VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma

VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma

(2017) Xiaosai Yao et al.   Cancer Discovery

Renal cell carcinoma

(2017) James J. Hsieh et al.   Nature Reviews Disease Primers

Expression and prognostic significance of zinc fingers and homeoboxes family members in renal cell carcinoma

(2017) Ryuk-Jun Kwon et al.   PLoS One

Characterization of VHL missense mutations in sporadic clear cell renal cell carcinoma: hotspots, affected binding domains, functional impact on pVHL and therapeutic relevance

(2016) Caroline Razafinjatovo et al.   BMC CANCER

Epigenetic Perturbations by Arg882-Mutated DNMT3A Potentiate Aberrant Stem Cell Gene-Expression Program and Acute Leukemia Development

(2016) Rui Lu et al.   CANCER CELL

Germline Analysis from Tumor–Germline Sequencing Dyads to Identify Clinically Actionable Secondary Findings

(2016) Bryce A. Seifert et al.   CLINICAL CANCER RESEARCH

Targeting renal cell carcinoma with a HIF-2 antagonist

(2016) Wenfang Chen et al.   NATURE

On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models

(2016) Hyejin Cho et al.   NATURE

EglN2 associates with the NRF1‐PGC1α complex and controls mitochondrial function in breast cancer

(2015) Jing Zhang et al.   EMBO JOURNAL

HIF2 -Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma

(2015) B. Qiu et al.   Cancer Discovery

Combined Targeted DNA Sequencing in Non-Small Cell Lung Cancer (NSCLC) Using UNCseq and NGScopy, and RNA Sequencing Using UNCqeR for the Detection of Genetic Aberrations in NSCLC

(2015) Xiaobei Zhao et al.   PLoS One

ZHX2 enhances the cytotoxicity of chemotherapeutic drugs in liver tumor cells by repressing MDR1 via interfering with NF-YA

(2015) Hongxin Ma et al.   Oncotarget

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

(2014) Xi Chen et al.   NATURE

Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis

(2014) X-D Liu et al.   ONCOGENE

SQSTM1 Is a Pathogenic Target of 5q Copy Number Gains in Kidney Cancer

(2013) Lianjie Li et al.   CANCER CELL

Integrated molecular analysis of clear-cell renal cell carcinoma

(2013) Yusuke Sato et al.   NATURE GENETICS

Canonical and non-canonical NF-κB signaling promotes breast cancer tumor-initiating cells

(2013) M F Kendellen et al.   ONCOGENE

Oncogenic PI3K Mutations Lead to NF- B-Dependent Cytokine Expression following Growth Factor Deprivation

(2012) J. E. Hutti et al.   CANCER RESEARCH

Zinc Fingers and Homeoboxes 2 Inhibits Hepatocellular Carcinoma Cell Proliferation and Represses Expression of Cyclins A and E

(2012) Xuetian Yue et al.   GASTROENTEROLOGY

Celebrating 25 years of NF-κB research

(2012) Sankar Ghosh et al.   IMMUNOLOGICAL REVIEWS

TRIM32 Protein Modulates Type I Interferon Induction and Cellular Antiviral Response by Targeting MITA/STING Protein for K63-linked Ubiquitination

(2012) Jing Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Treatment selection in metastatic renal cell carcinoma: expert consensus

(2012) Bernard Escudier et al.   Nature Reviews Clinical Oncology

Transcriptional deregulation of homeobox gene ZHX2 in Hodgkin lymphoma

(2011) Stefan Nagel et al.   LEUKEMIA RESEARCH

Targeting GLUT1 and the Warburg Effect in Renal Cell Carcinoma by Chemical Synthetic Lethality

(2011) D. A. Chan et al.   Science Translational Medicine

Fast and SNP-tolerant detection of complex variants and splicing in short reads

(2010) T. D. Wu et al.   BIOINFORMATICS

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Oncogenic Activation of NF- B

(2010) L. M. Staudt   Cold Spring Harbor Perspectives in Biology

TagDust--a program to eliminate artifacts from next generation sequencing data

(2009) T. Lassmann et al.   BIOINFORMATICS

Control of Cyclin D1 and Breast Tumorigenesis by the EglN2 Prolyl Hydroxylase

(2009) Qing Zhang et al.   CANCER CELL

ZHX2 is a repressor of α-fetoprotein expression in human hepatoma cell lines

(2009) H. Shen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Scoring of p16INK4a immunohistochemistry based on independent nuclear staining alone can sufficiently distinguish between endocervical and endometrial adenocarcinomas in a tissue microarray study

(2009) Chih-Ping Han et al.   MODERN PATHOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

HIF-α Effects on c-Myc Distinguish Two Subtypes of Sporadic VHL-Deficient Clear Cell Renal Carcinoma

(2008) John D. Gordan et al.   CANCER CELL

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY