标题
The BMP Pathway and Its Inhibitors in the Skeleton
作者
关键词
-
出版物
PHYSIOLOGICAL REVIEWS
Volume 98, Issue 4, Pages 2431-2452
出版商
American Physiological Society
发表日期
2018-08-29
DOI
10.1152/physrev.00028.2017
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Alternative cleavage of the bone morphogenetic protein (BMP), Gbb, produces ligands with distinct developmental functions and receptor preferences
- (2017) Edward N. Anderson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activin receptor type 2A (ACVR2A) functions directly in osteoblasts as a negative regulator of bone mass
- (2017) Brian C. Goh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bone Morphogenetic Protein
- (2017) Eric A. Barcak et al. ORTHOPEDIC CLINICS OF NORTH AMERICA
- Bone Morphogenetic Proteins in Vascular Homeostasis and Disease
- (2017) Marie-José Goumans et al. Cold Spring Harbor Perspectives in Biology
- Bone Morphogenetic Protein–Based Therapeutic Approaches
- (2017) Jonathan W. Lowery et al. Cold Spring Harbor Perspectives in Biology
- Bone morphogenetic proteins in inflammation, glucose homeostasis and adipose tissue energy metabolism
- (2016) Lovorka Grgurevic et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Transient Local Bone Remodeling Effects of rhBMP-2 in an Ovine Interbody Spine Fusion Model
- (2016) Hyun W. Bae et al. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
- BMP signalling in skeletal development, disease and repair
- (2016) Valerie S. Salazar et al. Nature Reviews Endocrinology
- Agonists and Antagonists of TGF-β Family Ligands
- (2016) Chenbei Chang Cold Spring Harbor Perspectives in Biology
- Bone Morphogenetic Proteins
- (2016) Takenobu Katagiri et al. Cold Spring Harbor Perspectives in Biology
- Signaling Cross Talk between TGF-β/Smad and Other Signaling Pathways
- (2016) Kunxin Luo Cold Spring Harbor Perspectives in Biology
- Regulation of TGF-β Family Signaling by Inhibitory Smads
- (2016) Keiji Miyazawa et al. Cold Spring Harbor Perspectives in Biology
- Epidemiology of Fracture Nonunion in 18 Human Bones
- (2016) Robert Zura et al. JAMA Surgery
- A Survey of Strategies to Modulate the Bone Morphogenetic Protein Signaling Pathway: Current and Future Perspectives
- (2016) Jonathan W. Lowery et al. Stem Cells International
- Bmp2 conditional knockout in osteoblasts and endothelial cells does not impair bone formation after injury or mechanical loading in adult mice
- (2015) Sarah Howe McBride-Gagyi et al. BONE
- BMP–Smad4 signaling is required for precartilaginous mesenchymal condensation independent of Sox9 in the mouse
- (2015) Joohyun Lim et al. DEVELOPMENTAL BIOLOGY
- The Type I BMP Receptor ACVR1/ALK2 is Required for Chondrogenesis During Development
- (2015) Diana Rigueur et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Loss of BMPR2 leads to high bone mass due to increased osteoblast activity
- (2015) J. W. Lowery et al. JOURNAL OF CELL SCIENCE
- The prodomain of BMP4 is necessary and sufficient to generate stable BMP4/7 heterodimers with enhanced bioactivity in vivo
- (2015) Judith M. Neugebauer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neofunction of ACVR1 in fibrodysplasia ossificans progressiva
- (2015) Kyosuke Hino et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Expression and purification of active recombinant human bone morphogenetic 7-2 dimer fusion protein
- (2015) Jianli Dang et al. PROTEIN EXPRESSION AND PURIFICATION
- ACVR1 R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A
- (2015) Sarah J. Hatsell et al. Science Translational Medicine
- The bone morphogenetic protein-2/7 heterodimer is a stronger inducer of bone regeneration than the individual homodimers in a rat spinal fusion model
- (2015) Tokimitsu Morimoto et al. Spine Journal
- Bone Morphogenetic Protein for the Healing of Tibial Fracture: A Meta-Analysis of Randomized Controlled Trials
- (2015) Jiezhi Dai et al. PLoS One
- Mesenchymal stem cells from osteoporotic patients reveal reduced migration and invasion upon stimulation with BMP-2 or BMP-7
- (2014) Florian Haasters et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- BMP-2 and titanium particles synergistically activate osteoclast formation
- (2014) S.X. Sun et al. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
- Systemically available bone morphogenetic protein two and seven affect bone metabolism
- (2014) Ivo Dumic-Cule et al. INTERNATIONAL ORTHOPAEDICS
- GATA4 Is Essential for Bone Mineralization via ERα and TGFβ/BMP Pathways
- (2014) Miriam Güemes et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Dynamics and Cellular Localization ofBmp2,Bmp4, andNogginTranscription in the Postnatal Mouse Skeleton
- (2014) Steven K Pregizer et al. JOURNAL OF BONE AND MINERAL RESEARCH
- The Recent Prevalence of Osteoporosis and Low Bone Mass in the United States Based on Bone Mineral Density at the Femoral Neck or Lumbar Spine
- (2014) Nicole C Wright et al. JOURNAL OF BONE AND MINERAL RESEARCH
- MicroRNA-302a Stimulates Osteoblastic Differentiation by Repressing COUP-TFII Expression
- (2014) In-Hong Kang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Optimizing the osteogenic differentiation of human mesenchymal stromal cells by the synergistic action of growth factors
- (2014) Yahya Açil et al. JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY
- Bone substitutes in orthopaedic surgery: from basic science to clinical practice
- (2014) V. Campana et al. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
- Systemic Injection of CK2.3, a Novel Peptide Acting Downstream of Bone Morphogenetic Protein Receptor BMPRIa, Leads to Increased Trabecular Bone Mass
- (2014) Hemanth Akkiraju et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Fracture healing: mechanisms and interventions
- (2014) Thomas A. Einhorn et al. Nature Reviews Rheumatology
- Long Bone Structure and Strength Depend on BMP2 from Osteoblasts and Osteocytes, but Not Vascular Endothelial Cells
- (2014) Sarah H. McBride et al. PLoS One
- Regulation of TGFβ and related signals by precursor processing
- (2014) Daniel B. Constam SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Expansion of Murine Periosteal Progenitor Cells with Fibroblast Growth Factor 2 Reveals an Intrinsic Endochondral Ossification Program Mediated by Bone Morphogenetic Protein 2
- (2014) Nick van Gastel et al. STEM CELLS
- miR-542-3p suppresses osteoblast cell proliferation and differentiation, targets BMP-7 signaling and inhibits bone formation
- (2014) J Kureel et al. Cell Death & Disease
- Selective Small Molecule Compounds Increase BMP-2 Responsiveness by Inhibiting Smurf1-mediated Smad1/5 Degradation
- (2014) Yu Cao et al. Scientific Reports
- Smad9 is a new type of transcriptional regulator in bone morphogenetic protein signaling
- (2014) S. Tsukamoto et al. Scientific Reports
- Bone regenerative medicine: classic options, novel strategies, and future directions
- (2014) Ahmad Oryan et al. Journal of Orthopaedic Surgery and Research
- Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis
- (2014) Amanda B. Core et al. Frontiers in Pharmacology
- Interactions between FGF21 and BMP-2 in osteogenesis
- (2013) Kazunari Ishida et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mesenchymal stem cells from osteoporotic patients feature impaired signal transduction but sustained osteoinduction in response to BMP-2 stimulation
- (2013) Wolf Christian Prall et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- New insights in osteogenic differentiation revealed by mass spectrometric assessment of phosphorylated substrates in murine skin mesenchymal cells
- (2013) Erik Halcsik et al. BMC CELL BIOLOGY
- A myostatin and activin decoy receptor enhances bone formation in mice
- (2013) P. Bialek et al. BONE
- Activins bind and signal via bone morphogenetic protein receptor type II (BMPR2) in immortalized gonadotrope-like cells
- (2013) Carlis A. Rejon et al. CELLULAR SIGNALLING
- Bone morphogenetic protein-9 activates Smad and ERK pathways and supports human osteoclast function and survival in vitro
- (2013) David Fong et al. CELLULAR SIGNALLING
- Smad7 regulates terminal maturation of chondrocytes in the growth plate
- (2013) Kristine D. Estrada et al. DEVELOPMENTAL BIOLOGY
- Marker Gene Screening for Human Mesenchymal Stem Cells in Early Osteogenic Response to Bone Morphogenetic Protein 6 with DNA Microarray
- (2013) Shien Zou et al. Genetic Testing and Molecular Biomarkers
- Fibroblast growth factor 2 inhibits bone morphogenetic protein 9-induced osteogenic differentiation of mesenchymal stem cells by repressing Smads signaling and subsequently reducing Smads dependent up-regulation of ALK1 and ALK2
- (2013) Tao Song et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Bone Morphogenetic Proteins Signal Via SMAD and Mitogen-activated Protein (MAP) Kinase Pathways at Distinct Times during Osteoclastogenesis
- (2013) Aaron Broege et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ligand- and Stage-Dependent Divergent Functions of BMP Signaling in the Differentiation of Embryonic Skeletogenic Progenitors In Vitro
- (2013) Carlos I Lorda-Diez et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Postnatal ablation of osteoblast Smad4 enhances proliferative responses to canonical Wnt signaling through interactions with β-catenin
- (2013) Valerie S. Salazar et al. JOURNAL OF CELL SCIENCE
- Embryonic ablation of osteoblast Smad4 interrupts matrix synthesis in response to canonical Wnt signaling and causes an osteogenesis-imperfecta-like phenotype
- (2013) V. S. Salazar et al. JOURNAL OF CELL SCIENCE
- Bmp2 in osteoblasts of periosteum and trabecular bone links bone formation to vascularization and mesenchymal stem cells
- (2013) W. Yang et al. JOURNAL OF CELL SCIENCE
- Multiple-dose, safety, pharmacokinetic, and pharmacodynamic study of sotatercept (ActRIIA-IgG1), a novel erythropoietic agent, in healthy postmenopausal women
- (2013) Matthew L. Sherman et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Noggin resistance contributes to the potent osteogenic capability of BMP9 in mesenchymal stem cells
- (2013) Yi Wang et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Fibroblast Growth Factor-2 and Bone Morphogenetic Protein-2 Have a Synergistic Stimulatory Effect on Bone Formation in Cell Cultures From Elderly Mouse and Human Bone
- (2013) L. T. Kuhn et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Activin A Suppresses Osteoblast Mineralization Capacity by Altering Extracellular Matrix (ECM) Composition and Impairing Matrix Vesicle (MV) Production
- (2013) Rodrigo D. A. M. Alves et al. MOLECULAR & CELLULAR PROTEOMICS
- An Antibody Blocking Activin Type II Receptors Induces Strong Skeletal Muscle Hypertrophy and Protects from Atrophy
- (2013) E. Lach-Trifilieff et al. MOLECULAR AND CELLULAR BIOLOGY
- Expression profiling of lncRNAs in C3H10T1/2 mesenchymal stem cells undergoing early osteoblast differentiation
- (2013) CHANGQING ZUO et al. Molecular Medicine Reports
- BMP activation and Wnt-signalling affect biochemistry and functional biomechanical properties of cartilage tissue engineering constructs
- (2013) A. Krase et al. OSTEOARTHRITIS AND CARTILAGE
- Comparative Genomics Identifies the Mouse Bmp3 Promoter and an Upstream Evolutionary Conserved Region (ECR) in Mammals
- (2013) Jonathan W. Lowery et al. PLoS One
- Pin1 Null Mice Exhibit Low Bone Mass and Attenuation of BMP Signaling
- (2013) Zhong-Jian Shen et al. PLoS One
- Deficiency of Retinaldehyde Dehydrogenase 1 Induces BMP2 and Increases Bone Mass In Vivo
- (2013) Shriram Nallamshetty et al. PLoS One
- Heterodimeric BMP-2/7 Antagonizes the Inhibition of All-Trans Retinoic Acid and Promotes the Osteoblastogenesis
- (2013) Wenjuan Bi et al. PLoS One
- Beyond osteogenesis: an in vitro comparison of the potentials of six bone morphogenetic proteins
- (2013) Jessica C. Rivera et al. Frontiers in Pharmacology
- Fibroblast growth factor 2 inhibits up-regulation of bone morphogenic proteins and their receptors during osteoblastic differentiation of human mesenchymal stem cells
- (2012) Emmanuel Biver et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Control of osteogenesis by the canonical Wnt and BMP pathways in vivo
- (2012) Sylvain Marcellini et al. BIOESSAYS
- Skeletal Morphogenesis during Embryonic Development
- (2012) Yingzi Yang CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION
- Smad4 is required to induce digit ray primordia and to initiate the aggregation and differentiation of chondrogenic progenitors in mouse limb buds
- (2012) J.-D. Benazet et al. DEVELOPMENT
- Activin A and cardiovascular disease in type 2 diabetes mellitus
- (2012) Thor Ueland et al. Diabetes & Vascular Disease Research
- Conditional Inactivation of Noggin in the Postnatal Skeleton Causes Osteopenia
- (2012) Ernesto Canalis et al. ENDOCRINOLOGY
- Effects of the activin A–myostatin–follistatin system on aging bone and muscle progenitor cells
- (2012) Matthew Bowser et al. EXPERIMENTAL GERONTOLOGY
- Structural studies of the TGF-βs and their receptors - insights into evolution of the TGF-β superfamily
- (2012) Andrew P. Hinck FEBS LETTERS
- Chondrocyte BMP2 signaling plays an essential role in bone fracture healing
- (2012) Meng Mi et al. GENE
- Regulation of bone and cartilage development by network between BMP signalling and transcription factors
- (2012) R. Nishimura et al. JOURNAL OF BIOCHEMISTRY
- SMADversusNon-SMAD Signaling Is Determined by Lateral Mobility of Bone Morphogenetic Protein (BMP) Receptors
- (2012) Asja Guzman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of Osteoclast Generation: A Novel Function of the Bone Morphogenetic Protein 7/Osteogenic Protein 1
- (2012) Thomas Maurer et al. MEDIATORS OF INFLAMMATION
- A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength
- (2012) Marc Baud’huin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of TGF-β receptor activity
- (2012) Fei Huang et al. Cell and Bioscience
- Loss-of-function of ACVR1 in osteoblasts increases bone mass and activates canonical Wnt signaling through suppression of Wnt inhibitors SOST and DKK1
- (2011) Nobuhiro Kamiya et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Time series gene expression profiling and temporal regulatory pathway analysis of BMP6 induced osteoblast differentiation and mineralization
- (2011) Weijun Luo et al. BMC Systems Biology
- The myogenic transcriptional network
- (2011) Shigetoshi Yokoyama et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Cooperative activity of noggin and gremlin 1 in axial skeleton development
- (2011) D. A. Stafford et al. DEVELOPMENT
- BMPR-II is dispensable for formation of the limb skeleton
- (2011) Laura W. Gamer et al. GENESIS
- Divergent activities of osteogenic BMP2, and tenogenic BMP12 and BMP13 independent of receptor binding affinities
- (2011) Stephen P. Berasi et al. GROWTH FACTORS
- Smad6 is essential to limit BMP signaling during cartilage development
- (2011) Kristine D Estrada et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Conditional deletion of Bmpr1a in differentiated osteoclasts increases osteoblastic bone formation, increasing volume of remodeling bone in mice
- (2011) Mina Okamoto et al. JOURNAL OF BONE AND MINERAL RESEARCH
- BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development
- (2011) B. Shu et al. JOURNAL OF CELL SCIENCE
- Integration of BMP, Wnt, and notch signaling pathways in osteoblast differentiation
- (2011) Grace L. Lin et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Homeodomain transcription factors regulate BMP-2-induced osteoactivin transcription in osteoblasts
- (2011) Maneet Singh et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Functional redundancy of type II BMP receptor and type IIB activin receptor in BMP2-induced osteoblast differentiation
- (2011) Hongbin Liu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The roles of activin A and its binding protein, follistatin, in inflammation and tissue repair
- (2011) David M. de Kretser et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- BMP3 Suppresses Osteoblast Differentiation of Bone Marrow Stromal Cells via Interaction with Acvr2b
- (2011) Shoichiro Kokabu et al. MOLECULAR ENDOCRINOLOGY
- Self-complementary AAV2.5-BMP2-coated Femoral Allografts Mediated Superior Bone Healing Versus Live Autografts in Mice With Equivalent Biomechanics to Unfractured Femur
- (2011) Cemal Yazici et al. MOLECULAR THERAPY
- The BMP2/7 heterodimer inhibits the human breast cancer stem cell subpopulation and bone metastases formation
- (2011) J T Buijs et al. ONCOGENE
- Smad1 plays an essential role in bone development and postnatal bone formation
- (2011) M. Wang et al. OSTEOARTHRITIS AND CARTILAGE
- Interaction of TGFβ and BMP Signaling Pathways during Chondrogenesis
- (2011) Bettina Keller et al. PLoS One
- Spatial Segregation of BMP/Smad Signaling Affects Osteoblast Differentiation in C2C12 Cells
- (2011) Eva Heining et al. PLoS One
- Brief Review of Models of Ectopic Bone Formation
- (2011) Michelle A. Scott et al. STEM CELLS AND DEVELOPMENT
- BMP2/7 Heterodimer Can Modulate All Cellular Events of the In Vitro RANKL-Mediated Osteoclastogenesis, Respectively, in Different Dose Patterns
- (2011) Yuanna Zheng et al. TISSUE ENGINEERING PART A
- Generation of a mouse model with expression of bone morphogenetic protein type II receptor lacking the cytoplasmic domain in osteoblasts
- (2010) Chaozhe Yang et al. Annals of the New York Academy of Sciences
- Site-Specific PEGylation of Bone Morphogenetic Protein-2 Cysteine Analogues
- (2010) Junli Hu et al. BIOCONJUGATE CHEMISTRY
- A soluble activin receptor Type IIA fusion protein (ACE-011) increases bone mass via a dual anabolic-antiresorptive effect in Cynomolgus monkeys
- (2010) Sutada Lotinun et al. BONE
- BMP signaling in vascular development and disease
- (2010) Jonathan W. Lowery et al. CYTOKINE & GROWTH FACTOR REVIEWS
- A Soluble Activin Receptor Type IIB Prevents the Effects of Androgen Deprivation on Body Composition and Bone Health
- (2010) Alan Koncarevic et al. ENDOCRINOLOGY
- Identification of a Key Residue Mediating Bone Morphogenetic Protein (BMP)-6 Resistance to Noggin Inhibition Allows for Engineered BMPs with Superior Agonist Activity
- (2010) Kening Song et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prodomains of Transforming Growth Factor β (TGFβ) Superfamily Members Specify Different Functions
- (2010) Gerhard Sengle et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Characterization of the Ligand Binding Functionality of the Extracellular Domain of Activin Receptor Type IIB
- (2010) Dianne Sako et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- BMP2-activated Erk/MAP Kinase Stabilizes Runx2 by Increasing p300 Levels and Histone Acetyltransferase Activity
- (2010) Ji Hae Jun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- rhBMP-2 Induces Transient Bone Resorption Followed by Bone Formation in a Nonhuman Primate Core-Defect Model
- (2010) Howard J. Seeherman et al. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
- Inhibition of TGF-β signaling by 1D11 antibody treatment increases bone mass and quality in vivo
- (2010) James R Edwards et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Virtual screening and selection of drug-like compounds to block noggin interaction with bone morphogenetic proteins
- (2010) Shaila Ahmed et al. JOURNAL OF MOLECULAR GRAPHICS & MODELLING
- Bone morphogenetic proteins 2, 5, and 6 in combination stimulate osteoblasts but not osteoclasts in vitro
- (2010) Arno Wutzl et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- A synthetic compound that potentiates bone morphogenetic protein-2-induced transdifferentiation of myoblasts into the osteoblastic phenotype
- (2010) Satoshi Kato et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Bone Morphogenetic Protein-2 and -6 Heterodimer Illustrates the Nature of Ligand-Receptor Assembly
- (2010) Michael J. Isaacs et al. MOLECULAR ENDOCRINOLOGY
- BMP-2/6 Heterodimer Is More Effective than BMP-2 or BMP-6 Homodimers as Inductor of Differentiation of Human Embryonic Stem Cells
- (2010) Elvira Valera et al. PLoS One
- Extracellular BMP-antagonist regulation in development and disease: tied up in knots
- (2010) David W. Walsh et al. TRENDS IN CELL BIOLOGY
- Osteogenic Responses to Different Concentrations/Ratios of BMP-2 and bFGF in Bone Formation
- (2009) Lei Wang et al. ANNALS OF BIOMEDICAL ENGINEERING
- Receptor oligomerization and beyond: a case study in bone morphogenetic proteins
- (2009) Kai Heinecke et al. BMC BIOLOGY
- New insights into BMP-7 mediated osteoblastic differentiation of primary human mesenchymal stem cells
- (2009) Karen Lavery et al. BONE
- Treatment with a soluble receptor for activin improves bone mass and structure in the axial and appendicular skeleton of female cynomolgus macaques (Macaca fascicularis)
- (2009) Roberto José Fajardo et al. BONE
- Osteo-transcriptomics of human mesenchymal stem cells: Accelerated gene expression and osteoblast differentiation induced by vitamin D reveals c-MYC as an enhancer of BMP2-induced osteogenesis
- (2009) Ester Piek et al. BONE
- Development and optimization of a cell-based assay for the selection of synthetic compounds that potentiate bone morphogenetic protein-2 activity
- (2009) Motohiro Okada et al. CELL BIOCHEMISTRY AND FUNCTION
- Activin and related proteins in inflammation: Not just interested bystanders
- (2009) David J. Phillips et al. CYTOKINE & GROWTH FACTOR REVIEWS
- BMP2 signaling in bone development and repair
- (2009) Vicki Rosen CYTOKINE & GROWTH FACTOR REVIEWS
- BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation
- (2009) K. N. Retting et al. DEVELOPMENT
- Nephroblastoma Overexpressed (Nov) Inactivation Sensitizes Osteoblasts to Bone Morphogenetic Protein-2, But Nov Is Dispensable for Skeletal Homeostasis
- (2009) Ernesto Canalis et al. ENDOCRINOLOGY
- Endogenous bone morphogenetic proteins in human bone marrow-derived multipotent mesenchymal stromal cells
- (2009) F. Philipp Seib et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- A comparative study on BMP-induced osteoclastogenesis and osteoblastogenesis in primary cultures of adult rat bone marrow cells
- (2009) Sangita Paul et al. GROWTH FACTORS
- Molecular Regulation of Matrix Extracellular Phosphoglycoprotein Expression by Bone Morphogenetic Protein-2
- (2009) Young-Dan Cho et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Enhanced Osteoclastogenesis Causes Osteopenia in Twisted Gastrulation-Deficient Mice Through Increased BMP Signaling
- (2009) Julio E Sotillo Rodriguez et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Sustained BMP Signaling in Osteoblasts Stimulates Bone Formation by Promoting Angiogenesis and Osteoblast Differentiation
- (2009) Fengjie Zhang et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts
- (2009) Nobuhiro Kamiya et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Axin2 controls bone remodeling through the -catenin-BMP signaling pathway in adult mice
- (2009) Y. Yan et al. JOURNAL OF CELL SCIENCE
- Bone morphogenic protein 2 directly enhances differentiation of murine osteoclast precursors
- (2009) Eric D. Jensen et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Sustained and localized in vitro release of BMP-2/7, RANKL, and tetracycline from Flexbone, an elastomeric osteoconductive bone substitute
- (2009) Jianwen Xu et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- ‘Two-Stage Double-Technique Hybrid (TSDTH)’ Identification Strategy for the Analysis of BMP2-Induced Transdifferentiation of Premyoblast C2C12 Cells to Osteoblast
- (2009) Byung-Gyu Kim et al. JOURNAL OF PROTEOME RESEARCH
- Id1 Represses Osteoclast-Dependent Transcription and Affects Bone Formation and Hematopoiesis
- (2009) April S. Chan et al. PLoS One
- Short-term Osteoclastic Activity Induced by Locally High Concentrations of Recombinant Human Bone Morphogenetic Protein–2 in a Cancellous Bone Environment
- (2009) Jeffrey M. Toth et al. SPINE
- Non-Smad pathways in TGF-β signaling
- (2008) Ying E Zhang CELL RESEARCH
- BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway
- (2008) N. Kamiya et al. DEVELOPMENT
- BMP4 Is Dispensable for Skeletogenesis and Fracture-Healing in the Limb
- (2008) Kunikazu Tsuji et al. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
- Osteocyte-Derived Sclerostin Inhibits Bone Formation: Its Role in Bone Morphogenetic Protein and Wnt Signaling
- (2008) Peter ten Dijke et al. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
- Disruption of BMP Signaling in Osteoblasts Through Type IA Receptor (BMPRIA) Increases Bone Mass*
- (2008) Nobuhiro Kamiya et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Single-Dose, Randomized, Double-Blind, Placebo-Controlled Study of ACE-011 (ActRIIA-IgG1) in Postmenopausal Women*
- (2008) Jon Ruckle et al. JOURNAL OF BONE AND MINERAL RESEARCH
- A New Model for Growth Factor Activation: Type II Receptors Compete with the Prodomain for BMP-7
- (2008) Gerhard Sengle et al. JOURNAL OF MOLECULAR BIOLOGY
- Accelerated hypertrophic chondrocyte kinetics in GDF-7 deficient murine tibial growth plates
- (2008) Borjana Mikic et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Cooperative Assembly of TGF-β Superfamily Signaling Complexes Is Mediated by Two Disparate Mechanisms and Distinct Modes of Receptor Binding
- (2008) Jay Groppe et al. MOLECULAR CELL
- SMAD proteins control DROSHA-mediated microRNA maturation
- (2008) Brandi N. Davis et al. NATURE
- BMP type I receptor inhibition reduces heterotopic ossification
- (2008) Paul B Yu et al. NATURE MEDICINE
- A soluble activin Type IIA receptor induces bone formation and improves skeletal integrity
- (2008) R. S. Pearsall et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A microRNA signature for a BMP2-induced osteoblast lineage commitment program
- (2008) Z. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Expression, purification and osteogenic bioactivity of recombinant human BMP-4, -9, -10, -11 and -14
- (2008) P.C. Bessa et al. PROTEIN EXPRESSION AND PURIFICATION
- A Comprehensive Analysis of the Dual Roles of BMPs in Regulating Adipogenic and Osteogenic Differentiation of Mesenchymal Progenitor Cells
- (2008) Quan Kang et al. STEM CELLS AND DEVELOPMENT
- Effects of low intensity pulsed ultrasound with and without increased cortical porosity on structural bone allograft incorporation
- (2008) Brandon G Santoni et al. Journal of Orthopaedic Surgery and Research
- Reduced expression and function of bone morphogenetic protein-2 in bones of Fgf2 null mice
- (2007) Takahiro Naganawa et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Essential Requirement of BMPs-2/4 for Both Osteoblast and Osteoclast Formation in Murine Bone Marrow Cultures from Adult Mice: Antagonism by Noggin
- (2006) Etsuko Abe et al. JOURNAL OF BONE AND MINERAL RESEARCH
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started