'MHC-I-opathy'—unified concept for spondyloarthritis and Behçet disease

ERAP2is associated with ankylosing spondylitis inHLA-B27-positive andHLA-B27-negative patients

(2015) Philip C Robinson et al.   ANNALS OF THE RHEUMATIC DISEASES

Endoplasmic reticulum-associated amino-peptidase 1 and rheumatic disease

(2015) Michael J. Ombrello et al.   CURRENT OPINION IN RHEUMATOLOGY

Endoplasmic reticulum aminopeptidase 1 and rheumatic disease

(2015) Tri M. Tran et al.   CURRENT OPINION IN RHEUMATOLOGY

Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) Polymorphism Relevant to Inflammatory Disease Shapes the Peptidome of the Birdshot Chorioretinopathy-Associated HLA-A*29:02 Antigen

(2015) Carlos Alvarez-Navarro et al.   MOLECULAR & CELLULAR PROTEOMICS

High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

(2015) Philippe Goyette et al.   NATURE GENETICS

A Phase 2 Trial of Guselkumab versus Adalimumab for Plaque Psoriasis

(2015) Kenneth B. Gordon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1

(2015) Adrian Cortes et al.   Nature Communications

ERAP1Gene Expression Is Influenced by Nonsynonymous Polymorphisms Associated With Predisposition to Spondyloarthritis

(2015) Félicie Costantino et al.   Arthritis & Rheumatology

Fine Mapping Major Histocompatibility Complex Associations in Psoriasis and Its Clinical Subtypes

(2014) Yukinori Okada et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Birdshot chorioretinopathy

(2014) Emily H. Shao et al.   CURRENT OPINION IN OPHTHALMOLOGY

A genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy

(2014) Jonas J.W. Kuiper et al.   HUMAN MOLECULAR GENETICS

HLA-B*51 the primary risk in Behcet disease

(2014) G. R. Wallace   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Behcet disease-associated MHC class I residues implicate antigen binding and regulation of cell-mediated cytotoxicity

(2014) M. J. Ombrello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functionally distinctERAP1allotype combinations distinguish individuals with Ankylosing Spondylitis

(2014) Emma Reeves et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vascular involvement in Behçet’s syndrome: a retrospective analysis of associations and the time course

(2014) Koray Tascilar et al.   RHEUMATOLOGY

Interleukin-17+CD8+ T Cells Are Enriched in the Joints of Patients With Psoriatic Arthritis and Correlate With Disease Activity and Joint Damage Progression

(2014) Bina Menon et al.   Arthritis & Rheumatology

Identification of Multiple Genetic Susceptibility Loci in Takayasu Arteritis

(2013) Güher Saruhan-Direskeneli et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Spondyloarthritis: may the force be with you?

(2013) Dennis McGonagle et al.   ANNALS OF THE RHEUMATIC DISEASES

Proof of concept: enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells

(2013) Peggy Jacques et al.   ANNALS OF THE RHEUMATIC DISEASES

Brief Report: Magnetic Resonance Imaging Assessment of Axial Psoriatic Arthritis: Extent of Disease Relates to HLA-B27

(2013) Concepción Castillo-Gallego et al.   ARTHRITIS AND RHEUMATISM

Endoplasmic reticulum aminopeptidase-1 alleles associated with increased risk of ankylosing spondylitis reduce HLA-B27 mediated presentation of multiple antigens

(2013) Sergey S. Seregin et al.   AUTOIMMUNITY

Severe pan-uveitis in a patient treated with vemurafenib for metastatic melanoma

(2013) Sanne EJ Wolf et al.   BMC CANCER

Pharmacogenetics of psoriasis:HLA-Cw6but notLCE3B/3Cdeletion norTNFAIP3polymorphism predisposes to clinical response to interleukin 12/23 blocker ustekinumab

(2013) M. Talamonti et al.   BRITISH JOURNAL OF DERMATOLOGY

Naturally Occurring ERAP1 Haplotypes Encode Functionally Distinct Alleles with Fine Substrate Specificity

(2013) E. Reeves et al.   JOURNAL OF IMMUNOLOGY

Genetics of ankylosing spondylitis

(2013) Philip C. Robinson et al.   MOLECULAR IMMUNOLOGY

Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1

(2013) Yohei Kirino et al.   NATURE GENETICS

Identification of multiple independent susceptibility loci in the HLA region in Behçet's disease

(2013) Travis Hughes et al.   NATURE GENETICS

Takayasu's arteritis is associated with HLA-B*52, but not with HLA-B*51, in Turkey

(2013) Ziver Sahin et al.   ARTHRITIS RESEARCH & THERAPY

Critical Role of Endoplasmic Reticulum Aminopeptidase 1 in Determining the Length and Sequence of Peptides Bound and Presented by HLA-B27

(2013) Liye Chen et al.   Arthritis & Rheumatology

Ultrasonographic Assessment of Nail in Psoriatic Disease Shows a Link between Onychopathy and Distal Interphalangeal Joint Extensor Tendon Enthesopathy

(2012) Sibel Zehra Aydin et al.   DERMATOLOGY

IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4−CD8− entheseal resident T cells

(2012) Jonathan P Sherlock et al.   NATURE MEDICINE

Relationships of HLA-B51 or B5 genotype with Behçet's disease clinical characteristics: systematic review and meta-analyses of observational studies

(2012) Carla Maldini et al.   RHEUMATOLOGY

Psoriasis patients with nail disease have a greater magnitude of underlying systemic subclinical enthesopathy than those with normal nails

(2011) Zoe R Ash et al.   ANNALS OF THE RHEUMATIC DISEASES

Salivary levels of antimicrobial peptides Hnp 1-3, Ll-37 and S100 in Behcet's disease

(2011) Gonca Mumcu et al.   ARCHIVES OF ORAL BIOLOGY

HLA associations reveal genetic heterogeneity in psoriatic arthritis and in the psoriasis phenotype

(2011) Robert Winchester et al.   ARTHRITIS AND RHEUMATISM

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

(2011) David M Evans et al.   NATURE GENETICS

HLA-B*51 and Behçet Disease

(2011) Ahmet Gul et al.   OCULAR IMMUNOLOGY AND INFLAMMATION

Ultrasound discloses entheseal involvement in inactive and low active inflammatory bowel disease without clinical signs and symptoms of spondyloarthropathy

(2011) F. Bandinelli et al.   RHEUMATOLOGY

Validation of ultrasound imaging for Achilles entheseal fibrocartilage in bovines and description of changes in humans with spondyloarthritis

(2010) S. Z. Aydin et al.   ANNALS OF THE RHEUMATIC DISEASES

Combination antibiotics as a treatment for chronic Chlamydia-induced reactive arthritis: A double-blind, placebo-controlled, prospective trial

(2010) J. D. Carter et al.   ARTHRITIS AND RHEUMATISM

Immunohistology of skin pathergy reaction in Behçet's disease

(2010) A. GÜL et al.   BRITISH JOURNAL OF DERMATOLOGY

Autoinflammatory Disease Reloaded: A Clinical Perspective

(2010) Daniel L. Kastner et al.   CELL

Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci

(2010) Nobuhisa Mizuki et al.   NATURE GENETICS

Genome-wide association study identifies variants in the MHC class I, IL10 and IL23R-IL12RB2 regions associated with Behçet's disease

(2010) Elaine F Remmers et al.   NATURE GENETICS

Azathioprine in severe uveitis of Behçet's disease

(2010) D. Saadoun et al.   ARTHRITIS CARE & RESEARCH

Predicting Important Residues and Interaction Pathways in Proteins Using Gaussian Network Model: Binding and Stability of HLA Proteins

(2010) Turkan Haliloglu et al.   PLoS Computational Biology

Genetics of Behcet disease inside and outside the MHC

(2009) A. Meguro et al.   ANNALS OF THE RHEUMATIC DISEASES

The early disease stage in axial spondylarthritis: Results from the german spondyloarthritis inception cohort

(2009) Martin Rudwaleit et al.   ARTHRITIS AND RHEUMATISM

Enthesis inflammation in recurrent acute anterior uveitis without spondylarthritis

(2009) Santiago Muñoz-Fernández et al.   ARTHRITIS AND RHEUMATISM

HLA-B51/B5and the risk of Behçet's disease: A systematic review and meta-analysis of case-control genetic association studies

(2009) Mathilde de Menthon et al.   ARTHRITIS AND RHEUMATISM

Incidence and clinical predictors of psoriatic arthritis in patients with psoriasis: A population-based study

(2009) Floranne C. Wilson et al.   ARTHRITIS AND RHEUMATISM

The pathogenesis of psoriatic arthritis and associated nail disease: not autoimmune after all?

(2009) Dennis McGonagle et al.   CURRENT OPINION IN RHEUMATOLOGY

γδ T Cells and the Lymphoid Stress-Surveillance Response

(2009) Adrian C. Hayday   IMMUNITY

Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting proteins to distinct subcellular compartments reveals unique requirements for MHC class I and II presentation

(2009) R. Belizaire et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Baseline and 1-year magnetic resonance imaging of the sacroiliac joint and lumbar spine in very early inflammatory back pain. Relationship between symptoms, HLA-B27 and disease extent and persistence

(2008) H Marzo-Ortega et al.   ANNALS OF THE RHEUMATIC DISEASES

Retinal S-antigen Th1 cell epitope mapping in patients with Behcet’s disease

(2008) Changlin Zhao et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

(2008) Andre Franke et al.   NATURE GENETICS

The Importance of Mechnikovs Thorn for an Improved Understanding of 21st Century Medicine and Immunology: A View from the Eye

(2008) D. McGonagle et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY