A novel antagonist of Toll-like receptors 7, 8 and 9 suppresses lupus disease-associated parameters in NZBW/F1 mice

Treatment of systemic lupus erythematosus: new advances in targeted therapy

(2012) Mindy S. Lo et al.   Annals of the New York Academy of Sciences

Polimorphisms in Inflammasome Genes Are Involved in the Predisposition to Systemic Lupus Erythematosus

(2012) Alessandra Pontillo et al.   AUTOIMMUNITY

Toll-Like Receptors and Human Disease: Lessons from Single Nucleotide Polymorphisms

(2012) Yi-Tzu Lin et al.   CURRENT GENOMICS

Human Toll-Like Receptor 8 Can Be Cool Too: Implications for Foreign RNA Sensing

(2012) Soroush T. Sarvestani et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Belimumab: A BLyS-Specific Inhibitor for the Treatment of Systemic Lupus Erythematosus

(2011) G J Dennis   CLINICAL PHARMACOLOGY & THERAPEUTICS

Lupus: Novel therapies in clinical development

(2011) Preeta Kaur Chugh   European Journal of Internal Medicine

Interaction between oxidative stress and chemokines: Possible pathogenic role in systemic lupus erythematosus and rheumatoid arthritis

(2011) Dilip Shah et al.   IMMUNOBIOLOGY

Optimal oligonucleotide sequences for TLR9 inhibitory activity in human cells: lack of correlation with TLR9 binding

(2011) Robert F. Ashman et al.   INTERNATIONAL IMMUNOLOGY

Current and novel therapeutics in the treatment of systemic lupus erythematosus

(2011) Cagri Yildirim-Toruner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mechanism of Endosomal TLR Inhibition by Antimalarial Drugs and Imidazoquinolines

(2011) A. Kuznik et al.   JOURNAL OF IMMUNOLOGY

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

The type I interferon system in the development of lupus

(2011) Lars Rönnblom et al.   SEMINARS IN IMMUNOLOGY

Treatment with a Toll-like receptor inhibitory GpG oligonucleotide delays and attenuates lupus nephritis in NZB/W mice

(2010) Kareem L. Graham et al.   AUTOIMMUNITY

Type I interferons in systemic autoimmunity

(2010) Silvano Sozzani et al.   AUTOIMMUNITY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Tumor Necrosis Factor-α Antagonist Etanercept Decreases Blood Pressure and Protects the Kidney in a Mouse Model of Systemic Lupus Erythematosus

(2010) Marcia Venegas-Pont et al.   HYPERTENSION

Dendritic Cells in Lupus Are Not Required for Activation of T and B Cells but Promote Their Expansion, Resulting in Tissue Damage

(2010) Lino L. Teichmann et al.   IMMUNITY

Oxidative stress in systemic lupus erythematosus: Relationship to Th1 cytokine and disease activity

(2010) Dilip Shah et al.   IMMUNOLOGY LETTERS

TLR9 Regulates TLR7- and MyD88-Dependent Autoantibody Production and Disease in a Murine Model of Lupus

(2010) Kevin M. Nickerson et al.   JOURNAL OF IMMUNOLOGY

The interferon-α signature of systemic lupus erythematosus

(2010) G. Obermoser et al.   LUPUS

Classification, Mechanisms of Action, and Therapeutic Applications of Inhibitory Oligonucleotides for Toll-Like Receptors (TLR) 7 and 9

(2010) Petar S. Lenert   MEDIATORS OF INFLAMMATION

TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus

(2010) Cristiana Guiducci et al.   NATURE

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Inflammasomes and autoimmunity

(2010) Patrick J. Shaw et al.   TRENDS IN MOLECULAR MEDICINE

Regulation of autoreactive B cell responses to endogenous TLR ligands

(2009) Ana Maria Avalos et al.   AUTOIMMUNITY

Endogenous type I interferon inducers in autoimmune diseases

(2009) Doreen Finke et al.   AUTOIMMUNITY

RAGE-independent autoreactive B cell activation in response to chromatin and HMGB1/DNA immune complexes

(2009) Ana M. Avalos et al.   AUTOIMMUNITY

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Modifications Incorporated in CpG Motifs of Oligodeoxynucleotides Lead to Antagonist Activity of Toll-like Receptors 7 and 9

(2009) Dong Yu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Understanding the Epidemiology and Progression of Systemic Lupus Erythematosus

(2009) Guillermo J. Pons-Estel et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

DNA-like class R inhibitory oligonucleotides (INH-ODNs) preferentially block autoantigen-induced B-cell and dendritic cell activation in vitro and autoantibody production in lupus-prone MRL-Faslpr/lpr mice in vivo

(2009) Petar Lenert et al.   ARTHRITIS RESEARCH & THERAPY

Oligodeoxyribonucleotide-Based Antagonists for Toll-Like Receptors 7 and 9

(2008) Daqing Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

The innate immune system in SLE: type I interferons and dendritic cells

(2008) L Rönnblom et al.   LUPUS