Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits

Neurodegenerative lysosomal disorders: A continuum from development to late age

(2014) Ralph A. Nixon et al.   Autophagy

Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations

(2010) Ju-Hyun Lee et al.   CELL

Review on the APP/PS1KI mouse model: intraneuronal Aβ accumulation triggers axonopathy, neuron loss and working memory impairment

(2010) T. A. Bayer et al.   GENES BRAIN AND BEHAVIOR

Olfactory Dysfunction Correlates with Amyloid-  Burden in an Alzheimer's Disease Mouse Model

(2010) D. W. Wesson et al.   JOURNAL OF NEUROSCIENCE

Induction of Autophagy by Cystatin C: A Mechanism That Protects Murine Primary Cortical Neurons and Neuronal Cell Lines

(2010) Belen Tizon et al.   PLoS One

Amyloid β and impairment in multiple memory systems in older transgenic APP TgCRND8 mice

(2009) A. Hanna et al.   GENES BRAIN AND BEHAVIOR

Interaction between Oligomers of Stefin B and Amyloid-βin Vitroand in Cells

(2009) Katja Škerget et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysosomes as “Suicide Bags” in Cell Death: Myth or Reality?

(2009) Boris Turk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cystatin B Deficiency Sensitizes Neurons to Oxidative Stress in Progressive Myoclonus Epilepsy, EPM1

(2009) M. K. Lehtinen et al.   JOURNAL OF NEUROSCIENCE

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Alzheimer's-related endosome dysfunction in Down syndrome is A -independent but requires APP and is reversed by BACE-1 inhibition

(2009) Y. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chaperone-mediated autophagy: selectivity pays off

(2009) Ana Maria Cuervo   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Transient intraneuronal Aβ rather than extracellular plaque pathology correlates with neuron loss in the frontal cortex of APP/PS1KI mice

(2008) Ditte Zerlang Christensen et al.   ACTA NEUROPATHOLOGICA

Size and morphology of toxic oligomers of amyloidogenic proteins: a case study of human stefin B

(2008) Slavko Čeru et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Autophagy and multivesicular bodies: two closely related partners

(2008) C M Fader et al.   CELL DEATH AND DIFFERENTIATION

Cystatins: Biochemical and structural properties, and medical relevance

(2008) ">Vito Turk   Frontiers in Bioscience-Landmark

Activation of the Amyloid Cascade in Apolipoprotein E4 Transgenic Mice Induces Lysosomal Activation and Neurodegeneration Resulting in Marked Cognitive Deficits

(2008) H. Belinson et al.   JOURNAL OF NEUROSCIENCE

Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease

(2008) B. Boland et al.   JOURNAL OF NEUROSCIENCE

Small molecule enhancers of autophagy for neurodegenerative diseases

(2008) Sovan Sarkar et al.   Molecular BioSystems

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model

(2008) Ryoichi Kimura et al.   NEUROBIOLOGY OF DISEASE

Cystatin C-Cathepsin B Axis Regulates Amyloid Beta Levels and Associated Neuronal Deficits in an Animal Model of Alzheimer's Disease

(2008) Binggui Sun et al.   NEURON

Cystatin B and its EPM1 mutants are polymeric and aggregate prone in vivo

(2007) Elena Cipollini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Molecular background of EPM1—Unverricht–Lundborg disease

(2007) Tarja Joensuu et al.   EPILEPSIA

The autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapy

(2007) John et al.   Frontiers in Bioscience-Landmark