标题
BMP signalling in skeletal development, disease and repair
作者
关键词
-
出版物
Nature Reviews Endocrinology
Volume 12, Issue 4, Pages 203-221
出版商
Springer Nature
发表日期
2016-02-19
DOI
10.1038/nrendo.2016.12
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Myhre syndrome: Clinical features and restrictive cardiopulmonary complications
- (2015) Lois J. Starr et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Nosology and classification of genetic skeletal disorders: 2015 revision
- (2015) Luisa Bonafe et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- A Novel Missense Mutation of NOG Interferes With the Dimerization of NOG and Causes Proximal Symphalangism Syndrome in a Chinese Family
- (2015) Xiuhong Pang et al. ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY
- GDF-5 can act as a context-dependent BMP-2 antagonist
- (2015) Uwe Klammert et al. BMC BIOLOGY
- Bone morphogenetic protein signaling in bone homeostasis
- (2015) Gonzalo Sánchez-Duffhues et al. BONE
- Bmp2 conditional knockout in osteoblasts and endothelial cells does not impair bone formation after injury or mechanical loading in adult mice
- (2015) Sarah Howe McBride-Gagyi et al. BONE
- GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration
- (2015) Marc A. Egerman et al. Cell Metabolism
- GDF11 Does Not Rescue Aging-Related Pathological HypertrophyNovelty and Significance
- (2015) Shavonn C. Smith et al. CIRCULATION RESEARCH
- On the development of the patella
- (2015) S. Eyal et al. DEVELOPMENT
- Precise spatial restriction of BMP signaling is essential for articular cartilage differentiation
- (2015) A. Ray et al. DEVELOPMENT
- BMP–Smad4 signaling is required for precartilaginous mesenchymal condensation independent of Sox9 in the mouse
- (2015) Joohyun Lim et al. DEVELOPMENTAL BIOLOGY
- Gdf5 progenitors give rise to fibrocartilage cells that mineralize via hedgehog signaling to form the zonal enthesis
- (2015) Nathaniel A. Dyment et al. DEVELOPMENTAL BIOLOGY
- Elimination of BMP7 from the developing limb mesenchyme leads to articular cartilage degeneration and synovial inflammation with increased age
- (2015) Kahaer Abula et al. FEBS LETTERS
- The Type I BMP Receptor ACVR1/ALK2 is Required for Chondrogenesis During Development
- (2015) Diana Rigueur et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Fibrillin-1 Regulates Skeletal Stem Cell Differentiation by Modulating TGFβ Activity Within the Marrow Niche
- (2015) Silvia Smaldone et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Loss of BMPR2 leads to high bone mass due to increased osteoblast activity
- (2015) J. W. Lowery et al. JOURNAL OF CELL SCIENCE
- Bmp2 Deletion Causes an Amelogenesis Imperfecta Phenotype Via Regulating Enamel Gene Expression
- (2015) Feng Guo et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Routine use of recombinant human bone morphogenetic protein–2 in posterior fusions of the pediatric spine and incidence of cancer
- (2015) Christina Sayama et al. Journal of Neurosurgery-Pediatrics
- A comprehensive assessment of the risk of bone morphogenetic protein use in spinal fusion surgery and postoperative cancer diagnosis
- (2015) Kevin S. Cahill et al. JOURNAL OF NEUROSURGERY-SPINE
- Generation of articular chondrocytes from human pluripotent stem cells
- (2015) April M Craft et al. NATURE BIOTECHNOLOGY
- Excess TGF-β mediates muscle weakness associated with bone metastases in mice
- (2015) David L Waning et al. NATURE MEDICINE
- ACVR1 R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A
- (2015) Sarah J. Hatsell et al. Science Translational Medicine
- Temporally coordinated signals progressively pattern the anteroposterior and dorsoventral body axes
- (2015) Francesca B. Tuazon et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- BMP signalling: agony and antagony in the family
- (2015) Derek P. Brazil et al. TRENDS IN CELL BIOLOGY
- A mutation in the heparin-binding site of noggin as a novel mechanism of proximal symphalangism and conductive hearing loss
- (2014) Sawako Masuda et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Bone morphogenetic proteins and their antagonists: current and emerging clinical uses
- (2014) Imran H A Ali et al. BRITISH JOURNAL OF PHARMACOLOGY
- Osteogenic fate of hypertrophic chondrocytes
- (2014) Guan Yang et al. CELL RESEARCH
- Myhre syndrome
- (2014) C. Le Goff et al. CLINICAL GENETICS
- Dynamics of BMP signaling in limb bud mesenchyme and polydactyly
- (2014) Jacqueline L. Norrie et al. DEVELOPMENTAL BIOLOGY
- Loeys–Dietz syndrome: a primer for diagnosis and management
- (2014) Gretchen MacCarrick et al. GENETICS IN MEDICINE
- Synchrotron imaging reveals bone healing and remodelling strategies in extinct and extant vertebrates
- (2014) J. Anne et al. Journal of the Royal Society Interface
- A subset of chondrogenic cells provides early mesenchymal progenitors in growing bones
- (2014) Noriaki Ono et al. NATURE CELL BIOLOGY
- Excessive transforming growth factor-β signaling is a common mechanism in osteogenesis imperfecta
- (2014) Ingo Grafe et al. NATURE MEDICINE
- Long Bone Structure and Strength Depend on BMP2 from Osteoblasts and Osteocytes, but Not Vascular Endothelial Cells
- (2014) Sarah H. McBride et al. PLoS One
- Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation
- (2014) L. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Restoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle
- (2014) M. Sinha et al. SCIENCE
- To BMP or not to BMP during vertebrate limb bud development
- (2014) Emanuele Pignatti et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Smad9 is a new type of transcriptional regulator in bone morphogenetic protein signaling
- (2014) S. Tsukamoto et al. Scientific Reports
- Chondrocytes Transdifferentiate into Osteoblasts in Endochondral Bone during Development, Postnatal Growth and Fracture Healing in Mice
- (2014) Xin Zhou et al. PLoS Genetics
- Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy
- (2013) Francesco S. Loffredo et al. CELL
- Specification of chondrocytes and cartilage tissues from embryonic stem cells
- (2013) A. M. Craft et al. DEVELOPMENT
- Homozygous missense and nonsense mutations in BMPR1B cause acromesomelic chondrodysplasia-type Grebe
- (2013) Luitgard M Graul-Neumann et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Elevated expression of activins promotes muscle wasting and cachexia
- (2013) Justin L. Chen et al. FASEB JOURNAL
- BMP Receptor 1A Determines the Cell Fate of the Postnatal Growth Plate
- (2013) Junjun Jing et al. International Journal of Biological Sciences
- Embryonic ablation of osteoblast Smad4 interrupts matrix synthesis in response to canonical Wnt signaling and causes an osteogenesis-imperfecta-like phenotype
- (2013) V. S. Salazar et al. JOURNAL OF CELL SCIENCE
- Bmp2 in osteoblasts of periosteum and trabecular bone links bone formation to vascularization and mesenchymal stem cells
- (2013) W. Yang et al. JOURNAL OF CELL SCIENCE
- Multiple phases of chondrocyte enlargement underlie differences in skeletal proportions
- (2013) Kimberly L. Cooper et al. NATURE
- BMP signaling controls muscle mass
- (2013) Roberta Sartori et al. NATURE GENETICS
- Development of the Endochondral Skeleton
- (2013) F. Long et al. Cold Spring Harbor Perspectives in Biology
- Human Developmental Chondrogenesis as a Basis for Engineering Chondrocytes from Pluripotent Stem Cells
- (2013) Ling Wu et al. Stem Cell Reports
- Studies of bone morphogenetic protein-based surgical repair
- (2012) Kevin W.-H. Lo et al. ADVANCED DRUG DELIVERY REVIEWS
- Periosteal BMP2 activity drives bone graft healing
- (2012) Vivianne Chappuis et al. BONE
- Smad4 is required to induce digit ray primordia and to initiate the aggregation and differentiation of chondrogenic progenitors in mouse limb buds
- (2012) J.-D. Benazet et al. DEVELOPMENT
- TGF-β Type II Receptor/MCP-5 Axis: At the Crossroad between Joint and Growth Plate Development
- (2012) Lara Longobardi et al. DEVELOPMENTAL CELL
- Molecular profiling of synovial joints: Use of microarray analysis to identify factors that direct the development of the knee and elbow
- (2012) Dorothy E. Pazin et al. DEVELOPMENTAL DYNAMICS
- Structural studies of the TGF-βs and their receptors - insights into evolution of the TGF-β superfamily
- (2012) Andrew P. Hinck FEBS LETTERS
- Chondrocyte BMP2 signaling plays an essential role in bone fracture healing
- (2012) Meng Mi et al. GENE
- TGFβ signalling in context
- (2012) Joan Massagué NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Bmp2, Bmp4 and Bmp7 Are Co-Required in the Mouse AER for Normal Digit Patterning but Not Limb Outgrowth
- (2012) Kyung-Suk Choi et al. PLoS One
- Joint TGF-β Type II Receptor-Expressing Cells: Ontogeny and Characterization as Joint Progenitors
- (2012) Tieshi Li et al. STEM CELLS AND DEVELOPMENT
- Master Transcription Factors Determine Cell-Type-Specific Responses to TGF-β Signaling
- (2011) Alan C. Mullen et al. CELL
- A Poised Chromatin Platform for TGF-β Access to Master Regulators
- (2011) Qiaoran Xi et al. CELL
- Lineage Regulators Direct BMP and Wnt Pathways to Cell-Specific Programs during Differentiation and Regeneration
- (2011) Eirini Trompouki et al. CELL
- Non-Smad signaling pathways
- (2011) Yabing Mu et al. CELL AND TISSUE RESEARCH
- Abnormalities in the Enamel in Bmp2-Deficient Mice
- (2011) Junsheng Feng et al. CELLS TISSUES ORGANS
- Exome Sequencing Identifies SMAD3 Mutations as a Cause of Familial Thoracic Aortic Aneurysm and Dissection With Intracranial and Other Arterial Aneurysms
- (2011) Ellen S. Regalado et al. CIRCULATION RESEARCH
- Cooperative activity of noggin and gremlin 1 in axial skeleton development
- (2011) D. A. Stafford et al. DEVELOPMENT
- Expression of the osteoarthritis-associated gene GDF5 is modulated epigenetically by DNA methylation
- (2011) Louise N. Reynard et al. HUMAN MOLECULAR GENETICS
- BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development
- (2011) B. Shu et al. JOURNAL OF CELL SCIENCE
- Genetics and epigenetics of osteoarthritis
- (2011) Louise N. Reynard et al. MATURITAS
- BMP3 Suppresses Osteoblast Differentiation of Bone Marrow Stromal Cells via Interaction with Acvr2b
- (2011) Shoichiro Kokabu et al. MOLECULAR ENDOCRINOLOGY
- Mutations at a single codon in Mad homology 2 domain of SMAD4 cause Myhre syndrome
- (2011) Carine Le Goff et al. NATURE GENETICS
- Expression of endogenous BMP-2 in periosteal progenitor cells is essential for bone healing
- (2010) Qun Wang et al. BONE
- Reversal of Cancer Cachexia and Muscle Wasting by ActRIIB Antagonism Leads to Prolonged Survival
- (2010) Xiaolan Zhou et al. CELL
- Early Mortality and Cardiorespiratory Failure in Patients with Fibrodysplasia Ossificans Progressiva
- (2010) Frederick S Kaplan et al. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
- Responsiveness of clonal limb bud cell lines to bone morphogenetic protein 2 reveals a sequential relationship between cartilage and bone cell phenotypes
- (2010) Vicki Rosen et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Hypertrophic chondrocytes undergo further differentiation to osteoblast-like cells and participate in the initial bone formation in developing chick embryo
- (2010) Maria Galotto et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Bone Morphogenetic Proteins and articular cartilage
- (2010) P.M. van der Kraan et al. OSTEOARTHRITIS AND CARTILAGE
- Osteoarthritis and a high-fat diet: the full 'OA syndrome' in a small animal model
- (2010) Peter M van der Kraan ARTHRITIS RESEARCH & THERAPY
- Purification, crystallization and preliminary data analysis of ligand–receptor complexes of growth and differentiation factor 5 (GDF5) and BMP receptor IB (BRIB)
- (2009) Alexander Kotzsch et al. Acta Crystallographica Section F-Structural Biology and Crystallization Communications
- Duplications Involving a Conserved Regulatory Element Downstream of BMP2 Are Associated with Brachydactyly Type A2
- (2009) Katarina Dathe et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Emergence, development and diversification of the TGF-β signalling pathway within the animal kingdom
- (2009) Lukasz Huminiecki et al. BMC EVOLUTIONARY BIOLOGY
- BMP2 signaling in bone development and repair
- (2009) Vicki Rosen CYTOKINE & GROWTH FACTOR REVIEWS
- Informatics approaches to understanding TGF pathway regulation
- (2009) P. Kahlem et al. DEVELOPMENT
- The regulation of TGF signal transduction
- (2009) A. Moustakas et al. DEVELOPMENT
- BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation
- (2009) K. N. Retting et al. DEVELOPMENT
- Mutation of the bone morphogenetic protein GDF3 causes ocular and skeletal anomalies
- (2009) M. Ye et al. HUMAN MOLECULAR GENETICS
- Vertebrate limb bud development: moving towards integrative analysis of organogenesis
- (2009) Rolf Zeller et al. NATURE REVIEWS GENETICS
- Mutations in GDF5 Reveal a Key Residue Mediating BMP Inhibition by NOGGIN
- (2009) Petra Seemann et al. PLoS Genetics
- Compound heterozygosity for GDF5 in Du Pan type chondrodysplasia
- (2008) Sofia Douzgou et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Lifetime risk of symptomatic knee osteoarthritis
- (2008) Louise Murphy et al. ARTHRITIS AND RHEUMATISM
- Regulation of TGF-β family signaling by E3 ubiquitin ligases
- (2008) Yasumichi Inoue et al. CANCER SCIENCE
- Bone Morphogenetic Protein-9 Is a Circulating Vascular Quiescence Factor
- (2008) Laurent David et al. CIRCULATION RESEARCH
- A Perspective: Engineering Periosteum for Structural Bone Graft Healing
- (2008) Xinping Zhang et al. CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
- A distinct cohort of progenitor cells participates in synovial joint and articular cartilage formation during mouse limb skeletogenesis
- (2008) Eiki Koyama et al. DEVELOPMENTAL BIOLOGY
- GDF3 is a BMP inhibitor that can activate Nodal signaling only at very high doses
- (2008) Ariel J. Levine et al. DEVELOPMENTAL BIOLOGY
- BMP4 Is Dispensable for Skeletogenesis and Fracture-Healing in the Limb
- (2008) Kunikazu Tsuji et al. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
- Skeletal Cell Fate Decisions Within Periosteum and Bone Marrow During Bone Regeneration
- (2008) Céline Colnot JOURNAL OF BONE AND MINERAL RESEARCH
- Cooperative Assembly of TGF-β Superfamily Signaling Complexes Is Mediated by Two Disparate Mechanisms and Distinct Modes of Receptor Binding
- (2008) Jay Groppe et al. MOLECULAR CELL
- Common variants in the GDF5-UQCC region are associated with variation in human height
- (2008) Serena Sanna et al. NATURE GENETICS
- Phylogeny.fr: robust phylogenetic analysis for the non-specialist
- (2008) A. Dereeper et al. NUCLEIC ACIDS RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started