Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution
出版年份 2011 全文链接
标题
Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution
作者
关键词
-
出版物
GENES TO CELLS
Volume 16, Issue 2, Pages 123-140
出版商
Wiley
发表日期
2011-01-21
DOI
10.1111/j.1365-2443.2010.01473.x
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- High Levels of Nrf2 Determine Chemoresistance in Type II Endometrial Cancer
- (2010) T. Jiang et al. CANCER RESEARCH
- Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung
- (2010) Hironori Satoh et al. CARCINOGENESIS
- Physiological significance of selective degradation of p62 by autophagy
- (2010) Masaaki Komatsu et al. FEBS LETTERS
- Physical and Functional Interaction of Sequestosome 1 with Keap1 Regulates the Keap1-Nrf2 Cell Defense Pathway
- (2010) Ian M. Copple et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription
- (2010) Ashish Jain et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Critical Role of Nitric Oxide Signaling, via ProteinS-Guanylation and Nitrated Cyclic GMP, in the Antioxidant Adaptive Response
- (2010) Shigemoto Fujii et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genetic Analysis of Cytoprotective Functions Supported by Graded Expression of Keap1
- (2010) K. Taguchi et al. MOLECULAR AND CELLULAR BIOLOGY
- A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction between Keap1 and p62
- (2010) A. Lau et al. MOLECULAR AND CELLULAR BIOLOGY
- Loss of Kelch-Like ECH-Associated Protein 1 Function in Prostate Cancer Cells Causes Chemoresistance and Radioresistance and Promotes Tumor Growth
- (2010) P. Zhang et al. MOLECULAR CANCER THERAPEUTICS
- Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains
- (2010) T. Ogura et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1
- (2009) Aimee L. Eggler et al. BIOCHEMICAL JOURNAL
- Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice
- (2009) Melinda S. Yates et al. CARCINOGENESIS
- Nrf2 Enhances Cell Proliferation and Resistance to Anticancer Drugs in Human Lung Cancer
- (2009) S. Homma et al. CLINICAL CANCER RESEARCH
- Oncogenic NRF2 mutations in squamous cell carcinomas of oesophagus and skin
- (2009) Yoo Ri Kim et al. JOURNAL OF PATHOLOGY
- Direct Interaction between Nrf2 and p21Cip1/WAF1 Upregulates the Nrf2-Mediated Antioxidant Response
- (2009) Weimin Chen et al. MOLECULAR CELL
- Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases
- (2009) Min Zhuang et al. MOLECULAR CELL
- Phosphorylation of Nrf2 at Multiple Sites by MAP Kinases Has a Limited Contribution in Modulating the Nrf2-Dependent Antioxidant Response
- (2009) Zheng Sun et al. PLoS One
- Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents
- (2009) Larry G. Higgins et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Cysteine-based regulation of the CUL3 adaptor protein Keap1
- (2009) Konjeti R. Sekhar et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Comprehensive proteomics analysis of autophagy-deficient mouse liver
- (2008) Naomi Matsumoto et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Hypermethylation of the Keap1 gene in human lung cancer cell lines and lung cancer tissues
- (2008) Rui Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mallory–Denk-bodies: Lessons from keratin-containing hepatic inclusion bodies
- (2008) P. Strnad et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Loss of Keap1 Function Activates Nrf2 and Provides Advantages for Lung Cancer Cell Growth
- (2008) T. Ohta et al. CANCER RESEARCH
- RNAi-Mediated Silencing of Nuclear Factor Erythroid-2-Related Factor 2 Gene Expression in Non-Small Cell Lung Cancer Inhibits Tumor Growth and Increases Efficacy of Chemotherapy
- (2008) A. Singh et al. CANCER RESEARCH
- Prospective Type 1 and Type 2 Disulfides of Keap1 Protein
- (2008) Ryan Holland et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Covalent Modification at Cys151 Dissociates the Electrophile Sensor Keap1 from the Ubiquitin Ligase CUL3
- (2008) Girish Rachakonda et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Genetic Alteration of Keap1 Confers Constitutive Nrf2 Activation and Resistance to Chemotherapy in Gallbladder Cancer
- (2008) Tatsuhiro Shibata et al. GASTROENTEROLOGY
- Structural insights into the similar modes of Nrf2 transcription factor recognition by the cytoplasmic repressor Keap1
- (2008) Balasundaram Padmanabhan et al. JOURNAL OF SYNCHROTRON RADIATION
- Physiological Significance of Reactive Cysteine Residues of Keap1 in Determining Nrf2 Activity
- (2008) T. Yamamoto et al. MOLECULAR AND CELLULAR BIOLOGY
- The Antioxidant Defense System Keap1-Nrf2 Comprises a Multiple Sensing Mechanism for Responding to a Wide Range of Chemical Compounds
- (2008) M. Kobayashi et al. MOLECULAR AND CELLULAR BIOLOGY
- Treatment of arthritis with a selective inhibitor of c-Fos/activator protein-1
- (2008) Yukihiko Aikawa et al. NATURE BIOTECHNOLOGY
- Nrf2 as a Master Redox Switch in Turning on the Cellular Signaling Involved in the Induction of Cytoprotective Genes by Some Chemopreventive Phytochemicals
- (2008) Young-Joon Surh et al. PLANTA MEDICA
- Targeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice
- (2008) T. E. Sussan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy
- (2008) T. Shibata et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Carnosic acid, acatechol-typeelectrophilic compound, protects neurons bothin vitroandin vivothrough activation of the Keap1/Nrf2 pathway viaS-alkylation of targeted cysteines on Keap1
- (2007) Takumi Satoh et al. JOURNAL OF NEUROCHEMISTRY
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