High stearoyl-CoA desaturase 1 expression is associated with shorter survival in breast cancer patients

PIK3CA/PTEN Mutations and Akt Activation As Markers of Sensitivity to Allosteric mTOR Inhibitors

(2012) F. Meric-Bernstam et al.   CLINICAL CANCER RESEARCH

mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

(2011) Timothy R. Peterson et al.   CELL

Cancer Cell Dependence on Unsaturated Fatty Acids Implicates Stearoyl-CoA Desaturase as a Target for Cancer Therapy

(2011) U. V. Roongta et al.   MOLECULAR CANCER RESEARCH

Stearoyl-CoA desaturase-1: a novel key player in the mechanisms of cell proliferation, programmed cell death and transformation to cancer

(2010) R. A. Igal   CARCINOGENESIS

Predictors of Tumor Progression During Neoadjuvant Chemotherapy in Breast Cancer

(2010) Abigail S. Caudle et al.   JOURNAL OF CLINICAL ONCOLOGY

Key role of the ERK1/2 MAPK pathway in the transcriptional regulation of the Stearoyl-CoA Desaturase (SCD1) gene expression in response to leptin

(2010) Daniel Mauvoisin et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Rapamycin Regulates Stearoyl CoA Desaturase 1 Expression in Breast Cancer

(2010) D. Luyimbazi et al.   MOLECULAR CANCER THERAPEUTICS

Abrogation of De novo Lipogenesis by Stearoyl-CoA Desaturase 1 Inhibition Interferes with Oncogenic Signaling and Blocks Prostate Cancer Progression in Mice

(2010) V. Fritz et al.   MOLECULAR CANCER THERAPEUTICS

Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1

(2010) Katrin Düvel et al.   MOLECULAR CELL

Inhibition of StearoylCoA Desaturase Activity Blocks Cell Cycle Progression and Induces Programmed Cell Death in Lung Cancer Cells

(2010) Daniel Hess et al.   PLoS One

Evidence that Inositol Polyphosphate 4-Phosphatase Type II Is a Tumor Suppressor that Inhibits PI3K Signaling

(2009) Christina Gewinner et al.   CANCER CELL

Dysregulation of sterol regulatory element binding protein–1c in livers of morbidly obese women is associated with altered suppressor of cytokine signaling–3 and signal transducer and activator of transcription–1 signaling

(2009) Marshall B. Elam et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Inhibition of StearoylCoA Desaturase-1 Inactivates Acetyl-CoA Carboxylase and Impairs Proliferation in Cancer Cells: Role of AMPK

(2009) Natalia Scaglia et al.   PLoS One

Association between Serum trans-Monounsaturated Fatty Acids and Breast Cancer Risk in the E3N-EPIC Study

(2008) V. Chajes et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Mechanisms of antidiabetogenic and body weight-lowering effects of estrogen in high-fat diet-fed mice

(2008) Galyna Bryzgalova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Development of a high-throughput screening assay for stearoyl-CoA desaturase using rat liver microsomes, deuterium labeled stearoyl-CoA and mass spectrometry

(2008) Patricia Soulard et al.   ANALYTICA CHIMICA ACTA

Development of a novel LC/MS method to quantitate cellular stearoyl-CoA desaturase activity

(2008) Roslyn Dillon et al.   ANALYTICA CHIMICA ACTA

Discovery of piperidine-aryl urea-based stearoyl-CoA desaturase 1 inhibitors

(2008) Zhili Xin et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS