标题
Autophagy in adipose tissue and the beta cell: implications for obesity and diabetes
作者
关键词
Adipocyte, Adipose tissue, Apoptosis, Autophagy, Beta cell, Diabetes, ER stress, Inflammation, Insulin resistance, Macrophage, Obesity
出版物
DIABETOLOGIA
Volume 57, Issue 8, Pages 1505-1516
出版商
Springer Nature
发表日期
2014-05-04
DOI
10.1007/s00125-014-3255-3
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- LAMP-2: A control step for phagosome and autophagosome maturation
- (2014) Paul Saftig et al. Autophagy
- Autophagy is involved in adipogenic differentiation by repressesing proteasome-dependent PPARγ2 degradation
- (2013) Chongben Zhang et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Autophagy in obesity and atherosclerosis: Interrelationships between cholesterol homeostasis, lipoprotein metabolism and autophagy in macrophages and other systems
- (2013) Mireille Ouimet BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- The Relationship between Metabolism and the Autophagy Machinery during the Innate Immune Response
- (2013) Jennifer Martinez et al. Cell Metabolism
- Metabolic endotoxaemia
- (2013) Milan K. Piya et al. CURRENT OPINION IN LIPIDOLOGY
- Evidence for Rapamycin Toxicity in Pancreatic β-Cells and a Review of the Underlying Molecular Mechanisms
- (2013) Adam D. Barlow et al. DIABETES
- Reduced Adipose Tissue Macrophage Content Is Associated With Improved Insulin Sensitivity in Thiazolidinedione-Treated Diabetic Humans
- (2013) S. Koppaka et al. DIABETES
- The Type 2 Diabetes-Associated Gene Ide Is Required for Insulin Secretion and Suppression of -Synuclein Levels in -Cells
- (2013) P. Steneberg et al. DIABETES
- Lysosomal acid lipase and lipophagy are constitutive negative regulators of glucose-stimulated insulin secretion from pancreatic beta cells
- (2013) Gemma L. Pearson et al. DIABETOLOGIA
- Defective regulation of adipose tissue autophagy in obesity
- (2013) C E Nuñez et al. INTERNATIONAL JOURNAL OF OBESITY
- Insulin Signaling in Type 2 Diabetes
- (2013) Cecilia Brännmark et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cathepsin B Contributes to Autophagy-related 7 (Atg7)-induced Nod-like Receptor 3 (NLRP3)-dependent Proinflammatory Response and Aggravates Lipotoxicity in Rat Insulinoma Cell Line
- (2013) Shali Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of a candidate therapeutic autophagy-inducing peptide
- (2013) Sanae Shoji-Kawata et al. NATURE
- Metabolism of inflammation limited by AMPK and pseudo-starvation
- (2013) Luke A. J. O'Neill et al. NATURE
- Autophagy in Human Health and Disease
- (2013) Augustine M.K. Choi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Autophagy as a crosstalk mediator of metabolic organs in regulation of energy metabolism
- (2013) Kook Hwan Kim et al. REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
- Role of Rapamycin-Induced Autophagy in Pancreatic Islets
- (2012) M. Tanemura et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Autophagy plays a protective role in endoplasmic reticulum stress-mediated pancreatic β cell death
- (2012) Alberto Bartolome et al. Autophagy
- The end of autophagic cell death?
- (2012) Shensi Shen et al. Autophagy
- Guidelines for the use and interpretation of assays for monitoring autophagy
- (2012) Daniel J. Klionsky et al. Autophagy
- Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure
- (2012) Chutima Talchai et al. CELL
- The Inflammasome Puts Obesity in the Danger Zone
- (2012) Rinke Stienstra et al. Cell Metabolism
- Modulation of inflammation by autophagy: consequences for Crohn's disease
- (2012) Theo S Plantinga et al. CURRENT OPINION IN PHARMACOLOGY
- Mapping Autophagy on to Your Metabolic Radar
- (2012) E. Yamada et al. DIABETES
- Stimulation of Autophagy Improves Endoplasmic Reticulum Stress-Induced Diabetes
- (2012) E. Bachar-Wikstrom et al. DIABETES
- Loss of autophagy in hypothalamic POMC neurons impairs lipolysis
- (2012) Susmita Kaushik et al. EMBO REPORTS
- Autophagy Activity Is Up-Regulated in Adipose Tissue of Obese Individuals and Modulates Proinflammatory Cytokine Expression
- (2012) H. J. Jansen et al. ENDOCRINOLOGY
- Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine
- (2012) Kook Hwan Kim et al. NATURE MEDICINE
- Autophagy modulation as a potential therapeutic target for diverse diseases
- (2012) David C. Rubinsztein et al. NATURE REVIEWS DRUG DISCOVERY
- Autophagy in Adipose Tissue
- (2012) Nitzan Maixner et al. Obesity Facts
- Autophagy in adipose tissue biology
- (2012) Yong Zhang et al. PHARMACOLOGICAL RESEARCH
- Palmitate Activates Autophagy in INS-1E β-Cells and in Isolated Rat and Human Pancreatic Islets
- (2012) Luisa Martino et al. PLoS One
- Hypothalamic dysfunction in obesity
- (2012) Lynda M. Williams PROCEEDINGS OF THE NUTRITION SOCIETY
- The PI3K, Metabolic, and Autophagy Networks: Interactive Partners in Cellular Health and Disease
- (2011) Naval P. Shanware et al. Annual Review of Pharmacology and Toxicology
- Liver autophagy contributes to the maintenance of blood glucose and amino acid levels
- (2011) Junji Ezaki et al. Autophagy
- Autophagy regulates inflammation in adipocytes
- (2011) Takeshi Yoshizaki et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- SNARE Proteins Are Required for Macroautophagy
- (2011) Usha Nair et al. CELL
- Autophagy: Renovation of Cells and Tissues
- (2011) Noboru Mizushima et al. CELL
- Autophagy deficiency in beta cells leads to compromised unfolded protein response and progression from obesity to diabetes in mice
- (2011) W. Quan et al. DIABETOLOGIA
- Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β
- (2011) Nicolas Dupont et al. EMBO JOURNAL
- Defective Hypothalamic Autophagy Directs the Central Pathogenesis of Obesity via the IκB Kinase β (IKKβ)/NF-κB Pathway
- (2011) Qingyuan Meng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fatty Acids Suppress Autophagic Turnover in β-Cells
- (2011) Guy Las et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inflammation of the Hypothalamus Leads to Defective Pancreatic Islet Function
- (2011) Vivian C. Calegari et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation
- (2011) James Harris et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autophagy in immunity and inflammation
- (2011) Beth Levine et al. NATURE
- Yin and Yang of hypothalamic insulin and leptin signaling in regulating white adipose tissue metabolism
- (2011) Thomas Scherer et al. REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
- Autophagy in health and disease. 4. The role of pancreatic β-cell autophagy in health and diabetes
- (2010) Yoshio Fujitani et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Mitochondrial degradation by autophagy (mitophagy) in GFP-LC3 transgenic hepatocytes during nutrient deprivation
- (2010) Insil Kim et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- The double-edged effect of autophagy in pancreatic beta cells and diabetes
- (2010) Ze-fang Chen et al. Autophagy
- The emerging role of autophagy in the pathophysiology of diabetes mellitus
- (2010) Claudio D. Gonzalez et al. Autophagy
- Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic β-cells: protective role of p62-positive cytoplasmic inclusions
- (2010) J F Rivera et al. CELL DEATH AND DIFFERENTIATION
- Relation between human LPIN1, hypoxia and endoplasmic reticulum stress genes in subcutaneous and visceral adipose tissue
- (2010) M Miranda et al. INTERNATIONAL JOURNAL OF OBESITY
- Altered Autophagy in Human Adipose Tissues in Obesity
- (2010) Julia Kovsan et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation
- (2010) J.-C. Rodriguez-Prados et al. JOURNAL OF IMMUNOLOGY
- Autophagy and the Integrated Stress Response
- (2010) Guido Kroemer et al. MOLECULAR CELL
- Mutant INS-Gene Induced Diabetes of Youth: Proinsulin Cysteine Residues Impose Dominant-Negative Inhibition on Wild-Type Proinsulin Transport
- (2010) Ming Liu et al. PLoS One
- Innate immunity and adipose tissue biology
- (2010) Andreas Schäffler et al. TRENDS IN IMMUNOLOGY
- Targeted deletion ofautophagy-related 5(atg5) impairs adipogenesis in a cellular model and in mice
- (2009) Rebecca Baerga et al. Autophagy
- Activation of autophagy through modulation of 5′-AMP-activated protein kinase protects pancreatic β-cells from high glucose
- (2009) Diana Han et al. BIOCHEMICAL JOURNAL
- Balancing needs and means: the dilemma of the β-cell in the modern world
- (2009) G. Leibowitz et al. DIABETES OBESITY & METABOLISM
- Autophagy in human type 2 diabetes pancreatic beta cells
- (2009) M. Masini et al. DIABETOLOGIA
- Misfolded Proinsulin Affects Bystander Proinsulin in Neonatal Diabetes
- (2009) Israel Hodish et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autophagy Regulates Pancreatic Beta Cell Death in Response to Pdx1 Deficiency and Nutrient Deprivation
- (2009) Kei Fujimoto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice
- (2009) Anurag Kumar Singh et al. JOURNAL OF CLINICAL INVESTIGATION
- Density functional computational studies on (E)-2-[(2-Hydroxy-5-nitrophenyl)-iminiomethyl]-4-nitrophenolate
- (2009) Hasan Tanak et al. JOURNAL OF MOLECULAR MODELING
- ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery
- (2009) Chang Hwa Jung et al. MOLECULAR BIOLOGY OF THE CELL
- Autophagy regulates lipid metabolism
- (2009) Rajat Singh et al. NATURE
- Glucose Amplifies Fatty Acid-Induced Endoplasmic Reticulum Stress in Pancreatic β-Cells via Activation of mTORC1
- (2009) Etti Bachar et al. PLoS One
- Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis
- (2009) Y. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity
- (2008) Xiaoqing Zhang et al. CELL
- Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia
- (2008) Hye Seung Jung et al. Cell Metabolism
- Autophagy Is Important in Islet Homeostasis and Compensatory Increase of Beta Cell Mass in Response to High-Fat Diet
- (2008) Chie Ebato et al. Cell Metabolism
- mTOR Inhibition by Rapamycin Prevents -Cell Adaptation to Hyperglycemia and Exacerbates the Metabolic State in Type 2 Diabetes
- (2008) M. Fraenkel et al. DIABETES
- Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
- (2008) Gilad Twig et al. EMBO JOURNAL
- The Role for Endoplasmic Reticulum Stress in Diabetes Mellitus
- (2008) Décio L. Eizirik et al. ENDOCRINE REVIEWS
- The Unfolded Protein Response: A Pathway That Links Insulin Demand with β-Cell Failure and Diabetes
- (2008) Donalyn Scheuner et al. ENDOCRINE REVIEWS
- Glucolipotoxicity: Fuel Excess and β-Cell Dysfunction
- (2008) Vincent Poitout et al. ENDOCRINE REVIEWS
- A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
- (2008) Ken Cadwell et al. NATURE
- Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
- (2008) Tatsuya Saitoh et al. NATURE
- Munc 18-1 and Granuphilin Collaborate During Insulin Granule Exocytosis
- (2008) Alejandra Tomas et al. TRAFFIC
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More