Stressing out the mitochondria: Mechanistic insights into NLRP3 inflammasome activation
出版年份 2018 全文链接
标题
Stressing out the mitochondria: Mechanistic insights into NLRP3 inflammasome activation
作者
关键词
-
出版物
JOURNAL OF LEUKOCYTE BIOLOGY
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2018-12-27
DOI
10.1002/jlb.mr0318-124r
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- TXNIP Deficiency Exacerbates Endotoxic Shock via the Induction of Excessive Nitric Oxide Synthesis
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- Cellular localization of NLRP3 inflammasome
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- TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria
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- Inhibitor of Apoptosis Proteins Limit RIP3 Kinase-Dependent Interleukin-1 Activation
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- Cell Volume Regulation Modulates NLRP3 Inflammasome Activation
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- The NLRP12 Inflammasome Recognizes Yersinia pestis
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- An NLRP7-Containing Inflammasome Mediates Recognition of Microbial Lipopeptides in Human Macrophages
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- Inflammasome Activators Induce Interleukin-1α Secretion via Distinct Pathways with Differential Requirement for the Protease Function of Caspase-1
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- Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
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- Caspase-8 Blocks Kinase RIPK3-Mediated Activation of the NLRP3 Inflammasome
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- Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction
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- Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation
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- Palmitate and Lipopolysaccharide Trigger Synergistic Ceramide Production in Primary Macrophages
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- Toll or Interleukin-1 Receptor (TIR) Domain-containing Adaptor Inducing Interferon-β (TRIF)-mediated Caspase-11 Protease Production Integrates Toll-like Receptor 4 (TLR4) Protein- and Nlrp3 Inflammasome-mediated Host Defense against Enteropathogens
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- TLR Agonists Stimulate Nlrp3-Dependent IL-1 Production Independently of the Purinergic P2X7 Receptor in Dendritic Cells and In Vivo
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- NLRP1-Dependent Pyroptosis Leads to Acute Lung Injury and Morbidity in Mice
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- Cutting Edge: FAS (CD95) Mediates Noncanonical IL-1 and IL-18 Maturation via Caspase-8 in an RIP3-Independent Manner
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- Deubiquitination of NLRP3 by BRCC3 Critically Regulates Inflammasome Activity
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- Dietary saturated fatty acids prime the NLRP3 inflammasome via TLR4 in dendritic cells-implications for diet-induced insulin resistance
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- NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
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- The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP
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- Anthrax Lethal Factor Cleaves Mouse Nlrp1b in Both Toxin-Sensitive and Toxin-Resistant Macrophages
- (2012) Kristina A. Hellmich et al. PLoS One
- High Fat Diet-Induced Gut Microbiota Exacerbates Inflammation and Obesity in Mice via the TLR4 Signaling Pathway
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- Critical role for calcium mobilization in activation of the NLRP3 inflammasome
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- Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors
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- The NLRP3 Inflammasome Promotes Age-Related Thymic Demise and Immunosenescence
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- Encephalomyocarditis Virus Viroporin 2B Activates NLRP3 Inflammasome
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- Anthrax Lethal Factor Cleavage of Nlrp1 Is Required for Activation of the Inflammasome
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- NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis
- (2011) Eran Elinav et al. CELL
- IFI16 Acts as a Nuclear Pathogen Sensor to Induce the Inflammasome in Response to Kaposi Sarcoma-Associated Herpesvirus Infection
- (2011) Nagaraj Kerur et al. Cell Host & Microbe
- The NLRP3 inflammasome in health and disease: the good, the bad and the ugly
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- Hyperglycemia Activates Caspase-1 and TXNIP-Mediated IL-1 Transcription in Human Adipose Tissue
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- Elimination of the NLRP3-ASC Inflammasome Protects against Chronic Obesity-Induced Pancreatic Damage
- (2011) Yun-Hee Youm et al. ENDOCRINOLOGY
- Caspase-1 Promiscuity Is Counterbalanced by Rapid Inactivation of Processed Enzyme
- (2011) John G. Walsh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation
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- Pannexin-1 Is Required for ATP Release during Apoptosis but Not for Inflammasome Activation
- (2011) Y. Qu et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome
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- The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
- (2011) Yue Zhao et al. NATURE
- Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
- (2011) Eric M. Kofoed et al. NATURE
- Non-canonical inflammasome activation targets caspase-11
- (2011) Nobuhiko Kayagaki et al. NATURE
- Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling
- (2011) Haitao Wen et al. NATURE IMMUNOLOGY
- The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
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- Inflammasome is a central player in the induction of obesity and insulin resistance
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- Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress
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- Human NLRP3 inflammasome activation is Nox1-4 independent
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- Differential Requirement for Caspase-1 Autoproteolysis in Pathogen-Induced Cell Death and Cytokine Processing
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- Deletion of the -Arrestin Protein Txnip in Mice Promotes Adiposity and Adipogenesis While Preserving Insulin Sensitivity
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- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
- NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
- (2010) Peter Duewell et al. NATURE
- The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
- (2010) Vijay A K Rathinam et al. NATURE IMMUNOLOGY
- Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
- (2010) Kiichi Nakahira et al. NATURE IMMUNOLOGY
- Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes
- (2010) Seth L Masters et al. NATURE IMMUNOLOGY
- Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1 and IL-1
- (2010) A. S. Yazdi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lack of TXNIP Protects Against Mitochondria-Mediated Apoptosis but Not Against Fatty Acid-Induced ER Stress-Mediated -Cell Death
- (2009) J. Chen et al. DIABETES
- Inflammasome-Mediated Disease Animal Models Reveal Roles for Innate but Not Adaptive Immunity
- (2009) Susannah D. Brydges et al. IMMUNITY
- Role of mitochondrial dynamics proteins in the pathophysiology of obesity and type 2 diabetes
- (2009) Antonio Zorzano et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
- (2009) Mohamed Lamkanfi et al. JOURNAL OF CELL BIOLOGY
- Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
- (2009) F. G. Bauernfeind et al. JOURNAL OF IMMUNOLOGY
- Activation of Inflammasomes Requires Intracellular Redistribution of the Apoptotic Speck-Like Protein Containing a Caspase Recruitment Domain
- (2009) N. B. Bryan et al. JOURNAL OF IMMUNOLOGY
- AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
- (2009) Teresa Fernandes-Alnemri et al. NATURE
- AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
- (2009) Veit Hornung et al. NATURE
- Thioredoxin-interacting protein links oxidative stress to inflammasome activation
- (2009) Rongbin Zhou et al. NATURE IMMUNOLOGY
- Use of Canakinumab in the Cryopyrin-Associated Periodic Syndrome
- (2009) Helen J. Lachmann et al. NEW ENGLAND JOURNAL OF MEDICINE
- Malarial Hemozoin Is a Nalp3 Inflammasome Activating Danger Signal
- (2009) Catherine Dostert et al. PLoS One
- TNF-α Induces Two Distinct Caspase-8 Activation Pathways
- (2008) Lai Wang et al. CELL
- Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes
- (2008) Junqin Chen et al. FASEB JOURNAL
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
- Stimulation of Toll-like receptor 3 and 4 induces interleukin-1β maturation by caspase-8
- (2008) Jonathan Maelfait et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
- (2008) Tatsuya Saitoh et al. NATURE
- Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
- (2008) Veit Hornung et al. NATURE IMMUNOLOGY
- The NALP3 inflammasome is involved in the innate immune response to amyloid-β
- (2008) Annett Halle et al. NATURE IMMUNOLOGY
- Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica
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