标题
Endocrine Crosstalk Between Skeletal Muscle and the Brain
作者
关键词
-
出版物
Frontiers in Neurology
Volume 9, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2018-08-24
DOI
10.3389/fneur.2018.00698
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Effect of aerobic exercise on hippocampal volume in humans: A systematic review and meta-analysis
- (2018) Joseph Firth et al. NEUROIMAGE
- Neurturin is a PGC-1α1-controlled myokine that promotes motor neuron recruitment and neuromuscular junction formation
- (2018) Richard Mills et al. Molecular Metabolism
- Dynamic proteome profiling of individual proteins in human skeletal muscle after a high-fat diet and resistance exercise
- (2017) Donny M. Camera et al. FASEB JOURNAL
- Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults
- (2017) Leandra Abarca-Gómez et al. LANCET
- MC4R-dependent suppression of appetite by bone-derived lipocalin 2
- (2017) Ioanna Mosialou et al. NATURE
- Physiology and role of irisin in glucose homeostasis
- (2017) Nikolaos Perakakis et al. Nature Reviews Endocrinology
- Contribution of neuroinflammation and immunity to brain aging and the mitigating effects of physical and cognitive interventions
- (2017) Svetlana Di Benedetto et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Astrocytic glycogen-derived lactate fuels the brain during exhaustive exercise to maintain endurance capacity
- (2017) Takashi Matsui et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lipidomics reveals diurnal lipid oscillations in human skeletal muscle persisting in cellular myotubes cultured in vitro
- (2017) Ursula Loizides-Mangold et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1
- (2017) Cecilie Morland et al. Nature Communications
- Paracrine cross-talk between skeletal muscle and macrophages in exercise by PGC-1α-controlled BNP
- (2017) Regula Furrer et al. Scientific Reports
- Role of Nuclear Receptors in Exercise-Induced Muscle Adaptations
- (2017) Barbara Kupr et al. Cold Spring Harbor Perspectives in Medicine
- Bmal1 function in skeletal muscle regulates sleep
- (2017) J Christopher Ehlen et al. eLife
- The Role of Circadian Rhythms in Muscular and Osseous Physiology and Their Regulation by Nutrition and Exercise
- (2017) Shinya Aoyama et al. Frontiers in Neuroscience
- Increases in Brain 1H-MR Glutamine and Glutamate Signals Following Acute Exhaustive Endurance Exercise in the Rat
- (2017) Maciej Świątkiewicz et al. Frontiers in Physiology
- Global mRNA sequencing of human skeletal muscle: Search for novel exercise-regulated myokines
- (2017) S. Pourteymour et al. Molecular Metabolism
- Transcriptomic and epigenetic responses to short-term nutrient-exercise stress in humans
- (2017) R. C. Laker et al. Scientific Reports
- Endurance exercise increases skeletal muscle kynurenine aminotransferases and plasma kynurenic acid in humans
- (2016) Maja Schlittler et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Aerobic exercise augments muscle transcriptome profile of resistance exercise
- (2016) Tommy R. Lundberg et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Endocrine Effects of Circadian Disruption
- (2016) Tracy A. Bedrosian et al. Annual Review of Physiology
- Understanding the Physiology of FGF21
- (2016) Ffolliott Martin Fisher et al. Annual Review of Physiology
- Can physical exercise in old age improve memory and hippocampal function?
- (2016) Emrah Duzel et al. BRAIN
- Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function
- (2016) Hyo Youl Moon et al. Cell Metabolism
- Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise
- (2016) Paula Mera et al. Cell Metabolism
- In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons
- (2016) Philipp Mächler et al. Cell Metabolism
- Fasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy Lifespan
- (2016) Valter D. Longo et al. Cell Metabolism
- Skeletal muscle PGC-1α modulates systemic ketone body homeostasis and ameliorates diabetic hyperketonemia in mice
- (2016) Kristoffer Svensson et al. FASEB JOURNAL
- FGF21 improves cognition by restored synaptic plasticity, dendritic spine density, brain mitochondrial function and cell apoptosis in obese-insulin resistant male rats
- (2016) Piangkwan Sa-nguanmoo et al. HORMONES AND BEHAVIOR
- Brain-derived Neurotrophic Factor in Megakaryocytes
- (2016) Pedro Chacón-Fernández et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The economic burden of physical inactivity: a global analysis of major non-communicable diseases
- (2016) Ding Ding et al. LANCET
- Does physical activity attenuate, or even eliminate, the detrimental association of sitting time with mortality? A harmonised meta-analysis of data from more than 1 million men and women
- (2016) Ulf Ekelund et al. LANCET
- The ever-expanding myokinome: discovery challenges and therapeutic implications
- (2016) Martin Whitham et al. NATURE REVIEWS DRUG DISCOVERY
- Exercise-stimulated glucose uptake — regulation and implications for glycaemic control
- (2016) Lykke Sylow et al. Nature Reviews Endocrinology
- A systematic review of MRI studies examining the relationship between physical fitness and activity and the white matter of the ageing brain
- (2016) Claire E. Sexton et al. NEUROIMAGE
- Caloric restriction and exercise “mimetics’’: Ready for prime time?
- (2016) Christoph Handschin PHARMACOLOGICAL RESEARCH
- Circadian time signatures of fitness and disease
- (2016) Joseph Bass et al. SCIENCE
- Liver-derived ketone bodies are necessary for food anticipation
- (2016) Rohit Chavan et al. Nature Communications
- Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate
- (2016) Sama F Sleiman et al. eLife
- Muscle-specific loss of Bmal1 leads to disrupted tissue glucose metabolism and systemic glucose homeostasis
- (2016) Brianna D. Harfmann et al. Skeletal Muscle
- Physical Activity and Cognitive Vitality
- (2015) Ruchika Shaurya Prakash et al. Annual Review of Psychology
- Skeletal muscle as an endocrine organ: PGC-1α, myokines and exercise
- (2015) Svenia Schnyder et al. BONE
- Bone and muscle: Interactions beyond mechanical
- (2015) Marco Brotto et al. BONE
- Central and Peripheral Irisin Differentially Regulate Blood Pressure
- (2015) Weizhen Zhang et al. CARDIOVASCULAR DRUGS AND THERAPY
- Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry
- (2015) Mark P. Jedrychowski et al. Cell Metabolism
- Perilipin 5–Driven Lipid Droplet Accumulation in Skeletal Muscle Stimulates the Expression of Fibroblast Growth Factor 21
- (2015) Lydia-Ann L.S. Harris et al. DIABETES
- The search for exercise factors in humans
- (2015) Milène Catoire et al. FASEB JOURNAL
- Kynurenine pathway dysfunction in the pathophysiology and treatment of depression: Evidences from animal and human studies
- (2015) Gislaine Z. Réus et al. JOURNAL OF PSYCHIATRIC RESEARCH
- Aging and the Muscle-Bone Relationship
- (2015) Susan A. Novotny et al. PHYSIOLOGY
- Exercise as medicine - evidence for prescribing exercise as therapy in 26 different chronic diseases
- (2015) B. K. Pedersen et al. SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
- Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21
- (2015) Maitea Guridi et al. Science Signaling
- Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21
- (2015) Maitea Guridi et al. Science Signaling
- Complex Coordination of Cell Plasticity by a PGC-1α-controlled Transcriptional Network in Skeletal Muscle
- (2015) Barbara Kupr et al. Frontiers in Physiology
- Human skeletal myotubes display a cell-autonomous circadian clock implicated in basal myokine secretion
- (2015) Laurent Perrin et al. Molecular Metabolism
- Interleukin-6 contributes to early fasting-induced free fatty acid mobilization in mice
- (2014) Stephan Wueest et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- The Exercise is Medicine Global Health Initiative: a 2014 update
- (2014) Felipe Lobelo et al. BRITISH JOURNAL OF SPORTS MEDICINE
- Integrative Biology of Exercise
- (2014) John A. Hawley et al. CELL
- Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression
- (2014) Leandro Z. Agudelo et al. CELL
- FGF21 Acts Centrally to Induce Sympathetic Nerve Activity, Energy Expenditure, and Weight Loss
- (2014) Bryn M. Owen et al. Cell Metabolism
- Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans
- (2014) Paul Lee et al. Cell Metabolism
- β-Aminoisobutyric Acid Induces Browning of White Fat and Hepatic β-Oxidation and Is Inversely Correlated with Cardiometabolic Risk Factors
- (2014) Lee D. Roberts et al. Cell Metabolism
- PGC-1α Induces SPP1 to Activate Macrophages and Orchestrate Functional Angiogenesis in Skeletal Muscle
- (2014) Glenn C. Rowe et al. CIRCULATION RESEARCH
- The coactivator PGC-1α regulates skeletal muscle oxidative metabolism independently of the nuclear receptor PPARβ/δ in sedentary mice fed a regular chow diet
- (2014) Joaquín Pérez-Schindler et al. DIABETOLOGIA
- Cell-matrix interactions: focus on proteoglycan-proteinase interplay and pharmacological targeting in cancer
- (2014) Achilleas D. Theocharis et al. FEBS Journal
- Acute exercise increases brain region-specific expression of MCT1, MCT2, MCT4, GLUT1, and COX IV proteins
- (2014) Masaki Takimoto et al. JOURNAL OF APPLIED PHYSIOLOGY
- Lactate Transport and Signaling in the Brain: Potential Therapeutic Targets and Roles in Body—Brain Interaction
- (2014) Linda Hildegard Bergersen JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- AMPK agonist AICAR improves cognition and motor coordination in young and aged mice
- (2014) T. Kobilo et al. LEARNING & MEMORY
- Capillary pericytes regulate cerebral blood flow in health and disease
- (2014) Catherine N. Hall et al. NATURE
- Identification of human exercise-induced myokines using secretome analysis
- (2014) Milène Catoire et al. PHYSIOLOGICAL GENOMICS
- Physical exercise-induced hippocampal neurogenesis and antidepressant effects are mediated by the adipocyte hormone adiponectin
- (2014) S. Y. Yau et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cathepsin B: Multiple roles in cancer
- (2014) Neha Aggarwal et al. Proteomics Clinical Applications
- Brain-derived neurotrophic factor: a bridge between inflammation and neuroplasticity
- (2014) Francesca Calabrese et al. Frontiers in Cellular Neuroscience
- Neuroprotective effects of physical activity on the brain: a closer look at trophic factor signaling
- (2014) Cristy Phillips et al. Frontiers in Cellular Neuroscience
- Morphological and functional remodelling of the neuromuscular junction by skeletal muscle PGC-1α
- (2014) Anne-Sophie Arnold et al. Nature Communications
- Cytokine response of primary human myotubes in an in vitro exercise model
- (2013) Mika Scheler et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Skeletal muscle mitochondrial uncoupling drives endocrine cross-talk through the induction of FGF21 as a myokine
- (2013) Susanne Keipert et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway
- (2013) Christiane D. Wrann et al. Cell Metabolism
- Exercise Metabolism and the Molecular Regulation of Skeletal Muscle Adaptation
- (2013) Brendan Egan et al. Cell Metabolism
- Lactate Receptor Sites Link Neurotransmission, Neurovascular Coupling, and Brain Energy Metabolism
- (2013) K. H. Lauritzen et al. CEREBRAL CORTEX
- Lactate Engages Receptor Tyrosine Kinases Axl, Tie2, and Vascular Endothelial Growth Factor Receptor 2 to Activate Phosphoinositide 3-Kinase/Akt and Promote Angiogenesis
- (2013) Guo-Xiang Ruan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration
- (2013) Erik S. Musiek et al. JOURNAL OF CLINICAL INVESTIGATION
- Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy
- (2013) Estelle Woldt et al. NATURE MEDICINE
- FGF21 regulates metabolism and circadian behavior by acting on the nervous system
- (2013) Angie L Bookout et al. NATURE MEDICINE
- Differential regulation of Bdnf expression in cortical neurons by class-selective histone deacetylase inhibitors
- (2013) Indrek Koppel et al. NEUROPHARMACOLOGY
- Metabolism and the Circadian Clock Converge
- (2013) Kristin Eckel-Mahan et al. PHYSIOLOGICAL REVIEWS
- Identification and Validation of Novel Contraction-Regulated Myokines Released from Primary Human Skeletal Muscle Cells
- (2013) Silja Raschke et al. PLoS One
- Acute Exercise Induces FGF21 Expression in Mice and in Healthy Humans
- (2013) Kook Hwan Kim et al. PLoS One
- Skeletal muscle PGC-1 controls whole-body lactate homeostasis through estrogen-related receptor -dependent activation of LDH B and repression of LDH A
- (2013) S. Summermatter et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Physical exercise intervention in depressive disorders: Meta-analysis and systematic review
- (2013) T. Josefsson et al. SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
- Molecular architecture of the mammalian circadian clock
- (2013) Carrie L. Partch et al. TRENDS IN CELL BIOLOGY
- Metabolic signaling by lactate in the brain
- (2013) L. Felipe Barros TRENDS IN NEUROSCIENCES
- Muscle insulin sensitivity and glucose metabolism are controlled by the intrinsic muscle clock
- (2013) Kenneth A. Dyar et al. Molecular Metabolism
- Acute Exercise Remodels Promoter Methylation in Human Skeletal Muscle
- (2012) Romain Barrès et al. Cell Metabolism
- Muscle tissue as an endocrine organ: Comparative secretome profiling of slow-oxidative and fast-glycolytic rat muscle explants and its variation with exercise
- (2012) Arturo Roca-Rivada et al. Journal of Proteomics
- Scheduled Exercise Phase Shifts the Circadian Clock in Skeletal Muscle
- (2012) GRETCHEN WOLFF et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
- (2012) Pontus Boström et al. NATURE
- Muscles, exercise and obesity: skeletal muscle as a secretory organ
- (2012) Bente K. Pedersen et al. Nature Reviews Endocrinology
- Kynurenines in the mammalian brain: when physiology meets pathology
- (2012) Robert Schwarcz et al. NATURE REVIEWS NEUROSCIENCE
- Fndc5 knockdown significantly decreased neural differentiation rate of mouse embryonic stem cells
- (2012) M.-S. Hashemi et al. NEUROSCIENCE
- Control of Sleep and Wakefulness
- (2012) Ritchie E. Brown et al. PHYSIOLOGICAL REVIEWS
- Involvement of PGC-1α in the formation and maintenance of neuronal dendritic spines
- (2012) Aiwu Cheng et al. Nature Communications
- Proteomic identification of secreted proteins from human skeletal muscle cells and expression in response to strength training
- (2011) Frode Norheim et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Cysteine cathepsins: From structure, function and regulation to new frontiers
- (2011) Vito Turk et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Astrocyte-Neuron Lactate Transport Is Required for Long-Term Memory Formation
- (2011) Akinobu Suzuki et al. CELL
- The Unfolded Protein Response Mediates Adaptation to Exercise in Skeletal Muscle through a PGC-1α/ATF6α Complex
- (2011) Jun Wu et al. Cell Metabolism
- Fibroblast Growth Factor 21 (FGF21) in Human Cerebrospinal Fluid
- (2011) Bee K. Tan et al. DIABETES
- Cytokines and brain excitability
- (2011) Michael A. Galic et al. FRONTIERS IN NEUROENDOCRINOLOGY
- Circadian Regulation of ATP Release in Astrocytes
- (2011) L. Marpegan et al. JOURNAL OF NEUROSCIENCE
- Brain glycogen supercompensation following exhaustive exercise
- (2011) Takashi Matsui et al. JOURNAL OF PHYSIOLOGY-LONDON
- Endurance factors improve hippocampal neurogenesis and spatial memory in mice
- (2011) T. Kobilo et al. LEARNING & MEMORY
- Human Muscle Proteome Modifications after Acute or Repeated Eccentric Exercises
- (2011) STÉPHANIE HODY et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
- (2011) Helga Ellingsgaard et al. NATURE MEDICINE
- A circadian clock in hippocampus is regulated by interaction between oligophrenin-1 and Rev-erbα
- (2011) Pamela Valnegri et al. NATURE NEUROSCIENCE
- Exercise training increases size of hippocampus and improves memory
- (2011) K. I. Erickson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evidence for pleiotropic factors in genetics of the musculoskeletal system
- (2010) David Karasik et al. BONE
- Blood BDNF concentrations reflect brain-tissue BDNF levels across species
- (2010) Anders B. Klein et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Sleep and circadian rhythm disruption in psychiatric and neurodegenerative disease
- (2010) Katharina Wulff et al. NATURE REVIEWS NEUROSCIENCE
- Glial cell line-derived neurotrophic factor protein content in rat skeletal muscle is altered by increased physical activity in vivo and in vitro
- (2010) M.J. McCullough et al. NEUROSCIENCE
- CLOCK and BMAL1 regulate MyoD and are necessary for maintenance of skeletal muscle phenotype and function
- (2010) J. L. Andrews et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metabolic Signatures of Exercise in Human Plasma
- (2010) G. D. Lewis et al. Science Translational Medicine
- The blood-brain barrier and glutamate
- (2009) Richard A Hawkins AMERICAN JOURNAL OF CLINICAL NUTRITION
- Endurance training enhances BDNF release from the human brain
- (2009) Thomas Seifert et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- AMPK and the biochemistry of exercise: implications for human health and disease
- (2009) Erik A. Richter et al. BIOCHEMICAL JOURNAL
- Exercise exerts neuroprotective effects on Parkinson's disease model of rats
- (2009) Naoki Tajiri et al. BRAIN RESEARCH
- Brain-derived neurotrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMP-activated protein kinase
- (2009) V. B. Matthews et al. DIABETOLOGIA
- Role of exercise-induced brain-derived neurotrophic factor production in the regulation of energy homeostasis in mammals
- (2009) Bente K. Pedersen et al. EXPERIMENTAL PHYSIOLOGY
- Evidence for a release of brain-derived neurotrophic factor from the brain during exercise
- (2009) Peter Rasmussen et al. EXPERIMENTAL PHYSIOLOGY
- Control of mammalian gene expression by amino acids, especially glutamine
- (2009) Carole Brasse-Lagnel et al. FEBS Journal
- Temporal dynamics of mouse hippocampal clock gene expression support memory processing
- (2009) Antje Jilg et al. HIPPOCAMPUS
- Aerobic fitness is associated with hippocampal volume in elderly humans
- (2009) Kirk I. Erickson et al. HIPPOCAMPUS
- Aging, exercise, and muscle protein metabolism
- (2009) René Koopman et al. JOURNAL OF APPLIED PHYSIOLOGY
- Blood Lactate is an Important Energy Source for the Human Brain
- (2009) Gerrit van Hall et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Cycling Behavior and Memory Formation
- (2009) J. R. Gerstner et al. JOURNAL OF NEUROSCIENCE
- Effects of exercise and muscle type on BDNF, NT-4/5, and TrKB expression in skeletal muscle
- (2009) Daniel I. Ogborn et al. MUSCLE & NERVE
- Neuronal release of proBDNF
- (2009) Jianmin Yang et al. NATURE NEUROSCIENCE
- PGC-1α negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erbα axis
- (2009) Jennifer L. Estall et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The transcriptional coactivator PGC-1α mediates exercise-induced angiogenesis in skeletal muscle
- (2009) Jessica Chinsomboon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exercise is medicine and physicians need to prescribe it!
- (2008) R E Sallis BRITISH JOURNAL OF SPORTS MEDICINE
- FGF21 is an Akt-regulated myokine
- (2008) Yasuhiro Izumiya et al. FEBS LETTERS
- Neural Progenitor Cells Treated with EPO Induce Angiogenesis through the Production of Vegf
- (2008) Lei Wang et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- The role of exercise and PGC1α in inflammation and chronic disease
- (2008) Christoph Handschin et al. NATURE
- HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α
- (2008) Zoltan Arany et al. NATURE
- Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF
- (2008) Tomoya Matsumoto et al. NATURE NEUROSCIENCE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started