PFKFB3 modulates glycolytic metabolism and alleviates endoplasmic reticulum stress in human osteoarthritis cartilage

Endoplasmic reticulum stress-induced apoptosis contributes to articular cartilage degeneration via C/EBP homologous protein

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Combination therapy targeting ectopic ATP synthase and 26S proteasome induces ER stress in breast cancer cells

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Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway

(2014) Takehiro Yamamoto et al.   Nature Communications

PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli

(2013) Laura Novellasdemunt et al.   BIOCHEMICAL JOURNAL

ATF6 upregulates XBP1S and inhibits ER stress-mediated apoptosis in osteoarthritis cartilage

(2013) Feng-Jin Guo et al.   CELLULAR SIGNALLING

Osteoarthritis

(2013) Sujata Sovani et al.   Orthopaedic Nursing

Impaired glycolytic metabolism causes chondrocyte hypertrophy-like changes via promotion of phospho-Smad1/5/8 translocation into nucleus

(2013) T. Nishida et al.   OSTEOARTHRITIS AND CARTILAGE

Control of vessel sprouting by genetic and metabolic determinants

(2013) Guy Eelen et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

MTT assay for cell viability: Intracellular localization of the formazan product is in lipid droplets

(2012) Juan C. Stockert et al.   ACTA HISTOCHEMICA

Metabolic syndrome meets osteoarthritis

(2012) Qi Zhuo et al.   Nature Reviews Rheumatology

Activation of AMP-Activated Protein Kinase Inhibits Albumin-Induced Endoplasmic Reticulum Stress and Apoptosis through Inhibition of Reactive Oxygen Species

(2012) Eun Kyoung Lee et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

Enhanced apoptotic and reduced protective response in chondrocytes following endoplasmic reticulum stress in osteoarthritic cartilage

(2011) Koji Takada et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Proteomic changes in articular cartilage of human endemic osteoarthritis in China

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Pre-treatment with capsaicin in a rat osteoarthritis model reduces the symptoms of pain and bone damage induced by monosodium iodoacetate

(2010) Karel-Martijn Kalff et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Disruption of Inducible 6-Phosphofructo-2-kinase Ameliorates Diet-induced Adiposity but Exacerbates Systemic Insulin Resistance and Adipose Tissue Inflammatory Response

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