Activation-Induced Killer Cell Immunoglobulin-like Receptor 3DL2 Binding to HLA-B27 Licenses Pathogenic T Cell Differentiation in Spondyloarthritis

The D0 Ig-like Domain Plays a Central Role in the Stronger Binding of KIR3DL2 to B27 Free H Chain Dimers

(2015) Hiroko Hatano et al.   JOURNAL OF IMMUNOLOGY

KIR3DL2 Binds to HLA-B27 Dimers and Free H Chains More Strongly than Other HLA Class I and Promotes the Expansion of T Cells in Ankylosing Spondylitis

(2013) I. Wong-Baeza et al.   JOURNAL OF IMMUNOLOGY

The arthritis-associated HLA-B*27:05 allele forms more cell surface B27 dimer and free heavy chain ligands for KIR3DL2 than HLA-B*27:09

(2013) A. Cauli et al.   RHEUMATOLOGY

Inhibiting HLA-B27 homodimer-driven immune cell inflammation in spondylarthritis

(2012) Sravan K. Payeli et al.   ARTHRITIS AND RHEUMATISM

β-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice

(2012) Merja Ruutu et al.   ARTHRITIS AND RHEUMATISM

Proinflammatory Th17 cells are expanded and induced by dendritic cells in spondylarthritis-prone HLA-B27-transgenic rats

(2011) Simon Glatigny et al.   ARTHRITIS AND RHEUMATISM

Th17 Cells Expressing KIR3DL2+ and Responsive to HLA-B27 Homodimers Are Increased in Ankylosing Spondylitis

(2011) P. Bowness et al.   JOURNAL OF IMMUNOLOGY

Activation of OX40 Augments Th17 Cytokine Expression and Antigen-Specific Uveitis

(2010) Zili Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

Low-strength T-cell activation promotes Th17 responses

(2010) H. A. Purvis et al.   BLOOD

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci

(2010) John D Reveille et al.   NATURE GENETICS

Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

(2010) K. Nistala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic cells from spondylarthritis-prone HLA-B27-transgenic rats display altered cytoskeletal dynamics, class II major histocompatibility complex expression, and viability

(2009) Maarten Dhaenens et al.   ARTHRITIS AND RHEUMATISM

Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides

(2008) Camilla Jandus et al.   ARTHRITIS AND RHEUMATISM

Two opposite signaling outputs are driven by the KIR2DL1 receptor in human CD4+ T cells

(2008) E. Fourmentraux-Neves et al.   BLOOD