标题
Role of ceramide/sphingomyelin (SM) balance regulated through “SM cycle” in cancer
作者
关键词
Sphingomyelin, Ceramide, SM cycle, Sphingomyelin synthase, Sphingomyelinase, Cancer
出版物
CELLULAR SIGNALLING
Volume 87, Issue -, Pages 110119
出版商
Elsevier BV
发表日期
2021-08-19
DOI
10.1016/j.cellsig.2021.110119
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death
- (2021) Nina Meyer et al. Autophagy
- Acid sphingomyelinase-dependent autophagic degradation of GPX4 is critical for the execution of ferroptosis
- (2021) Faisal Thayyullathil et al. Cell Death & Disease
- Neutral Sphingomyelinase 2 Heightens Anti-Melanoma Immune Responses and Anti–PD-1 Therapy Efficacy
- (2021) Anne Montfort et al. Cancer Immunology Research
- Deficiency of sphingomyelin synthase 2 prolongs survival by the inhibition of lymphoma infiltration through ICAM‐1 reduction
- (2020) Makoto Taniguchi et al. FASEB JOURNAL
- Fusion of lysosomes to plasma membrane initiates radiation-induced apoptosis
- (2020) Charles S. Ferranti et al. JOURNAL OF CELL BIOLOGY
- Lipid rafts as signaling hubs in cancer cell survival/death and invasion: implications in tumor progression and therapy
- (2020) Faustino Mollinedo et al. JOURNAL OF LIPID RESEARCH
- Sphingomyelin phosphodiesterase 3 methylation and silencing in oral squamous cell carcinoma results in increased migration and invasion and altered stress response
- (2020) James Jabalee et al. Oncotarget
- Potential therapeutic target for aging and age-related neurodegenerative diseases: the role of acid sphingomyelinase
- (2020) Min Hee Park et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Ceramide launches an acute anti‐adhesion pro‐migration cell signaling program in response to chemotherapy
- (2020) Daniel Canals et al. FASEB JOURNAL
- Antiproliferative Effects of Thymoquinone in MCF-7 Breast and HepG2 Liver Cancer Cells: Possible Role of Ceramide and ER Stress
- (2020) Mutay Aslan et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Neutral sphingomyelinase 2 regulates inflammatory responses in monocytes/macrophages induced by TNF-α
- (2020) Fatema Al-Rashed et al. Scientific Reports
- Overriding sorafenib resistance via blocking lipid metabolism and Ras by sphingomyelin synthase 1 inhibition in hepatocellular carcinoma
- (2020) Haofeng Lu et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Role of sphingomyelin on the interaction of the anticancer drug gemcitabine hydrochloride with cell membrane models
- (2020) Elsa M. Materon et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- The Opposing Contribution of SMS1 and SMS2 to Glioma Progression and Their Value in the Therapeutic Response to 2OHOA
- (2019) Paula Fernández-García et al. Cancers
- Sphingomyelin synthase 2 promotes an aggressive breast cancer phenotype by disrupting the homoeostasis of ceramide and sphingomyelin
- (2019) Kehong Zheng et al. Cell Death & Disease
- Advances in determining signaling mechanisms of ceramide and role in disease
- (2019) Jeffrey L. Stith et al. JOURNAL OF LIPID RESEARCH
- Sphingolipid/Ceramide Pathways and Autophagy in the Onset and Progression of Melanoma: Novel Therapeutic Targets and Opportunities
- (2019) Michele Lai et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Sphingomyelin Synthase 2 Inhibition Ameliorates Cerebral Ischemic Reperfusion Injury Through Reducing the Recruitment of Toll‐Like Receptor 4 to Lipid Rafts
- (2019) Jing Xue et al. Journal of the American Heart Association
- The Physical Properties of Ceramides in Membranes
- (2018) Alicia Alonso et al. Annual Review of Biophysics
- Sphingomyelin in microdomains of the plasma membrane regulates amino acid-stimulated mTOR signal activation
- (2018) Kota Zama et al. CELL BIOLOGY INTERNATIONAL
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
- (2018) Lorenzo Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- Beyond the "Lock and Key" Paradigm: Targeting Lipid Rafts to Induce the Selective Apoptosis of Cancer Cells
- (2018) Anna Carolina Schneider Alves et al. CURRENT MEDICINAL CHEMISTRY
- Bcr-Abl regulation of sphingomyelin synthase 1 reveals a novel oncogenic-driven mechanism of protein up-regulation
- (2018) Sitapriya Moorthi et al. FASEB JOURNAL
- Antidepressants act by inducing autophagy controlled by sphingomyelin–ceramide
- (2018) Anne Gulbins et al. MOLECULAR PSYCHIATRY
- Loperamide, pimozide, and STF-62247 trigger autophagy-dependent cell death in glioblastoma cells
- (2018) Svenja Zielke et al. Cell Death & Disease
- Mechanisms that minimize retinal impact of apolipoprotein E absence
- (2018) Aicha Saadane et al. JOURNAL OF LIPID RESEARCH
- Sphingomyelin synthase 2 deficiency inhibits the induction of murine colitis-associated colon cancer
- (2017) Toshio Ohnishi et al. FASEB JOURNAL
- Ceramide Nanoliposomes as a MLKL-Dependent, Necroptosis-Inducing, Chemotherapeutic Reagent in Ovarian Cancer
- (2017) Xuewei Zhang et al. MOLECULAR CANCER THERAPEUTICS
- Identification and functional analysis of the risk microRNAs associated with cerebral low-grade glioma prognosis
- (2017) Xinrui Liu et al. Molecular Medicine Reports
- Sphingolipids and their metabolism in physiology and disease
- (2017) Yusuf A. Hannun et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Detectors for evaluating the cellular landscape of sphingomyelin- and cholesterol-rich membrane domains
- (2016) Takuma Kishimoto et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Inhibitors of the sphingomyelin cycle: Sphingomyelin synthases and sphingomyelinases
- (2016) Mohamad Adada et al. CHEMISTRY AND PHYSICS OF LIPIDS
- Comparative lipid analysis in the normal and cancerous organoids of MDCK cells
- (2016) Hisayoshi Yoshizaki et al. JOURNAL OF BIOCHEMISTRY
- Inhibition of Acid Sphingomyelinase Allows for Selective Targeting of CD4+Conventional versus Foxp3+Regulatory T Cells
- (2016) Claudia Hollmann et al. JOURNAL OF IMMUNOLOGY
- Inhibition of sphingomyelin synthase 1 affects ceramide accumulation and hydrogen peroxide-induced apoptosis in Neuro-2a cells
- (2016) Ranran Tu et al. NEUROREPORT
- Sphingomyelin generated by sphingomyelin synthase 1 is involved in attachment and infection with Japanese encephalitis virus
- (2016) Makoto Taniguchi et al. Scientific Reports
- Visualization of Lipid Membrane Reorganization Induced by a Pore-Forming Toxin Using High-Speed Atomic Force Microscopy
- (2015) Neval Yilmaz et al. ACS Nano
- Critical determinants of mitochondria-associated neutral sphingomyelinase (MA-nSMase) for mitochondrial localization
- (2015) Vinodh Rajagopalan et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Dihydroceramide desaturase 1, the gatekeeper of ceramide induced lipotoxicity
- (2015) S. Rodriguez-Cuenca et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- The traditional Tibetan medicine Yukyung Karne exhibits a potent anti-metastatic activity by inhibiting the epithelial to mesenchymal transition and cell migration
- (2015) Tenzin Choedon et al. BMC Complementary and Alternative Medicine
- All members in the sphingomyelin synthase gene family have ceramide phosphoethanolamine synthase activity
- (2015) Tingbo Ding et al. JOURNAL OF LIPID RESEARCH
- Ceramide metabolism regulates autophagy and apoptotic cell death induced by melatonin in liver cancer cells
- (2015) Raquel Ordoñez et al. JOURNAL OF PINEAL RESEARCH
- Differential changes in sphingolipids between TNF-induced necroptosis and apoptosis in U937 cells and necroptosis-resistant sublines
- (2015) Hirofumi Sawai et al. LEUKEMIA RESEARCH
- Sphingomyelin distribution in lipid rafts of artificial monolayer membranes visualized by Raman microscopy
- (2015) Jun Ando et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- P53-dependent upregulation of neutral sphingomyelinase-2: role in doxorubicin-induced growth arrest
- (2015) A A Shamseddine et al. Cell Death & Disease
- Lysosomal ceramide generated by acid sphingomyelinase triggers cytosolic cathepsin B-mediated degradation of X-linked inhibitor of apoptosis protein in natural killer/T lymphoma cell apoptosis
- (2015) M Taniguchi et al. Cell Death & Disease
- Alkaline sphingomyelinase (NPP7) promotes cholesterol absorption by affecting sphingomyelin levels in the gut: A study with NPP7 knockout mice
- (2014) Ping Zhang et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Enhanced Colonic Tumorigenesis in Alkaline Sphingomyelinase (NPP7) Knockout Mice
- (2014) Y. Chen et al. MOLECULAR CANCER THERAPEUTICS
- Sphingomyelin Synthase 1 Regulates Neuro-2a Cell Proliferation and Cell Cycle Progression Through Modulation of p27 Expression and Akt Signaling
- (2014) Umadevi V. Wesley et al. MOLECULAR NEUROBIOLOGY
- Sphingomyelin Synthase 2 Activity and Liver Steatosis
- (2013) Yue Li et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- The role of sphingomyelin and sphingomyelin synthases in cell death, proliferation and migration—from cell and animal models to human disorders
- (2013) Makoto Taniguchi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Clot retraction is mediated by factor XIII-dependent fibrin- IIb 3-myosin axis in platelet sphingomyelin-rich membrane rafts
- (2013) K. Kasahara et al. BLOOD
- Increased Oxidative Stress Impairs Adipose Tissue Function in Sphingomyelin Synthase 1 Null Mice
- (2013) Masato Yano et al. PLoS One
- Fingolimod attenuates ceramide-induced blood–brain barrier dysfunction in multiple sclerosis by targeting reactive astrocytes
- (2012) Ruben van Doorn et al. ACTA NEUROPATHOLOGICA
- Ordering of ceramide formation and caspase-9 activation in CD95L-induced Jurkat leukemia T cell apoptosis
- (2012) Elodie Lafont et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- CD4+ T-cell dysfunctions through the impaired lipid rafts ameliorate concanavalin A-induced hepatitis in sphingomyelin synthase 1-knockout mice
- (2012) L. Dong et al. INTERNATIONAL IMMUNOLOGY
- The Tricyclodecan-9-yl-xanthogenate D609 Triggers Ceramide Increase and Enhances FasL-Induced Caspase-Dependent and -Independent Cell Death in T Lymphocytes
- (2012) Delphine Milhas et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Regulation of Autophagy and Its Associated Cell Death by “Sphingolipid Rheostat”
- (2012) Makoto Taniguchi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Modulation of Ceramide Synthase Activity via Dimerization
- (2012) Elad L. Laviad et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sphingomyelin synthase 1 activity is regulated by theBCR-ABLoncogene
- (2012) Tara Ann Burns et al. JOURNAL OF LIPID RESEARCH
- Deficiency of sphingomyelin synthase-1 but not sphingomyelin synthase-2 causes hearing impairments in mice
- (2012) Mei-Hong Lu et al. JOURNAL OF PHYSIOLOGY-LONDON
- Regulation of Cell Migration by Sphingomyelin Synthases: Sphingomyelin in Lipid Rafts Decreases Responsiveness to Signaling by the CXCL12/CXCR4 Pathway
- (2012) S. Asano et al. MOLECULAR AND CELLULAR BIOLOGY
- Visualization of ceramide channels by transmission electron microscopy
- (2011) Soumya Samanta et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Membrane microdomain sphingolipids are required for anti-CD20-induced death of chronic lymphocytic leukemia B cells
- (2011) M. Hammadi et al. HAEMATOLOGICA
- Dynamic Modification of Sphingomyelin in Lipid Microdomains Controls Development of Obesity, Fatty Liver, and Type 2 Diabetes
- (2011) Susumu Mitsutake et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sphingomyelin Synthase 1-generated Sphingomyelin Plays an Important Role in Transferrin Trafficking and Cell Proliferation
- (2011) Abo Bakr Abdel Shakor et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Subcellular Targeting Domains of Sphingomyelin Synthase 1 and 2
- (2011) Calvin Yeang et al. Nutrition & Metabolism
- Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion
- (2011) R. D. Schreiber et al. SCIENCE
- Lysosomal Lipid Storage Diseases
- (2011) H. Schulze et al. Cold Spring Harbor Perspectives in Biology
- Transforming Growth Factor-β1 Induces Smad3-Dependent β1 Integrin Gene Expression in Epithelial-to-Mesenchymal Transition during Chronic Tubulointerstitial Fibrosis
- (2010) Yi-Chun Yeh et al. AMERICAN JOURNAL OF PATHOLOGY
- Sphingomyelin synthase 2 (SMS2) deficiency attenuates LPS-induced lung injury
- (2010) Satish Gowda et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Selective Reduction in the Sphingomyelin Content of Atherogenic Lipoproteins Inhibits Their Retention in Murine Aortas and the Subsequent Development of Atherosclerosis
- (2010) Yifan Fan et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Ceramide-rich platforms in transmembrane signaling
- (2010) Branka Stancevic et al. FEBS LETTERS
- Mitochondrial Dysfunction and Increased Reactive Oxygen Species Impair Insulin Secretion in Sphingomyelin Synthase 1-null Mice
- (2010) Masato Yano et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification and Characterization of Murine Mitochondria-associated Neutral Sphingomyelinase (MA-nSMase), the Mammalian Sphingomyelin Phosphodiesterase 5
- (2010) Bill X. Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Egg-Sphingomyelin and Cholesterol Form a Stoichiometric Molecular Complex in Bilayers of Egg-Phosphatidylcholine
- (2010) Peter J. Quinn et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Stress-Induced Sphingolipid Signaling: Role of Type-2 Neutral Sphingomyelinase in Murine Cell Apoptosis and Proliferation
- (2010) Raphael Devillard et al. PLoS One
- Fas/CD95 down-regulation in lymphoma cells through acquired alkyllysophospholipid resistance: partial role of associated sphingomyelin deficiency
- (2009) Wim J. van Blitterswijk et al. BIOCHEMICAL JOURNAL
- Roles and regulation of secretory and lysosomal acid sphingomyelinase
- (2009) Russell W. Jenkins et al. CELLULAR SIGNALLING
- Macrophage Sphingomyelin Synthase 2 Deficiency Decreases Atherosclerosis in Mice
- (2009) Jing Liu et al. CIRCULATION RESEARCH
- Sphingomyelin synthase-related protein SMSr controls ceramide homeostasis in the ER
- (2009) Ana M. Vacaru et al. JOURNAL OF CELL BIOLOGY
- Sphingomyelin synthase SMS2 displays dual activity as ceramide phosphoethanolamine synthase
- (2009) Philipp Ternes et al. JOURNAL OF LIPID RESEARCH
- Lysosomal ceramide mediates gemcitabine-induced death of glioma cells
- (2009) Claudia A. Dumitru et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities
- (2009) G. Han et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sphingomyelin Synthase 2 Deficiency Attenuates NFκB Activation
- (2008) Tiruneh K. Hailemariam et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Effects of ceramide and other simple sphingolipids on membrane lateral structure
- (2008) Félix M. Goñi et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- The domain responsible for sphingomyelin synthase (SMS) activity
- (2008) Calvin Yeang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Phase diagrams of lipid mixtures relevant to the study of membrane rafts
- (2008) Félix M. Goñi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Protein phosphatase 2A inactivates Bcl2's antiapoptotic function by dephosphorylation and up-regulation of Bcl2-p53 binding
- (2008) X. Deng et al. BLOOD
- Role of sphingosine kinases and lipid phosphate phosphatases in regulating spatial sphingosine 1-phosphate signalling in health and disease
- (2008) S PYNE et al. CELLULAR SIGNALLING
- Suppression of sphingomyelin synthase 1 by small interference RNA is associated with enhanced ceramide production and apoptosis after photodamage
- (2008) Duska Separovic et al. EXPERIMENTAL CELL RESEARCH
- Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling
- (2008) Archana Mukhopadhyay et al. FASEB JOURNAL
- Impaired TCR signaling through dysfunction of lipid rafts in sphingomyelin synthase 1 (SMS1)-knockdown T cells
- (2008) Z.-X. Jin et al. INTERNATIONAL IMMUNOLOGY
- Caspase‐3 enhances lung metastasis and cell migration in a protease‐independent mechanism through the ERK pathway
- (2008) Yu‐Jung Cheng et al. INTERNATIONAL JOURNAL OF CANCER
- Neutral Sphingomyelinase-3 Is a DNA Damage and Nongenotoxic Stress-Regulated Gene That Is Deregulated in Human Malignancies
- (2008) C. A. Corcoran et al. MOLECULAR CANCER RESEARCH
- Acid Sphingomyelinase Overexpression Enhances the Antineoplastic Effects of Irradiation In Vitro and In Vivo
- (2008) Eric L Smith et al. MOLECULAR THERAPY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started