Lapachol and lapachone analogs: a journey of two decades of patent research(1997-2016)

Structure-activity relationship (SAR) study and design strategies of nitrogen-containing heterocyclic moieties for their anticancer activities

(2017) Jawaid Akhtar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Preclinical Pharmacokinetic Evaluation of β-Lapachone: Characteristics of Oral Bioavailability and First-Pass Metabolism in Rats

(2015) Iksoo Kim et al.   Biomolecules & Therapeutics

Heterocyclic Anticancer Compounds: Recent Advances and the Paradigm Shift towards the Use of Nanomedicine’s Tool Box

(2015) Pedro Martins et al.   MOLECULES

Evidences for leishmanicidal activity of the naphthoquinone derivative epoxy-α-lapachone

(2014) Franklin Souza-Silva et al.   EXPERIMENTAL PARASITOLOGY

Growth inhibitory activity for cancer cell lines of lapachol and its natural and semi-synthetic derivatives

(2013) Serena Fiorito et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Lapachol and its congeners as anticancer agents: a review

(2013) Francesco Epifano et al.   PHYTOCHEMISTRY REVIEWS

Antifungal activity of the naphthoquinone beta-lapachone against disseminated infection with Cryptococcus neoformans var. neoformans in dexamethasone-immunosuppressed Swiss mice

(2010) C.S. Medeiros et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Synthesis and evaluation of quinonoid compounds against tumor cell lines

(2010) Eufrânio N. da Silva et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cisplatin enhances the anticancer effect of β-lapachone by upregulating NQO1

(2009) Kaoru Terai et al.   ANTI-CANCER DRUGS

Red Lapacho (Tabebuia impetiginosa)—A global ethnopharmacological commodity?

(2008) J. Rubén Gómez Castellanos et al.   JOURNAL OF ETHNOPHARMACOLOGY