The Behçet's disease-associated variant of the aminopeptidase ERAP1 shapes a low-affinity HLA-B*51 peptidome by differential subpeptidome processing

Heterozygosity of the 721.221-B*51:01 Cell Line Used in the Study by Guasp et (Arthritis Rheumatol, February 2016)

(2017)   Arthritis & Rheumatology

A single endoplasmic reticulum aminopeptidase-1 protein allotype is a strong risk factor for Behçet's disease in HLA-B*51 carriers

(2016) Masaki Takeuchi et al.   ANNALS OF THE RHEUMATIC DISEASES

Molecular and pathogenic effects of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in MHC-I-associated inflammatory disorders: Towards a unifying view

(2016) José A. López de Castro et al.   MOLECULAR IMMUNOLOGY

Functional Interaction of the Ankylosing Spondylitis-Associated Endoplasmic Reticulum Aminopeptidase 2 With the HLA-B*27 Peptidome in Human Cells

(2016) Adrian Martín-Esteban et al.   Arthritis & Rheumatology

The Peptidome of Behçet's Disease-Associated HLA-B*51:01 Includes Two Subpeptidomes Differentially Shaped by Endoplasmic Reticulum Aminopeptidase 1

(2016) Pablo Guasp et al.   Arthritis & Rheumatology

ERAP1 Regulates Natural Killer Cell Function by Controlling the Engagement of Inhibitory Receptors

(2015) L. Cifaldi et al.   CANCER RESEARCH

Endoplasmic reticulum-associated amino-peptidase 1 and rheumatic disease

(2015) Michael J. Ombrello et al.   CURRENT OPINION IN RHEUMATOLOGY

Effects of polymorphic variation on the mechanism of Endoplasmic Reticulum Aminopeptidase 1

(2015) Athanasios Stamogiannos et al.   MOLECULAR IMMUNOLOGY

Uncovering the Peptide-Binding Specificities of HLA-C: A General Strategy To Determine the Specificity of Any MHC Class I Molecule

(2014) Michael Rasmussen et al.   JOURNAL OF IMMUNOLOGY

Combined Effects of Ankylosing Spondylitis-associated ERAP1 Polymorphisms Outside the Catalytic and Peptide-binding Sites on the Processing of Natural HLA-B27 Ligands

(2013) Adrian Martín-Esteban et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Naturally Occurring ERAP1 Haplotypes Encode Functionally Distinct Alleles with Fine Substrate Specificity

(2013) E. Reeves et al.   JOURNAL OF IMMUNOLOGY

Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1

(2013) Yohei Kirino et al.   NATURE GENETICS

Functional Interaction of the Ankylosing Spondylitis-associated Endoplasmic Reticulum Aminopeptidase 1 Polymorphism and HLA-B27in Vivo

(2012) Noel García-Medel et al.   MOLECULAR & CELLULAR PROTEOMICS

NetMHCcons: a consensus method for the major histocompatibility complex class I predictions

(2011) Edita Karosiene et al.   IMMUNOGENETICS

Cutting Edge: Coding Single Nucleotide Polymorphisms of Endoplasmic Reticulum Aminopeptidase 1 Can Affect Antigenic Peptide Generation In Vitro by Influencing Basic Enzymatic Properties of the Enzyme

(2011) I. Evnouchidou et al.   JOURNAL OF IMMUNOLOGY

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

(2011) David M Evans et al.   NATURE GENETICS

Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming

(2011) G. Kochan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural killer cells control a T-helper 1 response in patients with Behçet's disease

(2010) Yukie Yamaguchi et al.   ARTHRITIS RESEARCH & THERAPY

Balancing Selection Maintains a Form of ERAP2 that Undergoes Nonsense-Mediated Decay and Affects Antigen Presentation

(2010) Aida M. Andrés et al.   PLoS Genetics

HLA-B51/B5and the risk of Behçet's disease: A systematic review and meta-analysis of case-control genetic association studies

(2009) Mathilde de Menthon et al.   ARTHRITIS AND RHEUMATISM

The Specificity of Trimming of MHC Class I-Presented Peptides in the Endoplasmic Reticulum

(2009) A. Hearn et al.   JOURNAL OF IMMUNOLOGY

Essential differences in ligand presentation and T cell epitope recognition among HLA molecules of the HLA-B44 supertype

(2008) Nina Hillen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY