Metabolomics of Human Cerebrospinal Fluid Identifies Signatures of Malignant Glioma

A positive/negative ion–switching, targeted mass spectrometry–based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue

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IDH1 R132H decreases proliferation of glioma cell lines in vitro and in vivo

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Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

(2011) Eric A Collisson et al.   NATURE MEDICINE

The Cerebrospinal Fluid Provides a Proliferative Niche for Neural Progenitor Cells

(2011) Maria K. Lehtinen et al.   NEURON

Disease-Related Changes in the Cerebrospinal Fluid Metabolome in Amyotrophic Lateral Sclerosis Detected by GC/TOFMS

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Metabolomic Profiling from Formalin-Fixed, Paraffin-Embedded Tumor Tissue Using Targeted LC/MS/MS: Application in Sarcoma

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Immunity, Inflammation, and Cancer

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Prognostic and Predictive Gene Signature for Adjuvant Chemotherapy in Resected Non–Small-Cell Lung Cancer

(2010) Chang-Qi Zhu et al.   JOURNAL OF CLINICAL ONCOLOGY

LC-MS based serum metabonomic analysis for renal cell carcinoma diagnosis, staging, and biomarker discovery

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Quantitative Proteomics and Metabolomics Analysis of Normal Human Cerebrospinal Fluid Samples*

(2010) Marcel P. Stoop et al.   MOLECULAR & CELLULAR PROTEOMICS

Metabolic Modulation of Glioblastoma with Dichloroacetate

(2010) E. D. Michelakis et al.   Science Translational Medicine

Variability Analysis of Human Plasma and Cerebral Spinal Fluid Reveals Statistical Significance of Changes in Mass Spectrometry-Based Metabolomics Data

(2009) Bridgit Crews et al.   ANALYTICAL CHEMISTRY

Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction

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The Effect of Preanalytical Factors on Stability of the Proteome and Selected Metabolites in Cerebrospinal Fluid (CSF)

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Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

(2009) Lenny Dang et al.   NATURE

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

(2009) Arun Sreekumar et al.   NATURE

Cancer's insatiable appetite

(2009) Jason W Locasale et al.   NATURE BIOTECHNOLOGY

Untreated Glioblastoma Multiforme: IncreasedMyo-inositol and Glutamine Levels in the Contralateral Cerebral Hemisphere at Proton MR Spectroscopy

(2009) Kai Kallenberg et al.   RADIOLOGY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism

Analytical strategies for LC–MS-based targeted metabolomics

(2008) Wenyun Lu et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

The human cerebrospinal fluid metabolome

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Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease

(2008) Luigina Romani et al.   NATURE

What is principal component analysis?

(2008) Markus Ringnér   NATURE BIOTECHNOLOGY

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE