The role of dead cell clearance in the etiology and pathogenesis of systemic lupus erythematosus: dendritic cells as potential targets

Apoptotic Cells Protect Mice against Lipopolysaccharide-Induced Shock

(2014) Y. Ren et al.   JOURNAL OF IMMUNOLOGY

Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines

(2014) Christine Schauer et al.   NATURE MEDICINE

Breaking Immunological Tolerance in Systemic Lupus Erythematosus

(2014) Elmar Pieterse et al.   Frontiers in Immunology

Toll-like Receptor 2 Is Required for Autoantibody Production and Development of Renal Disease in Pristane-Induced Lupus

(2013) Vilma Urbonaviciute et al.   ARTHRITIS AND RHEUMATISM

A novel antagonist of Toll-like receptors 7, 8 and 9 suppresses lupus disease-associated parameters in NZBW/F1 mice

(2013) Fu-Gang Zhu et al.   AUTOIMMUNITY

Milk fat globule-EGF factor 8 mediates the enhancement of apoptotic cell clearance by glucocorticoids

(2013) K Lauber et al.   CELL DEATH AND DIFFERENTIATION

Unknown

(2013) Natalya Seredkina et al.   MOLECULAR MEDICINE

Cooperative binding of Annexin A5 to phosphatidylserine on apoptotic cell membranes

(2013) Christina Janko et al.   PHYSICAL BIOLOGY

Surface code—biophysical signals for apoptotic cell clearance

(2013) Mona Biermann et al.   PHYSICAL BIOLOGY

Safety and pharmacodynamics of rontalizumab in patients with systemic lupus erythematosus: Results of a phase I, placebo-controlled, double-blind, dose-escalation study

(2012) Jacqueline M. McBride et al.   ARTHRITIS AND RHEUMATISM

Down-regulation of interferon signature in systemic lupus erythematosus patients by active immunization with interferon α-kinoid

(2012) Bernard R. Lauwerys et al.   ARTHRITIS AND RHEUMATISM

Immunity and autoimmunity to dsDNA and chromatin – the role of immunogenic DNA-binding proteins and nuclease deficiencies

(2012) Ole Petter Rekvig et al.   AUTOIMMUNITY

Colourful death: Six-parameter classification of cell death by flow cytometry—Dead cells tell tales

(2012) Luis E. Munoz et al.   AUTOIMMUNITY

The role of somatic hypermutation in the generation of pathogenic antibodies in SLE

(2012) Kristin Schroeder et al.   AUTOIMMUNITY

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

The evolution of the danger theory

(2012) Polly Matzinger   Expert Review of Clinical Immunology

Autoantibodies against galectins are associated with antiphospholipid syndrome in patients with systemic lupus erythematosus

(2012) K. Sarter et al.   GLYCOBIOLOGY

12/15-Lipoxygenase Orchestrates the Clearance of Apoptotic Cells and Maintains Immunologic Tolerance

(2012) Stefan Uderhardt et al.   IMMUNITY

Apoptotic-cell-derived membrane vesicles induce an alternative maturation of human dendritic cells which is disturbed in SLE

(2012) Eva-Marie Fehr et al.   JOURNAL OF AUTOIMMUNITY

Review: apoptotic mechanisms in bacterial infections of the central nervous system

(2012) Geetha Parthasarathy et al.   Frontiers in Immunology

Safety profile and clinical activity of sifalimumab, a fully human anti-interferon   monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study

(2011) J. T. Merrill et al.   ANNALS OF THE RHEUMATIC DISEASES

Activation-induced deaminase-deficient MRL/lpr mice secrete high levels of protective antibodies against lupus nephritis

(2011) Chuancang Jiang et al.   ARTHRITIS AND RHEUMATISM

Caspase-activated DNase is required for maintenance of tolerance to lupus nuclear autoantigens

(2011) Neelakshi R. Jog et al.   ARTHRITIS AND RHEUMATISM

Natural IgM Is Required for Suppression of Inflammatory Arthritis by Apoptotic Cells

(2011) C. A. Notley et al.   JOURNAL OF IMMUNOLOGY

Inefficient clearance of dying cells in patients with SLE: anti-dsDNA autoantibodies, MFG-E8, HMGB-1 and other players

(2010) Kristin Kruse et al.   APOPTOSIS

Dangerous attraction: phagocyte recruitment and danger signals of apoptotic and necrotic cells

(2010) Christoph Peter et al.   APOPTOSIS

IgG opsonized nuclear remnants from dead cells cause systemic inflammation in SLE

(2010) Luis E. Munoz et al.   AUTOIMMUNITY

Autoimmunity and chronic inflammation — Two clearance-related steps in the etiopathogenesis of SLE

(2010) Luis E. Muñoz et al.   AUTOIMMUNITY REVIEWS

The Classical and Regulatory Functions of C1q in Immunity and Autoimmunity

(2010) Jinhua Lu et al.   Cellular & Molecular Immunology

Necroptosis as an alternative form of programmed cell death

(2010) Dana E Christofferson et al.   CURRENT OPINION IN CELL BIOLOGY

Dendritic Cells in Systemic Lupus Erythematosus

(2010) Heather M. Seitz et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Cell death in the neighbourhood: direct microenvironmental effects of apoptosis in normal and neoplastic tissues

(2010) Christopher D Gregory et al.   JOURNAL OF PATHOLOGY

The interferon-α signature of systemic lupus erythematosus

(2010) G. Obermoser et al.   LUPUS

The role of defective clearance of apoptotic cells in systemic autoimmunity

(2010) Luis E. Muñoz et al.   Nature Reviews Rheumatology

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

(2010) A. Hakkim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Die Bedeutung einer unvollständigen Beseitigung apoptotischer Zellen für Ätiologie und Pathogenese des SLE

(2010) L.E. Muñoz et al.   ZEITSCHRIFT FUR RHEUMATOLOGIE

The role of dendritic cells in the pathogenesis of systemic lupus erythematosus

(2010) Justin H Fransen et al.   ARTHRITIS RESEARCH & THERAPY

C1q inhibits immune complex-induced interferon-α production in plasmacytoid dendritic cells: A novel link between C1q deficiency and systemic lupus erythematosus pathogenesis

(2009) Christian Lood et al.   ARTHRITIS AND RHEUMATISM

Mouse dendritic cells matured by ingestion of apoptotic blebs induce T cells to produce interleukin-17

(2009) Justin H. Fransen et al.   ARTHRITIS AND RHEUMATISM

Remnants of secondarily necrotic cells fuel inflammation in systemic lupus erythematosus

(2009) Luis E. Muñoz et al.   ARTHRITIS AND RHEUMATISM

Type I interferon and lupus

(2009) Lars Rönnblom et al.   CURRENT OPINION IN RHEUMATOLOGY

Poly(ADP-ribose) signals to mitochondrial AIF: A key event in parthanatos

(2009) Yingfei Wang et al.   EXPERIMENTAL NEUROLOGY

Self-RNA–antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8

(2009) Dipyaman Ganguly et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity

(2009) Caspar Ohnmacht et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus

(2009) C. O. Jacob et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus

(2009) D. H. Kono et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding the Epidemiology and Progression of Systemic Lupus Erythematosus

(2009) Guillermo J. Pons-Estel et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Plasmacytoid dendritic cells in the skin: To sense or not to sense nucleic acids

(2009) Curdin Conrad et al.   SEMINARS IN IMMUNOLOGY

Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review

(2008) G Ruiz-Irastorza et al.   ANNALS OF THE RHEUMATIC DISEASES

Dendritic cells and cytokines in human inflammatory and autoimmune diseases

(2008) P BLANCO et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Induction of inflammatory and immune responses by HMGB1–nucleosome complexes: implications for the pathogenesis of SLE

(2008) Vilma Urbonaviciute et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Oligodeoxyribonucleotide-Based Antagonists for Toll-Like Receptors 7 and 9

(2008) Daqing Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Apoptosis in the pathogenesis of systemic lupus erythematosus

(2008) LE Munoz et al.   LUPUS

Nature and functions of autoantibodies

(2008) Keith Elkon et al.   Nature clinical practice. Rheumatology