Chromosomal instability, aneuploidy and routine high-resolution DNA content analysis in oral cancer risk evaluation

Overexpression of the DNA sensor proteins, absent in melanoma 2 and interferon-inducible 16, contributes to tumorigenesis of oral squamous cell carcinoma with p53 inactivation

(2012) Yuudai Kondo et al.   CANCER SCIENCE

Losing balance: the origin and impact of aneuploidy in cancer

(2012) Andrew J Holland et al.   EMBO REPORTS

Chromosomal instability and aneuploidy in cancer: from yeast to man

(2012) Sarah J Pfau et al.   EMBO REPORTS

Cancer chromosomal instability: therapeutic and diagnostic challenges

(2012) Nicholas McGranahan et al.   EMBO REPORTS

DNA ploidy measurement in oral leukoplakia: Different results between flow and image cytometry

(2012) E.R.E.A. Brouns et al.   ORAL ONCOLOGY

Chromosomal aberrations and aneuploidy in oral potentially malignant lesions: distinctive features for tongue

(2011) Patrizio Castagnola et al.   BMC CANCER

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Mad2 Is a Critical Mediator of the Chromosome Instability Observed upon Rb and p53 Pathway Inhibition

(2011) Juan-Manuel Schvartzman et al.   CANCER CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Aurora B hyperactivation by Bub1 overexpression promotes chromosome missegregation

(2011) Robin M. Ricke et al.   CELL CYCLE

Two Distinct Routes to Oral Cancer Differing in Genome Instability and Risk for Cervical Node Metastasis

(2011) A. Bhattacharya et al.   CLINICAL CANCER RESEARCH

Probing thein vivofunction of Mad1:C-Mad2 in the spindle assembly checkpoint

(2011) Luca L Fava et al.   EMBO JOURNAL

CCND1 amplification and protein overexpression in oral squamous cell carcinoma of young patients

(2011) Estela Kaminagakura et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation

(2011) Robin M. Ricke et al.   JOURNAL OF CELL BIOLOGY

Field effect in oral precancer as assessed by DNA flow cytometry and array-CGH

(2011) Monica Pentenero et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Bub1 and BubR1: at the Interface between Chromosome Attachment and the Spindle Checkpoint

(2011) S. Elowe   MOLECULAR AND CELLULAR BIOLOGY

Prognostic value of DNA ploidy status in patients with oral leukoplakia

(2011) Jantine F. Bremmer et al.   ORAL ONCOLOGY

Advances and applications of oral cancer basic research

(2011) Sabrina Daniela da Silva et al.   ORAL ONCOLOGY

Aneuploidy Drives a Mutator Phenotype in Cancer

(2011) R. D. Kolodner et al.   SCIENCE

Aneuploidy Drives Genomic Instability in Yeast

(2011) J. M. Sheltzer et al.   SCIENCE

Mutational Inactivation of STAG2 Causes Aneuploidy in Human Cancer

(2011) D. A. Solomon et al.   SCIENCE

Oral Dysplasia: Biomarkers, Treatment, and Follow-up

(2011) Paul Nankivell et al.   Current Oncology Reports

Genomic aberrations in normal appearing mucosa fields distal from oral potentially malignant lesions

(2011) W. Giaretti et al.   CELLULAR ONCOLOGY

S-phase fraction and DNA ploidy in oral leukoplakia

(2010) Rahul Khanna et al.   ANZ JOURNAL OF SURGERY

Abnormal DNA content in oral epithelial dysplasia is associated with increased risk of progression to carcinoma

(2010) G Bradley et al.   BRITISH JOURNAL OF CANCER

A rapid and optimization-free procedure allows the in vivo detection of subtle cell cycle and ploidy alterations in tissues by flow cytometry

(2010) Christina Heinlein et al.   CELL CYCLE

Mechanisms of Chromosomal Instability

(2010) Sarah L. Thompson et al.   CURRENT BIOLOGY

Breast cancer genomes—form and function

(2010) James Korkola et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Simultaneous assessment of DNA ploidy and biomarker expression in paraffin-embedded tissue sections

(2010) Stijn J H M Fleskens et al.   HISTOPATHOLOGY

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

(2010) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Comparative evaluation of genetic assays to identify oral pre-cancerous fields

(2010) Jantine F. Bremmer et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Oral epithelial dysplasia classification systems: predictive value, utility, weaknesses and scope for improvement

(2010) S. Warnakulasuriya et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Oral potentially malignant lesions: first-level micro-histological diagnosis from tissue fragments sampled in liquid-based diagnostic cytology

(2010) Roberto Navone et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Genomic instability — an evolving hallmark of cancer

(2010) Simona Negrini et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mutational analyses of the BRAF, KRAS, and PIK3CA genes in oral squamous cell carcinoma

(2010) Karl C. Bruckman et al.   ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS

CXCL12/SDF‐1α Activates NF‐κB and Promotes Oral Cancer Invasion through the Carma3/Bcl10/Malt1 Complex

(2010) Aasia O Rehman et al.   International Journal of Oral Science

Screening for Oral Precancer with Noninvasive Genetic Cytology

(2009) J. F. Bremmer et al.   Cancer Prevention Research

Functional Genomic Analysis Identified Epidermal Growth Factor Receptor Activation as the Most Common Genetic Event in Oral Squamous Cell Carcinoma

(2009) J. J.-C. Sheu et al.   CANCER RESEARCH

Telomeres and telomerase in cancer

(2009) S. E. Artandi et al.   CARCINOGENESIS

Road to the crossroads of life and death: Linking sister chromatid cohesion and separation to aneuploidy, apoptosis and cancer

(2009) Anil K. Panigrahi et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Chromosomal instability and cancer: not just one CINgle mechanism

(2009) C R. Boland et al.   GUT

Identification of a microRNA signature associated with progression of leukoplakia to oral carcinoma

(2009) Nilva K. Cervigne et al.   HUMAN MOLECULAR GENETICS

Molecular markers in oral epithelial dysplasia: review

(2009) Gayani Pitiyage et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

(2009) Andrew J. Holland et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

DNA aneuploidy and dysplasia in oral potentially malignant disorders: Association with cigarette smoking and site

(2009) Monica Pentenero et al.   ORAL ONCOLOGY

p16 Promoter Methylation Is a Potential Predictor of Malignant Transformation in Oral Epithelial Dysplasia

(2008) G. L. Hall et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Ulcerative Colitis Is a Disease of Accelerated Colon Aging: Evidence From Telomere Attrition and DNA Damage

(2008) Rosa Ana Risques et al.   GASTROENTEROLOGY

Aneuploidy: Cells Losing Their Balance

(2008) Eduardo M. Torres et al.   GENETICS

Examining the link between chromosomal instability and aneuploidy in human cells

(2008) Sarah L. Thompson et al.   JOURNAL OF CELL BIOLOGY

Genome stability is ensured by temporal control of kinetochore–microtubule dynamics

(2008) Samuel F. Bakhoum et al.   NATURE CELL BIOLOGY

DNA ploidy analysis by image cytometry helps to identify oral epithelial dysplasias with a high risk of malignant progression

(2008) A. Torres-Rendon et al.   ORAL ONCOLOGY

Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers

(2008) T. D. Barber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The global burden of urinary bladder cancer

(2008) D. Maxwell Parkin   SCANDINAVIAN JOURNAL OF UROLOGY AND NEPHROLOGY

Aneuploidy Affects Proliferation and Spontaneous Immortalization in Mammalian Cells

(2008) B. R. Williams et al.   SCIENCE

Defining ‘chromosomal instability’

(2008) Jochen B. Geigl et al.   TRENDS IN GENETICS

Chromosomal imbalances in oral squamous cell carcinoma: Examination of 31 cell lines and review of the literature

(2007) Christa Lese Martin et al.   ORAL ONCOLOGY