Genome-wide census of ATF4 binding sites and functional profiling of trait-associated genetic variants overlapping ATF4 binding motifs
出版年份 2023 全文链接
标题
Genome-wide census of ATF4 binding sites and functional profiling of trait-associated genetic variants overlapping ATF4 binding motifs
作者
关键词
-
出版物
PLoS Genetics
Volume 19, Issue 10, Pages e1011014
出版商
Public Library of Science (PLoS)
发表日期
2023-11-01
DOI
10.1371/journal.pgen.1011014
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A stay of execution: ATF4 regulation and potential outcomes for the integrated stress response
- (2023) Graham Neill et al. Frontiers in Molecular Neuroscience
- Systematic analysis of intrinsic enhancer-promoter compatibility in the mouse genome
- (2022) Miguel Martinez-Ara et al. MOLECULAR CELL
- A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression
- (2022) Ioannis I. Verginadis et al. NATURE CELL BIOLOGY
- Compatibility rules of human enhancer and promoter sequences
- (2022) Drew T. Bergman et al. NATURE
- Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome
- (2021) Denis A. Baird et al. PLoS Genetics
- Regulatory genomic circuitry of human disease loci by integrative epigenomics
- (2021) Carles A. Boix et al. NATURE
- LocusZoom.js: interactive and embeddable visualization of genetic association study results
- (2021) Andrew P Boughton et al. BIOINFORMATICS
- Genome-wide enhancer maps link risk variants to disease genes
- (2021) Joseph Nasser et al. NATURE
- FIVEx: an interactive eQTL browser across public datasets
- (2021) Alan Kwong et al. BIOINFORMATICS
- A functional genomics pipeline identifies pleiotropy and cross-tissue effects within obesity-associated GWAS loci
- (2021) Amelia C. Joslin et al. Nature Communications
- Functional characterization of T2D-associated SNP effects on baseline and ER stress-responsive β cell transcriptional activation
- (2021) Shubham Khetan et al. Nature Communications
- A single-cell atlas of chromatin accessibility in the human genome
- (2021) Kai Zhang et al. CELL
- Biology of Activating Transcription Factor 4 (ATF4) and Its Role in Skeletal Muscle Atrophy
- (2021) Scott M Ebert et al. JOURNAL OF NUTRITION
- An open approach to systematically prioritize causal variants and genes at all published human GWAS trait-associated loci
- (2021) Edward Mountjoy et al. NATURE GENETICS
- A cross-population atlas of genetic associations for 220 human phenotypes
- (2021) Saori Sakaue et al. NATURE GENETICS
- The nf-core framework for community-curated bioinformatics pipelines
- (2020) Philip A. Ewels et al. NATURE BIOTECHNOLOGY
- HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expression
- (2020) Peng Huang et al. BLOOD
- The mutational constraint spectrum quantified from variation in 141,456 humans
- (2020) Konrad J. Karczewski et al. NATURE
- Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma
- (2020) Jiyeon Choi et al. Nature Communications
- Occupancy maps of 208 chromatin-associated proteins in one human cell type
- (2020) E. Christopher Partridge et al. NATURE
- A human-specific VNTR in the TRIB3 promoter causes gene expression variation between individuals
- (2020) Tiit Örd et al. PLoS Genetics
- Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations
- (2020) Ming-Huei Chen et al. CELL
- Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics
- (2020) Maya Ghoussaini et al. NUCLEIC ACIDS RESEARCH
- Genome-wide analysis identifies novel susceptibility loci for myocardial infarction
- (2020) Jaana A Hartiala et al. EUROPEAN HEART JOURNAL
- g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update)
- (2019) Uku Raudvere et al. NUCLEIC ACIDS RESEARCH
- ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression
- (2019) Feven Tameire et al. NATURE CELL BIOLOGY
- Functional testing of thousands of osteoarthritis-associated variants for regulatory activity
- (2019) Jason C. Klein et al. Nature Communications
- Comparative genetic architectures of schizophrenia in East Asian and European populations
- (2019) Max Lam et al. NATURE GENETICS
- Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
- (2019) Phil H. Lee et al. CELL
- TRIB3 limits FGF21 induction during in vitro and in vivo nutrient deficiencies by inhibiting C/EBP–ATF response elements in the Fgf21 promoter
- (2018) Tiit Örd et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Chemical stresses fail to mimic the unfolded protein response resulting from luminal load with unfolded polypeptides
- (2018) Timothy J. Bergmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activating Transcription Factor 4 (ATF4) regulates neuronal activity by controlling GABABR trafficking
- (2018) Carlo Corona et al. JOURNAL OF NEUROSCIENCE
- Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
- (2018) James J. Lee et al. NATURE GENETICS
- OUP accepted manuscript
- (2018) NUCLEIC ACIDS RESEARCH
- Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
- (2018) Gail Davies et al. Nature Communications
- UMI-tools: modeling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy
- (2017) Tom Smith et al. GENOME RESEARCH
- Static and Dynamic DNA Loops form AP-1-Bound Activation Hubs during Macrophage Development
- (2017) Douglas H. Phanstiel et al. MOLECULAR CELL
- Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
- (2017) Helen R Warren et al. NATURE GENETICS
- Combinatorial bZIP dimers display complex DNA-binding specificity landscapes
- (2017) José A Rodríguez-Martínez et al. eLife
- TRIB3 increases cell resistance to arsenite toxicity by limiting the expression of the glutathione-degrading enzyme CHAC1
- (2016) Daima Örd et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Direct Identification of Hundreds of Expression-Modulating Variants using a Multiplexed Reporter Assay
- (2016) Ryan Tewhey et al. CELL
- The integrated stress response
- (2016) Karolina Pakos‐Zebrucka et al. EMBO REPORTS
- Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver
- (2016) Michael E. Fusakio et al. MOLECULAR BIOLOGY OF THE CELL
- DNA-damage response gene GADD45A induces differentiation in hematopoietic stem cells without inhibiting cell cycle or survival
- (2016) Susanne Wingert et al. STEM CELLS
- TRIB3 enhances cell viability during glucose deprivation in HEK293-derived cells by upregulating IGFBP2, a novel nutrient deficiency survival factor
- (2015) Tiit Örd et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- CETCh-seq: CRISPR epitope tagging ChIP-seq of DNA-binding proteins
- (2015) Daniel Savic et al. GENOME RESEARCH
- The gene expression signature of anagrelide provides an insight into its mechanism of action and uncovers new regulators of megakaryopoiesis
- (2015) M. Ahluwalia et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- Specific Downregulation of Hippocampal ATF4 Reveals a Necessary Role in Synaptic Plasticity and Memory
- (2015) Silvia Pasini et al. Cell Reports
- ATF4 licenses C/EBPβ activity in human mesenchymal stem cells primed for adipogenesis
- (2015) Daniel M Cohen et al. eLife
- A forward genetic screen reveals novel independent regulators of ULBP1, an activating ligand for natural killer cells
- (2015) Benjamin G Gowen et al. eLife
- Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins
- (2014) Alfonso Buil et al. NATURE GENETICS
- Easy quantitative assessment of genome editing by sequence trace decomposition
- (2014) Eva K. Brinkman et al. NUCLEIC ACIDS RESEARCH
- Massively Parallel Reporter Assays in Cultured Mammalian Cells
- (2014) Alexandre Melnikov et al. Jove-Journal of Visualized Experiments
- Gadd45a regulates hematopoietic stem cell stress responses in mice
- (2013) Y. Chen et al. BLOOD
- Macrophage lipoprotein lipase modulates the development of atherosclerosis but not adiposity
- (2013) Manabu Takahashi et al. JOURNAL OF LIPID RESEARCH
- DISC1–ATF4 transcriptional repression complex: dual regulation of the cAMP-PDE4 cascade by DISC1
- (2013) T Soda et al. MOLECULAR PSYCHIATRY
- ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
- (2013) Jaeseok Han et al. NATURE CELL BIOLOGY
- The UPR in atherosclerosis
- (2013) Alex X. Zhou et al. Seminars in Immunopathology
- Heme-regulated eIF2 kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis
- (2012) R. N. V. S. Suragani et al. BLOOD
- Trib3 is regulated by IL-3 and affects bone marrow-derived mast cell survival and function
- (2012) Tiit Örd et al. CELLULAR IMMUNOLOGY
- Targeting the ATF4 pathway in cancer therapy
- (2012) Dean C Singleton et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- The accessible chromatin landscape of the human genome
- (2012) Robert E. Thurman et al. NATURE
- Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
- (2012) M. T. Maurano et al. SCIENCE
- Brain-Specific Disruption of the eIF2α Kinase PERK Decreases ATF4 Expression and Impairs Behavioral Flexibility
- (2012) Mimi A. Trinh et al. Cell Reports
- Role of ATF4 in regulation of autophagy and resistance to drugs and hypoxia
- (2011) Tomasz Rzymski et al. CELL CYCLE
- The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress
- (2011) Brian F. Teske et al. MOLECULAR BIOLOGY OF THE CELL
- GOSemSim: an R package for measuring semantic similarity among GO terms and gene products
- (2010) G. Yu et al. BIOINFORMATICS
- BEDTools: a flexible suite of utilities for comparing genomic features
- (2010) Aaron R. Quinlan et al. BIOINFORMATICS
- The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation
- (2010) Jiangbin Ye et al. EMBO JOURNAL
- The transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9
- (2010) Y. Takigawa et al. JOURNAL OF CELL SCIENCE
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
- Atf4 Regulates Obesity, Glucose Homeostasis, and Energy Expenditure
- (2009) J. Seo et al. DIABETES
- Elevated ATF4 Expression, in the Absence of Other Signals, Is Sufficient for Transcriptional Induction via CCAAT Enhancer-binding Protein-activating Transcription Factor Response Elements
- (2009) Jixiu Shan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
- (2009) Ben Langmead et al. GENOME BIOLOGY
- Activating transcription factor 4
- (2007) Kurosh Ameri et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
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