Redox-sensitive cyclophilin A elicits chemoresistance through realigning cellular oxidative status in colorectal cancer

Genomic evolution and diverse models of systemic metastases in colorectal cancer

(2021) Hai-Ning Chen et al.   GUT

A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging

(2020) Haopeng Xiao et al.   CELL

ROS induced p53 activation: DNA damage, redox signaling or both?

(2020) Tao Shi et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidative Stress in Cancer

(2020) John D. Hayes et al.   CANCER CELL

Bone Marrow Mesenchymal Stem Cells Support Acute Myeloid Leukemia Bioenergetics and Enhance Antioxidant Defense and Escape from Chemotherapy

(2020) Dorian Forte et al.   Cell Metabolism

Measurement of tumor antioxidant capacity and prediction of chemotherapy resistance in preclinical models of ovarian cancer by positron emission tomography

(2019) Hannah E Greenwood et al.   CLINICAL CANCER RESEARCH

Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma

(2019) Jingwen Jiang et al.   Autophagy

Exosomal cyclophilin A as a novel noninvasive biomarker for Epstein‐Barr virus associated nasopharyngeal carcinoma

(2019) Lingzhi Liu et al.   Cancer Medicine

PDLIM1 inhibits tumor metastasis through activating Hippo signaling in hepatocellular carcinoma

(2019) Zhao Huang et al.   HEPATOLOGY

Colorectal cancer

(2019) Evelien Dekker et al.   LANCET

Inhibition of MDR1 Overcomes Resistance to Brentuximab Vedotin in Hodgkin Lymphoma

(2019) Robert Chen et al.   CLINICAL CANCER RESEARCH

Glutathione metabolism in cancer progression and treatment resistance

(2018) Ankita Bansal et al.   JOURNAL OF CELL BIOLOGY

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Phase Ib Results of the Rational Combination of Selumetinib and Cyclosporin A in Advanced Solid Tumors with an Expansion Cohort in Metastatic Colorectal Cancer

(2018) Anuradha Krishnamurthy et al.   CANCER RESEARCH

ChEMBL: towards direct deposition of bioassay data

(2018) David Mendez et al.   NUCLEIC ACIDS RESEARCH

ROS and the DNA damage response in cancer

(2018) Upadhyayula Sai Srinivas et al.   Redox Biology

Colon Cancer, Version 1.2017, NCCN Clinical Practice Guidelines in Oncology

(2017) Al B. Benson et al.   Journal of the National Comprehensive Cancer Network

Targeting the Thioredoxin System for Cancer Therapy

(2017) Junmin Zhang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Oxidative Stress in COPD: Sources, Markers, and Potential Mechanisms

(2017) Adam McGuinness et al.   Journal of Clinical Medicine

The Tumorigenic Roles of the Cellular REDOX Regulatory Systems

(2016) Stéphanie Anaís Castaldo et al.   Oxidative Medicine and Cellular Longevity

The Dual Roles of NRF2 in Cancer

(2016) Silvia Menegon et al.   TRENDS IN MOLECULAR MEDICINE

Annexin A2 is a novel Cellular Redox Regulatory Protein involved in Tumorigenesis

(2015) Patricia Alexandra Madureira et al.   Oncotarget

Acetylation of cyclophilin A is required for its secretion and vascular cell activation

(2013) Nwe Nwe Soe et al.   CARDIOVASCULAR RESEARCH

Cyclophilin A: a key player for human disease

(2013) P Nigro et al.   Cell Death & Disease

Metabolic regulation of oxygen and redox homeostasis by p53: Lessons from evolutionary biology?

(2012) Jie Zhuang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linking

(2011) Todd J Cohen et al.   EMBO JOURNAL

Peroxiredoxin II Is an Essential Antioxidant Enzyme that Prevents the Oxidative Inactivation of VEGF Receptor-2 in Vascular Endothelial Cells

(2011) Dong Hoon Kang et al.   MOLECULAR CELL

Glutathione peroxidase-deficient smooth muscle cells cause paracrine activation of normal smooth muscle cells via cyclophilin A

(2011) Maysam Takapoo et al.   VASCULAR PHARMACOLOGY

Stress-Responsive Sestrins Link p53 with Redox Regulation and Mammalian Target of Rapamycin Signaling

(2010) Andrei V. Budanov   ANTIOXIDANTS & REDOX SIGNALING

Erlotinib Combined with Cyclosporine in a Liver-Transplant Recipient with Epidermal Growth Factor Receptor-Mutated Non-small Cell Lung Cancer

(2010) Tommaso De Pas et al.   Journal of Thoracic Oncology

The Antioxidant Enzyme Prdx1 Controls Neuronal Differentiation by Thiol-Redox-Dependent Activation of GDE2

(2009) Ye Yan et al.   CELL

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

The prolyl cis/trans isomerase cyclophilin 18 interacts with the tumor suppressor p53 and modifies its functions in cell cycle regulation and apoptosis

(2009) N Baum et al.   ONCOGENE

Proteomics Identification of Cyclophilin A as a Potential Prognostic Factor and Therapeutic Target in Endometrial Carcinoma

(2008) Zhengyu Li et al.   MOLECULAR & CELLULAR PROTEOMICS