Cancer metabolism control by natural products: Pyruvate kinase M2 targeting therapeutics
出版年份 2022 全文链接
标题
Cancer metabolism control by natural products: Pyruvate kinase
M2
targeting therapeutics
作者
关键词
-
出版物
PHYTOTHERAPY RESEARCH
Volume 36, Issue 8, Pages 3181-3201
出版商
Wiley
发表日期
2022-07-07
DOI
10.1002/ptr.7534
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Isovitexin potentiated the antitumor activity of cisplatin by inhibiting the glucose metabolism of lung cancer cells and reduced cisplatin-induced immunotoxicity in mice
- (2021) Rui-Lin Chen et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Kaempferol Reverses Aerobic Glycolysis via miR-339-5p-Mediated PKM Alternative Splicing in Colon Cancer Cells
- (2021) Haili Wu et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Anti-Tumor Drug Discovery Based on Natural Product β-Elemene: Anti-Tumor Mechanisms and Structural Modification
- (2021) Ziqiang Bai et al. MOLECULES
- Chinese Poplar Propolis Inhibits MDA-MB-231 Cell Proliferation in an Inflammatory Microenvironment by Targeting Enzymes of the Glycolytic Pathway
- (2021) Junya Li et al. Journal of Immunology Research
- Quercetin Attenuates Brain Oxidative Alterations Induced by Iron Oxide Nanoparticles in Rats
- (2021) Mohamed F. Dora et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Dauricine inhibits proliferation and promotes death of melanoma cells via inhibition of Src/ STAT3 signaling
- (2021) Bo Deng et al. PHYTOTHERAPY RESEARCH
- Apoptotic effect of compound K in hepatocellular carcinoma cells via inhibition of glycolysis and Akt/ mTOR / c‐Myc signaling
- (2021) Nari Shin et al. PHYTOTHERAPY RESEARCH
- Discovery and development of tumor glycolysis rate-limiting enzyme inhibitors
- (2021) Xueyan Sun et al. BIOORGANIC CHEMISTRY
- Advance toward isolation, extraction, metabolism and health benefits of kaempferol, a major dietary flavonoid with future perspectives
- (2021) Li Yang et al. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
- Thymoquinone and its nanoformulation attenuate colorectal and breast cancers and alleviate doxorubicin-induced cardiotoxicity
- (2021) Ali H El-Far et al. Nanomedicine
- Mangifera indica Extracts as Novel PKM2 Inhibitors for Treatment of Triple Negative Breast Cancer
- (2021) Azhar Rasul et al. Biomed Research International
- Scutellarin resensitizes oxaliplatin-resistant colorectal cancer cells to oxaliplatin treatment through inhibition of PKM2
- (2021) Wei Sun et al. Molecular Therapy-Oncolytics
- Dihydroartemisinin mediating PKM2-caspase-8/3-GSDME axis for pyroptosis in esophageal squamous cell carcinoma
- (2021) Mingxia Jiang et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Antitumor Effect of Morusin via G1 Arrest and Antiglycolysis by AMPK Activation in Hepatocellular Cancer
- (2021) Ah-Reum Cho et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- TQFL12, a novel synthetic derivative of TQ, inhibits triple‐negative breast cancer metastasis and invasion through activating AMPK/ACC pathway
- (2021) Chunli Wei et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer
- (2021) Xingchen Liu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Physciosporin suppresses mitochondrial respiration, aerobic glycolysis, and tumorigenesis in breast cancer
- (2021) İsa Taş et al. PHYTOMEDICINE
- Curcumin and its derivatives in cancer therapy: Potentiating antitumor activity of cisplatin and reducing side effects
- (2021) Asal Jalal Abadi et al. PHYTOTHERAPY RESEARCH
- Redox-sensitive cyclophilin A elicits chemoresistance through realigning cellular oxidative status in colorectal cancer
- (2021) Liyuan Peng et al. Cell Reports
- Resveratrol Targets a Variety of Oncogenic and Oncosuppressive Signaling for Ovarian Cancer Prevention and Treatment
- (2021) Xue-Ling Xu et al. Antioxidants
- Senescent Colon and Breast Cancer Cells Induced by Doxorubicin Exhibit Enhanced Sensitivity to Curcumin, Caffeine, and Thymoquinone
- (2020) Ali H. El-Far et al. INTEGRATIVE CANCER THERAPIES
- PKM2 regulates angiogenesis of VR‐EPCs through modulating glycolysis, mitochondrial fission, and fusion
- (2020) Ranyue Ren et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Identification of Parthenolide Dimers as Activators of Pyruvate Kinase M2 in Xenografts of Glioblastoma Multiforme in Vivo
- (2020) Yahui Ding et al. JOURNAL OF MEDICINAL CHEMISTRY
- The synthetic oleanane triterpenoid CDDO-Me binds and inhibits pyruvate kinase M2
- (2020) Iaci N. Soares et al. Pharmacological Reports
- Pyruvate Kinase M2 and Cancer: The Role of PKM2 in Promoting Tumorigenesis
- (2020) Kulsoom Zahra et al. Frontiers in Oncology
- Shikonin inhibits growth, invasion and glycolysis of nasopharyngeal carcinoma cells through inactivating the phosphatidylinositol 3 kinase/AKT signal pathway
- (2020) Jingjing Zhang et al. ANTI-CANCER DRUGS
- OSU-A9 induced-reactive oxygen species cause cytotoxicity in duodenal and gastric cancer cells by decreasing phosphorylated nuclear pyruvate kinase M2 protein levels
- (2020) Chang-Fang Chiu et al. BIOCHEMICAL PHARMACOLOGY
- Biochemical and structural insights into how amino acids regulate pyruvate kinase muscle isoform 2
- (2020) Suparno Nandi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphoglycerate kinase 1 (PGK1) in cancer: A promising target for diagnosis and therapy
- (2020) Qi Fu et al. LIFE SCIENCES
- Resveratrol and Its Nanoformulation Attenuate Growth and the Angiogenesis of Xenograft and Orthotopic Colon Cancer Models
- (2020) Thangirala Sudha et al. MOLECULES
- Thymoquinone-chemotherapeutic combinations: new regimen to combat cancer and cancer stem cells
- (2020) Ali H. El-Far et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Identification of Gliotoxin isolated from marine fungus as a new pyruvate kinase M2 inhibitor
- (2020) Wei Tang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Quercetin Attenuates Pancreatic and Renal D-Galactose-Induced Aging-Related Oxidative Alterations in Rats
- (2020) Ali H. El-Far et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Anticancer Attributes of Cantharidin: Involved Molecular Mechanisms and Pathways
- (2020) Faiza Naz et al. MOLECULES
- A Licorice Roots Extract Induces Apoptosis and Cell Cycle Arrest and Improves Metabolism via Regulating MiRNAs in Liver Cancer Cells
- (2020) Abdel-Hady A. Abdel-Wahab et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Antitumor Effect of Shikonin, a PKM2 Inhibitor, in Cholangiocarcinoma Cell Lines
- (2020) UNCHALEE THONSRI et al. ANTICANCER RESEARCH
- Micheliolide Attenuates Lipopolysaccharide-Induced Inflammation by Modulating the mROS/NF-κB/NLRP3 Axis in Renal Tubular Epithelial Cells
- (2020) Xianghong Lei et al. MEDIATORS OF INFLAMMATION
- Anti-Angiogenic Properties of Ginsenoside Rg3
- (2020) Maryam Nakhjavani et al. MOLECULES
- Oxymatrine Inhibits Colorectal Cancer Metastasis via Attenuating PKM2-Mediated Aerobic Glycolysis
- (2020) Xiaoping Li et al. Cancer Management and Research
- Pyruvate Kinase M2 Promotes Prostate Cancer Metastasis Through Regulating ERK1/2-COX-2 Signaling
- (2020) Wenjing Guo et al. Frontiers in Oncology
- Shikonin differentially regulates glucose metabolism via PKM2 and HIF1α to overcome apoptosis in a refractory HCC cell line
- (2020) Wei Yang et al. LIFE SCIENCES
- A comprehensive understanding about the pharmacological effect of diallyl disulfide other than its anti-carcinogenic activities
- (2020) Haiyan He et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Pyruvate kinase M2 (PKM2) in cancer and cancer therapeutics
- (2020) Susi Zhu et al. CANCER LETTERS
- The Central Role of Glucokinase in Glucose Homeostasis: A Perspective 50 Years After Demonstrating the Presence of the Enzyme in Islets of Langerhans
- (2019) Franz M. Matschinsky et al. Frontiers in Physiology
- Combination of shikonin with paclitaxel overcomes multidrug resistance in human ovarian carcinoma cells in a P-gp-independent manner through enhanced ROS generation
- (2019) Zhu Wang et al. Chinese Medicine
- Metabolic reprogramming results in abnormal glycolysis in gastric cancer: a review
- (2019) Yuanda Liu et al. OncoTargets and Therapy
- Sirtuin-mediated deacetylation of hnRNP A1 suppresses glycolysis and growth in hepatocellular carcinoma
- (2019) Hao Yang et al. ONCOGENE
- Influence Factors of the Pharmacokinetics of Herbal Resourced Compounds in Clinical Practice
- (2019) Shi Sun et al. Evidence-based Complementary and Alternative Medicine
- PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma
- (2019) Jiao Feng et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Breaking Glucose Transporter 1/Pyruvate Kinase M2 Glycolytic Loop Is Required for Cantharidin Inhibition of Metastasis in Highly Metastatic Breast Cancer
- (2019) Yanhong Pan et al. Frontiers in Pharmacology
- Beta‐elemene inhibits breast cancer metastasis through blocking pyruvate kinase M2 dimerization and nuclear translocation
- (2019) Yanhong Pan et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Gliotoxin Enhances Autophagic Cell Death via the DAPK1-TAp63 Signaling Pathway in Paclitaxel-Resistant Ovarian Cancer Cells
- (2019) Ga-Bin Park et al. Marine Drugs
- PKM2, function and expression and regulation
- (2019) Ze Zhang et al. Cell and Bioscience
- Pharmacological properties and derivatives of shikonin—A review in recent years
- (2019) Chuanjie Guo et al. PHARMACOLOGICAL RESEARCH
- Benserazide is a novel inhibitor targeting PKM2 for melanoma treatment
- (2019) Youyou Zhou et al. INTERNATIONAL JOURNAL OF CANCER
- Carpesium abrotanoides (L.) Root as a Potential Source of Natural Anticancer Compounds: Targeting Glucose Metabolism and PKM2/HIF‐1α Axis of Breast Cancer Cells
- (2019) Xin‐Xin Chai et al. JOURNAL OF FOOD SCIENCE
- The role of pyruvate kinase M2 in anticancer therapeutic treatments (Review)
- (2019) Qiongli Su et al. Oncology Letters
- Oxymatrine exerts organ- and tissue-protective effects by regulating inflammation, oxidative stress, apoptosis, and fibrosis: From bench to bedside
- (2019) Xu Lan et al. PHARMACOLOGICAL RESEARCH
- Drug resistance induces the upregulation of H 2 S-producing enzymes in HCT116 colon cancer cells
- (2018) Ashley A. Untereiner et al. BIOCHEMICAL PHARMACOLOGY
- Thymoquinone: A novel strategy to combat cancer: A review
- (2018) Muhammad Imran et al. BIOMEDICINE & PHARMACOTHERAPY
- RIP1 and RIP3 contribute to shikonin-induced glycolysis suppression in glioma cells via increase of intracellular hydrogen peroxide
- (2018) Bin Lu et al. CANCER LETTERS
- 2′-hydroxycinnamaldehyde inhibits cancer cell proliferation and tumor growth by targeting the pyruvate kinase M2
- (2018) Yae Jin Yoon et al. CANCER LETTERS
- Diallyl Disulfide Inhibits Breast Cancer Stem Cell Progression and Glucose Metabolism by Targeting CD44/PKM2/AMPK Signaling
- (2018) Xinhua Xie et al. CURRENT CANCER DRUG TARGETS
- Natural Product Micheliolide (MCL) Irreversibly Activates Pyruvate Kinase M2 and Suppresses Leukemia
- (2018) Jing Li et al. JOURNAL OF MEDICINAL CHEMISTRY
- Shikonin enhances sensitization of gefitinib against wild-type EGFR non-small cell lung cancer via inhibition PKM2/stat3/cyclinD1 signal pathway
- (2018) Jian-cai Tang et al. LIFE SCIENCES
- Quercetin suppresses the mobility of breast cancer by suppressing glycolysis through Akt-mTOR pathway mediated autophagy induction
- (2018) Lijun Jia et al. LIFE SCIENCES
- Scutellarein from Scutellaria barbata induces apoptosis of human colon cancer HCT116 cells through the ROS-mediated mitochondria-dependent pathway
- (2018) Fei Guo et al. NATURAL PRODUCT RESEARCH
- Lapachol inhibits glycolysis in cancer cells by targeting pyruvate kinase M2
- (2018) Mani Shankar Babu et al. PLoS One
- Lapatinib Inhibits Breast Cancer Cell Proliferation by Influencing PKM2 Expression
- (2018) Mingxiu Guan et al. TECHNOLOGY IN CANCER RESEARCH & TREATMENT
- LY294002 inhibits the Warburg effect in gastric cancer cells by downregulating pyruvate kinase M2
- (2018) Jian Lu et al. Oncology Letters
- Curcumin decreases Warburg effect in cancer cells by down-regulating pyruvate kinase M2 via mTOR-HIF1α inhibition
- (2018) Farid Ahmad Siddiqui et al. Scientific Reports
- Enhancing 5-fluorouracil efficacy through suppression of PKM2 in colorectal cancer cells
- (2018) Yong Cao et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Dauricine upregulates the chemosensitivity of hepatocellular carcinoma cells: Role of repressing glycolysis via miR-199a:HK2/PKM2 modulation
- (2018) Wei Li et al. FOOD AND CHEMICAL TOXICOLOGY
- Malic Enzyme 2 as a Potential Therapeutic Drug Target for Cancer
- (2018) Iqra Sarfraz et al. IUBMB LIFE
- Tannic acid directly targets pyruvate kinase isoenzyme M2 to attenuate colon cancer cell proliferation
- (2018) Peng Yang et al. Food & Function
- Protective Roles of Thymoquinone Nanoformulations: Potential Nanonutraceuticals in Human Diseases
- (2018) Ali El-Far et al. Nutrients
- Shikonin Inhibits Tumor Growth in Mice by Suppressing Pyruvate Kinase M2-mediated Aerobic Glycolysis
- (2018) Xiaoyue Zhao et al. Scientific Reports
- Shikonin exerts antitumor activity by causing mitochondrial dysfunction in hepatocellular carcinoma through PKM2-AMPK-PGC1α signaling pathway
- (2018) Bing Liu et al. Biochemistry and Cell Biology
- Targeting Pyruvate Kinase M2 and Hexokinase II, Pachymic Acid Impairs Glucose Metabolism and Induces Mitochondrial Apoptosis
- (2018) Guopeng Miao et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Physciosporin suppresses the proliferation, motility and tumourigenesis of colorectal cancer cells
- (2018) İsa Taş et al. PHYTOMEDICINE
- Discovery of novel naphthoquinone derivatives as inhibitors of the tumor cell specific M2 isoform of pyruvate kinase
- (2017) Xianling Ning et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Lapachol and lapachone analogs: a journey of two decades of patent research(1997-2016)
- (2017) Hidayat Hussain et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Adenosine Monophosphate (AMP)-Activated Protein Kinase: A New Target for Nutraceutical Compounds
- (2017) Fabiola Marín-Aguilar et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Apigenin Restrains Colon Cancer Cell Proliferation via Targeted Blocking of Pyruvate Kinase M2-Dependent Glycolysis
- (2017) Shuhua Shan et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Molecular docking and molecular dynamics simulation analyses of urea with ammoniated and ammoxidized lignin
- (2017) Wenzhuo Li et al. JOURNAL OF MOLECULAR GRAPHICS & MODELLING
- Oroxylin A activates PKM1/HNF4 alpha to induce hepatoma differentiation and block cancer progression
- (2017) Libin Wei et al. Cell Death & Disease
- 18F-fluorodeoxyglucose uptake predicts PKM2 expression in lung adenocarcinoma
- (2017) Ping Huang et al. Oncotarget
- Protein-Ligand Blind Docking Using QuickVina-W With Inter-Process Spatio-Temporal Integration
- (2017) Nafisa M. Hassan et al. Scientific Reports
- Improving In Vivo Efficacy of Bioactive Molecules: An Overview of Potentially Antitumor Phytochemicals and Currently Available Lipid-Based Delivery Systems
- (2017) Lamia Mouhid et al. Journal of Oncology
- Inhibition of Pyruvate Kinase M2 Markedly Reduces Chemoresistance of Advanced Bladder Cancer to Cisplatin
- (2017) Xing Wang et al. Scientific Reports
- PKM2 promotes cell migration and inhibits autophagy by mediating PI3K/AKT activation and contributes to the malignant development of gastric cancer
- (2017) Chao Wang et al. Scientific Reports
- Resveratrol Induces Cancer Cell Apoptosis through MiR-326/PKM2-Mediated ER Stress and Mitochondrial Fission
- (2016) Haili Wu et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Overview of Oroxylin A: A Promising Flavonoid Compound
- (2016) Lu Lu et al. PHYTOTHERAPY RESEARCH
- Cinnamaldehydes in Cancer Chemotherapy
- (2016) Su-Hyung Hong et al. PHYTOTHERAPY RESEARCH
- Nanocarriers for the delivery of active ingredients and fractions extracted from natural products used in traditional Chinese medicine (TCM)
- (2015) Ying Liu et al. ADVANCES IN COLLOID AND INTERFACE SCIENCE
- Secreted pyruvate kinase M2 facilitates cell migration via PI3K/Akt and Wnt/β-catenin pathway in colon cancer cells
- (2015) Peng Yang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Glucose-deprivation increases thyroid cancer cells sensitivity to metformin
- (2015) Athanasios Bikas et al. ENDOCRINE-RELATED CANCER
- Anticancer activity of pyrithione zinc in oral cancer cells identified in small molecule screens and xenograft model: Implications for oral cancer therapy
- (2015) Gunjan Srivastava et al. Molecular Oncology
- Metformin Induces Apoptosis and Downregulates Pyruvate Kinase M2 in Breast Cancer Cells Only When Grown in Nutrient-Poor Conditions
- (2015) Alessandra Silvestri et al. PLoS One
- Pantoprazole inhibits human gastric adenocarcinoma SGC-7901 cells by downregulating the expression of pyruvate kinase M2
- (2015) YONGHUA SHEN et al. Oncology Letters
- Lichen Secondary Metabolite, Physciosporin, Inhibits Lung Cancer Cell Motility
- (2015) Yi Yang et al. PLoS One
- The Diagnostic Accuracy of the M2 Pyruvate Kinase Quick Stool Test- A Rapid Office Based Assay Test for the Detection of Colorectal Cancer
- (2015) Suresh Sithambaram et al. PLoS One
- Pyruvate kinase M2 regulates glucose metabolism by functioning as a coactivator for hypoxia-inducible factor 1 in cancer cells
- (2015) Weibo Luo et al. Oncotarget
- No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis
- (2015) Katharina Bluemlein et al. Oncotarget
- The multifaceted regulation and functions of PKM2 in tumor progression
- (2014) Zongwei Li et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Pyruvate kinase M2 facilitates colon cancer cell migration via the modulation of STAT3 signalling
- (2014) Peng Yang et al. CELLULAR SIGNALLING
- Ginsenoside 20(S)-Rg3 inhibits the Warburg effect through STAT3 pathways in ovarian cancer cells
- (2014) JIE LI et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Pyruvate Kinase M2 in Blood Circulation Facilitates Tumor Growth by Promoting Angiogenesis
- (2014) Liangwei Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Chemopreventive and Therapeutic Potential of “Naringenin,” a Flavanone Present in Citrus Fruits
- (2014) Irfan Ahmad Mir et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Sensitizing the Therapeutic Efficacy of Taxol with Shikonin in Human Breast Cancer Cells
- (2014) Wenjuan Li et al. PLoS One
- Synergistic Combination of Gemcitabine and Dietary Molecule Induces Apoptosis in Pancreatic Cancer Cells and Down Regulates PKM2 Expression
- (2014) Archana Pandita et al. PLoS One
- Role of pyruvate kinase M2 in transcriptional regulation leading to epithelial-mesenchymal transition
- (2014) A. Hamabe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Control of glioma cell death and differentiation by PKM2–Oct4 interaction
- (2014) M Morfouace et al. Cell Death & Disease
- Mini-review on Glycolysis and Cancer
- (2013) M. Akram JOURNAL OF CANCER EDUCATION
- Gliotoxin Isolated from Marine Fungus Aspergillus sp. Induces Apoptosis of Human Cervical Cancer and Chondrosarcoma Cells
- (2013) Van-Tinh Nguyen et al. Marine Drugs
- Allosteric Regulation of PKM2 Allows Cellular Adaptation to Different Physiological States
- (2013) D. Y. Gui et al. Science Signaling
- Gliotoxin is a potent NOTCH2 transactivation inhibitor and efficiently induces apoptosis in chronic lymphocytic leukaemia (CLL) cells
- (2012) Rainer Hubmann et al. BRITISH JOURNAL OF HAEMATOLOGY
- PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis
- (2012) Weiwei Yang et al. CELL
- Cyclosporine A inhibits breast cancer cell growth by downregulating the expression of pyruvate kinase subtype M2
- (2012) KAI JIANG et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Pyruvate Kinase M2 Regulates Gene Transcription by Acting as a Protein Kinase
- (2012) Xueliang Gao et al. MOLECULAR CELL
- Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
- (2012) Dimitrios Anastasiou et al. Nature Chemical Biology
- Resveratrol Inhibits Cancer Cell Metabolism by Down Regulating Pyruvate Kinase M2 via Inhibition of Mammalian Target of Rapamycin
- (2012) Mohd Askandar Iqbal et al. PLoS One
- M2 isoform of pyruvate kinase is dispensable for tumor maintenance and growth
- (2012) M. Cortes-Cros et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Additively Enhanced Antiproliferative Effect of Interferon Combined with Proanthocyanidin on Bladder Cancer Cells
- (2012) Andrew I. Fishman et al. Journal of Cancer
- Antineoplastic activity of ouabain and pyrithione zinc in acute myeloid leukemia
- (2011) M Tailler et al. ONCOGENE
- Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses
- (2011) D. Anastasiou et al. SCIENCE
- Evaluation of thieno[3,2-b]pyrrole[3,2-d]pyridazinones as activators of the tumor cell specific M2 isoform of pyruvate kinase
- (2010) Jian-kang Jiang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Combinatorial effects of thymoquinone on the anti-cancer activity of doxorubicin
- (2010) Katharina Effenberger-Neidnicht et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Inhibitors of Lactate Dehydrogenase Isoforms and their Therapeutic Potentials
- (2010) C. Granchi et al. CURRENT MEDICINAL CHEMISTRY
- Pyruvate kinase type M2: A key regulator of the metabolic budget system in tumor cells
- (2010) Sybille Mazurek INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Human pyruvate kinase M2: A multifunctional protein
- (2010) Vibhor Gupta et al. PROTEIN SCIENCE
- OSU-A9, a potent indole-3-carbinol derivative, suppresses breast tumor growth by targeting the Akt-NF- B pathway and stress response signaling
- (2009) J.-R. Weng et al. CARCINOGENESIS
- HIF-1: upstream and downstream of cancer metabolism
- (2009) Gregg L Semenza CURRENT OPINION IN GENETICS & DEVELOPMENT
- Evaluation of SubstitutedN,N′-Diarylsulfonamides as Activators of the Tumor Cell Specific M2 Isoform of Pyruvate Kinase
- (2009) Matthew B. Boxer et al. JOURNAL OF MEDICINAL CHEMISTRY
- Cranberry and Grape Seed Extracts Inhibit the Proliferative Phenotype of Oral Squamous Cell Carcinomas
- (2008) Kourt Chatelain et al. Evidence-based Complementary and Alternative Medicine
- Safety and nutritional assessment of GM plants and derived food and feed: The role of animal feeding trials
- (2008) FOOD AND CHEMICAL TOXICOLOGY
- In vitroAntitumor Mechanisms of VariousScutellariaExtracts and Constituent Flavonoids
- (2008) Prahlad Parajuli et al. PLANTA MEDICA
- Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription
- (2007) Jungwoon Lee et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Apigenin inhibits HGF-promoted invasive growth and metastasis involving blocking PI3K/Akt pathway and β4 integrin function in MDA-MB-231 breast cancer cells
- (2007) Wei-Jiunn Lee et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now