Peripheral-Central Neuroimmune Crosstalk in Parkinson's Disease: What Do Patients and Animal Models Tell Us?
出版年份 2019 全文链接
标题
Peripheral-Central Neuroimmune Crosstalk in Parkinson's Disease: What Do Patients and Animal Models Tell Us?
作者
关键词
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出版物
Frontiers in Neurology
Volume 10, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2019-03-19
DOI
10.3389/fneur.2019.00232
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- 5-(3,4-Difluorophenyl)−3-(6-methylpyridin-3-yl)−1,2,4-oxadiazole (DDO-7263), a Novel Nrf2 Activator Targeting Brain Tissue, Protects Against MPTP-induced Subacute Parkinson's Disease in Mice by Inhibiting the NLRP3 Inflammasome and Protects PC12 Cells Against Oxidative Stress
- (2019) Li-Li Xu et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mutant LRRK2 mediates peripheral and central immune responses leading to neurodegeneration in vivo
- (2018) Elena Kozina et al. BRAIN
- Interleukin-1β, interleukin-1 receptor antagonist, interleukin-6, interleukin-10, and tumor necrosis factor-α levels in CSF and serum in relation to the clinical diversity of Parkinson’s disease
- (2018) M.N. Karpenko et al. CELLULAR IMMUNOLOGY
- Inflammatory bowel disease increases the risk of Parkinson’s disease: a Danish nationwide cohort study 1977–2014
- (2018) Marie Villumsen et al. GUT
- Curcumin Suppresses IL-1β Secretion and Prevents Inflammation through Inhibition of the NLRP3 Inflammasome
- (2018) Haipeng Yin et al. JOURNAL OF IMMUNOLOGY
- Inhibition of the hepatic Nlrp3 protects dopaminergic neurons via attenuating systemic inflammation in a MPTP/p mouse model of Parkinson’s disease
- (2018) Chen Qiao et al. Journal of Neuroinflammation
- Parkinson’s disease patients have a complex phenotypic and functional Th1 bias: cross-sectional studies of CD4+ Th1/Th2/T17 and Treg in drug-naïve and drug-treated patients
- (2018) Natasa Kustrimovic et al. Journal of Neuroinflammation
- (-)-Epigallocatechin-3-gallate modulates peripheral immunity in the MPTP-induced mouse model of Parkinson's disease
- (2018) Tingting Zhou et al. Molecular Medicine Reports
- Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease
- (2018) Seung Pil Yun et al. NATURE MEDICINE
- Microglial immune checkpoint mechanisms
- (2018) Aleksandra Deczkowska et al. NATURE NEUROSCIENCE
- A Combination of Ontogeny and CNS Environment Establishes Microglial Identity
- (2018) F. Chris Bennett et al. NEURON
- IL-1β enables CNS access to CCR2himonocytes and the generation of pathogenic cells through GM-CSF released by CNS endothelial cells
- (2018) Alexandre Paré et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional variants in the LRRK2 gene confer shared effects on risk for Crohn’s disease and Parkinson’s disease
- (2018) Ken Y. Hui et al. Science Translational Medicine
- What Effects Might Exenatide have on Non-Motor Symptoms in Parkinson’s Disease: A Post Hoc Analysis
- (2018) Dilan Athauda et al. Journal of Parkinsons Disease
- Anti–Tumor Necrosis Factor Therapy and Incidence of Parkinson Disease Among Patients With Inflammatory Bowel Disease
- (2018) Inga Peter et al. JAMA Neurology
- Neuroinflammation: Microglia and T Cells Get Ready to Tango
- (2018) Sjoerd T. T. Schetters et al. Frontiers in Immunology
- Post hoc analysis of the Exenatide-PD trial - factors that predict response
- (2018) Dilan Athauda et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Tetracycline repurposing in neurodegeneration: focus on Parkinson’s disease
- (2018) Mariza Bortolanza et al. JOURNAL OF NEURAL TRANSMISSION
- Nonsteroidal anti-inflammatory drugs use and risk of Parkinson disease
- (2018) Li Ren et al. MEDICINE
- Is constipation in Parkinson's disease caused by gut or brain pathology?
- (2018) Per Borghammer PARKINSONISM & RELATED DISORDERS
- Microglia Response During Parkinson’s Disease: Alpha-Synuclein Intervention
- (2018) Sara A. Ferreira et al. Frontiers in Cellular Neuroscience
- A monocyte gene expression signature in the early clinical course of Parkinson’s disease
- (2018) Johannes C. M. Schlachetzki et al. Scientific Reports
- Cerebrospinal fluid concentrations of inflammatory markers in Parkinson’s disease and atypical parkinsonian disorders
- (2018) Sara Hall et al. Scientific Reports
- Interleukin-4 Contributes to Degeneration of Dopamine Neurons in the Lipopolysaccharide-treated Substantia Nigra in vivo
- (2018) Eugene Bok et al. Experimental Neurobiology
- The role of LRRK2 in cell signalling
- (2018) Kirsten Harvey et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Non-steroidal anti-inflammatory drugs and risk of Parkinson’s disease in the elderly population: a meta-analysis
- (2018) Tahmina Nasrin Poly et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Genetically engineered animal models of Parkinson's disease: from worm to rodent
- (2018) Ludivine S Breger et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- PET imaging of [11C]PBR28 in Parkinson’s disease patients does not indicate increased binding to TSPO despite reduced dopamine transporter binding
- (2018) Katarina Varnäs et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Can the gut be the missing piece in uncovering PD pathogenesis?
- (2018) Guillaume Chapelet et al. PARKINSONISM & RELATED DISORDERS
- Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson’s Disease
- (2018) Irene García-Domínguez et al. Frontiers in Cellular Neuroscience
- The Gut and Parkinson’s Disease: Hype or Hope?
- (2018) Filip Scheperjans et al. Journal of Parkinsons Disease
- Immune Cell Activation in the Cerebrospinal Fluid of Patients With Parkinson's Disease
- (2018) Jens B. Schröder et al. Frontiers in Neurology
- Genipin protects d -galactosamine and lipopolysaccharide-induced hepatic injury through suppression of the necroptosis-mediated inflammasome signaling
- (2017) Min-Jong Seo et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Myeloid Cells in the Central Nervous System
- (2017) Jasmin Herz et al. IMMUNITY
- Structural and physiological neurovascular changes in idiopathic Parkinson’s disease and its clinical phenotypes
- (2017) Sarah Al-Bachari et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Induction of Adaptive Immunity Leads to Nigrostriatal Disease Progression in MPTP Mouse Model of Parkinson’s Disease
- (2017) Goutam Chandra et al. JOURNAL OF IMMUNOLOGY
- Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson’s disease
- (2017) Lori N. Eidson et al. Journal of Neuroinflammation
- Analysis of monocyte infiltration in MPTP mice reveals that microglial CX3CR1 protects against neurotoxic over-induction of monocyte-attracting CCL2 by astrocytes
- (2017) Vincent R. Parillaud et al. Journal of Neuroinflammation
- Prying into the Prion Hypothesis for Parkinson's Disease
- (2017) Patrik Brundin et al. JOURNAL OF NEUROSCIENCE
- Exenatide once weekly versus placebo in Parkinson's disease: a randomised, double-blind, placebo-controlled trial
- (2017) Dilan Athauda et al. LANCET
- A new fate mapping system reveals context-dependent random or clonal expansion of microglia
- (2017) Tuan Leng Tay et al. NATURE NEUROSCIENCE
- High-dimensional, single-cell characterization of the brain's immune compartment
- (2017) Ben Korin et al. NATURE NEUROSCIENCE
- Early upregulation of 18-kDa translocator protein in response to acute neurodegenerative damage in TREM2-deficient mice
- (2017) Sara Belloli et al. NEUROBIOLOGY OF AGING
- Alternative microglial activation is associated with cessation of progressive dopamine neuron loss in mice systemically administered lipopolysaccharide
- (2017) Eric E. Beier et al. NEUROBIOLOGY OF DISEASE
- The NLRP3 Inflammasome is Involved in the Pathogenesis of Parkinson’s Disease in Rats
- (2017) Zhijuan Mao et al. NEUROCHEMICAL RESEARCH
- The correlation of lymphocyte subsets, natural killer cell, and Parkinson’s disease: a meta-analysis
- (2017) Sen Jiang et al. NEUROLOGICAL SCIENCES
- An altered blood–brain barrier contributes to brain iron accumulation and neuroinflammation in the 6-OHDA rat model of Parkinson’s disease
- (2017) Sonia Olmedo-Díaz et al. NEUROSCIENCE
- Complex Changes in the Innate and Adaptive Immunity Accompany Progressive Degeneration of the Nigrostriatal Pathway Induced by Intrastriatal Injection of 6-Hydroxydopamine in the Rat
- (2017) Giulia Ambrosi et al. NEUROTOXICITY RESEARCH
- Microglial phenotypes in Parkinson’s disease and animal models of the disease
- (2017) Valerie Joers et al. PROGRESS IN NEUROBIOLOGY
- Editor’s Highlight: Nlrp3 Is Required for Inflammatory Changes and Nigral Cell Loss Resulting From Chronic Intragastric Rotenone Exposure in Mice
- (2017) Eileen M. Martinez et al. TOXICOLOGICAL SCIENCES
- Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain
- (2017) Katharine Askew et al. Cell Reports
- Influence of Estrogen Modulation on Glia Activation in a Murine Model of Parkinson's Disease
- (2017) Francesca Siani et al. Frontiers in Neuroscience
- Parkinson's disease-associated genetic variation is linked to quantitative expression of inflammatory genes
- (2017) Steven Pierce et al. PLoS One
- Quercetin Inhibits Inflammasome Activation by Interfering with ASC Oligomerization and Prevents Interleukin-1 Mediated Mouse Vasculitis
- (2017) Talita P. Domiciano et al. Scientific Reports
- Neutralization of RANTES and Eotaxin Prevents the Loss of Dopaminergic Neurons in a Mouse Model of Parkinson Disease
- (2016) Goutam Chandra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- How can rAAV-α-synuclein and the fibril α-synuclein models advance our understanding of Parkinson's disease?
- (2016) Laura A. Volpicelli-Daley et al. JOURNAL OF NEUROCHEMISTRY
- Neuroinflammation: the devil is in the details
- (2016) Damon J. DiSabato et al. JOURNAL OF NEUROCHEMISTRY
- Mitochondrial dysfunction in Parkinson's disease
- (2016) Anindita Bose et al. JOURNAL OF NEUROCHEMISTRY
- Microglia across the lifespan: from origin to function in brain development, plasticity and cognition
- (2016) Tuan Leng Tay et al. JOURNAL OF PHYSIOLOGY-LONDON
- Caspase-1 Deficiency Alleviates Dopaminergic Neuronal Death via Inhibiting Caspase-7/AIF Pathway in MPTP/p Mouse Model of Parkinson’s Disease
- (2016) Chen Qiao et al. MOLECULAR NEUROBIOLOGY
- Serum immune markers and disease progression in an incident Parkinson's disease cohort (ICICLE-PD)
- (2016) Caroline H. Williams-Gray et al. MOVEMENT DISORDERS
- Cdk5-Dependent Activation of Neuronal Inflammasomes in Parkinson's Disease
- (2016) Pei Zhang et al. MOVEMENT DISORDERS
- Origin, fate and dynamics of macrophages at central nervous system interfaces
- (2016) Tobias Goldmann et al. NATURE IMMUNOLOGY
- Permeability of blood-brain barrier in macaque model of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson disease
- (2016) Thibaud Thiollier et al. SYNAPSE
- Aberrations in Peripheral Inflammatory Cytokine Levels in Parkinson Disease
- (2016) Xiao-Yan Qin et al. JAMA Neurology
- Alpha-Synuclein in Parkinson’s Disease: From Pathogenetic Dysfunction to Potential Clinical Application
- (2016) Lingjia Xu et al. Parkinsons Disease
- Recent Advances of the NLRP3 Inflammasome in Central Nervous System Disorders
- (2016) Keren Zhou et al. Journal of Immunology Research
- Microglia-Derived Cytokines/Chemokines Are Involved in the Enhancement of LPS-Induced Loss of Nigrostriatal Dopaminergic Neurons in DJ-1 Knockout Mice
- (2016) Chia-Hung Chien et al. PLoS One
- Dopamine and T cells: dopamine receptors and potent effects on T cells, dopamine production in T cells, and abnormalities in the dopaminergic system in T cells in autoimmune, neurological and psychiatric diseases
- (2015) M. Levite Acta Physiologica
- Partial depletion of the proinflammatory monocyte population is neuroprotective in the myenteric plexus but not in the basal ganglia in a MPTP mouse model of Parkinson’s disease
- (2015) M. Côté et al. BRAIN BEHAVIOR AND IMMUNITY
- Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome
- (2015) Yiqing Yan et al. CELL
- Initiation and perpetuation of NLRP3 inflammasome activation and assembly
- (2015) Eric I. Elliott et al. IMMUNOLOGICAL REVIEWS
- Role of Inflammasomes in Intestinal Inflammation and Crohnʼs Disease
- (2015) Anthony Opipari et al. INFLAMMATORY BOWEL DISEASES
- Rotenone-induced Impairment of Mitochondrial Electron Transport Chain Confers a Selective Priming Signal for NLRP3 Inflammasome Activation
- (2015) Ji-Hee Won et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Striatal Blood–Brain Barrier Permeability in Parkinson'S Disease
- (2015) Madison T Gray et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Adaptive Immunity in Neurodegenerative and Neuropsychological Disorders
- (2015) R. Lee Mosley Journal of Neuroimmune Pharmacology
- The interleukin 1 alpha, interleukin 1 beta, interleukin 6 and alpha-2-macroglobulin serum levels in patients with early or late onset Alzheimer's disease, mild cognitive impairment or Parkinson's disease
- (2015) Erdinç Dursun et al. JOURNAL OF NEUROIMMUNOLOGY
- Control of adaptive immunity by the innate immune system
- (2015) Akiko Iwasaki et al. NATURE IMMUNOLOGY
- A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
- (2015) Rebecca C Coll et al. NATURE MEDICINE
- Deep-brain stimulation associates with improved microvascular integrity in the subthalamic nucleus in Parkinson's disease
- (2015) Ilse S. Pienaar et al. NEUROBIOLOGY OF DISEASE
- Increased CSF biomarkers of angiogenesis in Parkinson disease
- (2015) Shorena Janelidze et al. NEUROLOGY
- Saxagliptin: A novel antiparkinsonian approach
- (2015) Noha N. Nassar et al. NEUROPHARMACOLOGY
- Attenuation of microglial RANTES by NEMO-binding domain peptide inhibits the infiltration of CD8+ T cells in the nigra of hemiparkinsonian monkey
- (2015) A. Roy et al. NEUROSCIENCE
- Characterization of gastrointestinal disorders in patients with parkinsonian syndromes
- (2015) Hyeyoung Park et al. PARKINSONISM & RELATED DISORDERS
- Neuroprotective potential of ferulic acid in the rotenone model of Parkinson’s disease
- (2015) Emdadul Haque et al. Drug Design Development and Therapy
- Immunotherapy in Parkinson’s Disease: Micromanaging Alpha-Synuclein Aggregation
- (2015) Sonia George et al. Journal of Parkinsons Disease
- Inflammatory dysregulation of blood monocytes in Parkinson’s disease patients
- (2014) Veselin Grozdanov et al. ACTA NEUROPATHOLOGICA
- Role of CCR2 in Inflammatory Conditions of the Central Nervous System
- (2014) Hannah X Chu et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Cerebral microbleeds in patients with Parkinson’s disease
- (2014) Jee Hyun Ham et al. JOURNAL OF NEUROLOGY
- Detection of Microglial Activation in an Acute Model of Neuroinflammation Using PET and Radiotracers 11C-(R)-PK11195 and 18F-GE-180
- (2014) A. M. Dickens et al. JOURNAL OF NUCLEAR MEDICINE
- Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
- (2014) Elisa Gomez Perdiguero et al. NATURE
- Microglial priming in neurodegenerative disease
- (2014) V. Hugh Perry et al. Nature Reviews Neurology
- Dynamic changes in pro- and anti-inflammatory cytokines in microglia after PPAR-γ agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease
- (2014) Augusta Pisanu et al. NEUROBIOLOGY OF DISEASE
- Correlation between Serum RANTES Levels and the Severity of Parkinson’s Disease
- (2014) Peng Tang et al. Oxidative Medicine and Cellular Longevity
- Exploring LPS-induced sepsis in rats and mice as a model to study potential protective effects of the nociceptin/orphanin FQ system
- (2014) Roisin C. Thomas et al. PEPTIDES
- Abrogation of -synuclein-mediated dopaminergic neurodegeneration in LRRK2-deficient rats
- (2014) J. P. L. Daher et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Astrocytic modulation of blood brain barrier: perspectives on Parkinson’s disease
- (2014) Ricardo Cabezas et al. Frontiers in Cellular Neuroscience
- Cognitive Status Correlates with CXCL10/IP-10 Levels in Parkinson’s Disease
- (2014) Natália Pessoa Rocha et al. Parkinsons Disease
- Microglial phenotypes and toll-like receptor 2 in the substantia nigra and hippocampus of incidental Lewy body disease cases and Parkinson’s disease patients
- (2014) Karlijn J Doorn et al. Acta Neuropathologica Communications
- Distinguishing ecological from evolutionary approaches to transposable elements
- (2013) Stefan Linquist et al. BIOLOGICAL REVIEWS
- Implications of Parkinson’s Disease Pathophysiology for the Development of Cell Replacement Strategies and Drug Discovery in Neurodegenerative Diseases
- (2013) Francisco Pan-Montojo et al. CNS & Neurological Disorders-Drug Targets
- Doxycycline restrains glia and confers neuroprotection in a 6-OHDA Parkinson model
- (2013) Marcio Lazzarini et al. GLIA
- Exenatide and the treatment of patients with Parkinson’s disease
- (2013) Iciar Aviles-Olmos et al. JOURNAL OF CLINICAL INVESTIGATION
- MHCII Is Required for -Synuclein-Induced Activation of Microglia, CD4 T Cell Proliferation, and Dopaminergic Neurodegeneration
- (2013) A. S. Harms et al. JOURNAL OF NEUROSCIENCE
- Bacillus Calmette-Guerin vaccine-mediated neuroprotection is associated with regulatory T-cell induction in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
- (2013) Goran Laćan et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Origin of monocytes and macrophages in a committed progenitor
- (2013) Jan Hettinger et al. NATURE IMMUNOLOGY
- The microglial sensome revealed by direct RNA sequencing
- (2013) Suzanne E Hickman et al. NATURE NEUROSCIENCE
- Triggering of Inflammasome by Aggregated α–Synuclein, an Inflammatory Response in Synucleinopathies
- (2013) Gaia Codolo et al. PLoS One
- Leucine-Rich Repeat Kinase 2 (LRRK2)-Deficient Rats Exhibit Renal Tubule Injury and Perturbations in Metabolic and Immunological Homeostasis
- (2013) Daniel Ness et al. PLoS One
- Role of LRRK2 kinase activity in the pathogenesis of Parkinson's disease
- (2012) Elisa Greggio BIOCHEMICAL SOCIETY TRANSACTIONS
- Neuro-protective effects of bee venom by suppression of neuroinflammatory responses in a mouse model of Parkinson’s disease: Role of regulatory T cells
- (2012) Eun Sook Chung et al. BRAIN BEHAVIOR AND IMMUNITY
- Regionally-specific microglial activation in young mice over-expressing human wildtype alpha-synuclein
- (2012) Melanie B. Watson et al. EXPERIMENTAL NEUROLOGY
- CD4+ Regulatory and Effector/Memory T Cell Subsets Profile Motor Dysfunction in Parkinson’s Disease
- (2012) Jessica A. Hutter Saunders et al. Journal of Neuroimmune Pharmacology
- Increased blood-cerebrospinal fluid transfer of albumin in advanced Parkinson’s disease
- (2012) Valerio Pisani et al. Journal of Neuroinflammation
- Association between Parkinson's disease and the HLA-DRB1 locus
- (2012) Ismaïl Ahmed et al. MOVEMENT DISORDERS
- Long-term polarization of microglia upon α-synuclein overexpression in nonhuman primates
- (2012) P. Barkholt et al. NEUROSCIENCE
- In vivo microglia activation in very early dementia with Lewy bodies, comparison with Parkinson's disease
- (2012) S. Iannaccone et al. PARKINSONISM & RELATED DISORDERS
- The path from the choroid plexus to the subventricular zone: go with the flow!
- (2012) Ana Mendanha Falcão Frontiers in Cellular Neuroscience
- Erratum: IFN-γ signaling, with the synergistic contribution of TNF-α, mediates cell specific microglial and astroglial activation in experimental models of Parkinson’s disease
- (2012) C Barcia et al. Cell Death & Disease
- Impaired hepatic function and central dopaminergic denervation in a rodent model of Parkinson's disease: A self-perpetuating crosstalk?
- (2011) Mariapia Vairetti et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- An 18-kDa Translocator Protein (TSPO) Polymorphism Explains Differences in Binding Affinity of the PET Radioligand PBR28
- (2011) David R Owen et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Parkinson’s disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures
- (2011) Mansoureh Hakimi et al. JOURNAL OF NEURAL TRANSMISSION
- Evidence for angiogenesis in Parkinson’s disease, incidental Lewy body disease, and progressive supranuclear palsy
- (2011) Brinda Desai Bradaric et al. JOURNAL OF NEURAL TRANSMISSION
- Adhesion molecules as potential targets for neuroprotection in a rodent model of Parkinson's disease
- (2011) Marie-Therese Armentero et al. NEUROBIOLOGY OF DISEASE
- Use of ibuprofen and risk of Parkinson disease
- (2011) X. Gao et al. NEUROLOGY
- Evidence for More than One Parkinson's Disease-Associated Variant within the HLA Region
- (2011) Erin M. Hill-Burns et al. PLoS One
- IFN-γ signaling, with the synergistic contribution of TNF-α, mediates cell specific microglial and astroglial activation in experimental models of Parkinson's disease
- (2011) C Barcia et al. Cell Death & Disease
- Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression
- (2010) Min Shi et al. ANNALS OF NEUROLOGY
- Regulation of learning and memory by meningeal immunity: a key role for IL-4
- (2010) Noël C. Derecki et al. JOURNAL OF EXPERIMENTAL MEDICINE
- LRRK2 Is Involved in the IFN- Response and Host Response to Pathogens
- (2010) A. Gardet et al. JOURNAL OF IMMUNOLOGY
- Regulatory T Cells Attenuate Th17 Cell-Mediated Nigrostriatal Dopaminergic Neurodegeneration in a Model of Parkinson’s Disease
- (2010) Ashley D. Reynolds et al. JOURNAL OF IMMUNOLOGY
- Tickets to the brain: Role of CCR2 and CX3CR1 in myeloid cell entry in the CNS
- (2010) Marco Prinz et al. JOURNAL OF NEUROIMMUNOLOGY
- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
- Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease
- (2010) Taye H Hamza et al. NATURE GENETICS
- MPTP-Induced Neuroinflammation Increases the Expression of Pro-Inflammatory Cytokines and Their Receptors in Mouse Brain
- (2010) Dario Domenico Lofrumento et al. NEUROIMMUNOMODULATION
- Anti-inflammatory drugs and risk of Parkinson disease: A meta-analysis
- (2010) J. J. Gagne et al. NEUROLOGY
- Progression of Parkinson's Disease Pathology Is Reproduced by Intragastric Administration of Rotenone in Mice
- (2010) Francisco Pan-Montojo et al. PLoS One
- Microglia Acquire Distinct Activation Profiles Depending on the Degree of α-Synuclein Neuropathology in a rAAV Based Model of Parkinson's Disease
- (2010) Vanesa Sanchez-Guajardo et al. PLoS One
- Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice
- (2010) Noah Saederup et al. PLoS One
- Development of Monocytes, Macrophages, and Dendritic Cells
- (2010) F. Geissmann et al. SCIENCE
- Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
- (2010) F. Ginhoux et al. SCIENCE
- Time-dependent alterations of peripheral immune parameters after nigrostriatal dopamine depletion in a rat model of Parkinson’s disease
- (2009) Harald Engler et al. BRAIN BEHAVIOR AND IMMUNITY
- Elevated interleukin-1β induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine aggravating dopaminergic neurodegeneration in old male mice
- (2009) Min-juan Bian et al. BRAIN RESEARCH
- Multiplex Analysis of Cytokines in the Serum and Cerebrospinal Fluid of Patients With Alzheimer's Disease by Color-Coded Bead Technology
- (2009) Chulhee Choi et al. Journal of Clinical Neurology
- Exendin-4 protects dopaminergic neurons by inhibition of microglial activation and matrix metalloproteinase-3 expression in an animal model of Parkinson's disease
- (2009) Sehee Kim et al. JOURNAL OF ENDOCRINOLOGY
- Relationship between microglial activation and dopaminergic neuronal loss in the substantia nigra: a time course study in a 6-hydroxydopamine model of Parkinson’s disease
- (2009) Lilia Marinova-Mutafchieva et al. JOURNAL OF NEUROCHEMISTRY
- Acute and Chronic 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Administrations Elicit Similar Microglial Activation in the Substantia Nigra of Monkeys
- (2009) Marianne Vázquez-Claverie et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
- (2009) Wataru Satake et al. NATURE GENETICS
- Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention
- (2009) Malú G. Tansey et al. NEUROBIOLOGY OF DISEASE
- Progressive Dopaminergic Degeneration in the Chronic MPTPp Mouse Model of Parkinson’s Disease
- (2009) Nicoletta Schintu et al. NEUROTOXICITY RESEARCH
- CXCR4 and CXCL12 Expression is Increased in the Nigro-Striatal System of Parkinson’s Disease
- (2009) Mika Shimoji et al. NEUROTOXICITY RESEARCH
- Behavior, neurotransmitters and inflammation in three regimens of the MPTP mouse model of Parkinson's disease
- (2009) Dirk W. Luchtman et al. PHYSIOLOGY & BEHAVIOR
- Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models?
- (2009) Francesca Cicchetti et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Systemic Inflammation Induces Acute Behavioral and Cognitive Changes and Accelerates Neurodegenerative Disease
- (2008) Colm Cunningham et al. BIOLOGICAL PSYCHIATRY
- Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease
- (2008) M. C. Pott Godoy et al. BRAIN
- A Pilot Clinical Trial of Creatine and Minocycline in Early Parkinson Disease
- (2008) CLINICAL NEUROPHARMACOLOGY
- Reactive oxygen species up-regulate CD11b in microglia via nitric oxide: Implications for neurodegenerative diseases
- (2008) Avik Roy et al. FREE RADICAL BIOLOGY AND MEDICINE
- The lipopolysaccharide Parkinson’s disease animal model: mechanistic studies and drug discovery
- (2008) Garima Dutta et al. FUNDAMENTAL & CLINICAL PHARMACOLOGY
- Induction of lymphotoxin-α by interleukin-12 p40 homodimer, the so-called biologically inactive molecule, but not IL-12 p70
- (2008) Malabendu Jana et al. IMMUNOLOGY
- Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease
- (2008) Vanessa Brochard et al. JOURNAL OF CLINICAL INVESTIGATION
- Decreased blood–brain barrier P-glycoprotein function in the progression of Parkinson’s disease, PSP and MSA
- (2008) A. L. Bartels et al. JOURNAL OF NEURAL TRANSMISSION
- The effects of MPTP on the activation of microglia/astrocytes and cytokine/chemokine levels in different mice strains
- (2008) Y YASUDA et al. JOURNAL OF NEUROIMMUNOLOGY
- Neuroinflammation mediated by IL-1β increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease
- (2008) James B Koprich et al. Journal of Neuroinflammation
- Targeted Overexpression of Human α-Synuclein Triggers Microglial Activation and an Adaptive Immune Response in a Mouse Model of Parkinson Disease
- (2008) Shaji Theodore et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Parkin Deficiency Increases Vulnerability to Inflammation-Related Nigral Degeneration
- (2008) T. C. Frank-Cannon et al. JOURNAL OF NEUROSCIENCE
- The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
- (2008) Berislav V. Zlokovic NEURON
- Serum interleukin (IL-2, IL-10, IL-6, IL-4), TNFα, and INFγ concentrations are elevated in patients with atypical and idiopathic parkinsonism
- (2008) Bogdan Brodacki et al. NEUROSCIENCE LETTERS
- Nitrated α–Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons
- (2008) Eric J. Benner et al. PLoS One
- Synuclein activates microglia in a model of Parkinson's disease
- (2007) Xiaomin Su et al. NEUROBIOLOGY OF AGING
- The exploration of rotenone as a toxin for inducing Parkinson's disease in rats, for application in BBB transport and PK–PD experiments
- (2007) Paulien G.M. Ravenstijn et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
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