Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
出版年份 2016 全文链接
标题
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
作者
关键词
-
出版物
Autophagy
Volume 12, Issue 1, Pages 1-222
出版商
Informa UK Limited
发表日期
2016-01-22
DOI
10.1080/15548627.2015.1100356
参考文献
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- 201st ENMC International Workshop: Autophagy in muscular dystrophies – Translational approach, 1–3 November 2013, Bussum, The Netherlands
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- Novel Quantitative Autophagy Analysis by Organelle Flow Cytometry after Cell Sonication
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- Autophagy Inhibitor LRPPRC Suppresses Mitophagy through Interaction with Mitophagy Initiator Parkin
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- Arginine starvation-associated atypical cellular death involves mitochondrial dysfunction, nuclear DNA leakage, and chromatin autophagy
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- Vmp1 Regulates PtdIns3P Signaling During Autophagosome Formation inDictyostelium discoideum
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- PICALM modulates autophagy activity and tau accumulation
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- A non-conserved miRNA regulates lysosomal function and impacts on a human lysosomal storage disorder
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- ATG5 defines a phagophore domain connected to the endoplasmic reticulum during autophagosome formation in plants
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- Functional Genomics Evidence Unearths New Moonlighting Roles of Outer Ring Coat Nucleoporins
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- A retrospective cohort study identifying the principal pathological features useful in the diagnosis of inclusion body myositis
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- Antagonism of Tumoral Prolactin Receptor Promotes Autophagy-Related Cell Death
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- Aberrant Autolysosomal Regulation Is Linked to The Induction of Embryonic Senescence: Differential Roles of Beclin 1 and p53 in Vertebrate Spns1 Deficiency
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- Association of FKBP51 with Priming of Autophagy Pathways and Mediation of Antidepressant Treatment Response: Evidence in Cells, Mice, and Humans
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- A Simple Method to Estimate the Number of Autophagic Elements by Electron Microscopic Morphometry in Real Cellular Dimensions
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- A Molecular View of Autophagy in Lepidoptera
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- ROS-dependent prostate apoptosis response-4 (Par-4) up-regulation and ceramide generation are the prime signaling events associated with curcumin-induced autophagic cell death in human malignant glioma
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- Autophagy is altered in skeletal and cardiac muscle of spontaneously hypertensive rats
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- Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts
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- Balance between autophagic pathways preserves retinal homeostasis
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- 7-Ketocholesterol Induces Autophagy in Vascular Smooth Muscle Cells through Nox4 and Atg4B
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- Autophagic Degradation Contributes to Muscle Wasting in Cancer Cachexia
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- HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE
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- 20-hydroxyecdysone upregulatesAtggenes to induce autophagy in the Bombyx fat body
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- Autophagy receptor CALCOCO2/NDP52 takes center stage in Crohn disease
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- A conserved domain in exon 2 coding for the human and murine ARF tumor suppressor protein is required for autophagy induction
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- Spread of neuronal degeneration in a dopaminergic,Lrrk-G2019Smodel of Parkinson disease
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- Live-cell imaging ofAspergillus nidulansautophagy
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- Live imaging and single-cell analysis reveal differential dynamics of autophagy and apoptosis
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- Autophagy and phagocytosis converge for better vision
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- HMGB1 is involved in autophagy inhibition caused by SNCA/α-synuclein overexpression
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- Atg24-assisted mitophagy in the foot cells is necessary for proper asexual differentiation inMagnaporthe oryzae
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- Regulation of ATG8 membrane association by ATG4 in the parasitic protistToxoplasma gondii
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- Plasmodium falciparumATG8 implicated in both autophagy and apicoplast formation
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- Drosophila Fip200 is an essential regulator of autophagy that attenuates both growth and aging
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- Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons
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- Polyamine depletion inhibits the autophagic response modulatingTrypanosoma cruziinfectivity
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- The protonophore CCCP interferes with lysosomal degradation of autophagic cargo in yeast and mammalian cells
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- Ambra1knockdown in zebrafish leads to incomplete development due to severe defects in organogenesis
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- Ultrastructure of autophagy in plant cells
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- Modulation of intracellular calcium homeostasis blocks autophagosome formation
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- The TOMM machinery is a molecular switch in PINK1 and PARK2/PARKIN-dependent mitochondrial clearance
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- The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria
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- Direct uptake and degradation of DNA by lysosomes
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- Functions of autophagy in normal and diseased liver
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- Novel tamoxifen derivative Ridaifen-B induces Bcl-2 independent autophagy without estrogen receptor involvement
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- Induction of oxiapoptophagy, a mixed mode of cell death associated with oxidative stress, apoptosis and autophagy, on 7-ketocholesterol-treated 158N murine oligodendrocytes: Impairment by α-tocopherol
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- Mitochondrion-associated protein LRPPRC suppresses the initiation of basal levels of autophagy via enhancing Bcl-2 stability
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- miR-205 impairs the autophagic flux and enhances cisplatin cytotoxicity in castration-resistant prostate cancer cells
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- The pseudokinase tribbles homologue-3 plays a crucial role in cannabinoid anticancer action
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- Autophagy paradox and ceramide
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- Rapid screening of potential autophagic inductor agents using mammalian cell lines
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- Defective autophagy in spastizin mutated patients with hereditary spastic paraparesis type 15
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- Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells
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- LITAF, a BCL6 target gene, regulates autophagy in mature B-cell lymphomas
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- Autophagy and enhanced chemosensitivity in experimental pancreatic cancers induced by noninvasive radiofrequency field treatment
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- Chloroquine in Cancer Therapy: A Double-Edged Sword of Autophagy
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- Beclin 2 Functions in Autophagy, Degradation of G Protein-Coupled Receptors, and Metabolism
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- Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function
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- EGFR-Mediated Beclin 1 Phosphorylation in Autophagy Suppression, Tumor Progression, and Tumor Chemoresistance
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- Differential Regulation of Distinct Vps34 Complexes by AMPK in Nutrient Stress and Autophagy
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- mTOR Regulates Lysosomal ATP-Sensitive Two-Pore Na+ Channels to Adapt to Metabolic State
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- The Atg6/Vps30/Beclin 1 ortholog BEC-1 mediates endocytic retrograde transport in addition to autophagy inC. elegans
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- A proteolytic cleavage assay to monitor autophagy inDictyostelium discoideum
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- Atg35, a micropexophagy-specific protein that regulates micropexophagic apparatus formation inPichia pastoris
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- Autophagy-independent function of MAP-LC3 during intracellular propagation ofChlamydia trachomatis
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- ULK1 inhibits the kinase activity of mTORC1 and cell proliferation
- (2011) Chang Hwa Jung et al. Autophagy
- Atg1 allows second-signaled autophagic cell death in Dictyostelium
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- Autophagy in protists
- (2011) Michael Duszenko et al. Autophagy
- Sea urchin embryos as a model system for studying autophagy induced by cadmium stress
- (2011) Roberto Chiarelli et al. Autophagy
- The induction of autophagy by mechanical stress
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- Resveratrol-mediated autophagy requires WIPI-1-regulated LC3 lipidation in the absence of induced phagophore formation
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- Mitochondria removal by autophagy
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- For the last time, it is GFP-Atg8, not Atg8-GFP (and the same goes for LC3)
- (2011) Daniel J Klionsky Autophagy
- Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition
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- Coronavirus nsp6 proteins generate autophagosomes from the endoplasmic reticulum via an omegasome intermediate
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- The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR
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- Seeing is believing: The impact of electron microscopy on autophagy research
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- ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding
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- Ulk1-mediated phosphorylation of AMPK constitutes a negative regulatory feedback loop
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- Dissecting the dynamic turnover of GFP-LC3 in the autolysosome
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- Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction
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- Hepatitis B virus X protein reduces starvation-induced cell death through activation of autophagy and inhibition of mitochondrial apoptotic pathway
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- Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis software
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- Autophagy induced by rapamycin and carbon-starvation have distinct proteome profiles in Aspergillus nidulans
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- BCR-ABL suppresses autophagy through ATF5-mediated regulation of mTOR transcription
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- MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1-regulated pathways in mice
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- Concurrent detection of autolysosome formation and lysosomal degradation by flow cytometry in a high-content screen for inducers of autophagy
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- Expression of autophagy-related genes in the anterior silk gland of the silkworm (Bombyx mori) during metamorphosis
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- Spectral imaging-based methods for quantifying autophagy and apoptosis
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- Atorvastatin induces autophagy in prostate cancer PC3 cells through activation ofLC3transcription
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- Histone deacetylase inhibition induces apoptosis and autophagy in human neuroblastoma cells
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- Following Cytochrome c Release, Autophagy Is Inhibited during Chemotherapy-Induced Apoptosis by Caspase 8-Mediated Cleavage of Beclin 1
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- SNARE Proteins Are Required for Macroautophagy
- (2011) Usha Nair et al. CELL
- RalB and the Exocyst Mediate the Cellular Starvation Response by Direct Activation of Autophagosome Assembly
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- Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis
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- Identification of Aneuploidy-Selective Antiproliferation Compounds
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- Autophagosome Precursor Maturation Requires Homotypic Fusion
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- Beclin1 Controls the Levels of p53 by Regulating the Deubiquitination Activity of USP10 and USP13
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- A dual role for Ca2+ in autophagy regulation
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- Stimulation of the midkine/ALK axis renders glioma cells resistant to cannabinoid antitumoral action
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- Autophagy promotes survival of retinal ganglion cells after optic nerve axotomy in mice
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- PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk
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- Autophagy and BiP level decrease are early key events in retrograde degeneration of motoneurons
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- Mitochondrially localized PKA reverses mitochondrial pathology and dysfunction in a cellular model of Parkinson's disease
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- The Beclin 1 network regulates autophagy and apoptosis
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- Morphological classification of plant cell deaths
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- A Tecpr1-Dependent Selective Autophagy Pathway Targets Bacterial Pathogens
- (2011) Michinaga Ogawa et al. Cell Host & Microbe
- Autophagy Regulates Cholesterol Efflux from Macrophage Foam Cells via Lysosomal Acid Lipase
- (2011) Mireille Ouimet et al. Cell Metabolism
- Eating the strangers within: host control of intracellular bacteria via xenophagy
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- A Sensitive and Quantitative Technique for Detecting Autophagic Events Based on Lysosomal Delivery
- (2011) Hiroyuki Katayama et al. CHEMISTRY & BIOLOGY
- Importance of cholesterol and oxysterols metabolism in the pharmacology of tamoxifen and other AEBS ligands
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- Autophagy and p62 in Cardiac Proteinopathy
- (2011) Qingwen Zheng et al. CIRCULATION RESEARCH
- Novel Phosphoinositide 3-Kinase/mTOR Dual Inhibitor, NVP-BGT226, Displays Potent Growth-Inhibitory Activity against Human Head and Neck Cancer Cells In Vitro and In Vivo
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- The p62 antibody reveals various cytoplasmic protein aggregates in spinocerebellar ataxia Type 6
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- Autophagy and Lipid Metabolism Coordinately Modulate Life Span in Germline-less C. elegans
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- The Professional Phagocyte Dictyostelium discoideum as a Model Host for Bacterial Pathogens
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- Origin and function of the stalk-cell vacuole in Dictyostelium
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- Autophagy Proteins Regulate the Secretory Component of Osteoclastic Bone Resorption
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- The WD40 Repeat PtdIns(3)P-Binding Protein EPG-6 Regulates Progression of Omegasomes to Autophagosomes
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- Microautophagy of Cytosolic Proteins by Late Endosomes
- (2011) Ranjit Sahu et al. DEVELOPMENTAL CELL
- Inhibition of autophagy by TAB2 and TAB3
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- Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β
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- Temporal orchestration of circadian autophagy rhythm by C/EBPβ
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- p53 directly suppresses BNIP3 expression to protect against hypoxia-induced cell death
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- microRNA-101 is a potent inhibitor of autophagy
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- BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins
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- Role and regulation of autophagy in the development of acinar structures formed by bovine BME-UV1 mammary epithelial cells
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- At the core of survival: Autophagy delays the onset of both apoptotic and necrotic cell death in a model of ischemic cell injury
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- Transmembrane protein 166 regulates autophagic and apoptotic activities following focal cerebral ischemic injury in rats
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- Functional interaction of heat shock protein 90 and Beclin 1 modulates Toll-like receptor-mediated autophagy
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- Defective relocalization of ALS2/alsin missense mutants to Rac1-induced macropinosomes accounts for loss of their cellular function and leads to disturbed amphisome formation
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- Cytotoxicity of red fluorescent protein DsRed is associated with the suppression of Bcl-xL translation
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- Lysosomal thiol reductase negatively regulates autophagy by altering glutathione synthesis and oxidation
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- Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis
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- AMP-activated protein kinase--an energy sensor that regulates all aspects of cell function
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- High Beclin 1 expression defines a poor prognosis in endometrial adenocarcinomas
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- Muscle choline kinase beta defect causes mitochondrial dysfunction and increased mitophagy
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- Lafora bodies and neurological defects in malin-deficient mice correlate with impaired autophagy
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- Silencing of frataxin gene expression triggers p53-dependent apoptosis in human neuron-like cells
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- Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways
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- Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease
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- Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy
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- Autophagy in immunity and cell-autonomous defense against intracellular microbes
- (2011) Vojo Deretic IMMUNOLOGICAL REVIEWS
- Autophagy modulates the Mycobacterium tuberculosis-induced cytokine response
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- The role of lysosomes in iron metabolism and recycling
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- Peroxisome degradation in mammals
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- Crucial role for autophagy in degranulation of mast cells
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- TGF -activated kinase 1 (TAK1)-binding proteins (TAB) 2 and 3 negatively regulate autophagy
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- Regulation of Autophagy by Neuropathological Protein TDP-43
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- Fatty Acids Suppress Autophagic Turnover in β-Cells
- (2011) Guy Las et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Hierarchical Whole-body Modeling Approach Elucidates the Link betweenin VitroInsulin Signaling andin VivoGlucose Homeostasis
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- Flavivirus NS4A-induced Autophagy Protects Cells against Death and Enhances Virus Replication
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- Identification of Small Molecule Inhibitors of Phosphatidylinositol 3-Kinase and Autophagy
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- Aspartyl Aminopeptidase Is Imported from the Cytoplasm to the Vacuole by Selective Autophagy inSaccharomyces cerevisiae
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- A Novel TIP30 Protein Complex Regulates EGF Receptor Signaling and Endocytic Degradation
- (2011) Chengliang Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Regulates Autophagy in Cultured Astrocytes
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- Parkin Mediates Proteasome-dependent Protein Degradation and Rupture of the Outer Mitochondrial Membrane
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- Dynamics of the Degradation of Ubiquitinated Proteins by Proteasomes and Autophagy
- (2011) Natura Myeku et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation of Autophagy of Aggregation-prone Ubiquitinated Proteins by Timosaponin A-III
- (2011) Chun-Nam Lok et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glucocorticoid Elevation of Dexamethasone-induced Gene 2 (Dig2/RTP801/REDD1) Protein Mediates Autophagy in Lymphocytes
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- Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation
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- Microtubule-associated Protein 1S (MAP1S) Bridges Autophagic Components with Microtubules and Mitochondria to Affect Autophagosomal Biogenesis and Degradation
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- OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation
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- Two MAPK-signaling pathways are required for mitophagy inSaccharomyces cerevisiae
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- Biogenesis of a novel compartment for autophagosome-mediated unconventional protein secretion
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- Autophagic substrate clearance requires activity of the syntaxin-5 SNARE complex
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- Identification of PTP as an autophagic phosphatase
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- Chaperone-mediated autophagy at a glance
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- Freeze-fracture replica immunolabelling reveals human WIPI-1 and WIPI-2 as membrane proteins of autophagosomes
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- The novel phloroglucinol PMT7 kills glycolytic cancer cells by blocking autophagy and sensitizing to nutrient stress
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- Insufficient Activation of Autophagy Allows Cellular Damage to Accumulate in Critically Ill Patients
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- Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells
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- Autophagic Activity and Aging in Human Odontoblasts
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- Retrograde heart perfusion: The Langendorff technique of isolated heart perfusion
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- Induction of autophagy with catalytic mTOR inhibitors reduces huntingtin aggregates in a neuronal cell model
- (2011) Ana Roscic et al. JOURNAL OF NEUROCHEMISTRY
- The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
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- Presenilin Is Necessary for Efficient Proteolysis through the Autophagy-Lysosome System in a -Secretase-Independent Manner
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- Lysosomal Proteolysis Inhibition Selectively Disrupts Axonal Transport of Degradative Organelles and Causes an Alzheimer's-Like Axonal Dystrophy
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- Autophagy Protects the Proximal Tubule from Degeneration and Acute Ischemic Injury
- (2011) T. Kimura et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Zoledronic Acid Induces Autophagic Cell Death in Human Prostate Cancer Cells
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- Autophagosome Formation during Varicella-Zoster Virus Infection following Endoplasmic Reticulum Stress and the Unfolded Protein Response
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- Pleiotropic Action of AP-1 in v-Src-Transformed Cells
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- Inhibition of active autophagy induces apoptosis and increases chemosensitivity in cholangiocarcinoma
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- Beclin-1 and LC3A expression in cutaneous malignant melanomas
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- Autophagy patterns and prognosis in uveal melanomas
- (2011) Alexandra N Giatromanolaki et al. MODERN PATHOLOGY
- A Conserved Coatomer-related Complex Containing Sec13 and Seh1 Dynamically Associates With the Vacuole inSaccharomyces cerevisiae
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- Autophagy Driven by a Master Regulator of Hematopoiesis
- (2011) Y.-A. Kang et al. MOLECULAR AND CELLULAR BIOLOGY
- Distinct Mechanisms of Ferritin Delivery to Lysosomes in Iron-Depleted and Iron-Replete Cells
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- Relieving Autophagy and 4EBP1 from Rapamycin Resistance
- (2011) B. Nyfeler et al. MOLECULAR AND CELLULAR BIOLOGY
- A GDI (AGS3) and a GEF (GIV) regulate autophagy by balancing G protein activity and growth factor signals
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- The LC3 recruitment mechanism is separate from Atg9L1-dependent membrane formation in the autophagic response against Salmonella
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- Selective regulation of autophagy by the Iml1-Npr2-Npr3 complex in the absence of nitrogen starvation
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- A Lipid-Modified Estrogen Derivative that Treats Breast Cancer Independent of Estrogen Receptor Expression through Simultaneous Induction of Autophagy and Apoptosis
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- Blockade of Fatty Acid Synthase Induces Ubiquitination and Degradation of Phosphoinositide-3-Kinase Signaling Proteins in Ovarian Cancer
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- p62 Is a Key Regulator of Nutrient Sensing in the mTORC1 Pathway
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- Serine 403 Phosphorylation of p62/SQSTM1 Regulates Selective Autophagic Clearance of Ubiquitinated Proteins
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- Complex Inhibitory Effects of Nitric Oxide on Autophagy
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- Hsp90-Cdc37 Chaperone Complex Regulates Ulk1- and Atg13-Mediated Mitophagy
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- Distinct Autophagosomal-Lysosomal Fusion Mechanism Revealed by Thapsigargin-Induced Autophagy Arrest
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- Ca2+/Calmodulin-Dependent Kinase (CaMK) Signaling via CaMKI and AMP-Activated Protein Kinase Contributes to the Regulation of WIPI-1 at the Onset of Autophagy
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- Image-based genome-wide siRNA screen identifies selective autophagy factors
- (2011) Anthony Orvedahl et al. NATURE
- HDACs link the DNA damage response, processing of double-strand breaks and autophagy
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- Autophagy in immunity and inflammation
- (2011) Beth Levine et al. NATURE
- Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease
- (2011) Alan S. L. Wong et al. NATURE CELL BIOLOGY
- During autophagy mitochondria elongate, are spared from degradation and sustain cell viability
- (2011) Ligia C. Gomes et al. NATURE CELL BIOLOGY
- Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes
- (2011) Oliver Florey et al. NATURE CELL BIOLOGY
- AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
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- AMP-activated protein kinase: nature's energy sensor
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- A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease
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- Autophagy induced by valproic acid is associated with oxidative stress in glioma cell lines
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- Lanatoside C sensitizes glioblastoma cells to tumor necrosis factor–related apoptosis-inducing ligand and induces an alternative cell death pathway
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- ATP13A2 regulates mitochondrial bioenergetics through macroautophagy
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- The accumulation of neurotoxic proteins, induced by proteasome inhibition, is reverted by trehalose, an enhancer of autophagy, in human neuroblastoma cells
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- Restriction of trophic factors and nutrients induces PARKIN expression
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- Macroautophagy and the proteasome are differently involved in the degradation of alpha-synuclein wild type and mutated A30P in an in vitro inducible model (PC12/TetOn)
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- NAC1 modulates sensitivity of ovarian cancer cells to cisplatin by altering the HMGB1-mediated autophagic response
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- Cloning and characterization of the autophagy-related gene 6 from the hard tick, Haemaphysalis longicornis
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- Autophagy in term normal human placentas
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- TheArabidopsisDeubiquitinating Enzyme AMSH3 Interacts with ESCRT-III Subunits and Regulates Their Localization
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- TheArabidopsisMultistress Regulator TSPO Is a Heme Binding Membrane Protein and a Potential Scavenger of Porphyrins via an Autophagy-Dependent Degradation Mechanism
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- The ATG1/ATG13 Protein Kinase Complex Is Both a Regulator and a Target of Autophagic Recycling in Arabidopsis
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- Delivery of Prolamins to the Protein Storage Vacuole in Maize Aleurone Cells
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- BAG3 Directly Interacts with Mutated alphaB-Crystallin to Suppress Its Aggregation and Toxicity
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- Downregulation of VRK1 by p53 in Response to DNA Damage Is Mediated by the Autophagic Pathway
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- Unc-51/ATG1 Controls Axonal and Dendritic Development via Kinesin-Mediated Vesicle Transport in the Drosophila Brain
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- The Metabolic Consequences of Hepatic AMP-Kinase Phosphorylation in Rainbow Trout
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- Preconditioning Involves Selective Mitophagy Mediated by Parkin and p62/SQSTM1
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- SB202190-Induced Cell Type-Specific Vacuole Formation and Defective Autophagy Do Not Depend on p38 MAP Kinase Inhibition
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- Activation of Autophagy in a Rat Model of Retinal Ischemia following High Intraocular Pressure
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- rnaset2 mutant zebrafish model familial cystic leukoencephalopathy and reveal a role for RNase T2 in degrading ribosomal RNA
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- Glycogen synthase kinase (GSK)-3 promotes p70 ribosomal protein S6 kinase (p70S6K) activity and cell proliferation
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- Nrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic degradation
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- Autophagosome targeting and membrane curvature sensing by Barkor/Atg14(L)
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- RNS2, a conserved member of the RNase T2 family, is necessary for ribosomal RNA decay in plants
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- Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells
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- Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK
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- Spinster is required for autophagic lysosome reformation and mTOR reactivation following starvation
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- Ammonia-induced autophagy is independent of ULK1/ULK2 kinases
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- Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease
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- An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer
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- FLIP-mediated autophagy regulation in cell death control
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- Induction of autophagy by spermidine promotes longevity
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- Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1–phosphatidylinositol-3-kinase complex
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- Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages
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- Atg26-Mediated Pexophagy Is Required for Host Invasion by the Plant Pathogenic Fungus Colletotrichum orbiculare
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- Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation
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- Differential gene expression of the honey bee Apis mellifera associated with Varroa destructor infection
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- Macroautophagy inhibition sensitizes tamoxifen-resistant breast cancer cells and enhances mitochondrial depolarization
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- Interactions between cell death induced by statins and 7-ketocholesterol in rabbit aorta smooth muscle cells
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- Diet, Autophagy, and Cancer: A Review
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- NVP-BEZ235, a Dual PI3K/mTOR Inhibitor, Prevents PI3K Signaling and Inhibits the Growth of Cancer Cells with Activating PI3K Mutations
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- Association of Autophagy Defect with a Malignant Phenotype and Poor Prognosis of Hepatocellular Carcinoma
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- Blocked Autophagy Sensitizes Resistant Carcinoma Cells to Radiation Therapy
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- Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells
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- Ubiquitin Chain Editing Revealed by Polyubiquitin Linkage-Specific Antibodies
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- p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling
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- Williams–Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase
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- Comprehensive phenotypic analysis for identification of genes affecting growth under ethanol stress inSaccharomyces cerevisiae
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- The ATG12-Conjugating Enzyme ATG10 Is Essential for Autophagic Vesicle Formation in Arabidopsis thaliana
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- Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
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- The Chaperone-Mediated Autophagy Receptor Organizes in Dynamic Protein Complexes at the Lysosomal Membrane
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- Piecemeal Microautophagy of the Nucleus Requires the Core Macroautophagy Genes
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- An Atg4B Mutant Hampers the Lipidation of LC3 Paralogues and Causes Defects in Autophagosome Closure
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- The TP53INP2 Protein Is Required for Autophagy in Mammalian Cells
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- JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy
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- E2F1 regulates autophagy and the transcription of autophagy genes
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- Autophagy Plays a Role in Chloroplast Degradation during Senescence in Individually Darkened Leaves
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- A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans
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