标题
mTOR in Brain Physiology and Pathologies
作者
关键词
-
出版物
PHYSIOLOGICAL REVIEWS
Volume 95, Issue 4, Pages 1157-1187
出版商
American Physiological Society
发表日期
2015-08-13
DOI
10.1152/physrev.00038.2014
参考文献
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- STRADα deficiency results in aberrant mTORC1 signaling during corticogenesis in humans and mice
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- mTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice
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- Early Progenitor Cell Marker Expression Distinguishes Type II From Type I Focal Cortical Dysplasias
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- Rapamycin Protects against Neuron Death in In Vitro andIn Vivo Models of Parkinson's Disease
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- Nucleus Accumbens Core Mammalian Target of Rapamycin Signaling Pathway Is Critical for Cue-Induced Reinstatement of Cocaine Seeking in Rats
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- Dysregulation of mTOR Signaling in Fragile X Syndrome
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- Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice
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- Cyclic AMP Controls mTOR through Regulation of the Dynamic Interaction between Rheb and Phosphodiesterase 4D
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- The Late Endosome is Essential for mTORC1 Signaling
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- Dysregulation of the mTOR Pathway Mediates Impairment of Synaptic Plasticity in a Mouse Model of Alzheimer's Disease
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- An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1
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- RTP801 Is Induced in Parkinson's Disease and Mediates Neuron Death by Inhibiting Akt Phosphorylation/Activation
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- Inhibition of the Mammalian Target of Rapamycin Signaling Pathway Suppresses Dentate Granule Cell Axon Sprouting in a Rodent Model of Temporal Lobe Epilepsy
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- The Mammalian Target of Rapamycin Signaling Pathway Mediates Epileptogenesis in a Model of Temporal Lobe Epilepsy
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- The Rheb-mTOR Pathway Is Upregulated in Reactive Astrocytes of the Injured Spinal Cord
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- Akt Signals through the Mammalian Target of Rapamycin Pathway to Regulate CNS Myelination
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- Pharmacological Inhibition of mTORC1 Suppresses Anatomical, Cellular, and Behavioral Abnormalities in Neural-Specific Pten Knock-Out Mice
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- Beclin 1 Gene Transfer Activates Autophagy and Ameliorates the Neurodegenerative Pathology in -Synuclein Models of Parkinson's and Lewy Body Diseases
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- Metabolic control of puberty onset: New players, new mechanisms
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- Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss
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- The Role of Hypothalamic Mammalian Target of Rapamycin Complex 1 Signaling in Diet-Induced Obesity
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- Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease
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- Response of a Neuronal Model of Tuberous Sclerosis to Mammalian Target of Rapamycin (mTOR) Inhibitors: Effects on mTORC1 and Akt Signaling Lead to Improved Survival and Function
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- Homer Interactions Are Necessary for Metabotropic Glutamate Receptor-Induced Long-Term Depression and Translational Activation
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- Sirolimus Is Associated with New-Onset Diabetes in Kidney Transplant Recipients
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- Mammalian target of rapamycin (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin
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- AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
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- Reversal of learning deficits in a Tsc2 +/− mouse model of tuberous sclerosis
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- PTEN signaling in brain: neuropathology and tumorigenesis
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- Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway
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