkers in osteoarthritis: current status and perspectives

(2013) M Lotz et al.   ANNALS OF THE RHEUMATIC DISEASES

How to define responders in osteoarthritis

(2013) Cyrus Cooper et al.   CURRENT MEDICAL RESEARCH AND OPINION

IL-1 receptor antagonist gene as a predictive biomarker of progression of knee osteoarthritis in a population cohort

(2013) X. Wu et al.   OSTEOARTHRITIS AND CARTILAGE

A role for PACE4 in osteoarthritis pain: evidence from human genetic association and null mutant phenotype

(2012) Anne-Marie Malfait et al.   ANNALS OF THE RHEUMATIC DISEASES

Plasma and synovial fluid connective tissue growth factor levels are correlated with disease severity in patients with knee osteoarthritis

(2012) Sittisak Honsawek et al.   BIOMARKERS

Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)

(2012) F. Berenbaum   OSTEOARTHRITIS AND CARTILAGE

Transcriptome modification of white blood cells after dietary administration of curcumin and non-steroidal anti-inflammatory drug in osteoarthritic affected dogs

(2012) M. Colitti et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Plasma proteins present in osteoarthritic synovial fluid can stimulate cytokine production via Toll-like receptor 4

(2012) Dong Sohn et al.   ARTHRITIS RESEARCH & THERAPY

Increased interleukin-1β gene expression in peripheral blood leukocytes is associated with increased pain and predicts risk for progression of symptomatic knee osteoarthritis

(2011) Mukundan Attur et al.   ARTHRITIS AND RHEUMATISM

Quantitative magnetic resonance imaging evidence of synovial proliferation is associated with radiographic severity of knee osteoarthritis

(2011) Svetlana Krasnokutsky et al.   ARTHRITIS AND RHEUMATISM

Body mass index and alignment and their interaction as risk factors for progression of knees with radiographic signs of osteoarthritis

(2011) E. Yusuf et al.   OSTEOARTHRITIS AND CARTILAGE

Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation

(2011) Anna E. Denoble et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of Matrix Metalloproteinase-3 and -13 Synthesis Induced by IL-1  in Chondrocytes from Mice Lacking Microsomal Prostaglandin E Synthase-1

(2010) M. Gosset et al.   JOURNAL OF IMMUNOLOGY

Low innate production of interleukin-1β and interleukin-6 is associated with the absence of osteoarthritis in old age

(2010) R.J. Goekoop et al.   OSTEOARTHRITIS AND CARTILAGE

Circulating levels of IL-6 and TNF-α are associated with knee radiographic osteoarthritis and knee cartilage loss in older adults

(2010) O. Stannus et al.   OSTEOARTHRITIS AND CARTILAGE

Is obesity a risk factor for progressive radiographic knee osteoarthritis?

(2009) J. Niu et al.   ARTHRITIS AND RHEUMATISM

12/15-Lipoxygenase Counteracts Inflammation and Tissue Damage in Arthritis

(2009) G. Kronke et al.   JOURNAL OF IMMUNOLOGY

Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids

(2009) Karina Roxana Gheorghe et al.   ARTHRITIS RESEARCH & THERAPY

Progressive increase in body mass index is not associated with a progressive increase in joint space narrowing in obese women with osteoarthritis of the knee

(2008) M-P H. Le Graverand et al.   ANNALS OF THE RHEUMATIC DISEASES

The synovitis of "non-inflammatory" orthopaedic arthropathies: a quantitative histological and immunohistochemical analysis

(2008) F Pessler et al.   ANNALS OF THE RHEUMATIC DISEASES

Joint space narrowing and Kellgren–Lawrence progression in knee osteoarthritis: an analytic literature synthesis

(2008) P.S. Emrani et al.   OSTEOARTHRITIS AND CARTILAGE

The chondroprotective effect of selective COX-2 inhibition in osteoarthritis: ex vivo evaluation of human cartilage tissue after in vivo treatment

(2008) T.N. de Boer et al.   OSTEOARTHRITIS AND CARTILAGE