Transient and rapid activation of Akt/GSK-3β and mTORC1 signaling by D3 dopamine receptor stimulation in dorsal striatum and nucleus accumbens

A unifying model for mTORC1-mediated regulation of mRNA translation

(2012) Carson C. Thoreen et al.   NATURE

Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy

(2012) Mark J. Millan et al.   NATURE REVIEWS DRUG DISCOVERY

Blockade of dopamine D3 but not D2 receptors reverses the novel object discrimination impairment produced by post-weaning social isolation: implications for schizophrenia and its treatment

(2011) David J. G. Watson et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Pre-synaptic dopamine D3 receptor mediates cocaine-induced structural plasticity in mesencephalic dopaminergic neurons via ERK and Akt pathways

(2011) Ginetta Collo et al.   JOURNAL OF NEUROCHEMISTRY

Haloperidol Regulates the State of Phosphorylation of Ribosomal Protein S6 via Activation of PKA and Phosphorylation of DARPP-32

(2011) Emmanuel Valjent et al.   NEUROPSYCHOPHARMACOLOGY

Selective Blockade of Dopamine D3 Receptors Enhances while D2 Receptor Antagonism Impairs Social Novelty Discrimination and Novel Object Recognition in Rats: A Key Role for the Prefrontal Cortex

(2011) David JG Watson et al.   NEUROPSYCHOPHARMACOLOGY

Selective pharmacogenetic inhibition of mammalian target of Rapamycin complex I (mTORC1) blocks long-term synaptic plasticity and memory storage

(2011) Loredana Stoica et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beyond cAMP: the regulation of Akt and GSK3 by dopamine receptors

(2011) Jean-Martin Beaulieu   Frontiers in Molecular Neuroscience

Current perspectives on selective dopamine D3 receptor antagonists as pharmacotherapeutics for addictions and related disorders

(2010) Christian A. Heidbreder et al.   Annals of the New York Academy of Sciences

ERK in Learning and Memory: A Review of Recent Research

(2010) Sheng Peng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The dopamine D3 receptor antagonist, S33138, counters cognitive impairment in a range of rodent and primate procedures

(2010) Mark J. Millan et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Mammalian Target of Rapamycin (mTOR): Conducting the Cellular Signaling Symphony

(2010) Kathryn G. Foster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Double Dissociation of the Effects of Haloperidol and the Dopamine D3 Receptor Antagonist ABT-127 on Acquisition vs. Expression of Cocaine-Conditioned Activity in Rats

(2010) T. J. Banasikowski et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Signaling Pathways Leading to Phosphorylation of Akt and GSK-3  by Activation of Cloned Human and Rat Cerebral D2 and D3 Receptors

(2010) C. Mannoury la Cour et al.   MOLECULAR PHARMACOLOGY

Inhibition of the mammalian target of rapamycin pathway by rapamycin blocks cocaine-induced locomotor sensitization

(2010) J. Wu et al.   NEUROSCIENCE

What is the degree of segregation between striatonigral and striatopallidal projections?

(2010) Jesus Bertran-Gonzalez   Frontiers in Neuroanatomy

Mammalian target of rapamycin complex 1-mediated phosphorylation of eukaryotic initiation factor 4E-binding protein 1 requires multiple protein–protein interactions for substrate recognition

(2009) Elaine A. Dunlop et al.   CELLULAR SIGNALLING

Identification of cAMP-Dependent Kinase as a Third in Vivo Ribosomal Protein S6 Kinase in Pancreatic β-Cells

(2009) Claire E.J. Moore et al.   JOURNAL OF MOLECULAR BIOLOGY

The D3dopamine receptor inhibits dopamine release in PC-12/hD3 cells by autoreceptor signaling via PP-2B, CK1, and Cdk-5

(2009) Pei-Chun Chen et al.   JOURNAL OF NEUROCHEMISTRY

Striatal Medium-Sized Spiny Neurons: Identification by Nuclear Staining and Study of Neuronal Subpopulations in BAC Transgenic Mice

(2009) Miriam Matamales et al.   PLoS One

Looking BAC at striatal signaling: cell-specific analysis in new transgenic mice

(2009) Emmanuel Valjent et al.   TRENDS IN NEUROSCIENCES

mTOR signaling: At the crossroads of plasticity, memory and disease

(2009) Charles A. Hoeffer et al.   TRENDS IN NEUROSCIENCES

Oncogenic MAPK Signaling Stimulates mTORC1 Activity by Promoting RSK-Mediated Raptor Phosphorylation

(2008) Audrey Carrière et al.   CURRENT BIOLOGY

Chronic activation of the D2 dopamine autoreceptor inhibits synaptogenesis in mesencephalic dopaminergic neuronsin vitro

(2008) C. Fasano et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Opposing Patterns of Signaling Activation in Dopamine D1 and D2 Receptor-Expressing Striatal Neurons in Response to Cocaine and Haloperidol

(2008) J. Bertran-Gonzalez et al.   JOURNAL OF NEUROSCIENCE

Cell type–specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs

(2008) Helen S Bateup et al.   NATURE NEUROSCIENCE

Cognitive Impairment in Schizophrenia: a Review of Developmental and Genetic Models, and Pro-cognitive Profile of the Optimised D3 > D2 Antagonist, S33138

(2008) Mark J. Millan et al.   THERAPIE

On the participation of mTOR in recognition memory

(2007) Jociane C. Myskiw et al.   NEUROBIOLOGY OF LEARNING AND MEMORY