标题
A single-cell atlas of chromatin accessibility in the human genome
作者
关键词
single cell ATAC-seq, GWAS, cis, regulatory elements, enhancers, chromatin accessibility, epigenome, noncoding variants
出版物
CELL
Volume 184, Issue 24, Pages 5985-6001.e19
出版商
Elsevier BV
发表日期
2021-11-12
DOI
10.1016/j.cell.2021.10.024
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Regulatory genomic circuitry of human disease loci by integrative epigenomics
- (2021) Carles A. Boix et al. NATURE
- Systematic analysis of binding of transcription factors to noncoding variants
- (2021) Jian Yan et al. NATURE
- Comprehensive analysis of single cell ATAC-seq data with SnapATAC
- (2021) Rongxin Fang et al. Nature Communications
- Twelve years of SAMtools and BCFtools
- (2021) Petr Danecek et al. GigaScience
- Genome-wide enhancer maps link risk variants to disease genes
- (2021) Joseph Nasser et al. NATURE
- Single-cell chromatin accessibility identifies pancreatic islet cell type– and state-specific regulatory programs of diabetes risk
- (2021) Joshua Chiou et al. NATURE GENETICS
- Cardiac cell type–specific gene regulatory programs and disease risk association
- (2021) James D. Hocker et al. Science Advances
- Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution
- (2021) Alexandro E. Trevino et al. CELL
- An atlas of gene regulatory elements in adult mouse cerebrum
- (2021) Yang Eric Li et al. NATURE
- A brief history of human disease genetics
- (2020) Melina Claussnitzer et al. NATURE
- Single-cell multimodal omics: the power of many
- (2020) Chenxu Zhu et al. NATURE METHODS
- Role of IRF8 in immune cells functions, protection against infections, and susceptibility to inflammatory diseases
- (2020) Sandra Salem et al. HUMAN GENETICS
- Index and biological spectrum of human DNase I hypersensitive sites
- (2020) Wouter Meuleman et al. NATURE
- Global reference mapping of human transcription factor footprints
- (2020) Jeff Vierstra et al. NATURE
- Expanded encyclopaedias of DNA elements in the human and mouse genomes
- (2020) Jill E. Moore et al. NATURE
- Cells of the adult human heart
- (2020) Monika Litviňuková et al. NATURE
- Single-cell epigenomic analyses implicate candidate causal variants at inherited risk loci for Alzheimer’s and Parkinson’s diseases
- (2020) M. Ryan Corces et al. NATURE GENETICS
- The epigenetic basis of cellular heterogeneity
- (2020) Benjamin Carter et al. NATURE REVIEWS GENETICS
- Genome-wide association analysis of diverticular disease points towards neuromuscular, connective tissue and epithelial pathomechanisms
- (2019) Clemens Schafmayer et al. GUT
- Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk
- (2019) Iris E. Jansen et al. NATURE GENETICS
- Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data
- (2019) Ioanna Tachmazidou et al. NATURE GENETICS
- Chromatin accessibility and the regulatory epigenome
- (2019) Sandy L. Klemm et al. NATURE REVIEWS GENETICS
- Taiji: System-level identification of key transcription factors reveals transcriptional waves in mouse embryonic development
- (2019) Kai Zhang et al. Science Advances
- A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome
- (2019) Akira Wiberg et al. Nature Communications
- New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries
- (2019) Nick Shrine et al. NATURE GENETICS
- Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations
- (2019) Phuwanat Sakornsakolpat et al. NATURE GENETICS
- The accessible chromatin landscape of the murine hippocampus at single-cell resolution
- (2019) John R. Sinnamon et al. GENOME RESEARCH
- Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
- (2019) Nicole M. Warrington et al. NATURE GENETICS
- Varicose veins of lower extremities: Insights from the first large-scale genetic study
- (2019) Alexandra S. Shadrina et al. PLoS Genetics
- Scrublet: Computational Identification of Cell Doublets in Single-Cell Transcriptomic Data
- (2019) Samuel L. Wolock et al. Cell Systems
- Droplet-based combinatorial indexing for massive-scale single-cell chromatin accessibility
- (2019) Caleb A. Lareau et al. NATURE BIOTECHNOLOGY
- High-throughput single-cell ChIP-seq identifies heterogeneity of chromatin states in breast cancer
- (2019) Kevin Grosselin et al. NATURE GENETICS
- A catalog of genetic loci associated with kidney function from analyses of a million individuals
- (2019) Matthias Wuttke et al. NATURE GENETICS
- Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies
- (2019) Milton Pividori et al. Lancet Respiratory Medicine
- A global overview of pleiotropy and genetic architecture in complex traits
- (2019) Kyoko Watanabe et al. NATURE GENETICS
- A compendium of promoter-centered long-range chromatin interactions in the human genome
- (2019) Inkyung Jung et al. NATURE GENETICS
- Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility
- (2019) SCIENCE
- Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations
- (2019) Charles P. Fulco et al. NATURE GENETICS
- Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels
- (2019) Adrienne Tin et al. NATURE GENETICS
- Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors
- (2018) Laleh Haghverdi et al. NATURE BIOTECHNOLOGY
- A large electronic-health-record-based genome-wide study of serum lipids
- (2018) Thomas J. Hoffmann et al. NATURE GENETICS
- Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
- (2018) Rainer Malik et al. NATURE GENETICS
- Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation
- (2018) Sebastian Preissl et al. NATURE NEUROSCIENCE
- From genome-wide associations to candidate causal variants by statistical fine-mapping
- (2018) Daniel J. Schaid et al. NATURE REVIEWS GENETICS
- A Single-Cell Atlas of In Vivo Mammalian Chromatin Accessibility
- (2018) Darren A. Cusanovich et al. CELL
- Cicero Predicts cis-Regulatory DNA Interactions from Single-Cell Chromatin Accessibility Data
- (2018) Hannah A. Pliner et al. MOLECULAR CELL
- Biobank-driven genomic discovery yields new insight into atrial fibrillation biology
- (2018) Jonas B. Nielsen et al. NATURE GENETICS
- Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
- (2018) Anubha Mahajan et al. NATURE GENETICS
- GENCODE reference annotation for the human and mouse genomes
- (2018) Adam Frankish et al. NUCLEIC ACIDS RESEARCH
- The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019
- (2018) Annalisa Buniello et al. NUCLEIC ACIDS RESEARCH
- Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation
- (2018) Alexander Teumer et al. Nature Communications
- Association analysis identifies 65 new breast cancer risk loci
- (2017) Kyriaki Michailidou et al. NATURE
- Integrative single-cell analysis of transcriptional and epigenetic states in the human adult brain
- (2017) Blue B Lake et al. NATURE BIOTECHNOLOGY
- Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7
- (2017) Yang Luo et al. NATURE GENETICS
- Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis
- (2017) John P Kemp et al. NATURE GENETICS
- Enhancing GTEx by bridging the gaps between genotype, gene expression, and disease
- (2017) Barbara E Stranger et al. NATURE GENETICS
- Single-cell methylomes identify neuronal subtypes and regulatory elements in mammalian cortex
- (2017) Chongyuan Luo et al. SCIENCE
- Myosin content of individual human muscle fibers isolated by laser capture microdissection
- (2016) Charles A. Stuart et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease
- (2016) William J. Astle et al. CELL
- Cutting Edge: Expression of IRF8 in Gastric Epithelial Cells Confers Protective Innate Immunity againstHelicobacter pyloriInfection
- (2016) Ming Yan et al. JOURNAL OF IMMUNOLOGY
- Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease
- (2016) Sun-Gou Ji et al. NATURE GENETICS
- Common variants at PVT1, ATG13–AMBRA1, AHI1 and CLEC16A are associated with selective IgA deficiency
- (2016) Paola G Bronson et al. NATURE GENETICS
- Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants
- (2016) Ying Jin et al. NATURE GENETICS
- Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels
- (2016) Tuomas O. Kilpeläinen et al. Nature Communications
- A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project
- (2015) Latarsha J. Carithers et al. BIOPRESERVATION AND BIOBANKING
- Droplet Barcoding for Single-Cell Transcriptomics Applied to Embryonic Stem Cells
- (2015) Allon M. Klein et al. CELL
- Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets
- (2015) Evan Z. Macosko et al. CELL
- Integrative analysis of 111 reference human epigenomes
- (2015) Anshul Kundaje et al. NATURE
- A global reference for human genetic variation
- (2015) Richard A. Gibbs et al. NATURE
- A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease
- (2015) Majid Nikpay et al. NATURE GENETICS
- Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus
- (2015) James Bentham et al. NATURE GENETICS
- Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis
- (2015) Lavinia Paternoster et al. NATURE GENETICS
- Partitioning heritability by functional annotation using genome-wide association summary statistics
- (2015) Hilary K Finucane et al. NATURE GENETICS
- LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
- (2015) Brendan K Bulik-Sullivan et al. NATURE GENETICS
- Multiplex single-cell profiling of chromatin accessibility by combinatorial cellular indexing
- (2015) D. A. Cusanovich et al. SCIENCE
- International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways
- (2015) Heather J. Cordell et al. Nature Communications
- A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project
- (2015) Latarsha J. Carithers et al. Biopreservation and Biobanking
- Developmental myosins: expression patterns and functional significance
- (2015) Stefano Schiaffino et al. Skeletal Muscle
- Cardiogenic Genes Expressed in Cardiac Fibroblasts Contribute to Heart Development and Repair
- (2014) Milena B. Furtado et al. CIRCULATION RESEARCH
- An atlas of active enhancers across human cell types and tissues
- (2014) Robin Andersson et al. NATURE
- Transcriptional enhancers: from properties to genome-wide predictions
- (2014) Daria Shlyueva et al. NATURE REVIEWS GENETICS
- Genetics of rheumatoid arthritis contributes to biology and drug discovery
- (2013) Yukinori Okada et al. NATURE
- Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
- (2013) Jason D Buenrostro et al. NATURE METHODS
- A map of the cis-regulatory sequences in the mouse genome
- (2012) Yin Shen et al. NATURE
- A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
- (2012) Alisa K Manning et al. NATURE GENETICS
- Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
- (2012) M. T. Maurano et al. SCIENCE
- Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
- (2011) R. J. Strawbridge et al. DIABETES
- Tbx20 regulates a genetic program essential to adult mouse cardiomyocyte function
- (2011) Tao Shen et al. JOURNAL OF CLINICAL INVESTIGATION
- Mapping and analysis of chromatin state dynamics in nine human cell types
- (2011) Jason Ernst et al. NATURE
- Narrow scope for resolution-limit-free community detection
- (2011) V. A. Traag et al. PHYSICAL REVIEW E
- Fiber Types in Mammalian Skeletal Muscles
- (2011) Stefano Schiaffino et al. PHYSIOLOGICAL REVIEWS
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
- GREAT improves functional interpretation of cis-regulatory regions
- (2010) Cory Y McLean et al. NATURE BIOTECHNOLOGY
- Common SNPs explain a large proportion of the heritability for human height
- (2010) Jian Yang et al. NATURE GENETICS
- Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
- (2010) Richa Saxena et al. NATURE GENETICS
- Ets Transcription Factors Control Epithelial Maturation and Transit and Crypt-Villus Morphogenesis in the Mammalian Intestine
- (2009) Paul Jedlicka et al. AMERICAN JOURNAL OF PATHOLOGY
- Fast and accurate short read alignment with Burrows-Wheeler transform
- (2009) H. Li et al. BIOINFORMATICS
- Detection of nonneutral substitution rates on mammalian phylogenies
- (2009) K. S. Pollard et al. GENOME RESEARCH
- Bayes factors for genome-wide association studies: comparison withP-values
- (2008) Jon Wakefield GENETIC EPIDEMIOLOGY
- Model-based Analysis of ChIP-Seq (MACS)
- (2008) Yong Zhang et al. GENOME BIOLOGY
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