Biophysical Techniques for Detection of cAMP and cGMP in Living Cells

Creating Order from Chaos: Cellular Regulation by Kinase Anchoring

(2012) John D. Scott et al.   Annual Review of Pharmacology and Toxicology

cGMP–cAMP interplay in cardiac myocytes: a local affair with far-reaching consequences for heart function

(2012) Alessandra Stangherlin et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Phosphoinositide 3-Kinase γ Protects Against Catecholamine-Induced Ventricular Arrhythmia Through Protein Kinase A–Mediated Regulation of Distinct Phosphodiesterases

(2012) Alessandra Ghigo et al.   CIRCULATION

Cyclic AMP underpins suppression by regulatory T cells

(2012) Josef Bodor et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The cyclic nucleotide cGMP is involved in plant hormone signalling and alters phosphorylation of Arabidopsis thaliana root proteins

(2012) Jean Charles Isner et al.   JOURNAL OF EXPERIMENTAL BOTANY

Regulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP

(2012) Vedangi Sample et al.   Nature Chemical Biology

A-kinase anchoring proteins: scaffolding proteins in the heart

(2011) Dario Diviani et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Modulation of T cell immune functions by the prostaglandin E2 - cAMP pathway in chronic inflammatory states

(2011) Kristoffer Watten Brudvik et al.   BRITISH JOURNAL OF PHARMACOLOGY

A-kinase anchoring proteins as potential drug targets

(2011) Jessica Tröger et al.   BRITISH JOURNAL OF PHARMACOLOGY

cGMP Signals Modulate cAMP Levels in a Compartment-Specific Manner to Regulate Catecholamine-Dependent Signaling in Cardiac Myocytes

(2011) Alessandra Stangherlin et al.   CIRCULATION RESEARCH

Plasma Membrane Calcium Pump (PMCA4)-Neuronal Nitric-oxide Synthase Complex Regulates Cardiac Contractility through Modulation of a Compartmentalized Cyclic Nucleotide Microdomain

(2011) Tamer M. A. Mohamed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Ion-insensitive cAMP Biosensor for Long Term Quantitative Ratiometric Fluorescence Resonance Energy Transfer (FRET) Measurements under Variable Physiological Conditions

(2011) Petrus S. Salonikidis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disruption of the cyclic AMP phosphodiesterase-4 (PDE4)–HSP20 complex attenuates the β-agonist induced hypertrophic response in cardiac myocytes

(2011) Y.Y. Sin et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells

(2011) Sebastian Börner et al.   Nature Protocols

CREB and the CRTC co-activators: sensors for hormonal and metabolic signals

(2011) Judith Y. Altarejos et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cyclic AMP Control Measured in Two Compartments in HEK293 Cells: Phosphodiesterase KM Is More Important than Phosphodiesterase Localization

(2011) Karina Matthiesen et al.   PLoS One

Epac: Defining a New Mechanism for cAMP Action

(2010) Martijn Gloerich et al.   Annual Review of Pharmacology and Toxicology

FRET-based direct detection of dynamic protein kinase A activity on the sarcoplasmic reticulum in cardiomyocytes

(2010) Shubai Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5

(2010) Ronald Jäger et al.   BRITISH JOURNAL OF PHARMACOLOGY

Ca 2+ Cycling and New Therapeutic Approaches for Heart Failure

(2010) Anne-Marie Lompré et al.   CIRCULATION

Feedback Control Through cGMP-Dependent Protein Kinase Contributes to Differential Regulation and Compartmentation of cGMP in Rat Cardiac Myocytes

(2010) Liliana R.V. Castro et al.   CIRCULATION RESEARCH

Visualization of PKA activity in plasma membrane microdomains

(2010) Charlene Depry et al.   Molecular BioSystems

Measurement of cellular cGMP in plant cells and tissues using the endogenous fluorescent reporter FlincG

(2010) Jean-Charles Isner et al.   PLANT JOURNAL

 2-Adrenergic Receptor Redistribution in Heart Failure Changes cAMP Compartmentation

(2010) V. O. Nikolaev et al.   SCIENCE

cAMP signal transduction in the heart: understanding spatial control for the development of novel therapeutic strategies

(2009) Manuela Zaccolo   BRITISH JOURNAL OF PHARMACOLOGY

Decreased Expression and Activity of cAMP Phosphodiesterases in Cardiac Hypertrophy and Its Impact on β-Adrenergic cAMP Signals

(2009) Aniella Abi-Gerges et al.   CIRCULATION RESEARCH

Cyclic GMP from the surrounding somatic cells regulates cyclic AMP and meiosis in the mouse oocyte

(2009) R. P. Norris et al.   DEVELOPMENT

Distinct pools of cAMP centre on different isoforms of adenylyl cyclase in pituitary-derived GH3B6 cells

(2009) S. Wachten et al.   JOURNAL OF CELL SCIENCE

Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics

(2009) Emily J. Tsai et al.   PHARMACOLOGY & THERAPEUTICS

Hyperpolarization-Activated Cation Channels: From Genes to Function

(2009) Martin Biel et al.   PHYSIOLOGICAL REVIEWS

Simultaneous Live Cell Imaging Using Dual FRET Sensors with a Single Excitation Light

(2009) Yusuke Niino et al.   PLoS One

Persistent cAMP-Signals Triggered by Internalized G-Protein–Coupled Receptors

(2009) Davide Calebiro et al.   PLOS BIOLOGY

Cytoplasmic cAMP concentrations in intact cardiac myocytes

(2008) Radu V. Iancu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The GAF Domain of the cGMP-Binding, cGMP-Specific Phosphodiesterase (PDE5) Is a Sensor and a Sink for cGMP†

(2008) Kabir Hassan Biswas et al.   BIOCHEMISTRY

Glucose-Induced Cyclic AMP Oscillations Regulate Pulsatile Insulin Secretion

(2008) Oleg Dyachok et al.   Cell Metabolism

Real-time monitoring of phosphodiesterase inhibition in intact cells

(2008) Sabine Herget et al.   CELLULAR SIGNALLING

Protein Kinase A Type I and Type II Define Distinct Intracellular Signaling Compartments

(2008) Giulietta Di Benedetto et al.   CIRCULATION RESEARCH

Oscillatory control of insulin secretion

(2008) A TENGHOLM et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Pharmacological Characterization of Membrane-Expressed Human Trace Amine-Associated Receptor 1 (TAAR1) by a Bioluminescence Resonance Energy Transfer cAMP Biosensor

(2008) L. S. Barak et al.   MOLECULAR PHARMACOLOGY

Signaling through cAMP and cAMP-dependent protein kinase: Diverse strategies for drug design

(2007) Susan S. Taylor et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS