A Hierarchical Whole-body Modeling Approach Elucidates the Link betweenin VitroInsulin Signaling andin VivoGlucose Homeostasis

Glucose Levels at the Site of Subcutaneous Insulin Administration and Their Relationship to Plasma Levels

(2010) S. Lindpointner et al.   DIABETES CARE

Mass and Information Feedbacks through Receptor Endocytosis Govern Insulin Signaling as Revealed Using a Parameter-free Modeling Framework

(2010) Cecilia Brännmark et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Grand challenges in systems physiology

(2010) Hiroaki Kitano   Frontiers in Physiology

The crosstalk between EGF, IGF, and Insulin cell signaling pathways - computational and experimental analysis

(2009) Rafal Zielinski et al.   BMC Systems Biology

Systems biology: model based evaluation and comparison of potential explanations for given biological data

(2009) Gunnar Cedersund et al.   FEBS Journal

Rates of Glucose Uptake in Adipose Tissue and Musclein Vivoafter a Mixed Meal in Women with Morbid Obesity

(2009) Panayota Mitrou et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Density functional computational studies on (E)-2-[(2-Hydroxy-5-nitrophenyl)-iminiomethyl]-4-nitrophenolate

(2009) Hasan Tanak et al.   JOURNAL OF MOLECULAR MODELING

Men develop more intraabdominal obesity and signs of the metabolic syndrome after hyperalimentation than women

(2009) Styrbjörn Erlingsson et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Modeling of glucose regulation and insulin-signaling pathways

(2009) Yin Hoon Chew et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Systems-level interactions between insulin–EGF networks amplify mitogenic signaling

(2009) Nikolay Borisov et al.   Molecular Systems Biology

Harmonic oscillator model of the insulin and IGF1 receptors’ allosteric binding and activation

(2009) Vladislav V Kiselyov et al.   Molecular Systems Biology

A Dynamic Analysis of IRS-PKR Signaling in Liver Cells: A Discrete Modeling Approach

(2009) Ming Wu et al.   PLoS One

All systems go

(2008)   NATURE REVIEWS DRUG DISCOVERY

Model-Based Hypothesis Testing of Key Mechanisms in Initial Phase of Insulin Signaling

(2008) Gunnar Cedersund et al.   PLoS Computational Biology