Structural studies of the TGF-βs and their receptors - insights into evolution of the TGF-β superfamily

TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairs

(2011) Tao Huang et al.   EMBO JOURNAL

The T?R-I Pre-Helix Extension Is Structurally Ordered in the Unbound Form and Its Flanking Prolines Are Essential for Binding

(2011) Jorge E. Zuniga et al.   JOURNAL OF MOLECULAR BIOLOGY

Ternary Complex of Transforming Growth Factor-β1 Reveals Isoform-specific Ligand Recognition and Receptor Recruitment in the Superfamily

(2010) Sergei Radaev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting of SMAD5 links microRNA-155 to the TGF-  pathway and lymphomagenesis

(2010) D. Rai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TGF-β and fibrosis in different organs — molecular pathway imprints

(2009) Dirk Pohlers et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Intricacies of BMP receptor assembly

(2009) Joachim Nickel et al.   CYTOKINE & GROWTH FACTOR REVIEWS

The Drosophila Activin-like ligand Dawdle signals preferentially through one isoform of the Type-I receptor Baboon

(2009) Philip A. Jensen et al.   MECHANISMS OF DEVELOPMENT

The Solution Structure of BMPR-IA Reveals a Local Disorder-to-Order Transition upon BMP-2 Binding†‡

(2008) Jochen Klages et al.   BIOCHEMISTRY

TGFβ in Cancer

(2008) Joan Massagué   CELL

Transforming Growth Factor  -Induced Smad1/5 Phosphorylation in Epithelial Cells Is Mediated by Novel Receptor Complexes and Is Essential for Anchorage-Independent Growth

(2008) A. C. Daly et al.   MOLECULAR AND CELLULAR BIOLOGY

A Very Private TGF-β Receptor Embrace

(2008) Joan Massagué   MOLECULAR CELL

Cooperative Assembly of TGF-β Superfamily Signaling Complexes Is Mediated by Two Disparate Mechanisms and Distinct Modes of Receptor Binding

(2008) Jay Groppe et al.   MOLECULAR CELL

A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions

(2008) C. Grutter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA