Omega-3 Free Fatty Acids Suppress Macrophage Inflammasome Activation by Inhibiting NF-κB Activation and Enhancing Autophagy

Free Fatty Acids-Sensing G Protein-Coupled Receptors in Drug Targeting and Therapeutics

(2013) Tomo Yonezawa et al.   CURRENT MEDICINAL CHEMISTRY

Omega-3 Fatty Acids Prevent Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome Activation

(2013) Yiqing Yan et al.   IMMUNITY

mTOR-Controlled Autophagy Requires Intracellular Ca2+ Signaling

(2013) Jean-Paul Decuypere et al.   PLoS One

The Omega-3 Polyunsaturated Fatty Acid DHA Induces Simultaneous Apoptosis and Autophagy via Mitochondrial ROS-Mediated Akt-mTOR Signaling in Prostate Cancer Cells Expressing Mutant p53

(2013) Soyeon Shin et al.   Biomed Research International

Omega-3 supplementation lowers inflammation in healthy middle-aged and older adults: A randomized controlled trial

(2012) Janice K. Kiecolt-Glaser et al.   BRAIN BEHAVIOR AND IMMUNITY

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

(2012) Chong-Shan Shi et al.   NATURE IMMUNOLOGY

Inflammasome Activation of IL-1 Family Mediators in Response to Cutaneous Photodamage†

(2012) Tahseen H. Nasti et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Docosahexaenoic acid induces autophagy through p53/AMPK/mTOR signaling and promotes apoptosis in human cancer cells harboring wild-type p53

(2011) Kaipeng Jing et al.   Autophagy

Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells

(2011) Timea Csak et al.   HEPATOLOGY

Free Fatty Acid Receptors FFAR1 and GPR120 as Novel Therapeutic Targets for Metabolic Disorders

(2011) Takafumi Hara et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

(2011) Haitao Wen et al.   NATURE IMMUNOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects

(2010) Da Young Oh et al.   CELL

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo

(2009) M. Mortensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP-induced autophagy is associated with rapid killing of intracellular mycobacteria within human monocytes/macrophages

(2008) Debasis Biswas et al.   BMC IMMUNOLOGY