Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models

Akt Suppresses Retrograde Degeneration of Dopaminergic Axons by Inhibition of Macroautophagy

(2011) H.-C. Cheng et al.   JOURNAL OF NEUROSCIENCE

Nucleolar Disruption in Dopaminergic Neurons Leads to Oxidative Damage and Parkinsonism through Repression of Mammalian Target of Rapamycin Signaling

(2011) C. Rieker et al.   JOURNAL OF NEUROSCIENCE

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

(2010) Noriyuki Matsuda et al.   JOURNAL OF CELL BIOLOGY

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

(2010) Sven Geisler et al.   NATURE CELL BIOLOGY

Genetic Animal Models of Parkinson's Disease

(2010) Ted M. Dawson et al.   NEURON

Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

(2010) Patricia Spilman et al.   PLoS One

Preservation of GABA A Receptor Function by PTEN Inhibition Protects Against Neuronal Death in Ischemic Stroke

(2010) Baosong Liu et al.   STROKE

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Pitx3 potentiates Nurr1 in dopamine neuron terminal differentiation through release of SMRT-mediated repression

(2009) F. M. J. Jacobs et al.   DEVELOPMENT

Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development

(2009) Wei Lin et al.   DEVELOPMENTAL BIOLOGY

Arm swing magnitude and asymmetry during gait in the early stages of Parkinson's disease

(2009) Michael D. Lewek et al.   GAIT & POSTURE

Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF- B signaling

(2009) D. Sha et al.   HUMAN MOLECULAR GENETICS

Nurr1 Is Required for Maintenance of Maturing and Adult Midbrain Dopamine Neurons

(2009) B. Kadkhodaei et al.   JOURNAL OF NEUROSCIENCE

Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss

(2009) Luke S Tain et al.   NATURE NEUROSCIENCE

Tests to assess motor phenotype in mice: a user's guide

(2009) Simon P. Brooks et al.   NATURE REVIEWS NEUROSCIENCE

The MitoPark Mouse – An animal model of Parkinson's disease with impaired respiratory chain function in dopamine neurons

(2009) Mats I. Ekstrand et al.   PARKINSONISM & RELATED DISORDERS

Selective Deletion of PTEN in Dopamine Neurons Leads to Trophic Effects and Adaptation of Striatal Medium Spiny Projecting Neurons

(2009) Oscar Diaz-Ruiz et al.   PLoS One

Parkinson’s disease: genetic versus toxin-induced rodent models

(2008) Mügen Terzioglu et al.   FEBS Journal

Activation of an Endogenous Suicide Response after Perturbation of rRNA Synthesis Leads to Neurodegeneration in Mice

(2008) R. Parlato et al.   JOURNAL OF NEUROSCIENCE

Decreased NURR1 gene expression in patients with Parkinson's disease

(2008) Weidong Le et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Glutamate Receptors on Dopamine Neurons Control the Persistence of Cocaine Seeking

(2008) David Engblom et al.   NEURON

Phosphatase and tensin homolog, deleted on chromosome 10 deficiency in brain causes defects in synaptic structure, transmission and plasticity, and myelination abnormalities

(2007) M.M. Fraser et al.   NEUROSCIENCE