标题
Hedgehog and Gpr161: Regulating cAMP Signaling in the Primary Cilium
作者
关键词
-
出版物
Cells
Volume 9, Issue 1, Pages 118
出版商
MDPI AG
发表日期
2020-01-04
DOI
10.3390/cells9010118
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Ciliotherapy: Remote Control of Primary Cilia Movement and Function by Magnetic Nanoparticles
- (2019) Rajasekharreddy Pala et al. ACS Nano
- Biochemical mechanisms of vertebrate hedgehog signaling
- (2019) Jennifer H. Kong et al. DEVELOPMENT
- The Nuclear Arsenal of Cilia
- (2019) Colin A. Johnson et al. DEVELOPMENTAL CELL
- Establishing and regulating the composition of cilia for signal transduction
- (2019) Maxence V. Nachury et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Direct visualization of cAMP signaling in primary cilia reveals up-regulation of ciliary GPCR activity following Hedgehog activation
- (2019) Jason Y. Jiang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system
- (2019) Laura Rinaldi et al. Nature Communications
- Sensory primary cilium is a responsive cAMP microdomain in renal epithelia
- (2019) Rinzhin T. Sherpa et al. Scientific Reports
- Non-canonical Hedgehog Signaling Pathway in Cancer: Activation of GLI Transcription Factors Beyond Smoothened
- (2019) Silvia Pietrobono et al. Frontiers in Genetics
- GPR17 is an essential regulator for the temporal adaptation of sonic hedgehog signalling in neural tube development
- (2019) Atsuki Yatsuzuka et al. DEVELOPMENT
- Therapeutic targeting of 3′,5′-cyclic nucleotide phosphodiesterases: inhibition and beyond
- (2019) George S. Baillie et al. NATURE REVIEWS DRUG DISCOVERY
- Overcoming the resistance mechanisms of Smoothened inhibitors
- (2018) Xiaochun Dong et al. DRUG DISCOVERY TODAY
- G protein–coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog
- (2018) Ganesh V. Pusapati et al. Science Signaling
- Ras and Rap1: A tale of two GTPases
- (2018) Seema Shah et al. SEMINARS IN CANCER BIOLOGY
- cAMP: From Long-Range Second Messenger to Nanodomain Signalling
- (2018) Nshunge Musheshe et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Counterregulation of cAMP-directed kinase activities controls ciliogenesis
- (2018) Monia Porpora et al. Nature Communications
- G protein–coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog
- (2018) Ganesh V. Pusapati et al. Science Signaling
- Metabolism and mitochondria in polycystic kidney disease research and therapy
- (2018) Valeria Padovano et al. Nature Reviews Nephrology
- Personalized Nanotherapy by Specifically Targeting Cell Organelles To Improve Vascular Hypertension
- (2018) Rajasekharreddy Pala et al. NANO LETTERS
- Targeting the Oncoprotein Smoothened by Small Molecules: Focus on Novel Acylguanidine Derivatives as Potent Smoothened Inhibitors
- (2018) Silvia Pietrobono et al. Cells
- Genes and molecular pathways underpinning ciliopathies
- (2017) Jeremy F. Reiter et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Adenylyl cyclase signalling complexes – Pharmacological challenges and opportunities
- (2017) Michelle L. Halls et al. PHARMACOLOGY & THERAPEUTICS
- G-Protein-Coupled Receptor Signaling in Cilia
- (2017) Kirk Mykytyn et al. Cold Spring Harbor Perspectives in Biology
- GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling
- (2016) Alex R.B. Thomsen et al. CELL
- The primary cilium as a cellular receiver: organizing ciliary GPCR signaling
- (2016) Keren I Hilgendorf et al. CURRENT OPINION IN CELL BIOLOGY
- Structure of smAKAP and its regulation by PKA-mediated phosphorylation
- (2016) Pepijn P. Burgers et al. FEBS Journal
- Protein kinase A catalytic subunit isoform PRKACA; History, function and physiology
- (2016) Rigney E. Turnham et al. GENE
- Protein Kinase A-independent Ras Protein Activation Cooperates with Rap1 Protein to Mediate Activation of the Extracellular Signal-regulated Kinases (ERK) by cAMP
- (2016) Yanping Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphorylation of Rap1 by cAMP-dependent Protein Kinase (PKA) Creates a Binding Site for KSR to Sustain ERK Activation by cAMP
- (2016) Maho Takahashi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Smoothened determines β-arrestin–mediated removal of the G protein–coupled receptor Gpr161 from the primary cilium
- (2016) Kasturi Pal et al. JOURNAL OF CELL BIOLOGY
- Gpr161 anchoring of PKA consolidates GPCR and cAMP signaling
- (2016) Verena A. Bachmann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cilia have high cAMP levels that are inhibited by Sonic Hedgehog-regulated calcium dynamics
- (2016) Bryn S. Moore et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Popeye domain containing protein family – A novel class of cAMP effectors with important functions in multiple tissues
- (2016) Roland F.R. Schindler et al. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
- Bimodal antagonism of PKA signalling by ARHGAP36
- (2016) Rebecca L. Eccles et al. Nature Communications
- A novel biosensor to study cAMP dynamics in cilia and flagella
- (2016) Shatanik Mukherjee et al. eLife
- PKA-Type I Selective Constrained Peptide Disruptors of AKAP Complexes
- (2015) Yuxiao Wang et al. ACS Chemical Biology
- Proteomics of Primary Cilia by Proximity Labeling
- (2015) David U. Mick et al. DEVELOPMENTAL CELL
- Ins and outs of GPCR signaling in primary cilia
- (2015) K. B. Schou et al. EMBO REPORTS
- The Orphan G Protein-coupled Receptor Gpr175 (Tpra40) Enhances Hedgehog Signaling by Modulating cAMP Levels
- (2015) Jaskirat Singh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Signalling scaffolds and local organization of cellular behaviour
- (2015) Lorene K. Langeberg et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A dynamic interface between ubiquitylation and cAMP signaling
- (2015) Laura Rinaldi et al. Frontiers in Pharmacology
- Targeting protein–protein interactions in complexes organized by A kinase anchoring proteins
- (2015) Ana I. Calejo et al. Frontiers in Pharmacology
- Specialized Cilia in Mammalian Sensory Systems
- (2015) Nathalie Falk et al. Cells
- Decoding spatial and temporal features of neuronal cAMP/PKA signaling with FRET biosensors
- (2014) Liliana R. V. Castro et al. Biotechnology Journal
- Novel insights into G protein and G protein-coupled receptor signaling in cancer
- (2014) Morgan O’Hayre et al. CURRENT OPINION IN CELL BIOLOGY
- Advances in targeting cyclic nucleotide phosphodiesterases
- (2014) Donald H. Maurice et al. NATURE REVIEWS DRUG DISCOVERY
- Targeting of Smoothened for therapeutic gain
- (2014) Martial Ruat et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- PKA: Lessons learned after twenty years
- (2013) Susan S. Taylor et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- The Ciliary G-Protein-Coupled Receptor Gpr161 Negatively Regulates the Sonic Hedgehog Pathway via cAMP Signaling
- (2013) Saikat Mukhopadhyay et al. CELL
- Kinetics and mechanism of G protein-coupled receptor activation
- (2013) Martin J Lohse et al. CURRENT OPINION IN CELL BIOLOGY
- Biophysical Techniques for Detection of cAMP and cGMP in Living Cells
- (2013) Julia Sprenger et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The mechanisms of Hedgehog signalling and its roles in development and disease
- (2013) James Briscoe et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- GPR88 Reveals a Discrete Function of Primary Cilia as Selective Insulators of GPCR Cross-Talk
- (2013) Aaron Marley et al. PLoS One
- G-Protein Coupled Receptor Resensitization - Appreciating the Balancing Act of Receptor Function
- (2013) Maradumane L. Mohan et al. Current Molecular Pharmacology
- Creating Order from Chaos: Cellular Regulation by Kinase Anchoring
- (2012) John D. Scott et al. Annual Review of Pharmacology and Toxicology
- Zebrafish Cxcr4a determines the proliferative response to Hedgehog signalling
- (2012) T. Stuckemann et al. DEVELOPMENT
- NOS-2 signaling and cancer therapy
- (2012) Ka Bian et al. IUBMB LIFE
- A Small Novel A-Kinase Anchoring Protein (AKAP) That Localizes Specifically Protein Kinase A-Regulatory Subunit I (PKA-RI) to the Plasma Membrane
- (2012) Pepijn P. Burgers et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Popeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in mice
- (2012) Alexander Froese et al. JOURNAL OF CLINICAL INVESTIGATION
- Assembly of allosteric macromolecular switches: lessons from PKA
- (2012) Susan S. Taylor et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting
- (2012) M. C. Humbert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Hedgehog Signal Transduction Network
- (2012) D. J. Robbins et al. Science Signaling
- Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube
- (2011) M. Tuson et al. DEVELOPMENT
- Reorganized PKA-AKAP associations in the failing human heart
- (2011) Thin-Thin Aye et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Mechanisms and functions of Hedgehog signalling across the metazoa
- (2011) Philip W. Ingham et al. NATURE REVIEWS GENETICS
- Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases
- (2011) Y.-H. Choi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Scaffold Proteins: Hubs for Controlling the Flow of Cellular Information
- (2011) M. C. Good et al. SCIENCE
- PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades
- (2011) Eduard Stefan et al. Nature Communications
- Epac: Defining a New Mechanism for cAMP Action
- (2010) Martijn Gloerich et al. Annual Review of Pharmacology and Toxicology
- Networking with AKAPs: Context-dependent Regulation of Anchored Enzymes
- (2010) E. J. Welch et al. MOLECULAR INTERVENTIONS
- Teaching old receptors new tricks: biasing seven-transmembrane receptors
- (2010) Sudarshan Rajagopal et al. NATURE REVIEWS DRUG DISCOVERY
- The primary cilium: a signalling centre during vertebrate development
- (2010) Sarah C. Goetz et al. NATURE REVIEWS GENETICS
- Signal integration through blending, bolstering and bifurcating of intracellular information
- (2010) Catherine T Pawson et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Compartmentalized signalling: spatial regulation of cAMP by the action of compartmentalized phosphodiesterases
- (2009) George S. Baillie FEBS Journal
- Sonic-hedgehog-mediated proliferation requires the localization of PKA to the cilium base
- (2009) M. Barzi et al. JOURNAL OF CELL SCIENCE
- Adenylyl Cyclase-A-kinase Anchoring Protein Complexes: The Next Dimension in cAMP Signaling
- (2009) C. W. Dessauer MOLECULAR PHARMACOLOGY
- Phosphodiesterase 1C is dispensable for rapid response termination of olfactory sensory neurons
- (2009) Katherine D Cygnar et al. NATURE NEUROSCIENCE
- Cell Signaling in Space and Time: Where Proteins Come Together and When They're Apart
- (2009) J. D. Scott et al. SCIENCE
- Underpinning compartmentalised cAMP signalling through targeted cAMP breakdown
- (2009) Miles D. Houslay TRENDS IN BIOCHEMICAL SCIENCES
- Persistent cAMP-Signals Triggered by Internalized G-Protein–Coupled Receptors
- (2009) Davide Calebiro et al. PLOS BIOLOGY
- Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network
- (2008) E. Dessaud et al. DEVELOPMENT
- Location, location, location…site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling
- (2008) Andrew B. Tobin et al. TRENDS IN PHARMACOLOGICAL SCIENCES
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started