标题
Malic Enzyme 2 as a Potential Therapeutic Drug Target for Cancer
作者
关键词
-
出版物
IUBMB LIFE
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2018-08-30
DOI
10.1002/iub.1930
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeting Glutamine Metabolism for Cancer Treatment
- (2018) Yeon-Kyung Choi et al. Biomolecules & Therapeutics
- Metabolic reprogramming in the tumour microenvironment: a hallmark shared by cancer cells and T lymphocytes
- (2017) Katrina E. Allison et al. IMMUNOLOGY
- Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer
- (2017) Prasenjit Dey et al. NATURE
- Inhibition of malic enzyme 1 disrupts cellular metabolism and leads to vulnerability in cancer cells in glucose-restricted conditions
- (2017) S Murai et al. Oncogenesis
- Teaching the basics of cancer metabolism: Developing antitumor strategies by exploiting the differences between normal and cancer cell metabolism
- (2017) Balaraman Kalyanaraman Redox Biology
- Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015
- (2017) et al. JAMA Oncology
- Expression of Malic Enzymes in Sebaceous Lesions
- (2016) Ting-Fu Su et al. AMERICAN JOURNAL OF DERMATOPATHOLOGY
- Mitochondrial pyruvate carrier function and cancer metabolism
- (2016) Adam J Rauckhorst et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer
- (2016) Yujun Hao et al. Nature Communications
- Mitochondrial dysfunctions in cancer: Genetic defects and oncogenic signaling impinging on TCA cycle activity
- (2015) Enrico Desideri et al. CANCER LETTERS
- The AMP-activated protein kinase (AMPK) and cancer: Many faces of a metabolic regulator
- (2015) Brandon Faubert et al. CANCER LETTERS
- TRAF6-Mediated SM22α K21 Ubiquitination Promotes G6PD Activation and NADPH Production, Contributing to GSH Homeostasis and VSMC Survival In Vitro and In VivoNovelty and Significance
- (2015) Li-Hua Dong et al. CIRCULATION RESEARCH
- Human Mitochondrial NAD(P) + –Dependent Malic Enzyme Participates in Cutaneous Melanoma Progression and Invasion
- (2015) Yung-Lung Chang et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Cancer metabolism and the Warburg effect: the role of HIF-1 and PI3K
- (2015) Rupert Courtnay et al. MOLECULAR BIOLOGY REPORTS
- 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1–AMPK signalling
- (2015) Ruiting Lin et al. NATURE CELL BIOLOGY
- Metabolic reprogramming in cancer cells: glycolysis, glutaminolysis, and Bcl-2 proteins as novel therapeutic targets for cancer
- (2015) Chunxia Li et al. World Journal of Surgical Oncology
- Cellular senescence: a hitchhiker’s guide
- (2015) Aloysious Aravinthan Human Cell
- A small-molecule inhibitor suppresses the tumor-associated mitochondrial NAD(P)+-dependent malic enzyme (ME2) and induces cellular senescence
- (2015) Ju-Yi Hsieh et al. Oncotarget
- Review of aerobic glycolysis and its key enzymes - new targets for lung cancer therapy
- (2015) Xue-bing Li et al. Thoracic Cancer
- Warburg Effect or Reverse Warburg Effect? A Review of Cancer Metabolism
- (2015) Xiao Dong Xu et al. Oncology Research and Treatment
- Discovery of a novel inhibitor of NAD(P)+-dependent malic enzyme (ME2) by high-throughput screening
- (2014) Yi Wen et al. ACTA PHARMACOLOGICA SINICA
- Tumor bioenergetics: An emerging avenue for cancer metabolism targeted therapy
- (2014) Hyun Jung Kee et al. BMB Reports
- Cellular senescence and its effector programs
- (2014) R. Salama et al. GENES & DEVELOPMENT
- Serine and glycine metabolism in cancer
- (2014) Ivano Amelio et al. TRENDS IN BIOCHEMICAL SCIENCES
- The pentose phosphate pathway and cancer
- (2014) Krushna C. Patra et al. TRENDS IN BIOCHEMICAL SCIENCES
- Knockdown of Malic Enzyme 2 Suppresses Lung Tumor Growth, Induces Differentiation and Impacts PI3K/AKT Signaling
- (2014) Jian-Guo Ren et al. Scientific Reports
- Targeting glucose metabolism in patients with cancer
- (2013) Shannon E. Elf et al. CANCER
- The Emerging "Hallmarks" of Metabolic Reprogramming and Immune Evasion: Distinct or Linked?
- (2013) I. Kareva et al. CANCER RESEARCH
- Autophagy regulation by nutrient signaling
- (2013) Ryan C Russell et al. CELL RESEARCH
- Glutamine and cancer: cell biology, physiology, and clinical opportunities
- (2013) Christopher T. Hensley et al. JOURNAL OF CLINICAL INVESTIGATION
- Which way does the citric acid cycle turn during hypoxia? The critical role of α-ketoglutarate dehydrogenase complex
- (2013) Christos Chinopoulos JOURNAL OF NEUROSCIENCE RESEARCH
- Tumor glycolysis as a target for cancer therapy: progress and prospects
- (2013) Shanmugasundaram Ganapathy-Kanniappan et al. Molecular Cancer
- Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence
- (2013) Peng Jiang et al. NATURE
- Senescence and aging: the critical roles of p53
- (2013) A Rufini et al. ONCOGENE
- Metabolic reprogramming in cancer: Unraveling the role of glutamine in tumorigenesis
- (2012) Dania Daye et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Global cancer statistics
- (2011) Ahmedin Jemal et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Isocitrate dehydrogenase mutations in gliomas
- (2011) Changcun Guo et al. CURRENT OPINION IN NEUROLOGY
- Targeting cancer metabolism: a therapeutic window opens
- (2011) Matthew G. Vander Heiden NATURE REVIEWS DRUG DISCOVERY
- Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration
- (2011) Chris Jopling et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Revisiting the TCA cycle: signaling to tumor formation
- (2011) Nuno Raimundo et al. TRENDS IN MOLECULAR MEDICINE
- Induction of Erythroid Differentiation in Human Erythroleukemia Cells by Depletion of Malic Enzyme 2
- (2010) Jian-Guo Ren et al. PLoS One
- Mitochondrial malic enzyme (ME2) in pancreatic islets of the human, rat and mouse and clonal insulinoma cells
- (2009) Michael J. MacDonald et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Glutamine as indispensable nutrient in oncology: experimental and clinical evidence
- (2009) Katharina S. Kuhn et al. EUROPEAN JOURNAL OF NUTRITION
- Nuclear translocation of active AKT is required for erythroid differentiation in erythropoietin treated K562 erythroleukemia cells
- (2008) Silvia Missiroli et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Metabolic and Hemodynamic Events after Changes in Neuronal Activity: Current Hypotheses, Theoretical Predictions and in vivo NMR Experimental Findings
- (2008) Silvia Mangia et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Differential Contribution of the Gata1 Gene Hematopoietic Enhancer to Erythroid Differentiation
- (2008) M. Suzuki et al. MOLECULAR AND CELLULAR BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search