Increased Oxidative and Nitrative Stress Accelerates Aging of the Retinal Vasculature in the Diabetic Retina

NADPH oxidase NOX1 is involved in activation of protein kinase C and premature senescence in early stage diabetic kidney

(2015) Kai Zhu et al.   FREE RADICAL BIOLOGY AND MEDICINE

The SIRT1 activator SRT1720 reverses vascular endothelial dysfunction, excessive superoxide production, and inflammation with aging in mice

(2014) Lindsey B. Gano et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cellular senescence and the senescent secretory phenotype in age-related chronic diseases

(2014) Yi Zhu et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

MitomiRs in human inflamm-aging: A hypothesis involving miR-181a, miR-34a and miR-146a

(2014) Maria Rita Rippo et al.   EXPERIMENTAL GERONTOLOGY

Notch Signaling Regulates the Lifespan of Vascular Endothelial Cells via a p16-Dependent Pathway

(2014) Yohko Yoshida et al.   PLoS One

Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders

(2013) Anu Kauppinen et al.   CELLULAR SIGNALLING

High Glucose Induced Alteration of SIRTs in Endothelial Cells Causes Rapid Aging in a p300 and FOXO Regulated Pathway

(2013) Rokhsana Mortuza et al.   PLoS One

Oncogene- and Oxidative Stress-Induced Cellular Senescence Shows Distinct Expression Patterns of Proinflammatory Cytokines in Vascular Endothelial Cells

(2013) Etsu Suzuki et al.   TheScientificWorldJOURNAL

Neurodegeneration in the diabetic eye: new insights and therapeutic perspectives

(2013) Rafael Simó et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The Endothelium Abridges Insulin Resistance to Premature Aging

(2013) Angelo Avogaro et al.   Journal of the American Heart Association

MicroRNA-34a regulates the longevity-associated protein SIRT1 in coronary artery disease: effect of statins on SIRT1 and microRNA-34a expression

(2012) Tsuyoshi Tabuchi et al.   CLINICAL SCIENCE

Novel Targets Against Retinal Angiogenesis in Diabetic Retinopathy

(2012) Shuang Wang et al.   Current Diabetes Reports

The Role of Angiogenesis in the Development of Proliferative Diabetic Retinopathy: Impact of Intravitreal Anti-VEGF Treatment

(2012) Gemma Tremolada et al.   Experimental Diabetes Research

SIRT1 Activators Suppress Inflammatory Responses through Promotion of p65 Deacetylation and Inhibition of NF-κB Activity

(2012) Hongying Yang et al.   PLoS One

miRandola: Extracellular Circulating MicroRNAs Database

(2012) Francesco Russo et al.   PLoS One

Prevalence of Diabetic Retinopathy in Various Ethnic Groups: A Worldwide Perspective

(2012) Sobha Sivaprasad et al.   SURVEY OF OPHTHALMOLOGY

Mechanisms Involved in the Aging-Induced Vascular Dysfunction

(2012) Mariam El Assar et al.   Frontiers in Physiology

RhoA-Mediated Signaling in Notch-Induced Senescence-Like Growth Arrest and Endothelial Barrier Dysfunction

(2011) Deepak Venkatesh et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Oxidative stress, glutathione status, sirtuin and cellular stress response in type 2 diabetes

(2011) V. Calabrese et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Early diabetic changes in the nerve fibre layer at the macula detected by spectral domain optical coherence tomography

(2011) H. Y.-L. Park et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)

(2011) Antero Salminen et al.   CELLULAR SIGNALLING

Trans-Chalcone prevents VEGF expression and retinal neovascularization in the ischemic retina

(2011) Folami Lamoke et al.   EXPERIMENTAL EYE RESEARCH

Caveolin-1, cellular senescence and age-related diseases

(2011) Huafei Zou et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Mature Peripheral RPE Cells Have an Intrinsic Capacity to Proliferate; A Potential Regulatory Mechanism for Age-Related Cell Loss

(2011) Ioannis Kokkinopoulos et al.   PLoS One

L-arginine attenuates high glucose-accelerated senescence in human umbilical vein endothelial cells

(2010) Weili Zhong et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Functional delivery of viral miRNAs via exosomes

(2010) D. M. Pegtel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endothelial dysfunction in aged humans is related with oxidative stress and vascular inflammation

(2009) Leocadio Rodríguez-Mañas et al.   AGING CELL

Held under arrest: Many mature albino RPE cells display polyploidal features consistent with abnormal cell cycle retention

(2009) Tom Adams et al.   EXPERIMENTAL EYE RESEARCH

Comparative Biology of Aging

(2009) S. N. Austad   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Normal Aging Involves Modulation of Specific Inflammatory Markers in the Rat Retina and Choroid

(2009) J. J. Steinle et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Amelioration of neurological and biochemical deficits by peroxynitrite decomposition catalysts in experimental diabetic neuropathy

(2008) Manish Arora et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Angiotensin II–Mediated Oxidative DNA Damage Accelerates Cellular Senescence in Cultured Human Vascular Smooth Muscle Cells via Telomere-Dependent and Independent Pathways

(2007) Karl E. Herbert et al.   CIRCULATION RESEARCH