标题
How ERAP1 and ERAP2 Shape the Peptidomes of Disease-Associated MHC-I Proteins
作者
关键词
-
出版物
Frontiers in Immunology
Volume 9, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2018-10-30
DOI
10.3389/fimmu.2018.02463
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- ERAP1-dependent antigen cross-presentation determines efficacy of adoptive T cell therapy in mice
- (2018) Karin Schmidt et al. CANCER RESEARCH
- The association of ERAP1 and ERAP2 single nucleotide polymorphisms and their haplotypes with psoriasis vulgaris is dependent on the presence or absence of the HLA-C*06:02 allele and age at disease onset
- (2018) Andrzej Wiśniewski et al. HUMAN IMMUNOLOGY
- Allele-specific alterations in the peptidome underlie the joint association of HLA-A*29:02 and Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) with Birdshot Chorioretinopathy
- (2018) Alejandro Sanz-Bravo et al. MOLECULAR & CELLULAR PROTEOMICS
- Ranking the Contribution of Ankylosing Spondylitis-associated Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) Polymorphisms to Shaping the HLA-B*27 Peptidome
- (2018) Alejandro Sanz-Bravo et al. MOLECULAR & CELLULAR PROTEOMICS
- Molecular pathways for antigenic peptide generation by ER aminopeptidase 1
- (2018) Anastasia Mpakali et al. MOLECULAR IMMUNOLOGY
- The Peptide Repertoire of HLA-B27 may include Ligands with Lysine at P2 Anchor Position
- (2018) Shira Yair-Sabag et al. PROTEOMICS
- Gene Variation of Endoplasmic Reticulum Aminopeptidases 1 and 2, and Risk of Blood Pressure Progression and Incident Hypertension among 17,255 Initially Healthy Women
- (2018) Robert Y. L. Zee et al. International Journal of Genomics
- The role of polymorphic ERAP1 in autoinflammatory disease
- (2018) Emma Reeves et al. BIOSCIENCE REPORTS
- Functionally distinct ERAP1 and ERAP2 are a hallmark of HLA-A29-(Birdshot) Uveitis
- (2018) Jonas J W Kuiper, Jessica van Setten, Matthew Devall, Mircea Cretu-Stancu, Sanne Hiddingh, Roel A Ophoff, Tom O A R Missotten, Mirjam van Velthoven et al. HUMAN MOLECULAR GENETICS
- An allelic variant in the intergenic region between ERAP1 and ERAP2 correlates with an inverse expression of the two genes
- (2018) Fabiana Paladini et al. Scientific Reports
- Integrated Systems Biology Approach Identifies Novel Maternal and Placental Pathways of Preeclampsia
- (2018) Nandor Gabor Than et al. Frontiers in Immunology
- Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction
- (2017) Jennifer G. Abelin et al. IMMUNITY
- Mice expressing human ERAP1 variants associated with ankylosing spondylitis have altered T-cell repertoires and NK cell functions, as well as increased in utero and perinatal mortality
- (2017) David P W Rastall et al. INTERNATIONAL IMMUNOLOGY
- Separate effects of the ankylosing spondylitis associated ERAP1 and ERAP2 aminopeptidases determine the influence of their combined phenotype on the HLA-B*27 peptidome
- (2017) Adrian Martín-Esteban et al. JOURNAL OF AUTOIMMUNITY
- The molecular basis for peptide repertoire selection in the human leukocyte antigen (HLA) C*06:02 molecule
- (2017) Jesse I. Mobbs et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Behçet's disease-associated variant of the aminopeptidase ERAP1 shapes a low-affinity HLA-B*51 peptidome by differential subpeptidome processing
- (2017) Pablo Guasp et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Human Leukocyte Antigen (HLA)-B27 Peptidomein Vivo, in Spondyloarthritis-susceptible HLA-B27 Transgenic Rats and the Effect of Erap1 Deletion
- (2017) Eilon Barnea et al. MOLECULAR & CELLULAR PROTEOMICS
- Heterozygosity of the 721.221-B*51:01 Cell Line Used in the Study by Guasp et (Arthritis Rheumatol, February 2016)
- (2017) Arthritis & Rheumatology
- Genetic Variants in ERAP1 and ERAP2 Associated With Immune-Mediated Diseases Influence Protein Expression and the Isoform Profile
- (2017) Aimee L. Hanson et al. Arthritis & Rheumatology
- A single endoplasmic reticulum aminopeptidase-1 protein allotype is a strong risk factor for Behçet's disease in HLA-B*51 carriers
- (2016) Masaki Takeuchi et al. ANNALS OF THE RHEUMATIC DISEASES
- Molecular and pathogenic effects of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in MHC-I-associated inflammatory disorders: Towards a unifying view
- (2016) José A. López de Castro et al. MOLECULAR IMMUNOLOGY
- Screening Identifies Thimerosal as a Selective Inhibitor of Endoplasmic Reticulum Aminopeptidase 1
- (2016) Athanasios Stamogiannos et al. ACS Medicinal Chemistry Letters
- ERAP1-ERAP2 dimers trim MHC I-bound precursor peptides; implications for understanding peptide editing
- (2016) Hanna Chen et al. Scientific Reports
- Activation-Induced Killer Cell Immunoglobulin-like Receptor 3DL2 Binding to HLA-B27 Licenses Pathogenic T Cell Differentiation in Spondyloarthritis
- (2016) Anna Ridley et al. Arthritis & Rheumatology
- Functional Interaction of the Ankylosing Spondylitis-Associated Endoplasmic Reticulum Aminopeptidase 2 With the HLA-B*27 Peptidome in Human Cells
- (2016) Adrian Martín-Esteban et al. Arthritis & Rheumatology
- The Peptidome of Behçet's Disease-Associated HLA-B*51:01 Includes Two Subpeptidomes Differentially Shaped by Endoplasmic Reticulum Aminopeptidase 1
- (2016) Pablo Guasp et al. Arthritis & Rheumatology
- ERAP2is associated with ankylosing spondylitis inHLA-B27-positive andHLA-B27-negative patients
- (2015) Philip C Robinson et al. ANNALS OF THE RHEUMATIC DISEASES
- ERAP1 Regulates Natural Killer Cell Function by Controlling the Engagement of Inhibitory Receptors
- (2015) L. Cifaldi et al. CANCER RESEARCH
- MHC Genes Linked to Autoimmune Disease
- (2015) Philip Deitiker et al. CRITICAL REVIEWS IN IMMUNOLOGY
- Endoplasmic reticulum-associated amino-peptidase 1 and rheumatic disease
- (2015) Michael J. Ombrello et al. CURRENT OPINION IN RHEUMATOLOGY
- Association of single nucleotide polymorphisms in the 3′UTR of ERAP1 gene with essential hypertension in the Northeastern Han Chinese
- (2015) Sibao Yang et al. GENE
- Substrate-dependent nitric oxide synthesis by secreted endoplasmic reticulum aminopeptidase 1 in macrophages
- (2015) Y. Goto et al. JOURNAL OF BIOCHEMISTRY
- Structural Basis for Antigenic Peptide Recognition and Processing by Endoplasmic Reticulum (ER) Aminopeptidase 2
- (2015) Anastasia Mpakali et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autoimmune Disease-Associated Variants of Extracellular Endoplasmic Reticulum Aminopeptidase 1 Induce Altered Innate Immune Responses by Human Immune Cells
- (2015) Yasser A. Aldhamen et al. Journal of Innate Immunity
- Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) Polymorphism Relevant to Inflammatory Disease Shapes the Peptidome of the Birdshot Chorioretinopathy-Associated HLA-A*29:02 Antigen
- (2015) Carlos Alvarez-Navarro et al. MOLECULAR & CELLULAR PROTEOMICS
- ERp44 Exerts Redox-Dependent Control of Blood Pressure at the ER
- (2015) Chihiro Hisatsune et al. MOLECULAR CELL
- Effects of polymorphic variation on the mechanism of Endoplasmic Reticulum Aminopeptidase 1
- (2015) Athanasios Stamogiannos et al. MOLECULAR IMMUNOLOGY
- 'MHC-I-opathy'—unified concept for spondyloarthritis and Behçet disease
- (2015) Dennis McGonagle et al. Nature Reviews Rheumatology
- The immunopathogenesis of birdshot chorioretinopathy; a bird of many feathers
- (2015) Jonas Kuiper et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility
- (2015) Xianyong Yin et al. Nature Communications
- Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1
- (2015) Adrian Cortes et al. Nature Communications
- Evaluating the Performance of Fine-Mapping Strategies at Common Variant GWAS Loci
- (2015) Martijn van de Bunt et al. PLoS Genetics
- Dominant Role of the ERAP1 Polymorphism R528K in Shaping the HLA-B27 Peptidome Through Differential Processing Determined by Multiple Peptide Residues
- (2015) Alejandro Sanz-Bravo et al. Arthritis & Rheumatology
- ERAP1Gene Expression Is Influenced by Nonsynonymous Polymorphisms Associated With Predisposition to Spondyloarthritis
- (2015) Félicie Costantino et al. Arthritis & Rheumatology
- Revisiting the Arthritogenic Peptide Theory: Quantitative Not Qualitative Changes in the Peptide Repertoire of HLA-B27 Allotypes
- (2015) Ralf B. Schittenhelm et al. Arthritis & Rheumatology
- A genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy
- (2014) Jonas J.W. Kuiper et al. HUMAN MOLECULAR GENETICS
- TLR-Mediated Secretion of Endoplasmic Reticulum Aminopeptidase 1 from Macrophages
- (2014) Y. Goto et al. JOURNAL OF IMMUNOLOGY
- ERAP1–ERAP2 Dimerization Increases Peptide-Trimming Efficiency
- (2014) Irini Evnouchidou et al. JOURNAL OF IMMUNOLOGY
- Peptide Handling by HLA-B27 Subtypes Influences Their Biological Behavior, Association with Ankylosing Spondylitis and Susceptibility to Endoplasmic Reticulum Aminopeptidase 1 (ERAP1)
- (2014) Noel García-Medel et al. MOLECULAR & CELLULAR PROTEOMICS
- Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides
- (2014) Diana Paola Granados et al. Nature Communications
- A Role for Naturally Occurring Alleles of Endoplasmic Reticulum Aminopeptidases in Tumor Immunity and Cancer Pre-Disposition
- (2014) Efstratios Stratikos et al. Frontiers in Oncology
- Endoplasmic reticulum aminopeptidase-1 alleles associated with increased risk of ankylosing spondylitis reduce HLA-B27 mediated presentation of multiple antigens
- (2013) Sergey S. Seregin et al. AUTOIMMUNITY
- Combined Effects of Ankylosing Spondylitis-associated ERAP1 Polymorphisms Outside the Catalytic and Peptide-binding Sites on the Processing of Natural HLA-B27 Ligands
- (2013) Adrian Martín-Esteban et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Naturally Occurring ERAP1 Haplotypes Encode Functionally Distinct Alleles with Fine Substrate Specificity
- (2013) E. Reeves et al. JOURNAL OF IMMUNOLOGY
- Antigenic peptide trimming by ER aminopeptidases—Insights from structural studies
- (2013) Efstratios Stratikos et al. MOLECULAR IMMUNOLOGY
- The biochemistry and immunology of non-canonical forms of HLA-B27
- (2013) Jacqueline Shaw et al. MOLECULAR IMMUNOLOGY
- ERAP1 structure, function and pathogenetic role in ankylosing spondylitis and other MHC-associated diseases
- (2013) Carlos Alvarez-Navarro et al. MOLECULAR IMMUNOLOGY
- HLA-B27 misfolding and ankylosing spondylitis
- (2013) Robert A. Colbert et al. MOLECULAR IMMUNOLOGY
- Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1
- (2013) Yohei Kirino et al. NATURE GENETICS
- Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci
- (2013) Adrian Cortes et al. NATURE GENETICS
- Endoplasmic Reticulum Aminopeptidase-1 Functions Regulate Key Aspects of the Innate Immune Response
- (2013) Yasser A. Aldhamen et al. PLoS One
- Critical Role of Endoplasmic Reticulum Aminopeptidase 1 in Determining the Length and Sequence of Peptides Bound and Presented by HLA-B27
- (2013) Liye Chen et al. Arthritis & Rheumatology
- A novelERAP2haplotype structure in a Chilean population: implications for ERAP2 protein expression and preeclampsia risk
- (2013) Derek L. Vanhille et al. Molecular Genetics & Genomic Medicine
- Peptidases trimming MHC class I ligands
- (2012) Mirjana Weimershaus et al. CURRENT OPINION IN IMMUNOLOGY
- A Common Single Nucleotide Polymorphism in Endoplasmic Reticulum Aminopeptidase 2 Induces a Specificity Switch That Leads to Altered Antigen Processing
- (2012) I. Evnouchidou et al. JOURNAL OF IMMUNOLOGY
- Genetic Association with ERAP1 in Psoriasis Is Confined to Disease Onset after Puberty and Not Dependent on HLA-C*06
- (2012) Josefin Lysell et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Functional Interaction of the Ankylosing Spondylitis-associated Endoplasmic Reticulum Aminopeptidase 1 Polymorphism and HLA-B27in Vivo
- (2012) Noel García-Medel et al. MOLECULAR & CELLULAR PROTEOMICS
- Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
- (2012) Lam C Tsoi et al. NATURE GENETICS
- The Crystal Structure of Human Endoplasmic Reticulum Aminopeptidase 2 Reveals the Atomic Basis for Distinct Roles in Antigen Processing
- (2011) James R. Birtley et al. BIOCHEMISTRY
- Nitric oxide synthases: regulation and function
- (2011) U. Forstermann et al. EUROPEAN HEART JOURNAL
- Secretion of Endoplasmic Reticulum Aminopeptidase 1 Is Involved in the Activation of Macrophages Induced by Lipopolysaccharide and Interferon-γ
- (2011) Yoshikuni Goto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cutting Edge: Coding Single Nucleotide Polymorphisms of Endoplasmic Reticulum Aminopeptidase 1 Can Affect Antigenic Peptide Generation In Vitro by Influencing Basic Enzymatic Properties of the Enzyme
- (2011) I. Evnouchidou et al. JOURNAL OF IMMUNOLOGY
- Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility
- (2011) David M Evans et al. NATURE GENETICS
- Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1
- (2011) Tina T Nguyen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- HLA-B*51 and Behçet Disease
- (2011) Ahmet Gul et al. OCULAR IMMUNOLOGY AND INFLAMMATION
- Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming
- (2011) G. Kochan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The HLA-B2705 peptidome
- (2010) Lilach Halevi et al. ARTHRITIS AND RHEUMATISM
- A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
- (2010) Amy Strange et al. NATURE GENETICS
- Balancing Selection Maintains a Form of ERAP2 that Undergoes Nonsense-Mediated Decay and Affects Antigen Presentation
- (2010) Aida M. Andrés et al. PLoS Genetics
- HLA-B51/B5and the risk of Behçet's disease: A systematic review and meta-analysis of case-control genetic association studies
- (2009) Mathilde de Menthon et al. ARTHRITIS AND RHEUMATISM
- Investigating the genetic association between ERAP1 and ankylosing spondylitis
- (2009) David Harvey et al. HUMAN MOLECULAR GENETICS
- From HLA-B27 to spondyloarthritis: a journey through the ER
- (2009) Robert A. Colbert et al. IMMUNOLOGICAL REVIEWS
- The Specificity of Trimming of MHC Class I-Presented Peptides in the Endoplasmic Reticulum
- (2009) A. Hearn et al. JOURNAL OF IMMUNOLOGY
- Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non‐lymphoid human tissues
- (2008) Doriana Fruci et al. JOURNAL OF CELLULAR PHYSIOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started