The mechanistic target of rapamycin (mTOR) and the silent mating-type information regulation 2 homolog 1 (SIRT1): oversight for neurodegenerative disorders

Ketogenic diet attenuates neuronal injury via autophagy and mitochondrial pathways in pentylenetetrazol-kindled seizures

(2018) Bao-Hui Wang et al.   BRAIN RESEARCH

Forkhead Transcription Factors: Formulating a FOXO Target for Cognitive Loss

(2018) Kenneth Maiese   CURRENT NEUROVASCULAR RESEARCH

Sirt1: A Guardian of the Development of Diabetic Retinopathy

(2018) Manish Mishra et al.   DIABETES

MECHANISMS IN ENDOCRINOLOGY: SGLT2 inhibitors: clinical benefits by restoration of normal diurnal metabolism?

(2018) Russell L Esterline et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Can Co-Activation of Nrf2 and Neurotrophic Signaling Pathway Slow Alzheimer’s Disease?

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Alterations of Clock Gene RNA Expression in Brain Regions of a Triple Transgenic Model of Alzheimer’s Disease

(2017) Francesco Bellanti et al.   JOURNAL OF ALZHEIMERS DISEASE

Construction of competitive endogenous RNA network reveals regulatory role of long non-coding RNAs in type 2 diabetes mellitus

(2017) Zijing Lin et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Therapeutic potency of mTOR signaling pharmacological inhibitors in the treatment of proinflammatory diseases, current status, and perspectives

(2017) Arash Soltani et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Crocin Inhibits Oxidative Stress and Pro-inflammatory Response of Microglial Cells Associated with Diabetic Retinopathy Through the Activation of PI3K/Akt Signaling Pathway

(2017) Xinguang Yang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Acute high-caffeine exposure increases autophagic flux and reduces protein synthesis in C2C12 skeletal myotubes

(2017) M. A. Hughes et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Axonal Degeneration in Retinal Ganglion Cells Is Associated with a Membrane Polarity-Sensitive Redox Process

(2017) Mohammadali Almasieh et al.   JOURNAL OF NEUROSCIENCE

Selenomethionine Mitigates Cognitive Decline by Targeting Both Tau Hyperphosphorylation and Autophagic Clearance in an Alzheimer's Disease Mouse Model

(2017) Zhong-Hao Zhang et al.   JOURNAL OF NEUROSCIENCE

Temporal changes in mammalian target of rapamycin (mTOR) and phosphorylated-mTOR expressions in the hippocampal CA1 region of rat with vascular dementia

(2017) Jin-A Park et al.   Journal of Veterinary Science

Overexpression of miR‑185 inhibits autophagy and apoptosis of dopaminergic neurons by regulating the AMPK/mTOR signaling pathway in Parkinson's disease

(2017) Zhi Wen et al.   Molecular Medicine Reports

Therapeutic potential of autophagy-enhancing agents in Parkinson’s disease

(2017) Tim E. Moors et al.   Molecular Neurodegeneration

Identification of Novel Vacuolin-1 Analogues as Autophagy Inhibitors by Virtual Drug Screening and Chemical Synthesis

(2017) Chang Chen et al.   MOLECULES

Nimodipine activates neuroprotective signaling events and inactivates autophages in the VCID rat hippocampus

(2017) Ming Hu et al.   NEUROLOGICAL RESEARCH

Caveolin1/protein arginine methyltransferase1/sirtuin1 axis as a potential target against endothelial dysfunction

(2017) Soniya Charles et al.   PHARMACOLOGICAL RESEARCH

Retinoic acid ameliorates high-fat diet-induced liver steatosis through sirt1

(2017) Chao Geng et al.   Science China-Life Sciences

Erythropoietin activates SIRT1 to protect human cardiomyocytes against doxorubicin-induced mitochondrial dysfunction and toxicity

(2017) Lan Cui et al.   TOXICOLOGY LETTERS

Hormetic effect of panaxatriol saponins confers neuroprotection in PC12 cells and zebrafish through PI3K/AKT/mTOR and AMPK/SIRT1/FOXO3 pathways

(2017) Chao Zhang et al.   Scientific Reports

The Effect of Pyrroloquinoline Quinone on the Expression of WISP1 in Traumatic Brain Injury

(2017) Yongqi Ye et al.   Stem Cells International

Dammarane Sapogenins Ameliorates Neurocognitive Functional Impairment Induced by Simulated Long-Duration Spaceflight

(2017) Xiaorui Wu et al.   Frontiers in Pharmacology

Anti-aging pharmacology: Promises and pitfalls

(2016) Alexander M. Vaiserman et al.   AGEING RESEARCH REVIEWS

Injection of Aβ1-40 into hippocampus induced cognitive lesion associated with neuronal apoptosis and multiple gene expressions in the tree shrew

(2016) Na Lin et al.   APOPTOSIS

Reduced risk of apoptosis: mechanisms of stress responses

(2016) Irina Milisav et al.   APOPTOSIS

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Autophagy in Diabetic Retinopathy

(2016) Michelino Di Rosa et al.   Current Neuropharmacology

Erythropoietin and mTOR: A “One-Two Punch” for Aging-Related Disorders Accompanied by Enhanced Life Expectancy

(2016) Kenneth Maiese   CURRENT NEUROVASCULAR RESEARCH

Histone Deacetylase SIRT1 Controls Proliferation, Circadian Rhythm, and Lipid Metabolism during Liver Regeneration in Mice

(2016) Marina Maria Bellet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tribbles Pseudokinase 3 Induces Both Apoptosis and Autophagy in Amyloid-β-induced Neuronal Death

(2016) Suraiya Saleem et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Everolimus (RAD001) ameliorates vascular cognitive impairment by regulating microglial function via the mTORC1 signaling pathway

(2016) Li Chen et al.   JOURNAL OF NEUROIMMUNOLOGY

Long-term treatment with nicotinamide induces glucose intolerance and skeletal muscle lipotoxicity in normal chow-fed mice: compared to diet-induced obesity

(2016) Zhengtang Qi et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

CHOP Contributes to, But Is Not the Only Mediator of, IAPP Induced β-Cell Apoptosis

(2016) T. Gurlo et al.   MOLECULAR ENDOCRINOLOGY

Effect and mechanism of fuzhisan and donepezil on the sirtuin 1 pathway and amyloid precursor protein metabolism in PC12 cells

(2016) PENG GUO et al.   Molecular Medicine Reports

The mTOR signalling cascade: paving new roads to cure neurological disease

(2016) Peter B. Crino   Nature Reviews Neurology

Novel nervous and multi-system regenerative therapeutic strategies for diabetes mellitus with mTOR

(2016) Kenneth Maiese   Neural Regeneration Research

Beneficial effects of omega-3 and vitamin E coadministration on gene expression of SIRT1 and PGC1α and serum antioxidant enzymes in patients with coronary artery disease

(2016) S. Saboori et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Chitotriosidase: A New Inflammatory Marker in Diabetic Complications

(2016) Michelino Di Rosa et al.   PATHOBIOLOGY

Sirt1 is essential for resveratrol enhancement of hypoxia-induced autophagy in the type 2 diabetic nephropathy rat

(2016) Liqun Ma et al.   PATHOLOGY RESEARCH AND PRACTICE

Carnosine ameliorates cognitive deficits in streptozotocin-induced diabetic rats: Possible involved mechanisms

(2016) Siamak Ahshin-Majd et al.   PEPTIDES

NAD+ as the Link Between Oxidative Stress, Inflammation, Caloric Restriction, Exercise, DNA Repair, Longevity, and Health Span

(2016) Borut Poljsak et al.   REJUVENATION RESEARCH

4-Nonylphenol induces apoptosis, autophagy and necrosis in Sertoli cells: Involvement of ROS-mediated AMPK/AKT-mTOR and JNK pathways

(2016) Peng Duan et al.   TOXICOLOGY

Sirtuin 1 activation protects against early brain injury after experimental subarachnoid hemorrhage in rats

(2016) Xiang-Sheng Zhang et al.   Cell Death & Disease

Sulforaphane protects against rotenone-induced neurotoxicity in vivo: Involvement of the mTOR, Nrf2 and autophagy pathways

(2016) Qian Zhou et al.   Scientific Reports

Neuroprotective effects of the anticancer drug NVP-BEZ235 (dactolisib) on amyloid-β 1–42 induced neurotoxicity and memory impairment

(2016) Paula Maria Quaglio Bellozi et al.   Scientific Reports

Prevention of β-amyloid degeneration of microglia by erythropoietin depends on Wnt1, the PI 3-K/mTOR pathway, Bad, and Bcl-xL

(2016) Yan Chen Shang et al.   Aging-US

Enhancing Beta-Catenin Activity via GSK3beta Inhibition Protects PC12 Cells against Rotenone Toxicity through Nurr1 Induction

(2016) Limin Zhang et al.   PLoS One

The SIRT1 inhibitor, nicotinamide, inhibits hepatitis B virus replication in vitro and in vivo

(2015) Wan-Yu Li et al.   ARCHIVES OF VIROLOGY

Effect of caloric restriction on the SIRT1/mTOR signaling pathways in senile mice

(2015) Lina Ma et al.   BRAIN RESEARCH BULLETIN

Targeting molecules to medicine with mTOR, autophagy and neurodegenerative disorders

(2015) Kenneth Maiese   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

FoxO Transcription Factors and Regenerative Pathways in Diabetes Mellitus

(2015) Kenneth Maiese   CURRENT NEUROVASCULAR RESEARCH

Programming Apoptosis and Autophagy with Novel Approaches for Diabetes Mellitus

(2015) Kenneth Maiese   CURRENT NEUROVASCULAR RESEARCH

mTOR inhibition by rapamycin protects against deltamethrin-induced apoptosis in PC12 Cells

(2015) Yun Sun Park et al.   ENVIRONMENTAL TOXICOLOGY

Icariin protects against intestinal ischemia–reperfusion injury

(2015) Feng Zhang et al.   JOURNAL OF SURGICAL RESEARCH

Aβ peptide secretion is reduced by Radix Polygalae-induced autophagy via activation of the AMPK/mTOR pathway

(2015) HUAN ZHAO et al.   Molecular Medicine Reports

The Neuroprotective Effect of Erythropoietin on Rotenone-Induced Neurotoxicity in SH-SY5Y Cells Through the Induction of Autophagy

(2015) Wooyoung Jang et al.   MOLECULAR NEUROBIOLOGY

Quercetin is a potent anti-atherosclerotic compound by activation of SIRT1 signaling under oxLDL stimulation

(2015) Ching-Hsia Hung et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Ameliorating the Effect of Astragaloside IV on Learning and Memory Deficit after Chronic Cerebral Hypoperfusion in Rats

(2015) Sooyong Kim et al.   MOLECULES

Novel applications of trophic factors, Wnt and WISP for neuronal repair and regeneration in metabolic disease

(2015) Kenneth Maiese   Neural Regeneration Research

Erythropoietin Attenuates Advanced Glycation Endproducts-Induced Toxicity of Schwann Cells In Vitro

(2015) Ting Yu et al.   NEUROCHEMICAL RESEARCH

Reinstating Aberrant mTORC1 Activity in Huntington’s Disease Mice Improves Disease Phenotypes

(2015) John H. Lee et al.   NEURON

Obesity and hyperglycemia lead to impaired post-ischemic recovery after permanent ischemia in mice

(2015) Jatin Tulsulkar et al.   Obesity

New Insights for Oxidative Stress and Diabetes Mellitus

(2015) Kenneth Maiese   Oxidative Medicine and Cellular Longevity

Increased Oxidative and Nitrative Stress Accelerates Aging of the Retinal Vasculature in the Diabetic Retina

(2015) Folami Lamoke et al.   PLoS One

Aging and Autophagic Function Influences the Progressive Decline of Adult Drosophila Behaviors

(2015) Eric P. Ratliff et al.   PLoS One

FoxO Proteins in the Nervous System

(2015) Kenneth Maiese   Analytical Cellular Pathology

MicroRNA-212 negatively regulates starvation induced autophagy in prostate cancer cells by inhibiting SIRT1 and is a modulator of angiogenesis and cellular senescence

(2015) Malathi Ramalinga et al.   Oncotarget

Fasting activates macroautophagy in neurons of Alzheimer’s disease mouse model but is insufficient to degrade amyloid-beta

(2015) Xigui Chen et al.   Scientific Reports

Tet1-mediated DNA demethylation regulates neuronal cell death induced by oxidative stress

(2015) Yong-Juan Xin et al.   Scientific Reports

SIRT1 and stem cells: In the forefront with cardiovascular disease, neurodegeneration and cancer

(2015) Kenneth Maiese   World Journal of Stem Cells

Evidence for Immune Response, Axonal Dysfunction and Reduced Endocytosis in the Substantia Nigra in Early Stage Parkinson’s Disease

(2015) Anke A. Dijkstra et al.   PLoS One

β-Hydroxy-β-Methylbutyrate (HMB) Promotes Neurite Outgrowth in Neuro2a Cells

(2015) Rafael Salto et al.   PLoS One

Dietary restriction involves NAD+-dependent mechanisms and a shift toward oxidative metabolism

(2014) Natalie Moroz et al.   AGING CELL

Taking aim at Alzheimer's disease through the mammalian target of rapamycin

(2014) Kenneth Maiese   ANNALS OF MEDICINE

Activation of SIRT1 by curcumin blocks the neurotoxicity of amyloid-β25–35 in rat cortical neurons

(2014) Qinru Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

High Glucose Condition Induces Autophagy in Endothelial Progenitor Cells Contributing to Angiogenic Impairment

(2014) Kyeong-A Kim et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Genetic polymorphisms at SIRT1 and FOXO1 are associated with carotid atherosclerosis in the SAPHIR cohort

(2014) Lyudmyla Kedenko et al.   BMC Medical Genetics

ADSC Therapy in Neurodegenerative Disorders

(2014) Tzu-Min Chan et al.   CELL TRANSPLANTATION

SIRT1 in cardiovascular aging

(2014) Xin-Yuan Luo et al.   CLINICA CHIMICA ACTA

μ-Opioid Receptor Attenuates AβOligomers-Induced Neurotoxicity Through mTOR Signaling

(2014) Yan Wang et al.   CNS Neuroscience & Therapeutics

Cutting through the Complexities of mTOR for the Treatment of Stroke

(2014) Kenneth Maiese   CURRENT NEUROVASCULAR RESEARCH

Key network approach reveals new insight into Alzheimer's disease

(2014) Jan K. Schluesener et al.   IET Systems Biology

Role of SIRT1 in autoimmune demyelination and neurodegeneration

(2014) Alvaro Martin et al.   IMMUNOLOGIC RESEARCH

Simvastatin attenuates TNF-α-induced apoptosis in endothelial progenitor cells via the upregulation of SIRT1

(2014) GANG DU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

A Potential Treatment of Nonalcoholic Fatty Liver Disease with SIRT1 Activators

(2014)   Journal of Gastrointestinal and Liver Diseases

Longitudinal follow-up of autophagy and inflammation in brain of APPswePS1dE9 transgenic mice

(2014) Arnaud François et al.   Journal of Neuroinflammation

mTor Is a Signaling Hub in Cell Survival: A Mass-Spectrometry-Based Proteomics Investigation

(2014) Zhi Tang et al.   JOURNAL OF PROTEOME RESEARCH

Delphinidin-3-glucoside protects human umbilical vein endothelial cells against oxidized low-density lipoprotein-induced injury by autophagy upregulation via the AMPK/SIRT1 signaling pathway

(2014) Xin Jin et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Driving neural regeneration through the mammalian target of rapamycin

(2014) Kenneth Maiese   Neural Regeneration Research

SIRT1 Positively Regulates Autophagy and Mitochondria Function in Embryonic Stem Cells Under Oxidative Stress

(2014) Xuan Ou et al.   STEM CELLS

The Antiproliferative and Apoptotic Effects of Sirtinol, a Sirtuin Inhibitor on Human Lung Cancer Cells by Modulating Akt/β-Catenin-Foxo3A Axis

(2014) Yao Fong et al.   TheScientificWorldJOURNAL

(R)-(+)-α-Lipoic acid protected NG108-15 cells against H2O2-induced cell death through PI3K-Akt/GSK-3β pathway and suppression of NF-κβ-cytokines

(2014) Abdul Kadir et al.   Drug Design Development and Therapy

SIRT1 Inhibition Affects Angiogenic Properties of Human MSCs

(2014) Botti Chiara et al.   Biomed Research International

FoxO Transcription Factors Support Oxidative Stress Resistance in Human Chondrocytes

(2014) Yukio Akasaki et al.   Arthritis & Rheumatology

EGB1212 Post-treatment Ameliorates Hippocampal CA1 Neuronal Death and Memory Impairment Induced by Transient Global Cerebral Ischemia/Reperfusion

(2013) Bo Yin et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Increased phosphorylation of mTOR is involved in remote ischemic preconditioning of hippocampus in mice

(2013) Fatemeh Zare Mehrjerdi et al.   BRAIN RESEARCH

Excitotoxic glutamate insults block autophagic flux in hippocampal neurons

(2013) Jacqueline R. Kulbe et al.   BRAIN RESEARCH

Metformin modulates hyperglycaemia-induced endothelial senescence and apoptosis through SIRT1

(2013) Gnanapragasam Arunachalam et al.   BRITISH JOURNAL OF PHARMACOLOGY

Tuberous Sclerosis Protein 2 (TSC2) Modulates CCN4 Cytoprotection During Apoptotic Amyloid Toxicity in Microglia

(2013) Yan Chen Shang et al.   CURRENT NEUROVASCULAR RESEARCH

Caloric restriction and aging stem cells: The stick and the carrot?

(2013) Gianluigi Mazzoccoli et al.   EXPERIMENTAL GERONTOLOGY

Involvement of interleukin-1β in the autophagic process of microglia: relevance to Alzheimer’s disease

(2013) Arnaud François et al.   Journal of Neuroinflammation

Arctigenin Effectively Ameliorates Memory Impairment in Alzheimer's Disease Model Mice Targeting Both  -Amyloid Production and Clearance

(2013) Z. Zhu et al.   JOURNAL OF NEUROSCIENCE

Poly(ADP-ribose) Polymerase 1 (PARP1) in Atherosclerosis: From Molecular Mechanisms to Therapeutic Implications

(2013) Suowen Xu et al.   MEDICINAL RESEARCH REVIEWS

Dysfunction of Endothelial Progenitor Cells from Smokers and Chronic Obstructive Pulmonary Disease Patients Due to Increased DNA Damage and Senescence

(2013) Koralia E. Paschalaki et al.   STEM CELLS

Nicotinamide-mediated inhibition of SIRT1 deacetylase is associated with the viability of cancer cells exposed to antitumor agents and apoptosis

(2013) TONG WANG et al.   Oncology Letters

Sirtuins: from metabolic regulation to brain aging

(2013) Wenzhen Duan   Frontiers in Aging Neuroscience

Mammalian target of rapamycin signaling in diabetic cardiovascular disease

(2012) Zhao Chong et al.   Cardiovascular Diabetology

Wnt1 Inducible Signaling Pathway Protein 1 (WISP1) Targets PRAS40 to Govern β-Amyloid Apoptotic Injury of Microglia

(2012) Yan Chen Shang et al.   CURRENT NEUROVASCULAR RESEARCH

Novel directions for diabetes mellitus drug discovery

(2012) Kenneth Maiese et al.   Expert Opinion on Drug Discovery

Targeting disease through novel pathways of apoptosis and autophagy

(2012) Kenneth Maiese et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

SIRT1: new avenues of discovery for disorders of oxidative stress

(2012) Zhao Zhong Chong et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Erythropoietin Modulates Autophagy Signaling in the Developing Rat Brain in an In Vivo Model of Oxygen-Toxicity

(2012) Ivo Bendix et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oxidant Stress and Signal Transduction in the Nervous System with the PI 3-K, Akt, and mTOR Cascade

(2012) Kenneth Maiese et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy in hypoxia-ischemia induced brain injury

(2012) Walter Balduini et al.   Journal of Maternal-Fetal & Neonatal Medicine

Activation of Wnt/β-catenin Pathway by Exogenous Wnt1 Protects SH-SY5Y Cells Against 6-Hydroxydopamine Toxicity

(2012) Lei Wei et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Neuroprotective properties of Loranthus parasiticus aqueous fraction against oxidative stress-induced damage in NG108-15 cells

(2012) Daniel Zin Hua Wong et al.   Journal of Natural Medicines

Regulation of mTOR Complex 2 Signaling in Neurofibromatosis 2-Deficient Target Cell Types

(2012) M. F. James et al.   MOLECULAR CANCER RESEARCH

Autophagy induced by resveratrol prevents human prion protein-mediated neurotoxicity

(2012) Jae-Kyo Jeong et al.   NEUROSCIENCE RESEARCH

Systemic Bisperoxovanadium Activates Akt/mTOR, Reduces Autophagy, and Enhances Recovery following Cervical Spinal Cord Injury

(2012) Chandler L. Walker et al.   PLoS One

Shedding new light on neurodegenerative diseases through the mammalian target of rapamycin

(2012) Zhao Zhong Chong et al.   PROGRESS IN NEUROBIOLOGY

mTOR: on target for novel therapeutic strategies in the nervous system

(2012) Kenneth Maiese et al.   TRENDS IN MOLECULAR MEDICINE

MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells

(2011) Giampietro Viola et al.   BIOCHEMICAL PHARMACOLOGY

mTORC1 and mTORC2 Regulate EMT, Motility, and Metastasis of Colorectal Cancer via RhoA and Rac1 Signaling Pathways

(2011) P. Gulhati et al.   CANCER RESEARCH

Erythropoietin Employs Cell Longevity Pathways of SIRT1 to Foster Endothelial Vascular Integrity During Oxidant Stress

(2011) Jinling Hou et al.   CURRENT NEUROVASCULAR RESEARCH

GADD34 mediates cytoprotective autophagy in mutant huntingtin expressing cells via the mTOR pathway

(2011) Alise Hyrskyluoto et al.   EXPERIMENTAL CELL RESEARCH

Multiple Site Acetylation of Rictor Stimulates Mammalian Target of Rapamycin Complex 2 (mTORC2)-dependent Phosphorylation of Akt Protein

(2011) Emily J. Glidden et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapamycin Promotes Autophagy and Reduces Neural Tissue Damage and Locomotor Impairment after Spinal Cord Injury in Mice

(2011) Akira Sekiguchi et al.   JOURNAL OF NEUROTRAUMA

The PI3K/Akt/mTOR pathway mediates retinal progenitor cell survival under hypoxic and superoxide stress

(2011) Karan P. Sanghera et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Mammalian Target of Rapamycin: Hitting the Bull's-Eye for Neurological Disorders

(2011) Zhao Zhong Chong et al.   Oxidative Medicine and Cellular Longevity

PTEN deletion prevents ischemic brain injury by activating the mTOR signaling pathway

(2010) G.D. Shi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Wnt1, FoxO3a, and NF-κB oversee microglial integrity and activation during oxidant stress

(2010) Yan Chen Shang et al.   CELLULAR SIGNALLING

Early Apoptotic Vascular Signaling is Determined by Sirt1 Through Nuclear Shuttling, Forkhead Trafficking, Bad, and Mitochondrial Caspase Activation

(2010) Jinling Hou et al.   CURRENT NEUROVASCULAR RESEARCH

The inhibitor of phagocytosis, O-phospho-l-serine, suppresses Müller glia proliferation and cone cell regeneration in the light-damaged zebrafish retina

(2010) Travis J. Bailey et al.   EXPERIMENTAL EYE RESEARCH

Oxidative stress: Biomarkers and novel therapeutic pathways

(2010) Kenneth Maiese et al.   EXPERIMENTAL GERONTOLOGY

Hydrogen peroxide inhibits mTOR signaling by activation of AMPKα leading to apoptosis of neuronal cells

(2010) Long Chen et al.   LABORATORY INVESTIGATION

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

IGF-I stimulates Rab7-RILP interaction during neuronal autophagy

(2010) Mona Bains et al.   NEUROSCIENCE LETTERS

FoxO3a Governs Early Microglial Proliferation and Employs Mitochondrial Depolarization with Caspase 3, 8, and 9 Cleavage During Oxidant Induced Apoptosis

(2009) Yan Shang et al.   CURRENT NEUROVASCULAR RESEARCH

A novel mTOR activating protein protects dopamine neurons against oxidative stress by repressing autophagy related cell death

(2009) Kyou-Chan Choi et al.   JOURNAL OF NEUROCHEMISTRY

Enhanced Tolerance against Early and Late Apoptotic Oxidative Stress in Mammalian Neurons through Nicotinamidase and Sirtuin Mediated Pathways

(2008) Zhao Chong et al.   CURRENT NEUROVASCULAR RESEARCH

Life Span Extension and Neuronal Cell Protection byDrosophilaNicotinamidase

(2008) Vitaly Balan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY