The potential to target CCL5/CCR5 in breast cancer

Addition of zoledronic acid to neoadjuvant chemotherapy does not enhance tumor response in patients with HER2-negative stage II/III breast cancer: the NEOZOTAC trial (BOOG 2010-01)

(2014) A. Charehbili et al.   ANNALS OF ONCOLOGY

Chemokines and Chemokine Receptors: Positioning Cells for Host Defense and Immunity

(2014) Jason W. Griffith et al.   Annual Review of Immunology

17β-Estradiol Inhibits Mesenchymal Stem Cells-Induced Human AGS Gastric Cancer Cell Mobility via Suppression of CCL5- Src/Cas/Paxillin Signaling Pathway

(2014) Chao-Hung Kuo et al.   International Journal of Medical Sciences

Disruption of CCR5-Dependent Homing of Regulatory T Cells Inhibits Tumor Growth in a Murine Model of Pancreatic Cancer

(2014) M. C. B. Tan et al.   JOURNAL OF IMMUNOLOGY

Characterization of the Attenuation of Breast Cancer Bone Metastasis in Mice by Zoledronic Acid Using 99mTc bone Scintigraphy

(2014) Chunyu Wu et al.   PATHOLOGY & ONCOLOGY RESEARCH

Myeloid-derived suppressor cells in breast cancer

(2013) Joseph Markowitz et al.   BREAST CANCER RESEARCH AND TREATMENT

Predictive and prognostic factors in locally advanced breast cancer: effect of intratumoral FOXP3+ Tregs

(2013) Lutfiye Demir et al.   CLINICAL & EXPERIMENTAL METASTASIS

Targeting CCL5 in inflammation

(2013) Rafael Elias Marques et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Association of chemotactic factor receptor 5 gene with breast cancer

(2013) Y. Zhang et al.   GENETICS AND MOLECULAR RESEARCH

Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis

(2013) Pallavi Chaturvedi et al.   JOURNAL OF CLINICAL INVESTIGATION

Effect of Genetic Variants in Two Chemokine Decoy Receptor Genes, DARC and CCBP2, on Metastatic Potential of Breast Cancer

(2013) Chen Yang et al.   PLoS One

Tumor Secretion of CCL22 Activates Intratumoral Treg Infiltration and Is Independent Prognostic Predictor of Breast Cancer

(2013) Ya-Qing Li et al.   PLoS One

Mesenchymal stem cell-derived CCL-9 and CCL-5 promote mammary tumor cell invasion and the activation of matrix metalloproteinases

(2013) Muthulekha Swamydas et al.   Cell Adhesion & Migration

CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells

(2012) M. Velasco-Velazquez et al.   CANCER RESEARCH

Tumor-Infiltrating Monocytic Myeloid-Derived Suppressor Cells Mediate CCR5-Dependent Recruitment of Regulatory T Cells Favoring Tumor Growth

(2012) E. Schlecker et al.   JOURNAL OF IMMUNOLOGY

Changes in Chemokine Receptor Expression of Regulatory T Cells After Ex Vivo Culture

(2012) Rikhia Chakraborty et al.   JOURNAL OF IMMUNOTHERAPY

Activation of an IL6 Inflammatory Loop Mediates Trastuzumab Resistance in HER2+ Breast Cancer by Expanding the Cancer Stem Cell Population

(2012) Hasan Korkaya et al.   MOLECULAR CELL

Zoledronic acid blocks the interaction between mesenchymal stem cells and breast cancer cells: implications for adjuvant therapy of breast cancer

(2011) M. Gallo et al.   ANNALS OF ONCOLOGY

Osteopontin promotes CCL5-mesenchymal stromal cell-mediated breast cancer metastasis

(2011) Zhiyong Mi et al.   CARCINOGENESIS

Chemokine control of West Nile virus infection

(2011) Jean K. Lim et al.   EXPERIMENTAL CELL RESEARCH

RB-pathway disruption in breast cancer

(2010) Adam Ertel et al.   CELL CYCLE

Three-Year Safety and Efficacy of Vicriviroc, a CCR5 Antagonist, in HIV-1–Infected Treatment-Experienced Patients

(2010) Timothy J Wilkin et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

c-Jun Induces Mammary Epithelial Cellular Invasion and Breast Cancer Stem Cell Expansion

(2010) Xuanmao Jiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts

(2010) Christophe Ginestier et al.   JOURNAL OF CLINICAL INVESTIGATION

CCL5 promotes proliferation of MCF-7 cells through mTOR-dependent mRNA translation

(2009) Thomas T. Murooka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid Infiltrates Surrounding Primary Breast Tumors and Lead to an Adverse Clinical Outcome

(2009) M. Gobert et al.   CANCER RESEARCH

Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature

(2009) Emmanuelle Charafe-Jauffret et al.   CANCER RESEARCH

CCL19 is a specific ligand of the constitutively recycling atypical human chemokine receptor CRAM-B

(2009) Marion Leick et al.   IMMUNOLOGY

Stromal MCP-1 in mammary tumors induces tumor-associated macrophage infiltration and contributes to tumor progression

(2009) Hiroshi Fujimoto et al.   INTERNATIONAL JOURNAL OF CANCER

The Unexpected Pleiotropic Activities of RANTES

(2009) J. A. Levy   JOURNAL OF IMMUNOLOGY

SDF-1 and CCR5 Genes Polymorphism in Patients with Head and Neck Cancer

(2009) Bijan Khademi et al.   PATHOLOGY & ONCOLOGY RESEARCH

Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity

(2008) K. Movahedi et al.   BLOOD

Imagable 4T1 model for the study of late stage breast cancer

(2008) Kai Tao et al.   BMC CANCER

No Association between Common Chemokine and Chemokine Receptor Gene Variants and Prostate Cancer Risk

(2008) D. C. Petersen et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

A Deletion in the Chemokine Receptor 5(CCR5)Gene Is Associated with Tickborne Encephalitis

(2008) Elin Kindberg et al.   JOURNAL OF INFECTIOUS DISEASES

Genetic Deficiency of Chemokine Receptor CCR5 Is a Strong Risk Factor for Symptomatic West Nile Virus Infection: A Meta‐Analysis of 4 Cohorts in the US Epidemic

(2008) Jean K. Lim et al.   JOURNAL OF INFECTIOUS DISEASES

Chemokine Decoy Receptor D6 Plays a Negative Role in Human Breast Cancer

(2008) F.-Y. Wu et al.   MOLECULAR CANCER RESEARCH

Dachshund inhibits oncogene-induced breast cancer cellular migration and invasion through suppression of interleukin-8

(2008) K. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA