The gene expression signature of anagrelide provides an insight into its mechanism of action and uncovers new regulators of megakaryopoiesis

Transcriptional diversity during lineage commitment of human blood progenitors

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Anagrelide compared with hydroxyurea in WHO-classified essential thrombocythemia: the ANAHYDRET Study, a randomized controlled trial

(2013) H. Gisslinger et al.   BLOOD

Combination therapy of hydroxycarbamide with anagrelide in patients with essential thrombocythemia in the evaluation of Xagrid(R) efficacy and long-term safety study

(2013) L. Gugliotta et al.   HAEMATOLOGICA

Transcription factors in late megakaryopoiesis and related platelet disorders

(2013) M. R. Tijssen et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Canonical Wnt signaling in megakaryocytes regulates proplatelet formation

(2012) I. C. Macaulay et al.   BLOOD

Differential roles of cAMP and cGMP in megakaryocyte maturation and platelet biogenesis

(2012) Antonija Jurak Begonja et al.   EXPERIMENTAL HEMATOLOGY

Cyclic AMP Signaling Inhibits Megakaryocytic Differentiation by Targeting Transcription Factor 3 (E2A) Cyclin-dependent Kinase Inhibitor 1A (CDKN1A) Transcriptional Axis

(2012) Jeremy D. Rubinstein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Circulating Interleukin (IL)-8, IL-2R, IL-12, and IL-15 Levels Are Independently Prognostic in Primary Myelofibrosis: A Comprehensive Cytokine Profiling Study

(2011) Ayalew Tefferi et al.   JOURNAL OF CLINICAL ONCOLOGY

Development of antiproliferative phenylmaleimides that activate the unfolded protein response

(2010) Ulrike Muus et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Global gene expression reveals a set of new genes involved in the modification of cells during erythroid differentiation

(2010) A. F. Da Cunha et al.   CELL PROLIFERATION

Anagrelide represses GATA-1 and FOG-1 expression without interfering with thrombopoietin receptor signal transduction

(2010) M. AHLUWALIA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Regulation of hematopoietic stem cells by their mature progeny

(2010) C. A. de Graaf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A HaemAtlas: characterizing gene expression in differentiated human blood cells

(2009) Nicholas A. Watkins et al.   BLOOD

Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells

(2009) María Salazar et al.   JOURNAL OF CLINICAL INVESTIGATION

Reticulin Accumulation in Essential Thrombocythemia: Prognostic Significance and Relationship to Therapy

(2009) Peter J. Campbell et al.   JOURNAL OF CLINICAL ONCOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Halofuginone Inhibits TH17 Cell Differentiation by Activating the Amino Acid Starvation Response

(2009) M. S. Sundrud et al.   SCIENCE

EPO receptor circuits for primary erythroblast survival

(2008) P. Sathyanarayana et al.   BLOOD

TRB3 suppresses adipocyte differentiation by negatively regulating PPARγ transcriptional activity

(2008) Yu Takahashi et al.   JOURNAL OF LIPID RESEARCH

Gene Ontology-driven transcriptional analysis of CD34+ cell-initiated megakaryocytic cultures identifies new transcriptional regulators of megakaryopoiesis

(2008) Peter G. Fuhrken et al.   PHYSIOLOGICAL GENOMICS