Activin receptor type 2A (ACVR2A) functions directly in osteoblasts as a negative regulator of bone mass

Transforming Growth Factor-β Family Ligands Can Function as Antagonists by Competing for Type II Receptor Binding

(2016) Senem Aykul et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of BMPR2 leads to high bone mass due to increased osteoblast activity

(2015) J. W. Lowery et al.   JOURNAL OF CELL SCIENCE

Human Cerberus Prevents Nodal-Receptor Binding, Inhibits Nodal Signaling, and Suppresses Nodal-Mediated Phenotypes

(2015) Senem Aykul et al.   PLoS One

A myostatin and activin decoy receptor enhances bone formation in mice

(2013) P. Bialek et al.   BONE

Bone and Skeletal Muscle: Neighbors With Close Ties

(2013) Douglas J DiGirolamo et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Cell-type specific modulation of pituitary cells by activin, inhibin and follistatin

(2012) Louise M. Bilezikjian et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Role of satellite cells versus myofibers in muscle hypertrophy induced by inhibition of the myostatin/activin signaling pathway

(2012) S.-J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A soluble activin receptor Type IIA fusion protein (ACE-011) increases bone mass via a dual anabolic-antiresorptive effect in Cynomolgus monkeys

(2010) Sutada Lotinun et al.   BONE

Low bone mass in Pompe disease

(2010) Linda E.M. van den Berg et al.   BONE

A Soluble Activin Receptor Type IIB Prevents the Effects of Androgen Deprivation on Body Composition and Bone Health

(2010) Alan Koncarevic et al.   ENDOCRINOLOGY

Appendicular skeletal muscle mass is the strongest independent factor associated with femoral neck bone mineral density in adult and older men

(2010) Hubert Blain et al.   EXPERIMENTAL GERONTOLOGY

Administration of a soluble activin type IIB receptor promotes skeletal muscle growth independent of fiber type

(2010) Samuel M. Cadena et al.   JOURNAL OF APPLIED PHYSIOLOGY

Characterization of the Ligand Binding Functionality of the Extracellular Domain of Activin Receptor Type IIB

(2010) Dianne Sako et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee

(2010) A. Michael Parfitt et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

(2010) Mary L Bouxsein et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Association Between Lean Mass and Handgrip Strength With Bone Mineral Density in Physically Active Postmenopausal Women

(2010) Rosangela Villa Marin et al.   JOURNAL OF CLINICAL DENSITOMETRY

Treatment with a soluble receptor for activin improves bone mass and structure in the axial and appendicular skeleton of female cynomolgus macaques (Macaca fascicularis)

(2009) Roberto José Fajardo et al.   BONE

Single-Dose, Randomized, Double-Blind, Placebo-Controlled Study of ACE-011 (ActRIIA-IgG1) in Postmenopausal Women*

(2008) Jon Ruckle et al.   JOURNAL OF BONE AND MINERAL RESEARCH

A soluble activin Type IIA receptor induces bone formation and improves skeletal integrity

(2008) R. S. Pearsall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA