Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development
出版年份 2019 全文链接
标题
Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development
作者
关键词
-
出版物
Oxidative Medicine and Cellular Longevity
Volume 2019, Issue -, Pages 1-20
出版商
Hindawi Limited
发表日期
2019-07-15
DOI
10.1155/2019/9372182
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases
- (2019) Antonio Cuadrado et al. NATURE REVIEWS DRUG DISCOVERY
- CXA-10, a Nitrated Fatty Acid, is Renoprotective in Deoxycorticosterone Acetate-Salt Nephropathy
- (2019) Cynthia Arbeeny et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- NRF2 and the Hallmarks of Cancer
- (2018) Montserrat Rojo de la Vega et al. CANCER CELL
- NRF2 addiction in cancer cells
- (2018) Hiroshi Kitamura et al. CANCER SCIENCE
- Targeted Nrf2 activation therapy with RTA 408 enhances regenerative capacity of diabetic wounds
- (2018) Piul S. Rabbani et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Discovery of a head-to-tail cyclic peptide as the Keap1-Nrf2 protein-protein interaction inhibitor with high cell potency
- (2018) Meng-Chen Lu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Glycogen synthase kinase-3 and its inhibitors: Potential target for various therapeutic conditions
- (2018) A. Prasanth Saraswati et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Epigenetic versus Genetic Deregulation of the KEAP1/NRF2 Axis in Solid Tumors: Focus on Methylation and Noncoding RNAs
- (2018) F. P. Fabrizio et al. Oxidative Medicine and Cellular Longevity
- Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach
- (2018) Antonio Cuadrado et al. PHARMACOLOGICAL REVIEWS
- C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape
- (2018) Sharadha Dayalan Naidu et al. Scientific Reports
- Dimethyl fumarate downregulates the immune response through the HCA 2 /GPR109A pathway: Implications for the treatment of multiple sclerosis
- (2018) Felipe von Glehn et al. Multiple Sclerosis and Related Disorders
- Emerging Understanding of the Mechanism of Action for Dimethyl Fumarate in the Treatment of Multiple Sclerosis
- (2018) Elizabeth A. Mills et al. Frontiers in Neurology
- Trehalose protects against oxidative stress by regulating the Keap1–Nrf2 and autophagy pathways
- (2018) Yuhei Mizunoe et al. Redox Biology
- Replacement of a Naphthalene Scaffold in Kelch-like ECH-Associated Protein 1 (KEAP1)/Nuclear Factor (Erythroid-derived 2)-like 2 (NRF2) Inhibitors
- (2018) Benjamin G. Richardson et al. JOURNAL OF MEDICINAL CHEMISTRY
- Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
- (2018) Evanna L. Mills et al. NATURE
- Regulation of the NRF2 transcription factor by andrographolide and organic extracts from plant endophytes
- (2018) Daphne Pei Wen Wong et al. PLoS One
- MicroRNA-98-5p ameliorates oxygen-glucose deprivation/reoxygenation (OGD/R)-induced neuronal injury by inhibiting Bach1 and promoting Nrf2/ARE signaling
- (2018) Xiuyan Sun et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Safety, pharmacodynamics, and potential benefit of omaveloxolone in Friedreich ataxia
- (2018) David R. Lynch et al. Annals of Clinical and Translational Neurology
- The novel Nrf2 inducer TFM-735 ameliorates experimental autoimmune encephalomyelitis in mice
- (2017) Chika Higashi et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Recent progress in the development of small molecule Nrf2 modulators: a patent review (2012-2016)
- (2017) Haopeng Sun et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Halofuginone enhances the chemo-sensitivity of cancer cells by suppressing NRF2 accumulation
- (2017) Kouhei Tsuchida et al. FREE RADICAL BIOLOGY AND MEDICINE
- Stress-sensing mechanisms and the physiological roles of the Keap1–Nrf2 system during cellular stress
- (2017) Takafumi Suzuki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of a novel series of anti-inflammatory and anti-oxidative phospholipid oxidation products containing the cyclopentenone moietyin vitroandin vivo: Implication in atherosclerosis
- (2017) Jianhong Lu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Characterization of the Potent, Selective Nrf2 Activator, 3-(Pyridin-3-Ylsulfonyl)-5-(Trifluoromethyl)-2 H -Chromen-2-One, in Cellular and In Vivo Models of Pulmonary Oxidative Stress
- (2017) John G. Yonchuk et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- 15-Deoxy-Δ12,14-prostaglandin J2 Exerts Antioxidant Effects While Exacerbating Inflammation in Mice Subjected to Ureteral Obstruction
- (2017) Line Nilsson et al. MEDIATORS OF INFLAMMATION
- Brusatol overcomes chemoresistance through inhibition of protein translation
- (2017) Bryan Harder et al. MOLECULAR CARCINOGENESIS
- A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer
- (2017) E-J Choi et al. ONCOGENE
- Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes
- (2017) Annika S. Axelsson et al. Science Translational Medicine
- Controversy about pharmacological modulation of Nrf2 for cancer therapy
- (2017) Lidija Milkovic et al. Redox Biology
- Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases
- (2017) Marta Pajares et al. Redox Biology
- Dimethyl fumarate alters B-cell memory and cytokine production in MS patients
- (2017) Matthew D. Smith et al. Annals of Clinical and Translational Neurology
- Small Molecule Inhibitor of NRF2 Selectively Intervenes Therapeutic Resistance in KEAP1-Deficient NSCLC Tumors
- (2016) Anju Singh et al. ACS Chemical Biology
- Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes
- (2016) Marta Pajares et al. Autophagy
- Thermodynamic profiling of inhibitors of Nrf2:Keap1 interactions
- (2016) Hamid R. Nasiri et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Glycogen synthase kinase 3 (GSK-3) inhibitors: a patent update (2014-2015)
- (2016) Valle Palomo et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy
- (2016) Jiayu Zhu et al. FREE RADICAL BIOLOGY AND MEDICINE
- Overdose Intake of Curcumin Initiates the Unbalanced State of Bodies
- (2016) Peiyu Qiu et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Dimethyl Fumarate Treatment Mediates an Anti-Inflammatory Shift in B Cell Subsets of Patients with Multiple Sclerosis
- (2016) Rui Li et al. JOURNAL OF IMMUNOLOGY
- Design and Synthesis of Irreversible Analogues of Bardoxolone Methyl for the Identification of Pharmacologically Relevant Targets and Interaction Sites
- (2016) Michael H. L. Wong et al. JOURNAL OF MEDICINAL CHEMISTRY
- Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein–Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery
- (2016) Thomas G. Davies et al. JOURNAL OF MEDICINAL CHEMISTRY
- Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells
- (2016) Tatsuro Iso et al. MOLECULAR AND CELLULAR BIOLOGY
- Sulforaphane and Other Nutrigenomic Nrf2 Activators: Can the Clinician’s Expectation Be Matched by the Reality?
- (2016) Christine A. Houghton et al. Oxidative Medicine and Cellular Longevity
- Discovery of a novel Nrf2 inhibitor that induces apoptosis of human acute myeloid leukemia cells
- (2016) JinFeng Zhang et al. Oncotarget
- A Small Molecule Inhibits Deregulated NRF2 Transcriptional Activity in Cancer
- (2015) Michael J. Bollong et al. ACS Chemical Biology
- Non-electrophilic modulators of the canonical Keap1/Nrf2 pathway
- (2015) B.G. Richardson et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Melatonin-sulforaphane hybrid ITH12674 induces neuroprotection in oxidative stress conditions by a ‘drug-prodrug’ mechanism of action
- (2015) Javier Egea et al. BRITISH JOURNAL OF PHARMACOLOGY
- Structural and functional characterization of Nrf2 degradation by glycogen synthase kinase 3/β-TrCP
- (2015) Antonio Cuadrado FREE RADICAL BIOLOGY AND MEDICINE
- Activation of NRF2 Signaling in HEK293 Cells by a First-in-Class Direct KEAP1-NRF2 Inhibitor
- (2015) Xia Wen et al. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
- Structure–Activity and Structure–Property Relationship and Exploratory in Vivo Evaluation of the Nanomolar Keap1–Nrf2 Protein–Protein Interaction Inhibitor
- (2015) Zheng-Yu Jiang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Design, Synthesis, and Evaluation of Triazole Derivatives That Induce Nrf2 Dependent Gene Products and Inhibit the Keap1–Nrf2 Protein–Protein Interaction
- (2015) Hélène C. Bertrand et al. JOURNAL OF MEDICINAL CHEMISTRY
- Cell-Permeable Peptide Targeting the Nrf2-Keap1 Interaction: A Potential Novel Therapy for Global Cerebral Ischemia
- (2015) J. Tu et al. JOURNAL OF NEUROSCIENCE
- Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis
- (2015) Steffan Vartanian et al. MOLECULAR & CELLULAR PROTEOMICS
- Characterizations of Three Major Cysteine Sensors of Keap1 in Stress Response
- (2015) Ryota Saito et al. MOLECULAR AND CELLULAR BIOLOGY
- The variable chemotherapeutic response of Malabaricone-A in leukemic and solid tumor cell lines depends on the degree of redox imbalance
- (2015) Alak Manna et al. PHYTOMEDICINE
- Redox control of protein degradation
- (2015) Marta Pajares et al. Redox Biology
- Alzheimer's disease, enzyme targets and drug discovery struggles: From natural products to drug prototypes
- (2014) Tiago Silva et al. AGEING RESEARCH REVIEWS
- Oncogenic KRAS Confers Chemoresistance by Upregulating NRF2
- (2014) S. Tao et al. CANCER RESEARCH
- Binding Mode and Structure-Activity Relationships around Direct Inhibitors of the Nrf2-Keap1 Complex
- (2014) Eric Jnoff et al. ChemMedChem
- Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis
- (2014) T. Wu et al. GENES & DEVELOPMENT
- Discovery of Potent Keap1–Nrf2 Protein–Protein Interaction Inhibitor Based on Molecular Binding Determinants Analysis
- (2014) Zheng-Yu Jiang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structure of the BTB Domain of Keap1 and Its Interaction with the Triterpenoid Antagonist CDDO
- (2014) Anne Cleasby et al. PLoS One
- Induction of Heme Oxygenase I (HMOX1) by HPP-4382: A Novel Modulator of Bach1 Activity
- (2014) Otis C. Attucks et al. PLoS One
- The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
- (2014) John D. Hayes et al. TRENDS IN BIOCHEMICAL SCIENCES
- Selective inhibition of bacterial topoisomerase I by alkynyl-bisbenzimidazoles
- (2014) Nihar Ranjan et al. MedChemComm
- A Review of the Evidence that Ochratoxin A Is an Nrf2 Inhibitor: Implications for Nephrotoxicity and Renal Carcinogenicity
- (2014) Alice Limonciel et al. Toxins
- Role of Nrf2 in Oxidative Stress and Toxicity
- (2013) Qiang Ma Annual Review of Pharmacology and Toxicology
- Detection of fumarate–glutathione adducts in the portal vein blood of rats: evidence for rapid dimethylfumarate metabolism
- (2013) Stefan Dibbert et al. ARCHIVES OF DERMATOLOGICAL RESEARCH
- Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism
- (2013) Douglas Marcotte et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Discovery of a small-molecule inhibitor and cellular probe of Keap1–Nrf2 protein–protein interaction
- (2013) Longqin Hu et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Proteomic Analysis of Ubiquitin Ligase KEAP1 Reveals Associated Proteins That Inhibit NRF2 Ubiquitination
- (2013) B. E. Hast et al. CANCER RESEARCH
- RXR Inhibits the NRF2-ARE Signaling Pathway through a Direct Interaction with the Neh7 Domain of NRF2
- (2013) H. Wang et al. CANCER RESEARCH
- Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs
- (2013) Takumi Satoh et al. FREE RADICAL BIOLOGY AND MEDICINE
- Keap Calm, and Carry on Covalently
- (2013) Anthony J. Wilson et al. JOURNAL OF MEDICINAL CHEMISTRY
- Reduction of atherogenic risk in patients with type 2 diabetes by curcuminoid extract: a randomized controlled trial
- (2013) Somlak Chuengsamarn et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Peptide inhibitors of the Keap1–Nrf2 protein–protein interaction with improved binding and cellular activity
- (2013) Rowena Hancock et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Sulforaphane as a Potential Protective Phytochemical against Neurodegenerative Diseases
- (2013) Andrea Tarozzi et al. Oxidative Medicine and Cellular Longevity
- Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex
- (2013) L. Baird et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Luteolin, a bioflavonoid inhibits Azoxymethane-induced colorectal cancer through activation of Nrf2 signaling
- (2013) Ashok Kumar Pandurangan et al. TOXICOLOGY MECHANISMS AND METHODS
- Toward clinical application of the Keap1–Nrf2 pathway
- (2013) Takafumi Suzuki et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Novel protein–protein interaction inhibitor of Nrf2–Keap1 discovered by structure-based virtual screening
- (2013) Hao-Peng Sun et al. MedChemComm
- Amelioration of Alzheimer’s disease by neuroprotective effect of sulforaphane in animal model
- (2012) Hyunjin Vincent Kim et al. AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS
- Bardoxolone Brings Nrf2-Based Therapies to Light
- (2012) Donna D. Zhang ANTIOXIDANTS & REDOX SIGNALING
- The high Nrf2 expression in human acute myeloid leukemia is driven by NF- B and underlies its chemo-resistance
- (2012) S. A. Rushworth et al. BLOOD
- Broccoli sprouts powder could improve serum triglyceride and oxidized LDL/LDL-cholesterol ratio in type 2 diabetic patients: A randomized double-blind placebo-controlled clinical trial
- (2012) Zahra Bahadoran et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Small Molecule Modulators of Keap1-Nrf2-ARE Pathway as Potential Preventive and Therapeutic Agents
- (2012) Sadagopan Magesh et al. MEDICINAL RESEARCH REVIEWS
- Structural and Functional Characterization of Nrf2 Degradation by the Glycogen Synthase Kinase 3/ -TrCP Axis
- (2012) P. Rada et al. MOLECULAR AND CELLULAR BIOLOGY
- Drug resistance associates with activation of Nrf2 in MCF-7/DOX cells, and wogonin reverses it by down-regulating Nrf2-mediated cellular defense response
- (2012) Yan Zhong et al. MOLECULAR CARCINOGENESIS
- Curcuminoids exert glucose-lowering effect in type 2 diabetes by decreasing serum free fatty acids: a double-blind, placebo-controlled trial
- (2012) Li-Xin Na et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Placebo-Controlled Phase 3 Study of Oral BG-12 or Glatiramer in Multiple Sclerosis
- (2012) Robert J. Fox et al. NEW ENGLAND JOURNAL OF MEDICINE
- Placebo-Controlled Phase 3 Study of Oral BG-12 for Relapsing Multiple Sclerosis
- (2012) Ralf Gold et al. NEW ENGLAND JOURNAL OF MEDICINE
- Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression and proteasome activity
- (2012) A Arlt et al. ONCOGENE
- Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity
- (2012) S Chowdhry et al. ONCOGENE
- Anti-inflammatory Effect of a Cell-Penetrating Peptide Targeting the Nrf2/Keap1 Interaction
- (2012) Richard Steel et al. ACS Medicinal Chemistry Letters
- Pharmacological Targeting of the Transcription Factor Nrf2 at the Basal Ganglia Provides Disease Modifying Therapy for Experimental Parkinsonism
- (2011) Agnieszka Jazwa et al. ANTIOXIDANTS & REDOX SIGNALING
- Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway
- (2011) Ralf A. Linker et al. BRAIN
- MiR-28 regulates Nrf2 expression through a Keap1-independent mechanism
- (2011) Muhua Yang et al. BREAST CANCER RESEARCH AND TREATMENT
- Kinetic Analyses of Keap1-Nrf2 Interaction and Determination of the Minimal Nrf2 Peptide Sequence Required for Keap1 Binding Using Surface Plasmon Resonance
- (2011) Yu Chen et al. Chemical Biology & Drug Design
- Luteolin inhibits Nrf2 leading to negative regulation of the Nrf2/ARE pathway and sensitization of human lung carcinoma A549 cells to therapeutic drugs
- (2011) Xiuwen Tang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Peptide inhibitors of the Keap1–Nrf2 protein–protein interaction
- (2011) Rowena Hancock et al. FREE RADICAL BIOLOGY AND MEDICINE
- Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability: Role of glycogen synthase kinase-3
- (2011) Ana I. Rojo et al. FREE RADICAL BIOLOGY AND MEDICINE
- Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution
- (2011) Keiko Taguchi et al. GENES TO CELLS
- Electrophilic Nitro-fatty Acids Activate NRF2 by a KEAP1 Cysteine 151-independent Mechanism
- (2011) Emilia Kansanen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
- (2011) Gina M. DeNicola et al. NATURE
- Bardoxolone Methyl and Kidney Function in CKD with Type 2 Diabetes
- (2011) Pablo E. Pergola et al. NEW ENGLAND JOURNAL OF MEDICINE
- Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism
- (2011) D. Ren et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enhanced Hepatic Nrf2 Activation After Ursodeoxycholic Acid Treatment in Patients with Primary Biliary Cirrhosis
- (2010) Kazuhito Kawata et al. ANTIOXIDANTS & REDOX SIGNALING
- microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease
- (2010) C. Sangokoya et al. BLOOD
- Sulforaphane protects brains against hypoxic–ischemic injury through induction of Nrf2-dependent phase 2 enzyme
- (2010) Zhang Ping et al. BRAIN RESEARCH
- Activation of the NRF2 Signaling Pathway by Copper-Mediated Redox Cycling of Para- and Ortho-Hydroquinones
- (2010) Xiu Jun Wang et al. CHEMISTRY & BIOLOGY
- Nrf2 and Keap1 Abnormalities in Non-Small Cell Lung Carcinoma and Association with Clinicopathologic Features
- (2010) L. M. Solis et al. CLINICAL CANCER RESEARCH
- Small molecule modulators of antioxidant response pathway
- (2010) Wooyoung Hur et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Activation of NRF2 by Nitrosative Agents and H2O2Involves KEAP1 Disulfide Formation
- (2010) Simon Fourquet et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription
- (2010) Ashish Jain et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction between Keap1 and p62
- (2010) A. Lau et al. MOLECULAR AND CELLULAR BIOLOGY
- The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
- (2010) Masaaki Komatsu et al. NATURE CELL BIOLOGY
- GSK3 signalling in neural development
- (2010) Eun-Mi Hur et al. NATURE REVIEWS NEUROSCIENCE
- Protection against amyloid beta cytotoxicity by sulforaphane: Role of the proteasome
- (2009) Hyun-Min Park et al. ARCHIVES OF PHARMACAL RESEARCH
- Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice
- (2008) Kosuke Okada et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Glycogen synthase kinase 3β (GSK3β) in tumorigenesis and cancer chemotherapy
- (2008) Jia Luo CANCER LETTERS
- Loss of Keap1 Function Activates Nrf2 and Provides Advantages for Lung Cancer Cell Growth
- (2008) T. Ohta et al. CANCER RESEARCH
- Curcumin: From ancient medicine to current clinical trials
- (2008) H. Hatcher et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Prospective Type 1 and Type 2 Disulfides of Keap1 Protein
- (2008) Ryan Holland et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Physiological Significance of Reactive Cysteine Residues of Keap1 in Determining Nrf2 Activity
- (2008) T. Yamamoto et al. MOLECULAR AND CELLULAR BIOLOGY
- Small molecule enhancers of autophagy for neurodegenerative diseases
- (2008) Sovan Sarkar et al. Molecular BioSystems
- Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy
- (2008) T. Shibata et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now