4.7 Article

Gamma irradiation as an alternative treatment to abolish allergenicity of lectins in food

Journal

FOOD CHEMISTRY
Volume 124, Issue 4, Pages 1289-1295

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.foodchem.2010.07.098

Keywords

Food irradiation; Lectins; Food allergen; bis-ANS; Misfolded states

Funding

  1. Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
  2. Ministerio da Ciencia e Tecnologia (Brazilian)
  3. Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)

Ask authors/readers for more resources

Food irradiation is the process of exposing food to ionising radiation to eliminate microorganisms or insects. Lectins are the most common agents in food intolerance, and efficient methods to reduce unwanted or intolerant immunological effects of lectins have not yet been described. Sebastiania jacobinensis bark lectin was structurally altered after gamma irradiation. Hemagglutination assays showed that the lectin was stimulated by low doses of radiation (0.1 kGy), while high doses (above 1 kGy) induced a significant loss of activity. The effect of gamma-radiation on lectin hydrophobicity was measured by intrinsic and bis-ANS fluorescence. High doses of ionising radiation suppressed the intrinsic fluorescence emission and promoted polypeptide fragmentation and hydrophobic surface modification. The results suggested that changes in the hydrophobic surface induced by gamma irradiation led to protein misfolding and, subsequently, to aggregation. The pioneering viewpoints presented on the stability of a food allergen after gamma irradiation might contribute to the development of harmless and more effective methods to reduce or eliminate food allergenicity. (C) 2010 Elsevier Ltd. All rights reserved.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Biotechnology & Applied Microbiology

The green microalgae Tetradesmus obliquus (Scenedesmus acutus) as lectin source in the recognition of ABO blood type: purification and characterization

A. J. Silva, V. L. R. Cavalcanti, A. L. F. Porto, W. A. Gama, R. M. P. Brandao-Costa, Raquel Pedrosa Bezerra

JOURNAL OF APPLIED PHYCOLOGY (2020)

Article Biochemistry & Molecular Biology

FDS, a novel saponin isolated from Felicium decipiens: Lectin interaction and biological complementary activities

Romero M. P. Brandao-Costa, Thiago Pajeu Nascimento, Raquel Pedrosa Bezerra, Ana L. F. Porto

PROCESS BIOCHEMISTRY (2020)

Article Biology

Ultrasound-Assisted Enzyme-Catalyzed Hydrolysis of Collagen to Produce Peptides With Biomedical Potential: Collagenase From Aspergillus terreus UCP1276

Romualdo B. Costa-Junior, Romero M. P. Brandao-Costa, Wendell W. C. Albuquerque, Juanize M. S. Batista, Raquel B. Pedrosa, Ana L. F. Porto

BIOELECTROMAGNETICS (2020)

Article Biochemical Research Methods

Purification of a lectin from Cratylia mollis crude extract seed by a single step PEG/phosphate aqueous two-phase system

Cynthia Oliveira Nascimento, Romero Marcos Pedrosa Brandao Costa, Paulo Antonio Soares, Polyanna Nunes Herculano, Tatiana Souza Porto, Thiago Pajeu Nascimento, Carolina de Albuquerque Lima, Raquel Pedrosa Bezerra, Jose Antonio Teixeira, Luana Cassandra Breitenbach Barroso Coelho, Maria Tereza dos Santos Correia, Maria das Gracas Carneiro-da-Cunha, Ana Lucia Figueiredo Porto

PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY (2020)

Article Agriculture, Dairy & Animal Science

Factors affecting occurrence of demodecosis byDemodex bovisin Sindhi cattle (Bos indicus)

Jose Nerivaldo de Araujo Wanderley, Ana Celia Rodrigues Athayde, Jose Fabio Paulino de Moura, Leilson Rocha Bezerra, Antonio Fernando de Melo Vaz, Ednaldo Queiroga de Lima, Juliana Paula Felipe de Oliveira, Wilson Wouflan Silva

TROPICAL ANIMAL HEALTH AND PRODUCTION (2020)

Article Plant Sciences

Bioprospection of Libidibia ferrea var . ferrea : Phytochemical properties and antibacterial activity

M. S. M. Luna, R. A. de Paula, R. M. P. Brandao Costa, J. dos Anjos, M. da Silva, M. T. S. Correia

SOUTH AFRICAN JOURNAL OF BOTANY (2020)

Article Biochemistry & Molecular Biology

Fibrinolytic enzyme from Arthrospira platensis cultivated in medium culture supplemented with corn steep liquor

Priscila Danielly Santos de Barros, Pablo Eugenio Costa e Silva, Thiago Pajeu Nascimento, Romero Marcos Pedrosa Brandao Costa, Raquel Pedrosa Bezerra, Ana Lucia Figueiredo Porto

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Veterinary Sciences

Continuous intravenous anesthesia with racemic ketamine or dextroketamine and detomidine in female dogs

F. Henrique, S. A. R. S. Pereira, L. F. Batista, L. H. Oliveira, N. M. O. Monteiro, R. N. Parentoni, A. P. Souza, A. F. M. Vaz, P. Nobrega Neto

Summary: The combination of ketamine and detomidine or dextrocetamine with continuous infusion of detomidine in female dogs resulted in similar cardiorespiratory effects and anesthetic outcomes, with observed changes in heart rate, blood pressure, respiratory rate, and ECG parameters during the study.

ARQUIVO BRASILEIRO DE MEDICINA VETERINARIA E ZOOTECNIA (2021)

Article Veterinary Sciences

Nelore females along a new Brazilian agricultural frontier: hematological and clinical-biochemical approaches

L. H. O. Tolentino, M. L. D. L. Tolentino, J. B. . Dantas, S. S. . Fonseca, A. F. M. Vaz

Summary: This study aimed to determine the hematological and biochemical reference intervals of healthy Nelore matrices raised in the southwest of Piaui state in Brazil. The findings showed that Nelore females have slightly different biochemical and hematological profiles compared to other breeds, possibly due to environmental and nutritional factors specific to the region.

ARQUIVO BRASILEIRO DE MEDICINA VETERINARIA E ZOOTECNIA (2021)

Article Polymer Science

Polymeric Microparticles of Calcium Pectinate Containing Urea for Slow Release in Ruminant Diet

Myrla Melo, Andre Da Silva, Edson Silva Filho, Ronaldo Oliveira, Jarbas Silva Junior, Juliana Paula Oliveira, Antonio Vaz, Jose Moura, Jose Pereira Filho, Leilson Bezerra

Summary: Microencapsulated urea formulations with different urea concentrations were used in ruminant feeding to control the release rate of ammonia in the rumen, improving nitrogen utilization and reducing the risk of ruminant intoxication. The degradation kinetics demonstrated that controlled release from microencapsulated systems significantly decreased the release rate compared to free urea. Additionally, blood serum concentrations of certain metabolites were higher in sheep receiving microencapsulated urea, with the MPec2 system being recommended for its more controlled core release.

POLYMERS (2021)

Review Veterinary Sciences

Anthelmintic intoxication in goats and sheep: A systematic review

C. C. Oliveira, D. F. L. Costa, C. H. Limeira, D. B. Nogueira, B. H. R. Nascimento, A. F. M. Vaz

Summary: The objective of this study was to conduct research on anthelmintic intoxication in sheep and goats by analyzing literature available in electronic media. A total of 28 articles were included in the systematic review, indicating the presence of multiple drugs and symptoms in cases of anthelmintic intoxication. The study highlights the importance of cautious use of antiparasitic drugs in preventing intoxication.

RESEARCH IN VETERINARY SCIENCE (2022)

Article Agronomy

Prednisolone associated with doxycycline on the hematological parameters and serum proteinogram of dogs with ehrlichiosis

Ariana de Castro Tavares da Silva, Jose Romulo Soares dos Santos, Rosangela Maria Nunes da Silva, Vanessa Lira de Santana, Francisco Savio de Moura Martins, Brunna Muniz Rodrigues Falcao, Atticcus Tanikawa, Talles Monte de Almeida, Antonio Fernando de Melo Vaz, Almir Pereira de Souza

Summary: This study assessed the treatment of dogs with ehrlichiosis using doxycycline hydrochloride and/or prednisolone. The results showed that both therapeutic protocols resulted in improvement in hematological parameters and protein profile with similar effects.

CIENCIA RURAL (2021)

Article Biotechnology & Applied Microbiology

Biotechnological potential of a novel tannase-acyl hydrolase from Aspergillus sydowii using waste coir residue: Aqueous two-phase system and chromatographic techniques

Katia K. S. A. Albuquerque, Wendell W. C. Albuquerque, Romero M. P. B. Costa, Juanize Matias S. Batista, Daniela A. Marques, Raquel Pedrosa Bezerra, Polyanna N. Herculano, Ana L. F. Porto

BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY (2020)

Article Multidisciplinary Sciences

Protease from Mucor subtilissimus UCP 1262: Evaluation of several specific protease activities and purification of a fibrinolytic enzyme

Thiago P. Nascimento, Amanda Emmanuelle S. Conniff, JosE Arion S. Moura, Juanize Matias S. Batista, Romero Marcos P. B. Costa, Camila S. Porto, Galba Maria C. Takaki, Tatiana S. Porto, Ana LUcia F. Porto

ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS (2020)

Article Parasitology

High seroprevalence and associated factors for visceral leishmaniasis in dogs in a transmission area of Paraiba state, Northeastern Brazil

Maria das Gracas da Silva Bernardino, Debora Ferreira do Santos Angelo, Raizza Barros Sousa Silva, Edijanio Galdino da Silva, Laysa Freire Franco e Silva, Antonio Fernando de Melo Vaz, Marcia Almeida de Melo, Carolina de Sousa Americo Batista Santos, Clebert Jose Alves, Sergio Santos de Azevedo

REVISTA BRASILEIRA DE PARASITOLOGIA VETERINARIA (2020)

Article Chemistry, Applied

The first harmonised total diet study in Portugal: Vitamin D occurrence and intake assessment

M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira

Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.

FOOD CHEMISTRY (2024)

Article Chemistry, Applied

The digestion fates of lipids with different unsaturated levels in people with different age groups

Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu

Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.

FOOD CHEMISTRY (2024)

Article Chemistry, Applied

Fabrication and characterization of chitosan-pectin emulsion-filled hydrogel prepared by cold-set gelation to improve bioaccessibility of lipophilic bioactive compounds

Hyunjong Yu, Huisu Kim, Pahn-Shick Chang

Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.

FOOD CHEMISTRY (2024)

Article Chemistry, Applied

The effect of lactic acid bacteria fermentation on physicochemical properties of starch from fermented proso millet flour

Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke

Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.

FOOD CHEMISTRY (2024)

Article Chemistry, Applied

Novel competitive electrochemical impedance biosensor for the ultrasensitive detection of umami substances based on Pd/Cu-TCPP(Fe)

Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu

Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.

FOOD CHEMISTRY (2024)

Article Chemistry, Applied

Identification and comparison of milk fat globule membrane and whey proteins from Selle Français, Welsh pony, and Tieling Draft horse mare's milk

Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang

Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.

FOOD CHEMISTRY (2024)

Article Chemistry, Applied

Phenols and saliva effect on virgin olive oil aroma release: A chemical and sensory approach

Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales

Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.

FOOD CHEMISTRY (2024)

Article Chemistry, Applied

Preparation and properties of pH-sensitive cationic starch nanoparticles

Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen

Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.

FOOD CHEMISTRY (2024)

Article Chemistry, Applied

Direct seeding compromised the vitamin C content of baby vegetables and the glucosinolate content of mature vegetables in Asian leafy brassicas

Andrea Koo, Vinayak Ghate, Weibiao Zhou

Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.

FOOD CHEMISTRY (2024)

Article Chemistry, Applied

ACE inhibitory peptides from enzymatic hydrolysate of fermented black sesame seed: Random forest-based optimization, screening, and molecular docking analysis

Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie

Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.

FOOD CHEMISTRY (2024)

Article Chemistry, Applied

Exploration of digestion-resistant immunodominant epitopes in shrimp (Penaeus vannamei) allergens

Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun

Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.

FOOD CHEMISTRY (2024)

Article Chemistry, Applied

Effect of milling on in vitro Digestion-Induced release and bioaccessibility of active compounds in rice

Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan

Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.

FOOD CHEMISTRY (2024)

Article Chemistry, Applied

Unraveling proteome changes of Sunit lamb meat in different feeding regimes and its relationship to flavor analyzed by TMT-labeled quantitative proteomic

Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin

Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.

FOOD CHEMISTRY (2024)

Article Chemistry, Applied

Mechanism of aroma enhancement methods in accelerating Congou black tea acidification subjected to room temperature storage

Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni

Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.

FOOD CHEMISTRY (2024)

Article Chemistry, Applied

Immobilizing amyloglucosidase on inorganic hybrid nanoflowers to prepare time-temperature integrators for chilled pork quality monitoring

Lin Wang, Falai Ma, Zihan Li, Yan Zhang

Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.

FOOD CHEMISTRY (2024)