Parallel damage in mitochondrial and lysosomal compartments promotes efficient cell death with autophagy: The case of the pentacyclic triterpenoids

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

Betulinic acid and its derivatives: a patent review (2008 – 2013)

(2014) René Csuk   EXPERT OPINION ON THERAPEUTIC PATENTS

Lysosomal membrane permeabilization in cell death: Concepts and challenges

(2014) Urška Repnik et al.   MITOCHONDRION

Betulinic acid-induced mitochondria-dependent cell death is counterbalanced by an autophagic salvage response

(2014) L Potze et al.   Cell Death & Disease

Variants of mitochondrial autophagy: Types 1 and 2 mitophagy and micromitophagy (Type 3)

(2014) John J. Lemasters   Redox Biology

Autophagic flux and oxidative capacity of skeletal muscles during acute starvation

(2013) Mahroo Mofarrahi et al.   Autophagy

Rapid screening of potential autophagic inductor agents using mammalian cell lines

(2013) Waleska K. Martins et al.   Biotechnology Journal

Autophagy and genomic integrity

(2013) A T Vessoni et al.   CELL DEATH AND DIFFERENTIATION

The machinery of macroautophagy

(2013) Yuchen Feng et al.   CELL RESEARCH

Betulinic acid inhibits autophagic flux and induces apoptosis in human multiple myeloma cells in vitro

(2012) Li-jing Yang et al.   ACTA PHARMACOLOGICA SINICA

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Impairment of lysosomal integrity by B10, a glycosylated derivative of betulinic acid, leads to lysosomal cell death and converts autophagy into a detrimental process

(2012) P Gonzalez et al.   CELL DEATH AND DIFFERENTIATION

Investigation of the interactions of lupane type pentacyclic triterpenes with outer leaflet membrane phospholipids – Langmuir monolayer and synchrotron X-ray scattering study

(2012) Marcin Broniatowski et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Sensitivity to Lysosome-Dependent Cell Death Is Directly Regulated by Lysosomal Cholesterol Content

(2012) Hanna Appelqvist et al.   PLoS One

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Oleanolic Acid Initiates Apoptosis in Non-Small Cell Lung Cancer Cell Lines and Reduces Metastasis of a B16F10 Melanoma Model In Vivo

(2011) Kelly Araújo Lúcio et al.   PLoS One

Autophagy in human keratinocytes: an early step of the differentiation?

(2010) Elodie Aymard et al.   EXPERIMENTAL DERMATOLOGY

Nix Is Critical to Two Distinct Phases of Mitophagy, Reactive Oxygen Species-mediated Autophagy Induction and Parkin-Ubiquitin-p62-mediated Mitochondrial Priming

(2010) Wen-Xing Ding et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monolayer behavior of binary systems of betulinic acid and cardiolipin: Thermodynamic analyses of Langmuir monolayers and AFM study of Langmuir–Blodgett monolayers

(2010) Yingying Chen et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Mitochondrial Turnover and Aging of Long-Lived Postmitotic Cells: The Mitochondrial–Lysosomal Axis Theory of Aging

(2009) Alexei Terman et al.   ANTIOXIDANTS & REDOX SIGNALING

Betulinic acid induces cytochrome c release and apoptosis in a Bax/Bak-independent, permeability transition pore dependent fashion

(2009) Franziska B. Mullauer et al.   APOPTOSIS

Targeting mitochondrial apoptosis by betulinic acid in human cancers

(2009) Simone Fulda et al.   DRUG DISCOVERY TODAY

On the Validation of Molecular Dynamics Simulations of Saturated andcis-Monounsaturated Phosphatidylcholine Lipid Bilayers: A Comparison with Experiment

(2009) David Poger et al.   Journal of Chemical Theory and Computation

Pentacyclic Triterpenes of the Lupane, Oleanane and Ursane Group as Tools in Cancer Therapy

(2009) Melanie Laszczyk   PLANTA MEDICA

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

Ursolic, oleanolic and betulinic acids: Antibacterial spectra and selectivity indexes

(2008) Stéphane Fontanay et al.   JOURNAL OF ETHNOPHARMACOLOGY

Betulinic acid: A natural product with anticancer activity

(2008) Simone Fulda   MOLECULAR NUTRITION & FOOD RESEARCH

Autophagic cell death: the story of a misnomer

(2008) Guido Kroemer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY