Circadian time signatures of fitness and disease

Clinical and Therapeutic Aspects of Childhood Narcolepsy-Cataplexy: A Retrospective Study of 51 Children

(2017) Adi Aran et al.   SLEEP

Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML

(2016) Rishi V. Puram et al.   CELL

Peripheral Circadian Clocks Mediate Dietary Restriction-Dependent Changes in Lifespan and Fat Metabolism in Drosophila

(2016) Subhash D. Katewa et al.   Cell Metabolism

Circadian Rhythm Disruption Promotes Lung Tumorigenesis

(2016) Thales Papagiannakopoulos et al.   Cell Metabolism

Temperature regulates splicing efficiency of the cold-inducible RNA-binding protein geneCirbp

(2016) Ivana Gotic et al.   GENES & DEVELOPMENT

Chromatin Scanning by Dynamic Binding of Pioneer Factors

(2016) Kenneth S. Zaret et al.   MOLECULAR CELL

Circadian Oscillators: Around the Transcription–Translation Feedback Loop and on to Output

(2016) Jennifer M. Hurley et al.   TRENDS IN BIOCHEMICAL SCIENCES

MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells

(2015) Brian J. Altman et al.   Cell Metabolism

Identification of Circadian Determinants of Cancer Chronotherapy through In Vitro Chronopharmacology and Mathematical Modeling

(2015) S. Dulong et al.   MOLECULAR CANCER THERAPEUTICS

Circadian Oscillation of Sulfiredoxin in the Mitochondria

(2015) In Sup Kil et al.   MOLECULAR CELL

Pancreatic   cell enhancers regulate rhythmic transcription of genes controlling insulin secretion

(2015) M. Perelis et al.   SCIENCE

Discrete functions of nuclear receptor Rev-erb  couple metabolism to the clock

(2015) Y. Zhang et al.   SCIENCE

DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization

(2015) Stephanie J Papp et al.   eLife

Circadian Enhancers Coordinate Multiple Phases of Rhythmic Gene Transcription In Vivo

(2014) Bin Fang et al.   CELL

Temporal orchestration of repressive chromatin modifiers by circadian clock Period complexes

(2014) Hao A Duong et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Impact of circadian misalignment on energy metabolism during simulated nightshift work

(2014) Andrew W. McHill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evening use of light-emitting eReaders negatively affects sleep, circadian timing, and next-morning alertness

(2014) Anne-Marie Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reprogramming of the Circadian Clock by Nutritional Challenge

(2013) Kristin L. Eckel-Mahan et al.   CELL

The CRTC1-SIK1 Pathway Regulates Entrainment of the Circadian Clock

(2013) Aarti Jagannath et al.   CELL

SIRT1 Mediates Central Circadian Control in the SCN by a Mechanism that Decays with Aging

(2013) Hung-Chun Chang et al.   CELL

Blood-Borne Circadian Signal Stimulates Daily Oscillations in Actin Dynamics and SRF Activity

(2013) Alan Gerber et al.   CELL

Circadian Clock NAD+ Cycle Drives Mitochondrial Oxidative Metabolism in Mice

(2013) C. B. Peek et al.   SCIENCE

Molecular architecture of the mammalian circadian clock

(2013) Carrie L. Partch et al.   TRENDS IN CELL BIOLOGY

Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet

(2012) Megumi Hatori et al.   Cell Metabolism

Small molecule modifiers of circadian clocks

(2012) Zheng Chen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Social Jetlag and Obesity

(2012) Till Roenneberg et al.   CURRENT BIOLOGY

Genetic basis of human circadian rhythm disorders

(2012) Christopher R. Jones et al.   EXPERIMENTAL NEUROLOGY

Simulated body temperature rhythms reveal the phase-shifting behavior and plasticity of mammalian circadian oscillators

(2012) C. Saini et al.   GENES & DEVELOPMENT

Circadian control of mRNA polyadenylation dynamics regulates rhythmic protein expression

(2012) S. Kojima et al.   GENES & DEVELOPMENT

Peroxiredoxins are conserved markers of circadian rhythms

(2012) Rachel S. Edgar et al.   NATURE

Circadian Rhythm of Redox State Regulates Excitability in Suprachiasmatic Nucleus Neurons

(2012) T. A. Wang et al.   SCIENCE

Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals

(2012) N. Koike et al.   SCIENCE

Adverse Metabolic Consequences in Humans of Prolonged Sleep Restriction Combined with Circadian Disruption

(2012) O. M. Buxton et al.   Science Translational Medicine

Nascent-Seq reveals novel features of mouse circadian transcriptional regulation

(2012) Jerome S Menet et al.   eLife

Age-Related Decline in Circadian Output

(2011) T. J. Nakamura et al.   JOURNAL OF NEUROSCIENCE

The circadian molecular clock creates epidermal stem cell heterogeneity

(2011) Peggy Janich et al.   NATURE

Cryptochromes mediate rhythmic repression of the glucocorticoid receptor

(2011) Katja A. Lamia et al.   NATURE

Tissue-intrinsic dysfunction of circadian clock confers transplant arteriosclerosis

(2011) B. Cheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of skin cancer by the circadian rhythm

(2011) S. Gaddameedhi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone Lysine Demethylase JARID1a Activates CLOCK-BMAL1 and Influences the Circadian Clock

(2011) L. DiTacchio et al.   SCIENCE

A Circadian Rhythm Orchestrated by Histone Deacetylase 3 Controls Hepatic Lipid Metabolism

(2011) D. Feng et al.   SCIENCE

Meal timing and composition influence ghrelin levels, appetite scores and weight loss maintenance in overweight and obese adults

(2011) Daniela Jakubowicz et al.   STEROIDS

Genome-Wide and Phase-Specific DNA-Binding Rhythms of BMAL1 Control Circadian Output Functions in Mouse Liver

(2011) Guillaume Rey et al.   PLOS BIOLOGY

Rotating Night Shift Work and Risk of Type 2 Diabetes: Two Prospective Cohort Studies in Women

(2011) An Pan et al.   PLOS MEDICINE

Mammalian Per-Arnt-Sim Proteins in Environmental Adaptation

(2010) Brian E. McIntosh et al.   Annual Review of Physiology

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

(2010) Biliana Marcheva et al.   NATURE

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

(2010) Josée Dupuis et al.   NATURE GENETICS

Temperature as a Universal Resetting Cue for Mammalian Circadian Oscillators

(2010) E. D. Buhr et al.   SCIENCE

A Role for Casein Kinase 2 in the Mechanism Underlying Circadian Temperature Compensation

(2009) Arun Mehra et al.   CELL

Enhanced Orexin Receptor-2 Signaling Prevents Diet-Induced Obesity and Improves Leptin Sensitivity

(2009) Hiromasa Funato et al.   Cell Metabolism

Circadian Timing of Food Intake Contributes to Weight Gain

(2009) Deanna M. Arble et al.   Obesity

Loss of cryptochrome reduces cancer risk inp53mutant mice

(2009) Nuri Ozturk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1

(2009) Y. Nakahata et al.   SCIENCE

Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD+ Biosynthesis

(2009) K. M. Ramsey et al.   SCIENCE

The Transcriptional Repressor DEC2 Regulates Sleep Length in Mammals

(2009) Y. He et al.   SCIENCE

The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control

(2008) Yasukazu Nakahata et al.   CELL

SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation

(2008) Gad Asher et al.   CELL

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

(2008) Nabila Bouatia-Naji et al.   NATURE GENETICS