标题
Metabolomics in cancer research and emerging applications in clinical oncology
作者
关键词
-
出版物
CA-A CANCER JOURNAL FOR CLINICIANS
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2021-05-13
DOI
10.3322/caac.21670
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Metabolomic profiling of rare cell populations isolated by flow cytometry from tissues
- (2021) Andrew W DeVilbiss et al. eLife
- MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer
- (2020) Jessica C. Casciano et al. BRITISH JOURNAL OF CANCER
- A prospective analysis of circulating plasma metabolites associated with ovarian cancer risk
- (2020) Oana A Zeleznik et al. CANCER RESEARCH
- Effect of a Behavioral Intervention to Increase Vegetable Consumption on Cancer Progression Among Men With Early-Stage Prostate Cancer
- (2020) J. Kellogg Parsons et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Mitochondrial TCA cycle metabolites control physiology and disease
- (2020) Inmaculada Martínez-Reyes et al. Nature Communications
- Salivary Metabolomics: From Diagnostic Biomarker Discovery to Investigating Biological Function
- (2020) Alexander Gardner et al. Metabolites
- Dietary modifications for enhanced cancer therapy
- (2020) Naama Kanarek et al. NATURE
- Metabolic reprogramming and cancer progression
- (2020) Brandon Faubert et al. SCIENCE
- Ribonucleotide Reductases: Structure, Chemistry, and Metabolism Suggest New Therapeutic Targets
- (2020) Brandon L. Greene et al. Annual Review of Biochemistry
- American Cancer Society guideline for diet and physical activity for cancer prevention
- (2020) Cheryl L. Rock et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Safety and efficacy of BAY1436032 in IDH1-mutant AML: phase I study results
- (2020) Michael Heuser et al. LEUKEMIA
- The Molecular Link from Diet to Cancer Cell Metabolism
- (2020) Shree Bose et al. MOLECULAR CELL
- Fast and sensitive flow-injection mass spectrometry metabolomics by analyzing sample-specific ion distributions
- (2020) Boris Sarvin et al. Nature Communications
- Fasting mimicking diet as an adjunct to neoadjuvant chemotherapy for breast cancer in the multicentre randomized phase 2 DIRECT trial
- (2020) Stefanie de Groot et al. Nature Communications
- Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition
- (2020) Bryan Ngo et al. Cancer Discovery
- Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma
- (2020) Allison N Lau et al. eLife
- Quantitative Analysis of the Physiological Contributions of Glucose to the TCA Cycle
- (2020) Shiyu Liu et al. Cell Metabolism
- HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice
- (2020) Rouven Hoefflin et al. Nature Communications
- Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity
- (2020) Alison E. Ringel et al. CELL
- Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector Treg Cells
- (2020) Wei Su et al. Cell Metabolism
- Increased demand for NAD+ relative to ATP drives aerobic glycolysis
- (2020) Alba Luengo et al. MOLECULAR CELL
- Efficacy and safety of the combination of metformin, everolimus and exemestane in overweight and obese postmenopausal patients with metastatic, hormone receptor-positive, HER2-negative breast cancer: a phase II study
- (2019) Clinton Yam et al. INVESTIGATIONAL NEW DRUGS
- High-fructose corn syrup enhances intestinal tumor growth in mice
- (2019) Marcus D. Goncalves et al. SCIENCE
- Identification of bioactive metabolites using activity metabolomics
- (2019) Markus M. Rinschen et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Prospective serum metabolomic profiling of lethal prostate cancer
- (2019) Jiaqi Huang et al. INTERNATIONAL JOURNAL OF CANCER
- Increased Serine Synthesis Provides an Advantage for Tumors Arising in Tissues Where Serine Levels Are Limiting
- (2019) Mark R. Sullivan et al. Cell Metabolism
- Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability
- (2019) Mark R Sullivan et al. eLife
- Dietary methionine influences therapy in mouse cancer models and alters human metabolism
- (2019) Xia Gao et al. NATURE
- The Metabolic Signature of Macrophage Responses
- (2019) Antonella Viola et al. Frontiers in Immunology
- Ketogenic diet in the treatment of cancer – Where do we stand?
- (2019) Daniela D. Weber et al. Molecular Metabolism
- Stearoyl-CoA Desaturase 1 as a Therapeutic Target for the Treatment of Cancer
- (2019) Zuzanna Tracz-Gaszewska et al. Cancers
- Translational Metabolomics: Current Challenges and Future Opportunities
- (2019) Farhana R. Pinu et al. Metabolites
- NMR Spectroscopy for Metabolomics Research
- (2019) Abdul-Hamid Emwas et al. Metabolites
- Prospective analysis of circulating metabolites and breast cancer in EPIC
- (2019) Mathilde His et al. BMC Medicine
- Post diagnosis loss of skeletal muscle, but not adipose tissue, is associated with shorter survival of patients with advanced pancreatic cancer
- (2019) Ana Babic et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- The MYC Oncogene Cooperates with Sterol-Regulated Element-Binding Protein to Regulate Lipogenesis Essential for Neoplastic Growth
- (2019) Arvin M. Gouw et al. Cell Metabolism
- The effects of chemotherapy on energy metabolic aspects in cancer patients: A systematic review
- (2019) Timia Van Soom et al. CLINICAL NUTRITION
- Safety and Efficacy of Mitapivat in Pyruvate Kinase Deficiency
- (2019) Rachael F. Grace et al. NEW ENGLAND JOURNAL OF MEDICINE
- Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion
- (2019) Robert D. Leone et al. SCIENCE
- Orally bioavailable glutamine antagonist prodrug JHU-083 penetrates mouse brain and suppresses the growth of MYC-driven medulloblastoma
- (2019) Allison R. Hanaford et al. Translational Oncology
- A novel therapeutic approach for anaplastic thyroid cancer through inhibition of LAT1
- (2019) Keisuke Enomoto et al. Scientific Reports
- A Variant of SLC1A5 Is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells
- (2019) Hee Chan Yoo et al. Cell Metabolism
- Plasma metabolites as possible biomarkers for diagnosis of breast cancer
- (2019) Jiwon Park et al. PLoS One
- TBK1 Is a Synthetic Lethal Target in Cancer with VHL Loss
- (2019) Lianxin Hu et al. Cancer Discovery
- Unraveling the Complex Interplay Between T Cell Metabolism and Function
- (2018) Ramon I. Klein Geltink et al. Annual Review of Immunology
- Inhibition of Glycolysis and Glutaminolysis: An Emerging Drug Discovery Approach to Combat Cancer
- (2018) Nicholas S. Akins et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Recent Development of Small Molecule Glutaminase Inhibitors
- (2018) Minsoo Song et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Endocrine Late Effects in Childhood Cancer Survivors
- (2018) Wassim Chemaitilly et al. JOURNAL OF CLINICAL ONCOLOGY
- Guidelines and considerations for the use of system suitability and quality control samples in mass spectrometry assays applied in untargeted clinical metabolomic studies
- (2018) David Broadhurst et al. Metabolomics
- A review of metabolism-associated biomarkers in lung cancer diagnosis and treatment
- (2018) Sanaya Bamji-Stocke et al. Metabolomics
- An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer
- (2018) Ming Chen et al. NATURE GENETICS
- An inhibitor of oxidative phosphorylation exploits cancer vulnerability
- (2018) Jennifer R. Molina et al. NATURE MEDICINE
- Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML
- (2018) Courtney D. DiNardo et al. NEW ENGLAND JOURNAL OF MEDICINE
- VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma
- (2018) Jing Zhang et al. SCIENCE
- Metabolomics analysis of human sweat collected after moderate exercise
- (2018) M.M. Delgado-Povedano et al. TALANTA
- Metabolic profiles of triple-negative and luminal A breast cancer subtypes in African-American identify key metabolic differences
- (2018) Fariba Tayyari et al. Oncotarget
- A systematic review on metabolomics-based diagnostic biomarker discovery and validation in pancreatic cancer
- (2018) Nguyen Phuoc Long et al. Metabolomics
- Altered exocrine function can drive adipose wasting in early pancreatic cancer
- (2018) Laura V. Danai et al. NATURE
- Histidine catabolism is a major determinant of methotrexate sensitivity
- (2018) Naama Kanarek et al. NATURE
- Metabolomics Biomarkers for Detection of Colorectal Neoplasms: A Systematic Review
- (2018) Vanessa Erben et al. Cancers
- Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism
- (2018) Marc O. Johnson et al. CELL
- The emergence of dihydroorotate dehydrogenase (DHODH) as a therapeutic target in acute myeloid leukemia
- (2018) David B. Sykes EXPERT OPINION ON THERAPEUTIC TARGETS
- Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade
- (2018) Ziming Wang et al. NATURE MEDICINE
- Inhibition of glucose metabolism selectively targets autoreactive follicular helper T cells
- (2018) Seung-Chul Choi et al. Nature Communications
- Ovarian Cancer Relies on Glucose Transporter 1 to Fuel Glycolysis and Growth: Anti-Tumor Activity of BAY-876
- (2018) Yibao Ma et al. Cancers
- Metabolic biomarker signature to differentiate pancreatic ductal adenocarcinoma from chronic pancreatitis
- (2017) Julia Mayerle et al. GUT
- How many cancer cases and deaths are potentially preventable? Estimates for Australia in 2013
- (2017) Louise F. Wilson et al. INTERNATIONAL JOURNAL OF CANCER
- Amino Acid Profiles of Serum and Urine in Search for Prostate Cancer Biomarkers: a Pilot Study
- (2017) Paweł Dereziński et al. International Journal of Medical Sciences
- Exploring cancer metabolism using stable isotope-resolved metabolomics (SIRM)
- (2017) Ronald C. Bruntz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Toxicity of Extended Adjuvant Therapy With Aromatase Inhibitors in Early Breast Cancer: A Systematic Review and Meta-analysis
- (2017) Hadar Goldvaser et al. JNCI-Journal of the National Cancer Institute
- Navigating freely-available software tools for metabolomics analysis
- (2017) Rachel Spicer et al. Metabolomics
- A relative quantitative positive/negative ion switching method for untargeted lipidomics via high resolution LC-MS/MS from any biological source
- (2017) Susanne B. Breitkopf et al. Metabolomics
- Metabolic Profiling in Formalin-Fixed and Paraffin-Embedded Prostate Cancer Tissues
- (2017) Stefano Cacciatore et al. MOLECULAR CANCER RESEARCH
- Metabolomic analysis based on 1H-nuclear magnetic resonance spectroscopy metabolic profiles in tuberculous, malignant and transudative pleural effusion
- (2017) Cheng Wang et al. Molecular Medicine Reports
- Modulating the therapeutic response of tumours to dietary serine and glycine starvation
- (2017) Oliver D. K. Maddocks et al. NATURE
- Glucose feeds the TCA cycle via circulating lactate
- (2017) Sheng Hui et al. NATURE
- The impact of cellular metabolism on chromatin dynamics and epigenetics
- (2017) Michael A. Reid et al. NATURE CELL BIOLOGY
- Metabolomics: A Primer
- (2017) Xiaojing Liu et al. TRENDS IN BIOCHEMICAL SCIENCES
- Metabolic Interactions in the Tumor Microenvironment
- (2017) Costas A. Lyssiotis et al. TRENDS IN CELL BIOLOGY
- Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism
- (2017) Douglas E. Biancur et al. Nature Communications
- Pancreatic Exocrine Insufficiency in Pancreatic Cancer
- (2017) Miroslav Vujasinovic et al. Nutrients
- Metabolomics for biomarker discovery in the diagnosis, prognosis, survival and recurrence of colorectal cancer: a systematic review
- (2017) Fan Zhang et al. Oncotarget
- Phosphorylation of TXNIP by AKT Mediates Acute Influx of Glucose in Response to Insulin
- (2017) Althea N. Waldhart et al. Cell Reports
- Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition
- (2017) Alexander Muir et al. eLife
- Toxicity of Extended Adjuvant Therapy With Aromatase Inhibitors in Early Breast Cancer: A Systematic Review and Meta-analysis
- (2017) Hadar Goldvaser et al. JNCI-Journal of the National Cancer Institute
- Taurine – a possible fingerprint biomarker in non-muscle invasive bladder cancer: A pilot study by 1H NMR spectroscopy
- (2017) Shatakshi Srivastava et al. Cancer Biomarkers
- Metabolomics reveals novel blood plasma biomarkers associated to the BRCA1-mutated phenotype of human breast cancer
- (2017) Bàrbara Roig et al. Scientific Reports
- Higher plasma levels of lysophosphatidylcholine 18:0 are related to a lower risk of common cancers in a prospective metabolomics study
- (2016) Tilman Kühn et al. BMC Medicine
- Targeting HIF2α in Clear-Cell Renal Cell Carcinoma
- (2016) Christopher J. Ricketts et al. CANCER CELL
- The fractions of cancer attributable to modifiable factors: A global review
- (2016) David C. Whiteman et al. Cancer Epidemiology
- Metabolic Heterogeneity in Human Lung Tumors
- (2016) Christopher T. Hensley et al. CELL
- Metformin Targets Central Carbon Metabolism and Reveals Mitochondrial Requirements in Human Cancers
- (2016) Xiaojing Liu et al. Cell Metabolism
- The Emerging Hallmarks of Cancer Metabolism
- (2016) Natalya N. Pavlova et al. Cell Metabolism
- Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer
- (2016) Shawn M. Davidson et al. Cell Metabolism
- Analysis of Kynurenine/Tryptophan ratio and expression of IDO1 and 2 mRNA in tumour tissue of cervical cancer patients
- (2016) Jayakumar Hascitha et al. CLINICAL BIOCHEMISTRY
- Recurrent prostate cancer detection with anti-3-[18F]FACBC PET/CT: comparison with CT
- (2016) Oluwaseun A. Odewole et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Cancer metabolism at a glance
- (2016) Alexei Vazquez et al. JOURNAL OF CELL SCIENCE
- Untargeted Metabolomics Strategies—Challenges and Emerging Directions
- (2016) Alexandra C. Schrimpe-Rutledge et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate
- (2016) Michael E Pacold et al. Nature Chemical Biology
- Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models
- (2016) Robert U Svensson et al. NATURE MEDICINE
- Diet, nutrition and cancer: past, present and future
- (2016) Susan T. Mayne et al. Nature Reviews Clinical Oncology
- Emerging applications of metabolomics in drug discovery and precision medicine
- (2016) David S. Wishart NATURE REVIEWS DRUG DISCOVERY
- Body Fatness and Cancer — Viewpoint of the IARC Working Group
- (2016) Béatrice Lauby-Secretan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers
- (2016) Edouard Mullarky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers
- (2016) J. R. Mayers et al. SCIENCE
- Tissue-specific and convergent metabolic transformation of cancer correlates with metastatic potential and patient survival
- (2016) Edoardo Gaude et al. Nature Communications
- Targeting Cancer Metabolism: Dietary and Pharmacologic Interventions
- (2016) C. Vernieri et al. Cancer Discovery
- Serum metabolomic profiling facilitates the non-invasive identification of metabolic biomarkers associated with the onset and progression of non-small cell lung cancer
- (2016) Leonor Puchades-Carrasco et al. Oncotarget
- Targeting ACLY sensitizes castration-resistant prostate cancer cells to AR antagonism by impinging on an ACLY-AMPK-AR feedback mechanism
- (2016) Supriya Shah et al. Oncotarget
- Non-targeted and targeted metabolomics approaches to diagnosing lung cancer and predicting patient prognosis
- (2016) Xiaoli Zhang et al. Oncotarget
- Fundamentals of cancer metabolism
- (2016) R. J. DeBerardinis et al. Science Advances
- Serum biomarkers of habitual coffee consumption may provide insight into the mechanism underlying the association between coffee consumption and colorectal cancer
- (2015) K. A. Guertin et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- MALDI mass spectrometric imaging meets “omics”: recent advances in the fruitful marriage
- (2015) A. C. Crecelius et al. ANALYST
- Progress in the development of fatty acid synthase inhibitors as anticancer targets
- (2015) Genevieve E. Mullen et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion
- (2015) Kensuke Tateishi et al. CANCER CELL
- SCD1 negatively regulates autophagy-induced cell death in human hepatocellular carcinoma through inactivation of the AMPK signaling pathway
- (2015) Guang-Ming Huang et al. CANCER LETTERS
- Metabolomic Markers of Altered Nucleotide Metabolism in Early Stage Adenocarcinoma
- (2015) W. R. Wikoff et al. Cancer Prevention Research
- Integrated, Step-Wise, Mass-Isotopomeric Flux Analysis of the TCA Cycle
- (2015) Tiago C. Alves et al. Cell Metabolism
- Metabolic Dependencies in RAS-Driven Cancers
- (2015) A. C. Kimmelman CLINICAL CANCER RESEARCH
- A roadmap for interpreting 13 C metabolite labeling patterns from cells
- (2015) Joerg M Buescher et al. CURRENT OPINION IN BIOTECHNOLOGY
- Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis
- (2015) Yan Xiang et al. JOURNAL OF CLINICAL INVESTIGATION
- Role of Physical Activity and Diet After Colorectal Cancer Diagnosis
- (2015) Erin L. Van Blarigan et al. JOURNAL OF CLINICAL ONCOLOGY
- Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H+ symporters
- (2015) Ibtissam Marchiq et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Urine metabolic fingerprinting using LC–MS and GC–MS reveals metabolite changes in prostate cancer: A pilot study
- (2015) Wiktoria Struck-Lewicka et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Hypoxia-inducible factors regulate T cell metabolism and function
- (2015) Anthony T. Phan et al. MOLECULAR IMMUNOLOGY
- Targeting mitochondria metabolism for cancer therapy
- (2015) Samuel E Weinberg et al. Nature Chemical Biology
- Metabolomics Biomarkers for Breast Cancer
- (2015) Ulrich L. G�nther PATHOBIOLOGY
- Metabolic consequences of oncogenic IDH mutations
- (2015) Seth J. Parker et al. PHARMACOLOGY & THERAPEUTICS
- Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo
- (2015) Sriram Venneti et al. Science Translational Medicine
- Pyruvate kinase: Function, regulation and role in cancer
- (2015) William J. Israelsen et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Inhibition of mutant IDH1 decreases D-2-HG levels without affecting tumorigenic properties of chondrosarcoma cell lines
- (2015) Johnny Suijker et al. Oncotarget
- A case control study of sarcosine as an early prostate cancer detection biomarker
- (2015) Donna P. Ankerst et al. BMC Urology
- Pathophysiology of anorexia in the cancer cachexia syndrome
- (2015) Chukwuemeka Charles Ezeoke et al. Journal of Cachexia Sarcopenia and Muscle
- Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine.
- (2015) Sevin Turcan et al. Oncotarget
- Chemical inhibition of acetyl-CoA carboxylase suppresses self-renewal growth of cancer stem cells
- (2015) Bruna Corominas-Faja et al. Oncotarget
- The Role of Sarcosine Metabolism in Prostate Cancer Progression
- (2015) Amjad P Khan et al. NEOPLASIA
- Body mass index and survival in women with breast cancer—systematic literature review and meta-analysis of 82 follow-up studies
- (2014) D. S. M. Chan et al. ANNALS OF ONCOLOGY
- PTEN
- (2014) Carolyn A. Worby et al. Annual Review of Biochemistry
- Targeting Metabolic Changes in Cancer: Novel Therapeutic Approaches
- (2014) Ekaterina Bobrovnikova-Marjon et al. Annual Review of Medicine
- Serine Deprivation Enhances Antineoplastic Activity of Biguanides
- (2014) S.-P. Gravel et al. CANCER RESEARCH
- NMR metabolomics of human lung tumours reveals distinct metabolic signatures for adenocarcinoma and squamous cell carcinoma
- (2014) Cláudia M. Rocha et al. CARCINOGENESIS
- Biomarkers of Coordinate Metabolic Reprogramming in Colorectal Tumors in Mice and Humans
- (2014) Soumen K. Manna et al. GASTROENTEROLOGY
- Glutamate enrichment as new diagnostic opportunity in breast cancer
- (2014) Jan Budczies et al. INTERNATIONAL JOURNAL OF CANCER
- Metabolomics provide new insights on lung cancer staging and discrimination from chronic obstructive pulmonary disease
- (2014) Stanislaw Deja et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Plasma Metabolite Biomarkers for the Detection of Pancreatic Cancer
- (2014) Guoxiang Xie et al. JOURNAL OF PROTEOME RESEARCH
- Antitumor Activity of the Glutaminase Inhibitor CB-839 in Triple-Negative Breast Cancer
- (2014) M. I. Gross et al. MOLECULAR CANCER THERAPEUTICS
- [18F](2S,4S)-4-(3-Fluoropropyl)glutamine as a Tumor Imaging Agent
- (2014) Zehui Wu et al. MOLECULAR PHARMACEUTICS
- Quantitative flux analysis reveals folate-dependent NADPH production
- (2014) Jing Fan et al. NATURE
- Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development
- (2014) Jared R Mayers et al. NATURE MEDICINE
- Preliminary evaluation of 1′-[18F]fluoroethyl-β-D-lactose ([18F]FEL) for detection of pancreatic cancer in nude mouse orthotopic xenografts
- (2014) Thiruvengadam Arumugam et al. NUCLEAR MEDICINE AND BIOLOGY
- Bladder Cancer Biomarker Discovery Using Global Metabolomic Profiling of Urine
- (2014) Bryan M. Wittmann et al. PLoS One
- Roles of Caloric Restriction, Ketogenic Diet and Intermittent Fasting during Initiation, Progression and Metastasis of Cancer in Animal Models: A Systematic Review and Meta-Analysis
- (2014) Mengmeng Lv et al. PLoS One
- Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment
- (2014) Daniel Ackerman et al. TRENDS IN CELL BIOLOGY
- Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step
- (2014) Alexander A Shestov et al. eLife
- Nutrition and physical activity influence on breast cancer incidence and outcome
- (2013) Rowan T. Chlebowski BREAST
- Stearoyl-CoA Desaturase 1 Is a Novel Molecular Therapeutic Target for Clear Cell Renal Cell Carcinoma
- (2013) C. A. von Roemeling et al. CLINICAL CANCER RESEARCH
- The Role of 11C-Choline and 18F-Fluorocholine Positron Emission Tomography (PET) and PET/CT in Prostate Cancer: A Systematic Review and Meta-analysis
- (2013) Martin H. Umbehr et al. EUROPEAN UROLOGY
- What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
- (2013) J.-A. Losman et al. GENES & DEVELOPMENT
- Akt Phosphorylates HK-II at Thr-473 and Increases Mitochondrial HK-II Association to Protect Cardiomyocytes
- (2013) David J. Roberts et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Detection of oncogenic IDH1 mutations using magnetic resonance spectroscopy of 2-hydroxyglutarate
- (2013) Ovidiu C. Andronesi et al. JOURNAL OF CLINICAL INVESTIGATION
- Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells
- (2013) Zhen Yang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- In Vitro and In Vivo Characterization of 2-Deoxy-2-18F-Fluoro-D-Mannose as a Tumor-Imaging Agent for PET
- (2013) S. Furumoto et al. JOURNAL OF NUCLEAR MEDICINE
- Metabolomics in cancer biomarker discovery: Current trends and future perspectives
- (2013) Emily G. Armitage et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Urinary Metabotyping of Bladder Cancer Using Two-Dimensional Gas Chromatography Time-of-Flight Mass Spectrometry
- (2013) Kishore Kumar Pasikanti et al. JOURNAL OF PROTEOME RESEARCH
- Pharmacologic Activation of PKM2 Slows Lung Tumor Xenograft Growth
- (2013) K. M. Parnell et al. MOLECULAR CANCER THERAPEUTICS
- Heterogeneity of tumor-induced gene expression changes in the human metabolic network
- (2013) Jie Hu et al. NATURE BIOTECHNOLOGY
- Metabolic targets for cancer therapy
- (2013) Lorenzo Galluzzi et al. NATURE REVIEWS DRUG DISCOVERY
- Results of Initial Low-Dose Computed Tomographic Screening for Lung Cancer
- (2013) NEW ENGLAND JOURNAL OF MEDICINE
- Control of glutamine metabolism by the tumor suppressor Rb
- (2013) M R Reynolds et al. ONCOGENE
- The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival in Mice with Systemic Metastatic Cancer
- (2013) Angela M. Poff et al. PLoS One
- (R)-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
- (2013) J.-A. Losman et al. SCIENCE
- An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells
- (2013) D. Rohle et al. SCIENCE
- Targeted Inhibition of Mutant IDH2 in Leukemia Cells Induces Cellular Differentiation
- (2013) F. Wang et al. SCIENCE
- Energy Balance and Metabolism After Cancer Treatment
- (2013) Emily S. Tonorezos et al. SEMINARS IN ONCOLOGY
- Oncogenic Isocitrate Dehydrogenase Mutations: Mechanisms, Models, and Clinical Opportunities
- (2013) R. A. Cairns et al. Cancer Discovery
- Prospective serial evaluation of 2-hydroxyglutarate, during treatment of newly diagnosed acute myeloid leukemia, to assess disease activity and therapeutic response
- (2012) A. T. Fathi et al. BLOOD
- High stearoyl-CoA desaturase 1 expression is associated with shorter survival in breast cancer patients
- (2012) Ashley M. Holder et al. BREAST CANCER RESEARCH AND TREATMENT
- A phase I dose-escalation trial of 2-deoxy-d-glucose alone or combined with docetaxel in patients with advanced solid tumors
- (2012) Luis E. Raez et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism
- (2012) Haoqiang Ying et al. CELL
- The Metabolic Profile of Tumors Depends on Both the Responsible Genetic Lesion and Tissue Type
- (2012) Mariia O. Yuneva et al. Cell Metabolism
- Targeting Cancer Metabolism
- (2012) B. A. Teicher et al. CLINICAL CANCER RESEARCH
- MR spectroscopic imaging: Principles and recent advances
- (2012) Stefan Posse et al. JOURNAL OF MAGNETIC RESONANCE IMAGING
- Metabolomic profiling of lung and prostate tumor tissues by capillary electrophoresis time-of-flight mass spectrometry
- (2012) Kenjiro Kami et al. Metabolomics
- Metabolomics of Human Cerebrospinal Fluid Identifies Signatures of Malignant Glioma
- (2012) Jason W. Locasale et al. MOLECULAR & CELLULAR PROTEOMICS
- A Small-Molecule Inhibitor of Glucose Transporter 1 Downregulates Glycolysis, Induces Cell-Cycle Arrest, and Inhibits Cancer Cell Growth In Vitro and In Vivo
- (2012) Y. Liu et al. MOLECULAR CANCER THERAPEUTICS
- How cancer metabolism is tuned for proliferation and vulnerable to disruption
- (2012) Almut Schulze et al. NATURE
- Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells
- (2012) Oliver D. K. Maddocks et al. NATURE
- Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
- (2012) Dimitrios Anastasiou et al. Nature Chemical Biology
- 2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas
- (2012) Changho Choi et al. NATURE MEDICINE
- Understanding the mechanisms and treatment options in cancer cachexia
- (2012) Kenneth Fearon et al. Nature Reviews Clinical Oncology
- HMDB 3.0—The Human Metabolome Database in 2013
- (2012) David S. Wishart et al. NUCLEIC ACIDS RESEARCH
- Dose-dependent effects of calorie restriction on gene expression, metabolism, and tumor progression are partially mediated by insulin-like growth factor-1
- (2012) Leticia M. Nogueira et al. Cancer Medicine
- Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
- (2011) Wei Xu et al. CANCER CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Metabolic diseases and cancer risk
- (2011) Malin H. Faulds et al. CURRENT OPINION IN ONCOLOGY
- The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis
- (2011) Charles E Massie et al. EMBO JOURNAL
- The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
- (2011) Rasheduzzaman Chowdhury et al. EMBO REPORTS
- The potential use of 2-[18F]fluoro-2-deoxy-D-galactose as a PET/CT tracer for detection of hepatocellular carcinoma
- (2011) Michael Sørensen et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation
- (2011) Ruoning Wang et al. IMMUNITY
- Physical Activity and Survival After Prostate Cancer Diagnosis in the Health Professionals Follow-Up Study
- (2011) Stacey A. Kenfield et al. JOURNAL OF CLINICAL ONCOLOGY
- Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
- (2011) R. D. Michalek et al. JOURNAL OF IMMUNOLOGY
- Non-redox-active lipoate derivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo
- (2011) Zuzana Zachar et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- PET Imaging of Glutaminolysis in Tumors by 18F-(2S,4R)4-Fluoroglutamine
- (2011) B. P. Lieberman et al. JOURNAL OF NUCLEAR MEDICINE
- Characterization of The Human Tear Metabolome by LC–MS/MS
- (2011) Liyan Chen et al. JOURNAL OF PROTEOME RESEARCH
- Urinary Metabolic Biomarkers of Hepatocellular Carcinoma in an Egyptian Population: A Validation Study
- (2011) Mohamed I. F. Shariff et al. JOURNAL OF PROTEOME RESEARCH
- Proteomic Analysis Reveals Warburg Effect and Anomalous Metabolism of Glutamine in Pancreatic Cancer Cells
- (2011) Weidong Zhou et al. JOURNAL OF PROTEOME RESEARCH
- Definition and classification of cancer cachexia: an international consensus
- (2011) Kenneth Fearon et al. LANCET ONCOLOGY
- Functional genomics reveal that the serine synthesis pathway is essential in breast cancer
- (2011) Richard Possemato et al. NATURE
- Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
- (2011) Jason W Locasale et al. NATURE GENETICS
- Targeting cancer metabolism: a therapeutic window opens
- (2011) Matthew G. Vander Heiden NATURE REVIEWS DRUG DISCOVERY
- Radiopharmacological evaluation of 6-deoxy-6-[18F]fluoro-d-fructose as a radiotracer for PET imaging of GLUT5 in breast cancer
- (2011) Melinda Wuest et al. NUCLEAR MEDICINE AND BIOLOGY
- Plasma Free Amino Acid Profiling of Five Types of Cancer Patients and Its Application for Early Detection
- (2011) Yohei Miyagi et al. PLoS One
- Tyrosine positron emission tomography and protein synthesis rate in pituitary adenoma: Different effects of surgery and radiation therapy
- (2011) Alfons C.M. van den Bergh et al. RADIOTHERAPY AND ONCOLOGY
- Metabolic Tumor Imaging Using Magnetic Resonance Spectroscopy
- (2011) Kristine Glunde et al. SEMINARS IN ONCOLOGY
- Metabolic sequelae associated with androgen deprivation therapy for prostate cancer
- (2011) Jason E Faris et al. Current Opinion in Endocrinology Diabetes and Obesity
- A Western-Type Diet Accelerates Tumor Progression in an Autochthonous Mouse Model of Prostate Cancer
- (2010) Gemma Llaverias et al. AMERICAN JOURNAL OF PATHOLOGY
- The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate
- (2010) Patrick S. Ward et al. CANCER CELL
- Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
- (2010) Maria E. Figueroa et al. CANCER CELL
- Fatty acid synthase as a potential therapeutic target in cancer
- (2010) Richard Flavin et al. Future Oncology
- Fatty Acid Metabolism in the Liver, Measured by Positron Emission Tomography, Is Increased in Obese Individuals
- (2010) Patricia Iozzo et al. GASTROENTEROLOGY
- Decrease in Membrane Phospholipid Unsaturation Induces Unfolded Protein Response
- (2010) Hiroyuki Ariyama et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Noninvasive Urinary Metabonomic Diagnosis of Human Bladder Cancer
- (2010) Kishore Kumar Pasikanti et al. JOURNAL OF PROTEOME RESEARCH
- Integrated Ionization Approach for RRLC−MS/MS-based Metabonomics: Finding Potential Biomarkers for Lung Cancer
- (2010) Zhuoling An et al. JOURNAL OF PROTEOME RESEARCH
- Serum and Urinary Metabonomic Study of Human Osteosarcoma
- (2010) Zhiyu Zhang et al. JOURNAL OF PROTEOME RESEARCH
- The metabolic syndrome in cancer survivors
- (2010) Esther C de Haas et al. LANCET ONCOLOGY
- Abrogation of De novo Lipogenesis by Stearoyl-CoA Desaturase 1 Inhibition Interferes with Oncogenic Signaling and Blocks Prostate Cancer Progression in Mice
- (2010) V. Fritz et al. MOLECULAR CANCER THERAPEUTICS
- Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1
- (2010) Katrin Düvel et al. MOLECULAR CELL
- Hypoxia-Inducible Factors and the Response to Hypoxic Stress
- (2010) Amar J. Majmundar et al. MOLECULAR CELL
- IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas
- (2010) C. Houillier et al. NEUROLOGY
- Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
- (2010) A. Le et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- LKB1 and AMP-activated protein kinase control of mTOR signalling and growth
- (2009) R. J. Shaw Acta Physiologica
- Diabetes Mellitus in Long-term Survivors of Childhood Cancer
- (2009) Lillian R. Meacham et al. ARCHIVES OF INTERNAL MEDICINE
- Quantitative Metabolome Profiling of Colon and Stomach Cancer Microenvironment by Capillary Electrophoresis Time-of-Flight Mass Spectrometry
- (2009) A. Hirayama et al. CANCER RESEARCH
- l-Type amino acid transporter 1 inhibitors inhibit tumor cell growth
- (2009) Koji Oda et al. CANCER SCIENCE
- Enzymology of Purine and Pyrimidine Antimetabolites Used in the Treatment of Cancer
- (2009) William B. Parker CHEMICAL REVIEWS
- Evaluation of 13C isotopic tracers for metabolic flux analysis in mammalian cells
- (2009) Christian M. Metallo et al. JOURNAL OF BIOTECHNOLOGY
- Clinical studies for improving radiotherapy with 2-deoxy-D-glucose: Present status and future prospects
- (2009) BS Dwarakanath et al. Journal of Cancer Research and Therapeutics
- Characterization of Urinary Biomarkers of Hepatocellular Carcinoma Using Magnetic Resonance Spectroscopy in a Nigerian Population
- (2009) Mohamed I. F. Shariff et al. JOURNAL OF PROTEOME RESEARCH
- Altered regulation of metabolic pathways in human lung cancer discerned by 13C stable isotope-resolved metabolomics (SIRM)
- (2009) Teresa WM Fan et al. Molecular Cancer
- Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
- (2009) Lenny Dang et al. NATURE
- Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression
- (2009) Arun Sreekumar et al. NATURE
- Tumours with PI3K activation are resistant to dietary restriction
- (2009) Nada Y. Kalaany et al. NATURE
- IDH1andIDH2Mutations in Gliomas
- (2009) Hai Yan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Cancer Cell Metabolism: Warburg and Beyond
- (2008) Peggy P. Hsu et al. CELL
- Recommendations on the Use of 18F-FDG PET in Oncology
- (2008) J. W. Fletcher et al. JOURNAL OF NUCLEAR MEDICINE
- The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
- (2008) Heather R. Christofk et al. NATURE
- High-throughput, nontargeted metabolite fingerprinting using nominal mass flow injection electrospray mass spectrometry
- (2008) Manfred Beckmann et al. Nature Protocols
- Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
- (2008) D. R. Wise et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The metabolites citrate, myo-inositol, and spermine are potential age-independent markers of prostate cancer in human expressed prostatic secretions
- (2008) Natalie J. Serkova et al. PROSTATE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now