An allelic variant in the intergenic region between ERAP1 and ERAP2 correlates with an inverse expression of the two genes

ERAP1 and HLA-C interaction in inflammatory bowel disease in the Spanish population

(2017) Patricia Castro-Santos et al.   Innate Immunity

ERAP1association with ankylosing spondylitis is attributable to common genotypes rather than rare haplotype combinations

(2017) Amity R. Roberts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Variants in ERAP1 and ERAP2 Associated With Immune-Mediated Diseases Influence Protein Expression and the Isoform Profile

(2017) Aimee L. Hanson et al.   Arthritis & Rheumatology

Associations between ERAP1 polymorphisms and susceptibility to ankylosing spondylitis: a meta-analysis

(2016) Young Ho Lee et al.   CLINICAL RHEUMATOLOGY

ERAP1 reduces accumulation of aberrant and disulfide-linked forms of HLA-B27 on the cell surface

(2016) Tri M. Tran et al.   MOLECULAR IMMUNOLOGY

Molecular and pathogenic effects of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in MHC-I-associated inflammatory disorders: Towards a unifying view

(2016) José A. López de Castro et al.   MOLECULAR IMMUNOLOGY

The Ankylosing Spondylitis-Associated HLA-B*2705 Presents a B*0702-Restricted EBV Epitope and Sustains the Clonal Amplification of Cytotoxic T Cells in Patients

(2016) Valentina Tedeschi et al.   MOLECULAR MEDICINE

Endoplasmic reticulum aminopeptidase 1 and rheumatic disease

(2015) Tri M. Tran et al.   CURRENT OPINION IN RHEUMATOLOGY

Structural Basis for Antigenic Peptide Recognition and Processing by Endoplasmic Reticulum (ER) Aminopeptidase 2

(2015) Anastasia Mpakali et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endoplasmic reticulum aminopeptidase 2 is highly expressed in papillary thyroid microcarcinoma with cervical lymph node metastasis

(2015) JaeBok Lee et al.   Journal of Cancer Research and Therapeutics

Autoimmune Disease-Associated Variants of Extracellular Endoplasmic Reticulum Aminopeptidase 1 Induce Altered Innate Immune Responses by Human Immune Cells

(2015) Yasser A. Aldhamen et al.   Journal of Innate Immunity

ERp44 Exerts Redox-Dependent Control of Blood Pressure at the ER

(2015) Chihiro Hisatsune et al.   MOLECULAR CELL

Effects of polymorphic variation on the mechanism of Endoplasmic Reticulum Aminopeptidase 1

(2015) Athanasios Stamogiannos et al.   MOLECULAR IMMUNOLOGY

'MHC-I-opathy'—unified concept for spondyloarthritis and Behçet disease

(2015) Dennis McGonagle et al.   Nature Reviews Rheumatology

ERAP1 biology and assessment in Ankylosing Spondylitis

(2015) Philip C. Robinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endoplasmic reticulum aminopeptidases in the pathogenesis of ankylosing spondylitis: Fig. 1

(2015) Tony J. Kenna et al.   RHEUMATOLOGY

ERAP1Gene Expression Is Influenced by Nonsynonymous Polymorphisms Associated With Predisposition to Spondyloarthritis

(2015) Félicie Costantino et al.   Arthritis & Rheumatology

A genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy

(2014) Jonas J.W. Kuiper et al.   HUMAN MOLECULAR GENETICS

ERAP1 in the pathogenesis of ankylosing spondylitis

(2014) Emma Reeves et al.   IMMUNOLOGIC RESEARCH

Peptide Handling by HLA-B27 Subtypes Influences Their Biological Behavior, Association with Ankylosing Spondylitis and Susceptibility to Endoplasmic Reticulum Aminopeptidase 1 (ERAP1)

(2014) Noel García-Medel et al.   MOLECULAR & CELLULAR PROTEOMICS

Functionally distinctERAP1allotype combinations distinguish individuals with Ankylosing Spondylitis

(2014) Emma Reeves et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endoplasmic reticulum aminopeptidase 1 function and its pathogenic role in regulating innate and adaptive immunity in cancer and major histocompatibility complex class I-associated autoimmune diseases

(2014) D. Fruci et al.   TISSUE ANTIGENS

A Role for Naturally Occurring Alleles of Endoplasmic Reticulum Aminopeptidases in Tumor Immunity and Cancer Pre-Disposition

(2014) Efstratios Stratikos et al.   Frontiers in Oncology

Endoplasmic reticulum aminopeptidase-1 alleles associated with increased risk of ankylosing spondylitis reduce HLA-B27 mediated presentation of multiple antigens

(2013) Sergey S. Seregin et al.   AUTOIMMUNITY

Endoplasmic reticulum aminopeptidases: biochemistry, physiology and pathology

(2013) A. Hattori et al.   JOURNAL OF BIOCHEMISTRY

Combined Effects of Ankylosing Spondylitis-associated ERAP1 Polymorphisms Outside the Catalytic and Peptide-binding Sites on the Processing of Natural HLA-B27 Ligands

(2013) Adrian Martín-Esteban et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Naturally Occurring ERAP1 Haplotypes Encode Functionally Distinct Alleles with Fine Substrate Specificity

(2013) E. Reeves et al.   JOURNAL OF IMMUNOLOGY

ERAP1 structure, function and pathogenetic role in ankylosing spondylitis and other MHC-associated diseases

(2013) Carlos Alvarez-Navarro et al.   MOLECULAR IMMUNOLOGY

Transcriptome and genome sequencing uncovers functional variation in humans

(2013) Tuuli Lappalainen et al.   NATURE

Subtype specific genetic associations for juvenile idiopathic arthritis: ERAP1 with the enthesitis related arthritis subtype and IL23R with juvenile psoriatic arthritis

(2013) Anne Hinks et al.   ARTHRITIS RESEARCH & THERAPY

The putative role of endoplasmic reticulum aminopeptidases in autoimmunity: Insights from genomic-wide association studies

(2012) Alessandra Fierabracci et al.   AUTOIMMUNITY REVIEWS

A Common Single Nucleotide Polymorphism in Endoplasmic Reticulum Aminopeptidase 2 Induces a Specificity Switch That Leads to Altered Antigen Processing

(2012) I. Evnouchidou et al.   JOURNAL OF IMMUNOLOGY

A Functional Variant in ERAP1 Predisposes to Multiple Sclerosis

(2012) Franca Rosa Guerini et al.   PLoS One

Natural Killer Cells Efficiently Reject Lymphoma Silenced for the Endoplasmic Reticulum Aminopeptidase Associated with Antigen Processing

(2011) L. Cifaldi et al.   CANCER RESEARCH

Identification of QTL genes for BMD variation using both linkage and gene-based association approaches

(2011) Gloria Hoi-Yee Li et al.   HUMAN GENETICS

Unraveling the functional implications of GWAS: how T cell protein tyrosine phosphatase drives autoimmune disease

(2011) Julie Zikherman et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: Coding Single Nucleotide Polymorphisms of Endoplasmic Reticulum Aminopeptidase 1 Can Affect Antigenic Peptide Generation In Vitro by Influencing Basic Enzymatic Properties of the Enzyme

(2011) I. Evnouchidou et al.   JOURNAL OF IMMUNOLOGY

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

(2011) David M Evans et al.   NATURE GENETICS

Distinct molecular mechanisms leading to deficient expression of ER-resident aminopeptidases in melanoma

(2010) Esther Kamphausen et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

NF- B, and not MYCN, Regulates MHC Class I and Endoplasmic Reticulum Aminopeptidases in Human Neuroblastoma Cells

(2010) M. Forloni et al.   CANCER RESEARCH

Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection

(2010) R. Cagliani et al.   HUMAN MOLECULAR GENETICS

Balancing Selection Maintains a Form of ERAP2 that Undergoes Nonsense-Mediated Decay and Affects Antigen Presentation

(2010) Aida M. Andrés et al.   PLoS Genetics

Single nucleotide polymorphisms in antigen processing machinery component ERAP1 significantly associate with clinical outcome in cervical carcinoma

(2009) Akash M. Mehta et al.   GENES CHROMOSOMES & CANCER

Investigating the genetic association between ERAP1 and ankylosing spondylitis

(2009) David Harvey et al.   HUMAN MOLECULAR GENETICS

Fine-Scale Variation and Genetic Determinants of Alternative Splicing across Individuals

(2009) Jasmin Coulombe-Huntington et al.   PLoS Genetics

Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus

(2008) E Y M G Fung et al.   GENES AND IMMUNITY

Nonsense-mediated messenger RNA decay of survival motor neuron 1 causes spinal muscular atrophy

(2008) Lars Brichta et al.   HUMAN GENETICS

Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non‐lymphoid human tissues

(2008) Doriana Fruci et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Evolutionary Signatures of Common Human Cis-Regulatory Haplotypes

(2008) Ching Ouyang et al.   PLoS One